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Hodgkin lymphoma masquerading as perforated gallbladder adenocarcinoma:A case report

World Journal of Gastrointestinal Surgery 2021年第10期13卷 1279-1284页

作者： Michelle Manesh reynold Henry Shea Gallagher Michael Greas mohd r.ashid sheikh Shannon Zielsdorf Department of Surgery University of Southern CaliforniaLos AngelesCA 90033United States Department of Pathology University of Southern CaliforniaLos AngelesCA 90033United States

BACKGrOUND There are several case reports of acute cholecystitis as the initial presentation of lymphoma of the gallbladder;all reports describe non-Hodgkin lymphoma or its subtypes on histopathology of the gallbladder tissue ***,there is no description in the literature of Hodgkin lymphoma causing hilar lymphadenopathy,inevitably presenting as ruptured cholecystitis with imaging mimicking gallbladder *** SUMMArY A 48-year-old man with a past medical history of diabetes mellitus presented with progressive abdominal pain,jaundice,night sweats,weakness,and unintended weight loss for one ***-up revealed a mass in the region of the porta hepatis causing obstructions of the cystic and common hepatic ducts,gallbladder rupture,as well as retroperitoneal *** clinical picture and imaging findings were suspicious for locally advanced gallbladder adenocarcinoma causing ruptured cholecystitis and cholangitis,with metastases to retroperitoneal lymph *** invasive techniques,including endoscopic duct brushings and percutaneous lymph node biopsy,were inadequate for tissue ***,this case required exploratory laparo-tomy,open cholecystectomy,and periaortic lymph node dissection for histopathological assessment and definitive *** lymphoma was present in the lymph nodes while the gallbladder specimen had no evidence of *** This clinical scenario highlights the importance of histopathological assessment in diagnosing gallbladder malignancy in a patient with gallbladder perforation and a grossly positive positron emission tomography/computed tomography *** both gallbladder adenocarcinoma and Hodgkin lymphoma,medical and surgical therapies must be tailored to the specific disease entity in order to achieve optimal long-term survival rates.

关键词： Hodgkin lymphoma Gallbladder perforation Acute cholecystitis Gallbladder adenocarcinoma Case report

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Unraveling the therapeutic mechanisms of myristic acid and luteolin 7-rutinoside in oral cancer: insights from network pharmacology and molecular docking analysis

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Pharmacology Discovery 2024年第2期4卷 1-9页

作者： Ansari Vikhar Danish Ahmad Misba ruhi Syed Ayaz Ali Qazi Yasar mohd.Mukhtar Khan Subur W Khan Mohammed Imran Anees Y.B.Chavan College of Pharmacy Dr.Babasaheb Ambedkar Marathwada UniversityAurangabad 431001India Maulana Azad College Dr.Babasaheb Ambedkar Marathwada UniversityAurangabad 431001India

Background:The compound Luteolin-7-rutinoside(L7r)is a flavone derivative of luteolin,predominantly identified in plant species belonging to the families ***,Myristic acid is characterized by its structure as a 14-carbon,unsaturated fatty *** this investigation,we endeavor to elucidate the putative mechanisms underlying the therapeutic effects of Myristic Acid and Luteolin 7-rutinoside in the context of oral cancer treatment,employing network pharmacology coupled with molecular docking ***:The protein targets of Myristic Acid and Luteolin 7-rutinoside were identified through a search on the Swiss Target ***,a compound-target network was constructed using Cytoscape *** associated with OC were retrieved from the OMIM and GeneCards *** overlap between compound targets and OC-related targets was determined,and the resulting shared targets were subjected to protein-protein interaction(PPI)network analysis using the STrING ***,gene ontology(GO)and Kyoto Encyclopedia of Genes and Genomes(KEGG)enrichment analyses were conducted on the identified *** docking were performed to investigate the interactions between the core target and the active ***:The component target network comprises 103 nodes and 102 *** the proteins in the protein-protein interaction(PPI)network,those with higher degrees are TNF,PPArG,and *** through Gene Ontology(GO)and Kyoto Encyclopedia of Genes and Genomes(KEGG)pathways indicates that the treatment of OC with Myristic Acid and Luteolin 7-rutinoside primarily involves the regulation of mirNA transcription and inflammatory *** identified signaling pathways include Pathways in cancer,PPAr signaling pathway,EGFr signaling pathway,and TNF signaling *** docking studies reveal that Luteolin 7-rutinoside and Myristic acid exhibit higher affinity towards TNF,PPArG,TP53,and ***:This study

