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Recent Techniques in Management of Lumbosacral Region Tumours: A Prospective Comparative Study

Open Journal of Modern Neurosurgery 2018年第2期8卷 239-249页

作者： mostafa abd elsamea Mohamed Shaaban Ahmed Taha Department of Neurosurgery Al-Azhar University Hospital Damietta Egypt

Background: The lumbosacral plexus consists of the ventral rami from the L2 to S3 nerve roots, with some additions from the L1 and S4 nerve roots as well. The standard treatment for spinal cord compression is urgent surgically decompressive laminectomy over the affected level with resection as much as possible of the exposed tumor to relieve the cord compression. We aim to correlate the impact of preoperative clinical picture, duration of symptoms, and the pathological nature of the lumbo-sacral spine tumors on the outcome of comparative study different modalities of management. Patients and Methods: During the period between 2015 and 2017, thirty cases were studied and surgically managed in Al-Azhar University Hospital, Damietta. Cases were selected for surgery if they were diagnosed as having a symptomatizing lumbosacral lesion. Results: Thirty patients were included in the current study;the commonest lesion in this study was ependymoma eight patients (27%), astrocytoma six patients (20%), and meningioma five patients (17%). Nerve sheath tumor comprised five cases (17%) with the hemangioblastomas three cases (10%), epidermoid one case (3%), and ependymoma of the filum terminale two cases (6%). The mean age of the included patients was 38.96 ± 15.42. The mean duration of lesions was 13.66 ± 10.93. They were 15 male patients (50%), and 15 female patients (50%), with male: female ratio 1:1. The mean duration of symptoms ranged for 1:60 months. The most common presenting manifestations were sensory followed by motor and sphinctric disturbance. Complications occurred in 8 patients (23%), and the most common was postoperative CSF leak. 19 out of 30 cases were surgically totally resected (63%), while 11 cases (37%) were grossly totally resected. Conclusions: Ependymoma and meningioma have more favorable outcome compared to other spinal tumors. Accurate and rapid diagnosis prior to surgery also associated with good outcome.

关键词： Lambosacral Lesion Astrocytoma Ependymoma

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Lumbar Disc Herniation in Pediatric

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Open Journal of Modern Neurosurgery 2018年第2期8卷 233-238页

作者： mostafa abd elsamea Mohamed Shaban Ahmed Taha Samer Elshora Neurosurgery Orthopedic Department Faculty of Medicine (Damietta) Al-Azhar University Egypt

Lumbar disc herniation is a common complaint among adults with degenerated lumbar intervertebral discs, however its incidence in childhood and adolescence is abundant. Findings recommended that pediatric lumbar disc herniation is dissimilar in numerous way from that in adults. It was confirmed that pediatric patients respond to conventional management less than adults, also the consequence of the operation continued to be acceptable for at least 10 years after the first surgery even though it seems to decline somewhat. This retrospective study was undertaken to determine the clinical outcome and the feature of lumbar disc prolapse in pediatric patients. 12 patients younger than 18 years were operated for lumbar disc prolapse in the period from 2012-2016. Patients preoperative data and radiological imaging, operative and postoperative follow up were reviewed. 12 patients were included in this study, 10 were male and 2 females, the average age was 15 years (ranging between 12 - 18 years). The average duration of the symptoms was 11 months. The average follow up was 14 months. All patients had a sciatica prior to surgery, 35% had motor deficit, and 60% had parasthesia. Conservative treatment failed in all patients. After surgery and follow up, improvement occurs in about 80% of patients, ranging from excellent to good, and 20% of patients with fair outcome. According to Pain Visual Analogue Scale, leg pain reduced from 90 - 30 and back pain from 80 - 35. Conclusion: Pediatric lumbar disc herniation is an uncommon object leading to hospitalization. About 0.1% - 0.2% of children and adolescence surgery for lumbar disc herniation in pediatric does not lead to chronic back pain or interfere with physical activity and is related to the excellent short consequence.

