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Automated Artificial Intelligence Empowered White Blood Cells Classification model

Computers, materials & Continua 2023年第4期75卷 409-425页

作者： mohammad Yamin Abdullah m.Basahel mona Abusurrah Sulafah m Basahel Sachi Nandan mohanty E.Laxmi Lydia Faculty of Economics and Administration King Abdulaziz UniversityJeddahSaudi Arabia Department of management Information Systems College of Business AdministrationTaibah UniversityAl-MadinahSaudi Arabia E-commerce Department College of Administrative and Financial SciencesSaudi Electronic UniversityJeddahSaudi Arabia School of Computer Science&Engineering(SCOPE) VIT-AP UniversityAmaravatiAndhra PradeshIndia Department of Computer Science and Engineering Vignan’s Institute of Information Technology(Autonomous)VisakhapatnamAndhra Pradesh530049India

White blood cells (WBC) or leukocytes are a vital component ofthe blood which forms the immune system, which is accountable to fightforeign elements. The WBC images can be exposed to different data analysisapproaches which categorize different kinds of WBC. Conventionally, laboratorytests are carried out to determine the kind of WBC which is erroneousand time consuming. Recently, deep learning (DL) models can be employedfor automated investigation of WBC images in short duration. Therefore,this paper introduces an Aquila Optimizer with Transfer Learning basedAutomated White Blood Cells Classification (AOTL-WBCC) technique. Thepresented AOTL-WBCC model executes data normalization and data augmentationprocess (rotation and zooming) at the initial stage. In addition,the residual network (ResNet) approach was used for feature extraction inwhich the initial hyperparameter values of the ResNet model are tuned by theuse of AO algorithm. Finally, Bayesian neural network (BNN) classificationtechnique has been implied for the identification of WBC images into distinctclasses. The experimental validation of the AOTL-WBCC methodology isperformed with the help of Kaggle dataset. The experimental results foundthat the AOTL-WBCC model has outperformed other techniques which arebased on image processing and manual feature engineering approaches underdifferent dimensions.

关键词： White blood cells cell engineering computational intelligence image classification transfer learning

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The impact of male overweight on semen quality and outcome of assisted reproduction

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Asian Journal of Andrology 2014年第5期16卷 749-754,I0010页

作者： Lise Thomsen Peter Humaidan Leif Bungum mona Bungum The Fertility Clinic Viborg Hospital Skive Aarhus University Faculty of Health Aarhus N The Fertility Clinic Herlev Hospital Herlev Denmark Reproductive medicine Centre Skanes University Hospital Malmo Sweden

It is well-documented that male overweight and obesity causes endocrine disorders that might diminish the male reproductive capacity; however, reports have been conflicting regarding the influence of male body mass index （BmI） on semen quality and the outcome of assisted reproductive technology （ART）. The aim of this study was to investigate whether increased male BmI affects sperm quality and the outcome of assisted reproduction in couples with an overweight or obese man and a non-obese partner. Data was prospectively collected from 612 infertile couples undergoing ART at a Danish fertility center. Self-reported information on paternal height and weight were recorded and BmI was calculated. The men were divided into four BmI categories： underweight BmI 〈 20 kgm^-2, normal BmI 20-24.9 kg m^-2, overweight BmI 25-29.9 kgm^-2 and obese BmI 〉 30 kgm^-2. Conventional semen analysis was performed according to the World Health Organization guideline and sperm DNA integrity was analyzed by the Sperm Chromatin Structure Assay （SCSA）. No statistically significant effect of male BmI was seen on conventional semen parameters （sperm concentration, total sperm count, seminal volume and motility） or on SCSA-results. Furthermore, the outcome of ART regarding fertilization rate, number of good quality embryos （GQE）, implantation and pregnancy outcome was not influenced by the increasing male BmIo

关键词： assisted reproductive technology body mass index male obesity sperm chromatin structure assay sperm quality

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modification of Serum Galectin-3 and Reversal of Cardiac Remodeling Following Pediatric Transcatheter Atrial Septal Defect Closure

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Congenital Heart Disease 2022年第2期17卷 173-185页

作者： Omnia Shafei Alyaa A.Kotby mona mEl Ganzoury Nevin m.Habeeb Eman Elsayed Department of Pediatrics Faculty of MedicineAin Shams UniversityCairoEgypt Children’s Hospital Cardiology UnitAin Shams University HospitalsCairoEgypt

