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The flattening of spacetime hierarchy of the N,N-dimethyltryptamine brain state is characterized by harmonic decomposition of spacetime(HADES) framework

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National Science Review 2024年第5期11卷 46-55页

作者： Jakub Vohryzek Joana Cabral Christopher Timmermann Selen Atasoy leor Roseman David J.Nutt Robin l.Carhart-Harris Gustavo Deco morten l.kringelbach Centre for Eudaimonia and Human Flourishing Linacre CollegeDepartment of Psychiatry University of Oxford Department of Psychiatry University of Oxford Center for Music in the Brain Aarhus University Center for Brain and Cognition Computational Neuroscience GroupDepartment of Information and Communication TechnologiesUniversitat Pompeu Fabra life and Health Sciences Research Institute School of MedicineUniversity of Minho ICVS/3B's-PT Government Associate laboratory Centre for Psychedelic Research Department of Brain Sciences Imperial College London Departments of Neurology and Psychiatry University of California San Francisco Institució Catalana de la Recerca i Estudis Avan?ats (ICREA) Department of Neuropsychology Max Planck Institute for Human Cognitive and Brain Sciences School of Psychological Sciences Monash University

The human brain is a complex system, whose activity exhibits flexible and continuous reorganization across space and time. The decomposition of whole-brain recordings into harmonic modes has revealed a repertoire of gradient-like activity patterns associated with distinct brain functions. However, the way these activity patterns are expressed over time with their changes in various brain states remains unclear. Here, we investigate healthy participants taking the serotonergic psychedelic N,N-dimethyltryptamine(DMT) with the Harmonic Decomposition of Spacetime(HADES) framework that can characterize how different harmonic modes defined in space are expressed over time. HADES demonstrates significant decreases in contributions across most low-frequency harmonic modes in the DMT-induced brain state. When normalizing the contributions by condition(DMT and non-DMT), we detect a decrease specifically in the second functional harmonic, which represents the uni-to transmodal functional hierarchy of the brain,supporting the leading hypothesis that functional hierarchy is changed in psychedelics. Moreover, HADES'dynamic spacetime measures of fractional occupancy, life time and latent space provide a precise description of the significant changes of the spacetime hierarchical organization of brain activity in the psychedelic state.

关键词： spatio-temporal brain dynamics DMT harmonic modes

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Vortex lattices in type-II superconductors studied by small-angle neutron scattering

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Frontiers of physics 2011年第4期6卷 398-409页

作者： morten Ring Eskildsen Department of Physics University of Notre Dame Notre Dame IN 46556 USA

Here we review recent small-angle scattering studies of the vortex lattice in a range of type-II superconductors carried out by our group. Emphasis is placed on providing examples of the kind of information which can be obtained by such measurements, focusing in particular on studies of the vortex lattice structure and form factor in luNi2B2C, TmNi2B2C, CeCoIn5 and Ba（Fe0.93Co0.07）2As2.

关键词： superconductivity vortex lattice small-angle neutron scattering borocarbides pnic-tides CeCoIn5

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Patients with inflammatory bowel disease have increased risk of autoimmune and inflammatory diseases

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World Journal of Gastroenterology 2017年第33期23卷 6137-6146页

作者： morten l Halling Jens Kjeldsen Torben Knudsen Jan Nielsen lars Koch Hansen Department of Gast-roenterology and Hepatology Hospital of Southwest Jutland Department of Medical Gastroenterology S Odense University Hospital Center for Clinical Epidemiology Odense Uni-versity Hospital