关键词： Children Lumbar Disc Herniation Outcome

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The impact of foot reflexology on fatigue and sleep quality in school-aged children undergoing hemodialysis

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Journal of Integrative Nursing 2024年第2期6卷 76-82页

作者： Amal Hashem MOHAMED mostafa SHABAN Huda Hamdy MOHAMMED Randa Mohamed ABOBAKER Salman Hamdan ALSAQRI Rania abd-Elnaby Mohammed ALLAM Faculty of Nursing Minia UniversityMinyaEgypt College of Nursing Jouf UniversitySakakaSaudi Arabia Faculty of Nursing Cairo UniversityGizaEgypt Northern College of Nursing ARARSaudi Arabia College of Nursing University of HailHailSaudi Arabia

Objective:This study aimed to evaluate the effects of foot reflexology on fatigue and sleep quality in school-aged children receiving ***:A quasi-experimental pretest-posttest design was *** children of ages 6-12 undergoing in-center hemodialysis were *** Pittsburgh Sleep Quality Index(PSQI)and Inventory of Fatigue Symptom(IFS)scales were administered at *** then received 30 min of foot reflexology massage before hemodialysis sessions 3 days per week for 12 *** administration of the sleep and fatigue scales occurred after the intervention ***:Reflexology massage led to significant improvements in sleep quality components,including duration(0%-30%normal sleepers),efficiency(0%-50%>85%),latency(50%-0%>60 min),disturbances,and daytime *** mean PSQI score decreased from 18.2 to 9.7(P<0.05).Fatigue severity substantially decreased,with the mean IFS score improving from 105.7 to 64.1(P<0.05).Conclusion:Foot reflexology is an effective nursing intervention for reducing fatigue and improving sleep quality in children on hemodialysis,warranting integration into routine care.

关键词： Fatigue hemodialysis massage pediatric reflexology sleep

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Micropunch grafting for healing of refractory chronic venous leg ulcers

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Chinese Journal Of Plastic and Reconstructive Surgery 2022年第4期4卷 166-170页

作者： Aya Mohamed Samy mostafa abd El-Halim Ahmed Hassan El-Sabbagh Department of Plastic and Reconstructive Surgery Mansoura University HospitalMansoura 35516Egypt Plastic Surgery Center Faculty of MedicineMansoura UniversityMansoura 35516Egypt

Background: Chronic venous ulcers are a serious problem for both patients and physicians. The CEAP classification(clinical manifestations(C), etiologic factors(E), anatomic distribution of disease(A), and underlying pathophysiologic findings(P)) for chronic venous disorders(CVD) was developed in 1994. Published papers on CVD use all or part of the CEAP. Micropunch grafts, which are a variation of skin grafts, have been used with great success in plastic surgery for both esthetic and reconstructive purposes. This study aimed to assess the outcomes of micropunch grafting in the treatment of chronic refractory venous ***: Patients with chronic venous ulcers who did not respond to conservative treatment for more than 6months were included in the study. All patients underwent ulcer coverage by micropunch skin grafts using a micrometer. The patients were discharged on the same day as the surgery. Micropunch skin grafts were manually counted per square centimeter intraoperatively and during follow-up using Dermlite DermatoschopeTM II Pro *** satisfaction was assessed by using a ***: Twenty patients underwent the surgery. Most of the patients were middle-aged males. The ulcers were predominantly small-and medium-sized. The mean operation time was 167.00 ± 86.01 min. After 6 months, the survival rate of the planted micrografts was 84%. Three ulcers had graft loss and two patients had an infection at the ulcer site, which was managed conservatively. The patients were followed-up for 14 ***: Micropunch grafting is a useful and convenient method for the treatment of difficult venous ulcers and can be performed on an outpatient basis.

关键词： Venous ulcer Micropunch grafting

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COVID-19 and hepatic injury: cellular and molecular mechanisms in diverse liver cells

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World Journal of Gastroenterology 2023年第3期29卷 425-449页

作者： Fares E M Ali mostafa K abd El-Aziz Mahmoud M Ali Osama M Ghogar Adel G Bakr Department of Pharmacology and Toxicology Faculty of PharmacyAl-Azhar UniversityAssiut 71524Egypt Department of Pharmacology Al-Azhar UniversityAssiut 71524Egypt Department of Biochemistry Faculty of Pharmacy Badr University in AssiutEgypt

The coronavirus disease 2019(COVID-19)represents a global health and economic *** injuries have been approved to be associated with severe acute respiratory syndrome coronavirus(SARS-CoV-2)*** viral tropism pattern of SARS-CoV-2 can induce hepatic injuries either by itself or by worsening the conditions of patients with hepatic ***,other factors have been reported to play a crucial role in the pathological forms of hepatic injuries induced by SARS-CoV-2,including cytokine storm,hypoxia,endothelial cells,and even some treatments for *** the other hand,several groups of people could be at risk of hepatic COVID-19 complications,such as pregnant women and *** present review outlines and discusses the interplay between SARS-CoV-2 infection and hepatic injury,hepatic illness comorbidity,and risk ***,it is focused on the vaccination process and the role of developed vac-cines in preventing hepatic injuries due to SARS-CoV-2 infection.