Objectives:We aimed to evaluate the effect of percutaneous atrial septal defect(ASD)closure in children using right heart indices and serum galectin-3(Gal-3),as potential biomarkers of right heart ***:This case–control prospective study included 40 children with ASD and 25 control *** echocardiographic evaluation was performed before the procedure,as well as 24 h,1 month,and 6 months after *** Gal-3 was measured before,and 1 month after the ***:Serum Gal-3 concentration,right atrial(RA)dimensions,right ventricular(RV)dimensions,indexed RA area,and right index of myocardial performance(RImP)were significantly increased in children with ASD compared with control subjects while tricuspid annular plane systolic excursion(TAPSE)was significantly *** months after closure,RA,and RV dimensions significantly decreased and RVfunction improved(RImP decreased and TAPSE increased).Gal-3 oncentration significantly decreased 1 month after ASD closure,but it did not reach normal range compared with control subjects.A positive correlation between Gal-3 and age at closure,RA area,RV dimensions,and RImP was observed.A positive correlation was observed between the decrease in Gal-3 concentration and the decrease in RA area and RV dimensions 1 month after ASD closure.A significant negative correlation was observed between TAPSE and Gal-3 concentration before and after ***:Percutaneous ASD closure can improve right-sided indices and decrease serum Gal-3 ***-3 can be used as a sensitive biomarker of right heart remodeling,with a decrease in Gal-3 concentration suggesting reversal of maladaptive remodeling.

关键词： Percutaneous device closure Galectin-3 cardiac remodeling children atrial septal defect

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maternal vitamin D level and vitamin D receptor gene polymorphism as a risk factor for congenital heart diseases in offspring;An Egyptian case-control study

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Genes & Diseases 2019年第2期6卷 193-200页

作者： Wesam A.mokhtar Amal Fawzy Reem m.Allam Rania m.Amer mona S.Hamed Pediatric Department Faculty of MedicineZagazig UniversityEgypt medical Biochemistry Department Faculty of MedicineZagazig UniversityEgypt Clinical Pathology Department Faculty of MedicineZagazig UniversityEgypt medical microbiology and Immunology Department Faculty of MedicineZagazig UniversityEgypt Public Health and Community medicine Faculty of MedicineZagazig UniversityEgypt

Vitamin D&vitamin D receptor(VDR)signaling play a very crucial role in early embryonic heart *** construct this case-control study to investigate the association between maternal serum vitamin D level&VDR gene Fok1 polymorphism and risk of congenital heart defects(CHD)in *** mothers who had term neonates with CHD were considered as *** age-comparable healthy mothers who had neonates without CHD were contemplated as *** serum 25 hydroxyvitamin D[25(OH)D]level was tested using *** VDR gene Fok1 polymorphism was analyzed using PCR-based *** was a significant decrease in maternal vitamin D level(P=0.002)and a significant increase in vitamin D deficient status(P=0.007)among cases when compared to *** gene Fok1 genotypes distribution frequency were in accordance with Hardy Weinberg equilibrium(HW)among controls.A significant increase in VDR gene Fok1 F/f&f/f genotypes and f allele were observed in cases compared to controls with estimated odds ratio(95%confidence interval)&P-value of 3(1e8)&P=0.006,11(1e97)&P=0.01 and 3(2e6)&P=0.001 *** was a significant decrease in maternal vitamin D level in neonates with cyanotic CHD(P=0.000)compared to those with a cyanotic CHD while there was no significant difference in VDR Fok1 genotype(P=0.18)&allele(P=0.05)distribution between two *** concluded that maternal vitamin D deficiency and VDR gene Fok1 F/f,f/f genotype and f allele were associated with increased risk of CHD in offspring.

关键词： Congenital heart disease FoK1 polymorphism Vitamin D Vitamin D receptor gene maternal vitamin D

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Biological treatments as a mean to improve feed utilization in agriculture animals——An overview

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Journal of Integrative Agriculture 2015年第3期14卷 534-543页

作者： Nahla A Abdel-Aziz Abdelfattah Z m Salem mounir m El-Adawy Luis m Camacho Ahmed E Kholif mona m Y Elghandour Borhami E Borhami Department of Animal and Fish Production Faculty of Agriculture Alexandria University Faculty of Veterinary medicine and Animal Science Autonomous University of the State of Mexico Dairy Science Department National Research Centre Faculty of Veterinary and Livestock Autonomous University of Guerrero

As a result of agriculture practices, million tons of agriculture are produced as a secondary or by-products; however, with low nutritive values. many methods are applied to improve the nutritive value and increase its utilization in ruminant＇s nutrition. The biological treatments are the most common with more safe-treated products. In most cases, the biological treatments are paralleled with decreased crude fiber and fiber fractions content with increased crude protein content. Direct-fed microbial and exogenous enzymes to animal are other ways of biological methods for improving nutritive value of feeds. Here in this review, we will try to cover the biological treatments of by-products from different sides view with different types of animals and different animal end-products.

