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Palliative care service in patients with childhood cancer from a tertiary pediatric oncology center

Pediatric Investigation 2018年第4期2卷 209-215页

作者： Karin KH Ho Frankie WT Cheng molin ky lin Shirley Wai Vincent Lee Chi-kong Li Department of Paediatrics Prince of Wales HospitalThe Chinese University of Hong KongHong KongChina Children's Cancer Foundation Hong KongChina

Importance: Pediatric palliative care (PPC) has gained great attention in western countries, however data on Hong Kong children receiving PPC are limited. There are gaps in knowledge about the PPC needs in local children with cancer. Objective: To assess the current situation of PPC service of Hong Kong children with cancer. Methods: We performed a 10-year retrospective review in a tertiary pediatric oncology unit and studied the referral pattern, clinical characteristics and services provided. results: Totally 117 children were referred to PPC Team which constituted 65% deceased children within the study period. The commonest diagnoses were central nervous system tumour (32.5%), leukaemia (25.6%) and neuroblastoma (9.4%). Ninety-one percent of children were referred after the last relapse or stopping curative treatment. The median time of referral to death was 77 days (interquartile range (IQR): 35, 182)The median number of hospital admission after referral was 2 (IQR: 1, 5), with a median of 27 days total hospital stay (IQR: 10, 60). The reasons for admission were palliative chemotherapy (16.1%), pain control (12.1%) and platelet transfusion (11.2%). For the death episode, the median duration of hospital stay was 15 days (IQR: 2, 46). Most patients received oxygen (82.0%), intravenous fluid (81.2%) and intravenous analgesic (52.1%). A total of 111 (94.9%) children died in hospital, 15 had been admitted into intensive care unit (ICU) but only 5 (4.5%) died in ICU. Interpretation: Pain control and platelet transfusion were common reasons of readmission. Death in ICU and at home was uncommon in Hong Kong situation.

关键词： Cancer Children Palliative care Chinese

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A NOTE ON H-w^p-BOUNDEDNESS OF RIESZ TRANSFORMS AND θ-CALDERóN-ZYGMUND OPERATORS THROUGH MOLECULAR CHARACTERIZATION

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Analysis in Theory and Applications 2011年第3期27卷 251-264页

作者： Luong Dang ky University of Orleans

Let 0 〈 p ≤ 1 and w in the Muckenhoupt class A1. Recently, by using the weighted atomic decomposition and molecular characterization, Lee, lin and yang[11] established that the Riesz transforms R j, j = 1,2,..., n, are bounded on Hwp （Rn）. In this note we extend this to the general case of weight w in the Muckenhoupt class A.. through molecular characterization. One difficulty, which has not been taken care in [11] consists in passing from atoms to all functions in HwP（Rn）. Furthermore, the HwP-boundedness of θ- Calderon-Zygmund operators are also given through molecular characterization and atomic decomposition.

关键词： Muckenhoupt weight Riesz transform Calderon-Zygmund operator

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On the Uniqueness of Heat Flow of Harmonic Maps and Hydrodynamic Flow of Nematic Liquid Crystals

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Chinese Annals of Mathematics,Series B 2010年第6期31卷 921-938页

作者： Fanghua lin Changyou WANG Courant Institute of Mathematical Sciences New York University New York NY 10012 USA Department of Mathematics University of Kentucky Lexington KY 40506 USA.

For any n-dimensional compact Riemannian manifold (M,g) without boundary and another compact Riemannian manifold (N,h), the authors establish the uniqueness of the heat flow of harmonic maps from M to N in the class C([0,T),W1,n). For the hydrodynamic flow (u,d) of nematic liquid crystals in dimensions n = 2 or 3, it is shown that the uniqueness holds for the class of weak solutions provided either (i) for n = 2, u ∈ Lt∞ L2x∩L2tHx1, ▽P∈ Lt4/3 Lx4/3 , and ▽d∈ L∞t Lx2∩Lt2Hx2; or (ii) for n = 3, u ∈ Lt∞ Lx2∩L2tHx1∩ C([0,T),Ln), P ∈ Ltn/2 Lxn/2 , and ▽d∈ L2tLx2 ∩ C([0,T),Ln). This answers affirmatively the uniqueness question posed by lin-lin-Wang. The proofs are very elementary.