关键词： COVID-19 Hepatic injury Viral tropism COVID-19 comorbidity Vaccination

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An Efficient Indoor Localization Based on Deep Attention Learning Model

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Computer Systems Science & Engineering 2023年第8期46卷 2637-2650页

作者： Amr Abozeid Ahmed I.Taloba Rasha M.abd El-Aziz Alhanoof Faiz Alwaghid mostafa Salem Ahmed Elhadad Department of Computer Science College of Science and ArtsJouf UniversityQurayyatSaudi Arabia Information System Department Faculty of Computers and InformationAssiut UniversityEgypt Computer Science Department Faculty of Computers and InformationAssiut UniversityAssiutEgypt Department of Computer Science Faculty of Computers and InformationSouth Valley UniversityQenaEgypt

Indoor localization methods can help many sectors,such as healthcare centers,smart homes,museums,warehouses,and retail malls,improve their service *** a result,it is crucial to look for low-cost methods that can provide exact localization in indoor *** this context,imagebased localization methods can play an important role in estimating both the position and the orientation of cameras regarding an ***-based localization faces many issues,such as image scale and rotation ***,image-based localization’s accuracy and speed(latency)are two critical *** paper proposes an efficient 6-DoF deep-learning model for image-based *** model incorporates the channel attention module and the Scale PyramidModule(SPM).It not only enhances accuracy but also ensures the model’s real-time *** complex scenes,a channel attention module is employed to distinguish between the textures of the foregrounds and *** model adapted an SPM,a feature pyramid module for dealing with image scale and rotation variance ***,the proposed model employs two regressions(two fully connected layers),one for position and the other for orientation,which increases outcome *** on standard indoor and outdoor datasets show that the proposed model has a significantly lower Mean Squared Error(MSE)for both position and *** the indoor 7-Scenes dataset,the MSE for the position is reduced to 0.19 m and 6.25°for the ***,on the outdoor Cambridge landmarks dataset,the MSE for the position is reduced to 0.63 m and 2.03°for the *** to the findings,the proposed approach is superior and more successful than the baseline methods.

关键词： Image-based localization computer vision deep learning attention module VGG-16

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Therapeutic interventions of acute and chronic liver disorders:A comprehensive review

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World Journal of Hepatology 2023年第1期15卷 19-40页

作者： Fares EM Ali mostafa K abd El-Aziz Elham I Sharab Adel G Bakr Department of Pharmacology and Toxicology Faculty of PharmacyAl-Azhar UniversityAssiut BranchAssiut 71524Egypt Faculty of Pharmacy Al-Azhar UniversityAssiut BranchAssiut 71524Egypt

Liver disorders are one of the most common pathological problems *** affects more than 1.5 billion *** types of hepatic cells have been reported to be involved in the initiation and propagation of both acute and chronic liver diseases,including hepatocytes,Kupffer cells,sinusoidal endothelial cells,and hepatic stellate cells(HSCs).In addition,oxidative stress,cytokines,fibrogenic factors,microRNAs,and autophagy are also *** the molecular mechanisms of liver diseases leads to discovering new therapeutic interventions that can be used in ***,antioxidant,anti-inflammatory,anti-HSCs therapy,gene therapy,cell therapy,gut microbiota,and nanoparticles have great potential for preventing and treating liver ***,we explored the recent possible molecular mechanisms involved in the pathogenesis of acute and chronic liver ***,we overviewed the recent therapeutic interventions that targeted liver diseases and summarized the recent studies concerning liver disorders therapy.

关键词： Liver disorders Autophagy Gene therapy Anti-hepatic stellate cells Cell therapy

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Hydrological mass variations in the Nile River Basin from GRACE and hydrological models

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Geodesy and Geodynamics 2019年第6期10卷 430-438页

作者： mostafa abd-Elbaky Shuanggen Jin Shanghai Astronomical Observatory Chinese Academy of SciencesShanghai200030China University of Chinese Academy of Sciences Beijing 100084China Civil Engineering Department Faculty of EngineeringMinia UniversityMinia6111Egypt