关键词： biological treatment by-products nutrition nutritive values

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Epidemiology of type 2 diabetes in the middle East and North Africa:Challenges and call for action

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World Journal of Diabetes 2021年第9期12卷 1401-1425页

作者： Imad m El-Kebbi Nayda H Bidikian Layal Hneiny mona Philippe Nasrallah Department of Internal medicine Division of EndocrinologyAmerican University of Beirut Medical CenterFaculty of MedicineBeirut 11072020Lebanon Department of Internal medicine Sheikh Shakhbout Medical CityAbou Dhabi 11001United Arab Emirates School of medicine American University of BeirutFaculty of MedicineBeirut 11072020Lebanon University Libraries Saab Medical LibraryAmerican University of BeirutBeirut 11072020Lebanon

Type 2 diabetes continues to be a serious and highly prevalent public health problem *** 2019,the highest prevalence of diabetes in the world at 12.2%,with its associated morbidity and mortality,was found in the middle East and North Africa *** addition to a genetic predisposition in its population,evidence suggests that obesity,physical inactivity,urbanization,and poor nutritional habits have contributed to the high prevalence of diabetes and prediabetes in the *** risk factors have also led to an earlier onset of type 2 diabetes among children and adolescents,negatively affecting the productive years of the youth and their quality of ***,efforts to control the rising prevalence of diabetes and its complications have been challenged and complicated by the political instability and armed conflict in some countries of the region and the recent coronavirus disease *** strategies,coupled with targeted interventions at the regional,national,and community levels are needed to address and curb the spread of this public health crisis.

关键词： Type 2 diabetes middle East and North Africa Epidemiology Prevalence Prediabetes Complications

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Symbiotic Organisms Search with Deep Learning Driven Biomedical Osteosarcoma Detection and Classification

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Computers, materials & Continua 2023年第4期75卷 133-148页

作者： Abdullah m.Basahel mohammad Yamin Sulafah m.Basahel mona m.Abusurrah K.Vijaya Kumar E.Laxmi Lydia Faculty of Economics and Administration King Abdulaziz UniversityJeddahSaudi Arabia E-Commerce Department College of Administrative and Financial SciencesSaudi Electronic UniversityJeddahSaudi Arabia Department of management Information Systems College of Business AdministrationTaibah UniversityAl-MadinahSaudi Arabia Department of Computer Science and Engineering GITAM School of TechnologyVisakhapatnam CampusGITAM(Deemed to be a University)India Department of Computer Science and Engineering GMR Institute of TechnologyAndhra PradeshRajamIndia

Osteosarcoma is one of the rare bone cancers that affect the individualsaged between 10 and 30 and it incurs high death rate. Early diagnosisof osteosarcoma is essential to improve the survivability rate and treatmentprotocols. Traditional physical examination procedure is not only a timeconsumingprocess, but it also primarily relies upon the expert’s *** this background, the recently developed Deep Learning (DL) models canbe applied to perform decision making. At the same time, hyperparameteroptimization of DL models also plays an important role in influencing overallclassification performance. The current study introduces a novel SymbioticOrganisms Search with Deep Learning-driven Osteosarcoma Detection andClassification (SOSDL-ODC) model. The presented SOSDL-ODC techniqueprimarily focuses on recognition and classification of osteosarcoma usinghistopathological images. In order to achieve this, the presented SOSDL-ODCtechnique initially applies image pre-processing approach to enhance the qualityof image. Also, mobileNetv2 model is applied to generate a suitable groupof feature vectors whereas hyperparameter tuning of mobileNetv2 modelis performed using SOS algorithm. At last, Gated Recurrent Unit (GRU)technique is applied as a classification model to determine proper class *** order to validate the enhanced osteosarcoma classification performance ofthe proposed SOSDL-ODC technique, a comprehensive comparative analysiswas conducted. The obtained outcomes confirmed the betterment of SOSDLODCapproach than the existing approaches as the former achieved a maximumaccuracy of 97.73%.