AIM To investigate whether immune mediated diseases(IMD) are more frequent in patients with inflammatory bowel disease(IBD).METHODS In this population based registry study,a total of 47325 patients with IBD were alive and registered in the Danish National Patient Registry on December 16,2013. Controls were randomly selected from the Danish Civil Registration System(CRS) and matched for sex,age,and municipality. We used ICD 10 codes to identify the diagnoses of the included patients. The IBD population was divided into three subgroups: Ulcerative colitis(UC),Crohn's disease(CD) and Both the latter referring to those registered with both diagnoses. Subsequently,odds-ratios(OR) and 95%CI were obtained separately for each group and their respective controls. The use of Bonferoni post-test correction adjusted the significance level to P lues were estimated using Fisher's exact *** There were significantly more women than men in the registry,and a greater percentage of comorbidity in the IBD groups(P ll significantly more frequent in the IBD group. Sixteen were associated with UC versus twelve with CD. In both UC and CD ORs were significantly increased(P lerosing cholangitis(PSC),celiac disease,type 1 diabetes(T1D),sarcoidosis,asthma,iridocyclitis,psoriasis,pyoderma gangrenosum,rheumatoid arthritis,and ankylosing spondylitis. Restricted to UC(P liary cholangitis,Grave's disease,polymyalgia rheumatica,temporal arteritis,and atrophic gastritis. Restricted to CD(P leritis. Restricted to women with UC(P l arteritis,and polymyalgia rheumatica. Restricted to women with CD were episcleritis,rheumatoid arthritis,and psoriatic arthritis. The only disease restricted to men(P lUSION Immune mediated diseases were si

关键词： Immune mediated diseases Ulcerative colitis Risk Prevalence Registry Chronic inflammatory diseases Autoimmune diseases Inflammatory bowel disease Crohn’s disease extraintestinal manifestations

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Predicting glass structure by physics-informed machine learning

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npj Computational Materials 2022年第1期8卷 1839-1847页

作者： Mikkel l.Bødker Mathieu Bauchy Tao Du John C.Mauro morten M.Smedskjaer Department of Chemistry and Bioscience Aalborg University9220AalborgDenmark Physics of AmoRphous and Inorganic Solids laboratory(PARISlab) Department of Civil and Environmental EngineeringUniversity of CaliforniaLos AngelesCA90095USA Department of Materials Science and Engineering The Pennsylvania State UniversityUniversity ParkPA16802USA

Machine learning(Ml)is emerging as a powerful tool to predict the properties of materials,including *** Ml models with knowledge of how glass composition affects short-range atomic structure has the potential to enhance the ability of composition-property models to extrapolate accurately outside of their training ***,we introduce an approach wherein statistical mechanics informs a Ml model that can predict the non-linear composition-structure relations in oxide *** combined model offers an improved prediction compared to models relying solely on statistical physics or machine learning ***,we show that the combined model accurately both interpolates and extrapolates the structure of Na_(2)O–SiO_(2)***,the model is able to extrapolate predictions outside its training set,which is evidenced by the fact that it is able to predict the structure of a glass series that was kept fully hidden from the model during its training.

关键词： glasses structure glass

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Predicting solid state material platforms for quantum technologies

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npj Computational Materials 2022年第1期8卷 1983-1997页

作者： Oliver lerstøl Hebnes Marianne Etzelmüller Bathen Øyvind Sigmundson Schøyen Sebastian GWinther-larsen lasse Vines morten Hjorth-Jensen Sopra Steria Information Technology and ServicesN-4020StavangerNorway Department of Physics and Center for Computing in Science Education University of OsloN-0316OsloNorway Advanced Power Semiconductor laboratory ETH Zürich8092ZürichSwitzerland Menon Economics N-0369OsloNorway Department of Physics and Center for Materials Science and Nanotechnology University of OsloN-0316OsloNorway Department of Physics and Astronomy and Facility for Rare Isotope Beams Michigan State UniversityEast LansingMI48824USA

Semiconductor materials provide a compelling platform for quantum technologies(QT).However,identifying promising material hosts among the plethora of candidates is a major ***,we have developed a framework for the automated discovery of semiconductor platforms for QT using material informatics and machine learning *** approaches were implemented to label data for training the supervised machine learning(Ml)algorithms logistic regression,decision trees,random forests and gradient *** find that an empirical approach relying exclusively on findings from the literature yields a clear separation between predicted suitable and unsuitable *** contrast to expectations from the literature focusing on band gap and ionic character as important properties for QT compatibility,the Ml methods highlight features related to symmetry and crystal structure,including bond length,orientation and radial distribution,as influential when predicting a material as suitable for QT.

