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检索条件"作者=Motoyuki Otsuka"
209 条 记 录,以下是1-10 订阅
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Drug-induced mucosal alterations observed during esophagogastroduodenoscopy
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World Journal of Gastroenterology 2024年 第16期30卷 2220-2232页
作者: Masaya Iwamuro Seiji Kawano motoyuki otsuka Department of Gastroenterology and Hepatology Okayama University Graduate School of MedicineDentistryand Pharmaceutical SciencesOkayama 700-8558Japan
Several features of drug-induced mucosal alterations have been observed in the upper gastrointestinal tract,i.e.,the esophagus,stomach,and duodenum.These include pill-induced esophagitis,desquamative esophagitis,worse... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
Review of oral and pharyngolaryngeal benign lesions detected during esophagogastroduodenoscopy
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World Journal of Gastrointestinal Endoscopy 2023年 第7期15卷 496-509页
作者: Masaya Iwamuro Kenta Hamada Seiji Kawano Yoshiro Kawahara motoyuki otsuka Department of Gastroenterology and Hepatology Okayama University Graduate School of MedicineDentistryand Pharmaceutical SciencesOkayama 700-8558Japan Department of Practical Gastrointestinal Endoscopy Okayama University Graduate School of MedicineDentistryand Pharmaceutical SciencesOkayama 700-8558Japan
Recent advancements in endoscopy equipment have facilitated endoscopists’detection of neoplasms in the oral cavity and pharyngolaryngeal regions.In particular,image-enhanced endoscopy using narrow band imaging or blu... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
Diagnostic and therapeutic application of noncoding RNAs for hepatocellular carcinoma
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World Journal of Hepatology 2015年 第1期7卷 1-6页
作者: Chikako Shibata motoyuki otsuka Takahiro Kishikawa Motoko Ohno Takeshi Yoshikawa Akemi Takata Kazuhiko Koike Department of Gastroenterology Graduate School of MedicineThe University of TokyoTokyo 113-8655Japan Japan Science and Technology Agency PRESTOKawaguchiSaitama 332-0012Japan
Micro RNAs(mi RNAs) are small,noncoding RNA molecules that regulate gene expression posttranscriptionally,targeting thousands of messenger RNAs. Long noncoding RNAs(lnc RNAs),another class of noncoding RNAs,have been ... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
Inflammation and de-differentiation in pancreatic carcinogenesis
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World Journal of Clinical Cases 2018年 第15期6卷 882-891页
作者: Takahiro Seimiya motoyuki otsuka Takuma Iwata Eri Tanaka Tatsunori Suzuki Kazuma Sekiba Mari Yamagami Rei Ishibashi Kazuhiko Koike Department of Gastroenterology Graduate School of Medicine The University of Tokyo
Pancreatic cancer is a malignancy with an extremely poor prognosis. Chronic pancreatitis is a well-known risk factor for pancreatic cancer. Inflammation is thought to influence carcinogenesis through DNA damage and ac... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
Hepatitis B virus pathogenesis: Fresh insights into hepatitis B virus RNA
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World Journal of Gastroenterology 2018年 第21期24卷 2261-2268页
作者: Kazuma Sekiba motoyuki otsuka Motoko Ohno Mari Yamagami Takahiro Kishikawa Tatsunori Suzuki Rei Ishibashi Takahiro Seimiya Eri Tanaka Kazuhiko Koike Department of Gastroenterology Graduate School of MedicineThe University of Tokyo
Hepatitis B virus(HBV) is still a worldwide health concern. While divergent factors are involved in its pathogenesis, it is now clear that HBV RNAs, principally templates for viral proteins and viral DNAs, have divers... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
Circulating RNAs as new biomarkers for detecting pancreatic cancer
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World Journal of Gastroenterology 2015年 第28期21卷 8527-8540页
作者: Takahiro Kishikawa motoyuki otsuka Motoko Ohno Takeshi Yoshikawa Akemi Takata Kazuhiko Koike Department of Gastroenterology Graduate School of Medicine The University of Tokyo Japan Science and Technology Agency PRESTO
Pancreatic cancer remains difficult to treat and has a high mortality rate.It is difficult to diagnose early mainly due to the lack of screening imaging modalities and specific biomarkers.Consequently,it is important ... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
Novel therapeutic approaches for hepatitis B virus covalently closed circular DNA
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World Journal of Gastroenterology 2015年 第23期21卷 7084-7088页
作者: Motoko Ohno motoyuki otsuka Takahiro Kishikawa Takeshi Yoshikawa Akemi Takata Kazuhiko Koike Department of Gastroenterology Graduate School of Medicine the University of Tokyo
Hepatitis B virus(HBV) infection is a major global health problem. Although current therapies, such as the use of nucleos(t)ide analogs, inhibit HBV replication efficiently, they do not eliminate covalently closed cir... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
Hepatic gene expression profiles associated with fibrosis progression and hepatocarcinogenesis in hepatitis C patients
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World Journal of Gastroenterology 2005年 第13期11卷 1995-1999页
作者: Yujin Hoshida motoyuki otsuka Naoya Kato Ryosuke Tateishi Takuma Teratani Shuichiro Shiina Hiroyoshi Taniguchi Masaru Moriyama Takao Kawabe Masao Omata Department of Gastroenterology
AIM: To determine fibrosis progression and hepatocellular carcinoma (HCC), using simultaneous gene expression analysis.METHODS: Total RNA samples were extracted from liver biopsies from 19 patients with hepatitis C vi... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
NF-κB and ERK-signaling pathways contribute to the gene expression induced by cag PAI-positive-Helicobacter pylori infection
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World Journal of Gastroenterology 2005年 第39期11卷 6134-6143页
作者: Wataru Shibata Yoshihiro Hirata Haruhiko Yoshida motoyuki otsuka Yujin Hoshida Keiji Ogura Shin Maeda Tomoya Ohmae Ayako Yanai Yuzo Mitsuno Naohiko Seki Takao Kawabe Masao Omata Department of Gastroenterology Graduate School of Medicine University of TokyoJapan Department of Functional Genomics Graduate School of Medicine University of ChibaJapan
AIM: To elucidate the sequential gene expression profile in AGS cells co-cultured with wild-type Hellcobacter pylori (Hpylon) as a model of H pylori-infected gastric epithelium, and to further examine the contribution... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
Tumor size discrepancy between endoscopic and pathological evaluations in colorectal endoscopic submucosal dissection
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World Journal of Gastrointestinal Endoscopy 2024年 第3期16卷 136-147页
作者: Takeshi Onda Osamu Goto Toshiaki otsuka Yoshiaki Hayasaka Shun Nakagome Tsugumi Habu Yumiko Ishikawa Kumiko Kirita Eriko Koizumi Hiroto Noda Kazutoshi Higuchi Jun Omori Naohiko Akimoto Katsuhiko Iwakiri Department of Gastroenterology Nippon Medical SchoolGraduate School of MedicineBunkyo-ku 113-8603TokyoJapan Endoscopy Center Nippon Medical School HospitalBunkyo-ku 113-8603TokyoJapan Department of Hygiene and Public Health Nippon Medical SchoolBunkyoku 113-8603TokyoJapan Center for Medical Education Nippon Medical SchoolBunkyo-ku 113-8603TokyoJapan
BACKGROUND Tumor size impacts the technical difficulty and histological curability of colorectal endoscopic submucosal dissection(ESD);however,the preoperative evaluation of tumor size is often different from histolog... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论