关键词： Osteosarcoma medical imaging deep learning feature vectors computer aided diagnosis image classification

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A unique circular path of moving single bubble sonoluminescence in water

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Chinese Physics B 2011年第7期20卷 252-258页

作者： Rasoul Sadighi-Bonabi mona mirheydari Homa Ebrahimi Nastaran Rezaee Lida Nikzad Department of Physics Sharif University of TechnologyTehran 11365-91Iran Department of Physics Islamic Azad University Central Tehran BranchTehran 14676-86831Iran Laser and Optics Research School Tehran 14676-86831Iran

Based on a quasi-adiabatic model, the parameters of the bubble interior for a moving single bubble sonoluminescence （m-SBSL） in water are calculated. By using a complete form of the hydrodynamic force, a unique circular path for the m-SBSL in water is obtained. The effect of the ambient pressure variation on the bubble trajectory is also investigated. It is concluded that as the ambient pressure increases, the bubble moves along a circular path with a larger radius and all bubble parameters, such as gas pressure, interior temperature and light intensity, increase. A comparison is made between the parameters of the moving bubble in water and those in N-methylformamide. With fluid viscosity increasing, the circular path changes into an elliptic form and the light intensity increases.

关键词： sonoluminescence bubble trajectory fluid viscosity bremsstrahlung

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In vitro Ruminal Gas Production Kinetics of Four Fodder Trees Ensiled With or Without molasses and Urea

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Journal of Integrative Agriculture 2013年第7期12卷 1234-1242页

作者： Abdelfattah Z m Salem ZHOU Chuan-she TAN Zhi-liang miguel mellado moises Cipriano Salazar mona m m Y Elghandopur Nicholas E Odongo Faculty of Veterinary and Livestock Autonomous University of the State of Mexico Key Laboratory of Agro-ecological Processes in Subtropical Region Institute of Subtropical Agriculture Chinese Academy of Sciences Department of Animal Nutrition Autonomous Agrarian University Antonio Narro Faculty of Veterinary and Livestock Autonomous University of Guerrero

This study investigated if the addition of urea （U）, molasses （m） or their 1：1 （v/v） mixture during ensiling increases the nutritional value of forage from four fodder trees （Prunus persica, Leucaena esculenta, Acacia farnesiana, and Prunus domestica）. Forage samples of fodder trees were collected in triplicate （three individual samples of each species） and subjected to an in vitro gas production （GP） procedure. Fermentation at 24 h （GP 24）, short-chain volatile fatty acids （SCFA）, and microbial crude protein production （mCP）, in vitro organic matter digestibility （OmD）, metabolizable energy （mE） and dry matter degradability （DmD） were estimated. Forage samples were incubated for 72 h in an incubator at 39oC and the volume of GP was recorded at 2, 4, 6, 8, 10, 12, 24, 48, and 72 h of incubation using the reading pressure technique. The rumen fermentation profiles were highest for P. persica, which showed the highest （P〈0.0001） DmD, mE, OmD, SCFA, GP 24 and mCP. On the other hand L. esculenta had the lowest （P〈0.0001） DmD, SCFA, mCP; P. domestica had the lowest （P〈0.0001） OmD. The addition of m to silage increased （P〈0.0001） mE and OmD, as well as GP. However, the addition of U and the mixture of U and m reduced （P〈0.0001） DmD, mE, OmD, SCFA, GY 24 and mCP. These results show that P. persica has the highest nutritive value and L. esculenta the lowest for ruminants. Additionally, the addition of m to forage from fodder trees increases rumen GP and fermentation, which may improve nutrient utilization in ruminants.

关键词： fodder trees urea molasses gas production

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Common coupled fixed point theorem for two pairs compatible and sub-sequentially continuous mapping

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Journal of Ocean Engineering and Science 2024年第4期9卷 401-407页

作者： H.m.Abu-Donia mona S.Bakry H.A.Atia Omnia m.A.Khater Raghda A.m.Attia Department of mathematics Faculty of ScienceZagazig UniversityZagazigEgypt Department of mathematics Faculty of ScienceTanta UniversityTantaEgypt Department of Basic Science Zagazig Higher Institute of Engineering and TechnologyZagazigEgypt Department of Basic Science Higher Technological Institute 10th of Ramadan CityEl Sharqia 44634Egypt

This study establishes a common coupled fixed point for two pairs of compatible and sequentially continuous mappings in the intuitionistic fuzzy metric space that satisfy theφ-contractive *** basic definitions and theorems have been used from some recent scientific papers about the binary operator,t-norm,t-conorm,intuitionistic fuzzy metric space,and compatible mapping for reaching to the paper’s purpose.

关键词： Intuitionistic fuzzy metric space φ-contractive mapping Compatible mappings Couple fixed point

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