Terrestrial water storage(TWS)change is a key component of the global water cycle and hydrologic ***,it is of significance to quantify TWS variations at large scale and understand how the climate changes affect in the water systems,particularly in the Nile River *** this study,TWS variations in the Nile River Basin are estimated and investigated from January 2003 to August 2016 by using the Gravity Recovery and Climate Experiment(GRACE).Also,the Global Land Data Assimilation System(GLDAS)and Tropical Rainfall Measuring Mission(TRMM)are used to understand the causes of the TWS variations in the Nile River Basin(NRB).The peak of precipitation has happened in July and *** one month the appearance of the influence of precipitation on soil moisture is *** the other hand,after two months the same effect of precipitation in TWS is *** the peak of soil moisture has occurred in August and September,the maximum of TWS has observed in September and *** maximum annual TWS from GRACE measurements is 42.66 mm in NRB during September-November(autumn),and its minimum is-33.77 mm during March-May(spring).Also,the maximum annual soil moisture is 25.22 mm in NRB during September-November(autumn),and its minimum is-23.34 mm during March-May(spring)while the peak precipitation is 100.11 mm during June-August(summer)and its minimum is 14.62 mm during December-February(winter).The trend of TWS variations in NRB is 0.04 mm/yr from ***,the TWS variations are mainly dominated by the soil moisture in the Nile River Basin with the correlation coefficient of *** addition,the correlation factor between the non-seasonal TWS and ScPDSI is 0.60,indicating that GRACE-derived TWS well capture the most severe droughts occurred in 2006 and 2011.

关键词： Terrestrial water storage Nile River Basin GRACE TRMM Climate change

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Hybrid of Distributed Cumulative Histograms and Classification Model for Attack Detection

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Computer Systems Science & Engineering 2023年第5期45卷 2235-2247页

作者： mostafa Nassar Anas M.Ali Walid El-Shafai Adel Saleeb Fathi E.abd El-Samie Naglaa F.Soliman Hussah Nasser AlEisa Hossam Eldin H.Ahmed Department of Electronics and Electrical Communications Engineering Faculty of Electronic EngineeringMenoufia UniversityMenouf32952Egypt Alexandria Higher Institute of Engineering&Technology(AIET) AlexandriaEgypt Department of Computer Science Security Engineering LaboratoryPrince Sultan UniversityRiyadh11586Saudi Arabia Department of Information Technology College of Computer and Information SciencesPrincess Nourah Bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Department of Computer Sciences College of Computer and Information SciencesPrincess Nourah Bint Abdulrahman UniversityRiyadhSaudi Arabia

Traditional security systems are exposed to many various attacks,which represents a major challenge for the spread of the Internet in the *** techniques have been suggested for detecting attacks using machine learning and deep *** significant advantage of deep learning is that it is highly efficient,but it needs a large training time with a lot of ***,in this paper,we present a new feature reduction strategy based on Distributed Cumulative Histograms(DCH)to distinguish between dataset features to locate the most effective *** histograms assess the dataset instance patterns of the applied features to identify the most effective attributes that can significantly impact the classification *** different models for detecting attacks using Convolutional Neural Network(CNN)and Long Short-Term Memory Network(LSTM)are also *** accuracy test of attack detection using the hybrid model was 98.96%on the UNSW-NP15 *** proposed model is compared with wrapper-based and filter-based Feature Selection(FS)*** proposed model reduced classification time and increased detection accuracy.

关键词： Feature selection DCH LSTM CNN security systems

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Enhancing Parkinson’s Disease Diagnosis Accuracy Through Speech Signal Algorithm Modeling

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Computers, Materials & Continua 2022年第2期70卷 2953-2969页

作者： Omar M.El-Habbak abdelrahman M.abdelalim Nour H.Mohamed Habiba M.abd-Elaty mostafa A.Hammouda Yasmeen Y.Mohamed Mohanad A.Taifor Ali W.Mohamed School of Information Technology and Computer Science Nile UniversityGiza12677Egypt Operations Research Department Faculty of Graduate Studies for Statistical ResearchCairo UniversityGiza12613Egypt Wireless Intelligent Networks Center(WINC) School of Engineering and Applied SciencesNile UniversityGiza12677Egypt

Parkinson’s disease(PD),one of whose symptoms is dysphonia,is a prevalent neurodegenerative *** use of outdated diagnosis techniques,which yield inaccurate and unreliable results,continues to represent an obstacle in early-stage detection and diagnosis for clinical professionals in the medical *** solve this issue,the study proposes using machine learning and deep learning models to analyze processed speech signals of patients’voice *** of these processed speech signals were obtained and experimented on by random forest and logistic regression *** were highly successful,with 90%accuracy produced by the random forest classifier and 81.5%by the logistic regression ***,a deep neural network was implemented to investigate if such variation in method could add to the *** proved to be effective,as the neural network yielded an accuracy of nearly 92%.Such results suggest that it is possible to accurately diagnose early-stage PD through merely testing patients’*** research calls for a revolutionary diagnostic approach in decision support systems,and is the first step in a market-wide implementation of healthcare software dedicated to the aid of clinicians in early diagnosis of PD.

关键词： Early diagnosis logistic regression neural network Parkinson’s disease random forest speech signal processing algorithms

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