关键词： quantum symmetry separation

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lG集团:继承纠纷中的财阀家族

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家族企业 2024年第4期 71-72页

作者：莫顿·班纳德森布莱恩·亨利欧洲工商管理学院经济学哥本哈根大学经济学欧洲工商管理学院哥本哈根大学

一场与税务机关的继承税纠纷让家族女性继承人们意外发现了被隐螨的真相。在韩国有这样一种说法,“一个人可以在三星的医院出生,在三星的太平间结束一生”,说明财阀(商业集团)的影响力在韩国人的日常生活中无处不在。“财阀”一词意为... 详细信息

一场与税务机关的继承税纠纷让家族女性继承人们意外发现了被隐螨的真相。在韩国有这样一种说法,“一个人可以在三星的医院出生,在三星的太平间结束一生”,说明财阀(商业集团)的影响力在韩国人的日常生活中无处不在。“财阀”一词意为“金钱派系”或“财富集团”,但财阀不仅仅是一家公司,在韩国文化中,财阀就是“王朝”。

关键词：继承纠纷税务机关财阀三星韩国继承税家族

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Highly Efficient l-Band Fibre -DFB lasers

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光学学报 2003年第S1期23卷 379-380页

作者： morten Ibsen David J. Richardson David N. Payne ORC - University of Southampton Southampton SO17 1BJ United Kingdom. Also with Southampton Photonics Ltd. Southampton SO16 4NS United Kingdom.ORC - University of Southampton Southampton SO17 1BJ United Kingdom. Also with Southampton Photonics Ltd. Southampton SO16 4NS United Kingdom.ORC - University of Southampton Southampton SO17 1BJ United Kingdom. Also with Southampton Photonics Ltd. Southampton SO16 4NS United Kingdom.

A more than 12 mW highly efficient fibre-DFB laser operating at 1618.3 nm is fabricated and characterised. Its high-power, low-noise and single-polarisation characteristics make it very suitable WDM-source for l-band ... 详细信息

关键词： DFB lasers high in for Highly Efficient l-Band Fibre WDM RIN

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Guild composition and habitat use of voles in 2 forest landscapes in south-eastern Norway

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Integrative Zoology 2011年第4期6卷 299-310页

作者： lucrezia GORINI John D.C.lINNEll luigi BOITANI Ulrike HAUPTMANN morten ODDEN Per WEGGE Erlend B.NIlSEN Department of Animal and Human Biology Sapienza University of RomeRomeItaly Faculty of Applied Ecology and Agricultural Sciences Hedmark University CollegeCampus EvenstadKoppangNorway Norwegian Institute for Nature Research TrondheimNorway Department of Ecology and Natural Resource Management Norwegian University of Life SciencesÅsNorway

It is widely believed that intensive forestry has influenced small mammal population dynamics,and thereby the entire mammalian community in Fennoscandian boreal *** nature of these impacts on the different species is subject to *** live-trapped voles between 2006 and 2009 in 2 commercially harvested forests in south-eastern *** investigated the variation in vole abundance among habitat types(*** forest and clear-cut)and the hypothesis that graminivorous species such as field voles(Microtus agrestis l.)benefit from clear-cuts at the expense of forest dwellers(*** bank vole,Myodes glareolus Schreb.),using fine-scale descriptors of the ground *** could not find support for the hypothesis that field voles show a preference for clear-cuts,and their overall abundance was low,while bank voles were the dominant species in all habitat types,including clear-cuts in the peak and pre-peak *** found a positive association between bank vole abundance and bilberry(Vaccinium myrtillus l.)availability rather than a specific habitat *** field vole density in clear-cuts might be due to variation in local productivity and ground vegetation as well as to large variation in the species temporal *** latter is particularly associated with the widespread decline of field voles in *** has the potential to negatively affect bank vole population dynamics because of the negative effect on bilberry development.

关键词： bank vole bilberry clear-cut field vole forestry

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The Road to the Beijing Winter Olympics and Beyond: Opinions and Perspectives on Physiology and Innovation in Winter Sport

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Journal of Science in Sport and Exercise 2021年第4期3卷 321-331页

作者： Jun Wang Hongwei Guan morten Hostrup David S.Rowlands Jose Gonzalez-Alonso Jørgen Jensen Department of Exercise Physiology Beijing Sport UniversityBeijingChina Department of Health Promotion and Physical Education School of Health Sciences and Human PerformanceIthaca CollegeIthacaNY 14850USA Section of Integrative Physiology Department of NutritionExercise and SportsUniversity of CopenhagenCopenhagenDenmark School of Sport Exerciseand NutritionCollege of HealthMassey UniversityAucklandNew Zealand Centre for Human Performance Exercise and RehabilitationBrunel University LondonUxbridgeUK Department of Physical Performance Norwegian School of Sport SciencesUllevål StadionP.O.Box 40120806 OsloNorway