关键词： Hydrodynamic flow Harmonic maps Nematic liquid crystals Uniqueness

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An ANN-exhaustive-listing method for optimization of multiple building shapes and envelope properties with maximum thermal performance

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Frontiers in Energy 2021年第2期15卷 550-563页

作者： Yaolin lin Wei YANG School of Mechanical and Automotive Engineering Shanghai University of Engineering ScienceShanghai 201620China School of Civil Engineering and Architecture Wuhan University of TechnologyWuhan 430070China College of Engineering and Science Victoria UniversityMelbourne 8001Australia

With increasing awareness of sustainability, demands on optimized design of building shapes with a view to maximize its thermal performance have become stronger. Current research focuses more on building envelopes than shapes, and thermal comfort of building occupants has not been considered in maximizing thermal performance in building shape optimization. This paper attempts to develop an innovative ANN (artificial neural network)-exhaustive-listing method to optimize the building shapes and envelope physical properties in achieving maximum thermal performance as measured by both thermal load and comfort hour. After verified, the developed method is applied to four different building shapes in five different climate zones in China. It is found that the building shape needs to be treated separately to achieve sufficient accuracy of prediction of thermal performance and that the ANN is an accurate technique to develop models of discomfort hour with errors of less than 1.5%. It is also found that the optimal solutions favor the smallest window-to-external surface area with triple-layer low-E windows and insulation thickness of greater than 90 mm. The merit of the developed method is that it can rapidly reach the optimal solutions for most types of building shapes with more than two objective functions and large number of design variables.

关键词： ANN(artificial neural network) exhaustive-listing building shape optimization thermal load thermal comfort

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垂向环流作用下湖泊沉积物磷迁移行为

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中国环境科学 2021年第6期41卷 2843-2852页

作者：刘园园褚克坚陆滢华祖林 ky Sereyvatanak 顾莉刘晓东徐龙龙河海大学浅水湖泊综合治理与资源开发教育部重点实验室江苏南京210098 河海大学环境学院江苏南京210098 华设设计集团股份有限公司江苏南京210014

以巢湖十五里河入湖河口原位底泥为研究对象,通过室内模型实验,模拟了垂向环流的动水条件下,溶解态无机磷(DIP)在泥水界面的释放-吸附过程,探讨了不同强度环流对河口底泥DIP迁移的影响行为.结果表明:垂向环流扰动会引起上覆水中溶解氧(... 详细信息

以巢湖十五里河入湖河口原位底泥为研究对象,通过室内模型实验,模拟了垂向环流的动水条件下,溶解态无机磷(DIP)在泥水界面的释放-吸附过程,探讨了不同强度环流对河口底泥DIP迁移的影响行为.结果表明:垂向环流扰动会引起上覆水中溶解氧(DO)和悬浮颗粒物(SPM)含量明显上升,且其平衡浓度与扰动强度均呈正相关,但悬浮物中值粒径(D_(50))则随扰动强度的增大而降低;垂向环流作用下沉积物DIP的释放量随时间呈“Λ”型分布,显著区别于其他动水扰动情形,释放峰值与环流强度成显著正相关(P=0.047<0.05),但平衡值则与之呈显著负相关(P=0.034<0.05);环流扰动的增强促进了DIP在沉积物上的吸附,并构建了耦合天然水动力效应的沉积物DIP Freundlich等温吸附经验公式:lgQe=2.7074e^(1.3487τ)+0.9463e^(-1.4830τ)lgCe.

关键词：垂向环流浅水湖泊沉积物 DIP 释放吸附

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Chromium phytoextraction and physiological responses of the hyperaccumulator Leersia hexandra Swartz to plant growth-promoting rhizobacterium inoculation

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Frontiers of Environmental Science & Engineering 2023年第1期17卷 99-110页

作者： Xuehong Zhang Yuanyuan Zhang Dan Zhu Zhiyi lin Na Sun Chang Su Hua lin Junjian Zheng College of Life and Environmental Science Guilin University of Electronic TechnologyGuilin 541004China College of Environmental Science and Engineering Guilin University of TechnologyGuilin 541004China College of Mathematics and Science Wuhan Institute of TechnologyWuhan 430205China