关键词： myristic acid luteolin 7-rutinoside network pharmacology oral cancer molecular docking

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Synthesis of Hierarchical SnO2 Nanowire–TiO2 Nanorod Brushes Anchored to Commercially Available FTO-coated Glass Substrates

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Nano-Micro Letters 2017年第3期9卷 93-100页

作者： Derek r.Miller sheikh A.Akbar Pat A.Morris Department of Materials Science and Engineering The Ohio State UniversityColumbusOH 43212USA

Growth of single-crystal Sn O_2 nanowires using a fluorine-doped Sn O_2(FTO) thin film as both the source and substrate is demonstrated for the first time at relatively low temperature(580 °C) which preserves the integrity of the underlying glass support and improves scalability to devices. Furthermore, a microwave hydrothermal process is shown to grow Ti O_2 nanorods on these nanowires to create a hierarchical nanoheterostructure that will lead to efficient photogenerated charge carrier separation and rapid transport of electrons to the substrate. This process simplifies nanowire growth by using commercially available and widely used FTO substrates without the need for an additional upstream Sn source and can be used as a high surface area host structure to many other hierarchical structures.

关键词： SnO2 Nanowire Fluorine-doped SnO2(FTO) Vapor–liquid–solid(VLS) TiO2 Nanorod brush

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Unusual presentations of eosinophilic gastroenteritis:Case series and review of literature

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World Journal of Gastroenterology 2009年第17期15卷 2156-2161页

作者： rafiq A sheikh Thomas P Prindiville r Erick Pecha Boris H ruebner Department of Gastroenterology Kaiser Permanente Medical Center 6600 Bruceville Road SacramentoCA 95823 United States Department of Gastroenterology University of California Davis 4150 V Street Sacramento CA95917 United States Department of Gastroenterology Marshall Medical Center 1100 Marshall Way Placerville CA 95667 United States Department of Pathology University of California Davis 4150 V Street Sacramento CA 95917 United States

Eosinophilic gastroenteritis (EG) is an uncommon disease characterized by focal or diffuse eosinophilic infiltration of the gastrointestinal tract, and is usually associated with dyspepsia, diarrhea and peripheral eosinophilia. Diffuse gastrointestinal tract and colonic involvement are uncommon. The endoscopic appearance may vary from normal to mucosal nodularity and ulceration. Gastrointestinal obstruction is unusual and is associated with predominantly muscular disease. We present five unusual cases of EG associated with gastric outlet and duodenal obstruction. Two cases presented with acute pancreatitis and one had a history of pancreatitis. Four cases responded well to medical therapy and one had recurrent gastric outlet obstruction that required surgery. Four out of the five cases had endoscopic and histological evidence of esophagitis and two had colitis. Two patients had ascites. These cases reaffirm that EG is a disorder with protean manifestations and may involve the entire gastrointestinal tract. Gastric outlet and/or small bowel obstruction is an important though uncommon presentation of EG. It may also present as esophagitis, gastritis with polypoid lesions, ulcers or erosions, colitis and pancreatitis and may mimic malignancy.

关键词： Gastroenteritis Eosinophilic Gastrointestinal obstruction Eosinophilic esophagitis Eosinophilic colitis Eosinophilic pancreatitis

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A kinetic approach to evaluate salinity effects on carbon mineralization in a plant residue-amended soil

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2006年第10期7卷 788-793页

作者： NOUrBAKHSH Farshid sheikh-HOSSEINI Ahmad r. Department of Soil Science School of Agriculture Isfahan University of Technology Isfahan 84154 Iran

The interaction of salinity stress and plant residue quality on C mineralization kinetics in soil is not well understood. A laboratory experiment was conducted to study the effects of salinity stress on C mineralization kinetics in a soil amended with alfalfa, wheat and corn residues. A factorial combination of two salinity levels （0.97 and 18.2 dS/m） and four levels of plant residues （control, alfalfa, wheat and corn） with three replications was performed. A first order kinetic model was used to describe the C mineralization and to calculate the potentially mineralizable C. The CO2-C evolved under non-saline condition, ranged from 814.6 to 4842.4 mg CO2-C/kg in control and alfalfa residue-amended soils, respectively. Salinization reduced the rates of CO2 evolution by 18.7%, 6.2% and 5.2% in alfalfa, wheat and corn residue-amended soils, respectively. Potentially mineralizable C （Co） was reduced significantly in salinized alfalfa residue-treated soils whereas, no significant difference was observed for control treatments as well as wheat and corn residue-treated soils. We concluded that the response pattern of C mineralization to salinity stress depended on the plant residue quality and duration of incubation.