Beijing will host the 2022 Winter Olympics,and China strengthens research on various aspects to allow their athletes to compete successfully in winter ***,Government-directed initiatives aim to increase public participation in recreational winter *** parallel developments allow research to advance knowledge and understanding of the physiological determinants of performance and health related to winter *** sport athletes often conduct a substan-tial amount of training with high volumes of low-to-moderate exercise intensity and lower volumes of high-intensity ***,much of the training occur at low ambient temperatures and winter sport athletes have high risk of developing asthma or asthma-related conditions,such as exercise-induced *** high training volumes require optimal nutrition with increased energy and dietary protein requirement to stimulate muscle protein synthesis response in the post-exercise *** higher protein intake is required in the cold should be ***-country ski-ing is performed mostly in Northern hemisphere with a strong cultural heritage and sporting *** is expected that innovative initiatives on recruitment and training during the next few years will target to enhance performance of Chinese athletes in classical endurance-based winter *** innovation potential coupled with resourcing and population may be substantial with the potential for China to become a significant winter sport *** paper discusses the physiological aspects of endurance training and performance in winter sport highlighting areas where innovation may advance in athletic performance in cold *** addition,to ensure sustainable development of snow sport,a quality ski patrol and rescue system is recommended for the safety of increasing mass participation.

关键词： Exercise physiology Endurance training Maximal oxygen uptake Temperature Protein Asthma Cross-country skiing Ski patrol

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CIMMYT普通小麦籽粒硬度等位变异的检测

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作物学报 2005年第10期31卷 1277-1283页

作者：陈锋何中虎 morten lillemo 夏先春中国农业科学院作物研究科学所/国家小麦改良中心北京100081 国际玉米小麦改良中心

籽粒硬度主要由5D染色体短臂的1对主效基因Ha控制,研究籽粒硬度等位变异有助于提高小麦的磨粉和食品加工品质。本试验对国际玉米小麦改良中心(CIMMYT)的138份历史品种和代表性高代品系的硬度基因型进行了研究。在用SDS-PAGE鉴定Pina-D1 ... 详细信息

籽粒硬度主要由5D染色体短臂的1对主效基因Ha控制,研究籽粒硬度等位变异有助于提高小麦的磨粉和食品加工品质。本试验对国际玉米小麦改良中心(CIMMYT)的138份历史品种和代表性高代品系的硬度基因型进行了研究。在用SDS-PAGE鉴定Pina-D1 b/Pinb-D1 a时,用10%甘油代替水配制分离胶,用PDA代替甲叉配制分离胶和浓缩胶,增强了PINA和PINB两种蛋白带型的分辨率。结果表明,与其他国家硬质麦中Pina-D1 a/Pinb-D1 b类型偏多的特点明显不同,CIMMYT硬质小麦中puroindoline a(PINA)蛋白缺失类型(或称Pina-D1 b/Pinb-D1 a)较多,为118个,占85.5%;Pina-D1 a/Pinb-D1 a(野生型)为11个,占8.0%;Pina-D1 a/Pinb-D1 b类型有9个,占6.5%。其中,PINA缺失对小麦籽粒硬度的影响最大,与其他2种基因型硬度值之间差异达5%显著水平。先前研究结果表明,PINA蛋白缺失类型的磨粉品质和面包烘烤品质均劣于Pina-D1 a/Pinb-D1 b类型,因此建议CIMMYT多引进一些其他硬度变异类型的小麦种质,如Pina-D1 a/Pinb-D1 b类型等,以改善其硬度基因型过度单一的局面,从而减少PINA蛋白缺失带来的不利影响。同时,也提醒我国以其他用途如抗病、抗旱等为目的引种CIMMYT小麦时,还应充分考虑PINA蛋白缺失对磨粉和加工品质的不利影响,以更合理引进和有效利用CIMMYT种质资源。

关键词：普通小麦籽粒硬度等位变异 puroindoline蛋白 STS标记

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