Phytoextraction is a promising option for purifying hexavalent chromium(Cr(Ⅵ))-laden wastewater,but the long remediation period incurred by poor growth rate of Cr hyperaccumulators remains a primary hindrance to its large-scale *** this study,we performed a hydroponic experiment to evaluate the feasibility of promoting the growth and phytoextraction efficiency of Cr hyperaccumulator Leersia hexandra Swartz(***)by inoculating plant growth-promoting rhizobacteria(PGPR)Bacillus cereus(***).In batch tests,the Cr(Ⅵ)removal rates of *** and *** co-culture were greater than the sum of their respective *** was likely due to the microbial reduction of Cr(Ⅵ)to Cr(Ⅲ),which is amiable to plant ***,the PGPR factors of ***,including indoleacetic acid(IAA)production,1-aminocyclopropane-1-carboxylic acid deamination(ACCd)activity,phosphate solubilization capacity,and siderophore production,were *** PGPR factors helped explain the biomass augmentation,root elongation and enhanced Cr enrichment of the inoculated *** in pot *** the increased Cr uptake,no aggravated oxidative damage to the cell membrane was observed in the inoculated *** was attributed to its capacity to confront the increased intracellular Cr stress by upregulating both the activities of antioxidative enzymes and expression of metal-binding proteins/***,*** could always conserve the majority of Cr in the residual and oxalic integrated forms with low mobility and phytotoxicity,irrespective of the *** *** results highlight the constructed Cr hyperaccumulatorrhizobacteria consortia as an effective candidate for decontaminating Cr(Ⅵ)-laden wastewater.

关键词： Hexavalent chromium Hyperaccumulator Rhizobacteria Leersia hexandra Swartz Bacillus cereus Consortia

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Analysis of influencing factors and interaction of body weight and disease outcome in patients with prediabetes

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World Journal of Diabetes 2023年第10期14卷 1551-1561页

作者： Yan-Yan Li lin-Ping Tong Xian-Dan Wu Dan lin Yue lin Xiao-Yang lin Department of General Practice The First People’s Hospital of Wenling CityWenling 317500Zhejiang ProvinceChina Department of Oncology Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese MedicineShanghai 200437China Department of General Medicine The First People’s Hospital of Wenling CityWenling 317500Zhejiang ProvinceChina

BACKGROUND The trend of prediabetes progressing to type 2 diabetes mellitus(T2DM)is prominent,and effective intervention can lead to a return to *** the factors influencing the outcome of prediabetes is helpful to guide clinical *** weight change in patients with prediabetes has not attracted much *** To explore the interaction between body weight and the factors affecting the progression of prediabetes to *** We performed a retrospective analysis of 236 patients with prediabetes and 50 with normal glucose tolerance(NGT),and collected clinical data and follow-up results of all *** on natural blood glucose outcomes,we classified 66 patients with progression to T2DM into the disease progression(DP)group,and 170 patients without progression to T2DM into the disease outcome(DO)*** analyzed the factors that influenced prediabetes outcome and the influence of body weight on prediabetes blood glucose outcome by unconditional logistic regression.A general linear model(univariate)was used to analyze the interaction between body weight and independent influencing *** There were 98 cases of impaired fasting glucose(IFG),90 cases of impaired glucose tolerance(IGT),and 48 cases of coexistent IFG and *** body weight,waist circumference,body mass index,fasting blood glucose,and 2 h plasma glucose of patients with IFG,IGT,and coexistent IFG and IGT were higher than those in patients with NGT(Plin,and homeostatic model assessment for insulin resistance were independent factors affecting progression of prediabetes to T2DM(P<0.05).Receiver operating characteristic curve analysis showed that the area under the curve predicted by the above indicators combined was 0.905[95%confidence interval(CI):0.863-0.948],which was greater than that predicted by each indicator *** regression analysis with

关键词： Prediabetes Type 2 diabetes mellitus Body weight Disease outcome Influencing factors Interactions Lowcarbohydrate diet

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Non-noble metal-based catalysts for acetylene semihydrogenation:from thermocatalysis to sustainable catalysis

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Science China Chemistry 2023年第7期66卷 1963-1974页

作者： Lei Zhang Jin lin Zhenpeng Liu Jian Zhang Research&Development Institute of Northwestern Polytechnical University in Shenzhen School of Chemistry and Chemical EngineeringNorthwestern Polytechnical UniversityXi’an 710129China State Key Laboratory of Solidification Processing and School of Materials Science and Engineering Northwestern Polytechnical UniversityXi’an 710072China

Selective semihydrogenation of acetylene in raw olefin streams to ethylene is a key industrial reaction to produce polymer-grade feeds for the manufacture of corresponding *** currently used process in industry is the thermocatalytic acetylene semihydrogenation with pressurized hydrogen and Pd-based catalysts at relatively high *** high cost of Pd urgently desires the design of non-noble metal-based ***,non-noble metal-based catalysts commonly require much higher reaction temperatures than Pd-based catalysts because of their poor intrinsic ***,aiming at increasing economic efficiency and sustainability,various strategies are explored for developing non-noble metal-based catalysts for thermocatalytic and green acetylene semihydrogenation *** this review,we systematically summarize the recent advances in catalytic technology from thermocatalysis to sustainable alternatives,as well as corresponding regulation strategies for designing high-performance non-noble metal-based *** crucial factors affecting catalytic performance are discussed,and the fundamental structure-performance correlation of catalysts is ***,we emphasize current challenging issues and future perspectives for acetylene *** review will not only promote the rapid exploration of non-noble metal-based catalysts for acetylene semihydrogenation,but also advance the development of sustainable processes like electrocatalysis and photocatalysis.

关键词： acetylene semihydrogenation non-noble metal-based catalysts thermocatalysis sustainable catalysis

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Clustering-triggered Emission of Cellulose and Its Derivatives

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Chinese Journal of Polymer Science 2019年第4期37卷 409-415,I0007页

作者： lin-lin Du Bing-Li Jiang Xiao-Hong Chen Yun-Zhong Wang lin-Min Zou Yuan-Li Liu Yong-Yang Gong Chun Wei Wang-Zhang Yuan Key Laboratory of New Processing Technology for Non-ferrous Metals and Materials Ministry of EducationCollege of Materials Science and EngineeringGuilin University of Technology College of Pharmacy Guilin Medical University School of Chemistry and Chemical Engineering Shanghai Jiao Tong University

In recent years, nonconventional luminogens free of aromatic groups have attracted extensive attention due to their academic importance and promising wide applications. Whilst previous studies generally focused on fluorescence from aliphatic amine or carbonylcontaining systems, less attention has been paid to room temperature phosphorescence(RTP) and the systems with predominant oxygen functionalities. In this work, photophysical properties of the polyhydroxy polymers, including microcrystalline cellulose(MCC), 2-hydroxyethyl cellulose(HEC), hydroxypropyl cellulose(HPC), and cellulose acetate(CA), were studied and compared. While MCC,HEC, and HPC solids showed bright emission alongside distinct RTP, CA demonstrated relatively low intensity of solid emission without noticeable RTP. Their emissions were explained in terms of the clustering-triggered emission(CTE) mechanism and conformation rigidification. Additionally, on account of its intrinsic emission, concentrated HEC aqueous solution could be used as the probe for the detection of 2,4,6-trinitrophenol(TNP).

关键词： Cellulose Nonconventional luminogens Room temperature phosphorescent Clustering-triggered emission

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Reliability Analysis for Complex Systems Based on Dynamic Evidential Network Considering Epistemic Uncertainty

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Computer Modeling in Engineering & Sciences 2017年第1期113卷 17-34页

作者： Rongxing Duan Yanni lin Longfei Hu School of Information Engineering Nanchang UniversityNanchangChina

Fault tolerant technology has greatly improved the reliability of modern systems on one hand and makes their failure mechanisms more complex on the *** characteristics of dynamics of failure,diversity of distribution and epistemic uncertainty always exist in these systems,which increase the challenges in the reliability assessment of these systems *** paper presents a novel reliability analysis framework for complex systems within which the failure rates of components are expressed in interval ***,it uses a dynamic fault tree(DFT)to model the dynamic fault behaviors and copes with the epistemic uncertainty using Dempster-Shafer(D-S)theory and interval ***,an approach is presented to convert a DFT into a dynamic evidential network(DEN)to calculate the reliability ***,a sorting method based on the possibility degree is proposed to rank the importance of components represented by interval numbers in order to obtain the most critical components,which can be used to provide the guidance for system design,maintenance planning and fault ***,a numerical example is provided to illustrate the availability and efficiency of the proposed method.

关键词： Reliability analysis dynamic fault tree interval numbers dynamic evidential network epistemic uncertainty

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