关键词： Salinity stress Carbon mineralization First-order kinetics Plant residues residue quality

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DNNBoT: Deep Neural Network-Based Botnet Detection and Classification

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Computers, Materials & Continua 2022年第4期71卷 1729-1750页

作者： mohd Anul Haq mohd Abdul rahim Khan Department of Computer Science College of Computer and Information SciencesMajmaah UniversityAl-Majmaah 11952Saudi Arabia

The evolution and expansion of IoT devices reduced human efforts,increased resource utilization, and saved time;however, IoT devices createsignificant challenges such as lack of security and privacy, making them morevulnerable to IoT-based botnet attacks. There is a need to develop efficientand faster models which can work in real-time with efficiency and stability. The present investigation developed two novels, Deep Neural Network(DNN) models, DNNBoT1 and DNNBoT2, to detect and classify well-knownIoT botnet attacks such as Mirai and BASHLITE from nine compromisedindustrial-grade IoT devices. The utilization of PCA was made to featureextraction and improve effectual and accurate Botnet classification in IoTenvironments. The models were designed based on rigorous hyperparameterstuning with GridsearchCV. Early stopping was utilized to avoid the effects ofoverfitting and underfitting for both DNN models. The in-depth assessmentand evaluation of the developed models demonstrated that accuracy andefficiency are some of the best-performed models. The novelty of the presentinvestigation, with developed models, bridge the gaps by using a real datasetwith high accuracy and a significantly lower false alarm rate. The results wereevaluated based on earlier studies and deemed efficient at detecting botnetattacks using the real dataset.

关键词： Botnet network monitoring machine learning deep neural network IoT threat

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Massive MIMO system lower bound spectral efficiency analysis with precoding and perfect CSI

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Digital Communications and Networks 2021年第3期7卷 342-351页

作者： Tasher Ali sheikh Joyatri Bora Md Anwar Hussain Department of Electronics and Communication Engineering North Eastern Regional Institute of Science and TechnologyNirjuliArunachal Pradesh791109India

The analytical lower bound of Spectral Efficiency(SE)of downlink transmission of the Massive Multiple Input Multiple Output(Ma-MIMO)system is *** this paper,we derive some novel and approximate mathematical expressions for the lower bound of the SE of a Ma-MIMO with linear precoding schemes,i.e.,Minimum Mean Square Error(MMSE)and Zero-Forcing(ZF).For simulation analysis of the SE,we consider three joint users and antenna scheduling algorithms,namely,the semi-orthogonal,random,and distance-based user scheduling algorithms,whereas the antennas are selected based on Maximum Signal to Noise ratio(MSNr)with scheduled *** channel between the user and the transmitter is assumed to have characteristics of Small Scale Fading(SSF)and Large Scale Fading(LSF)with the rayleigh fading *** investigate the effect of the variation of transmitting SNr,the number of base station antennas(M),and the radius(r)of the cell area on the *** simulate the downlink transmission of Ma-MIMO and compare the simulation and analytical *** is observed that the trends of variation of both results are similar to the variation of identical factors,and the difference between the simulated and analytical lower bounds of the SE is approximately 1-1.5 *** analytical lower bound is smaller than the simulation result.

关键词： Fifth-generation Spectral efficiency Ma-MIMO LSF coefficient Precoding

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Structural, vibrational, optical, photoluminescence, thermal,dielectric, and mechanical studies on zinc(tris) thiourea sulfate single crystal: A noticeable effect of organic dye

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Chinese Physics B 2018年第5期27卷 304-312页

作者： mohd Shkir V Ganesh S AlFaify I S Yahia mohd Anis Advanced Functional Materials & Optoelectronic Laboratory Department of PhysicsFaculty of ScienceKing Khalid University Department of Physics Sant Gadge Baba Amravati University

In this work, uranine-dyed zinc（tris） thiourea sulfate（ZTS） monocrystals, 26 mm×15 mm×10 mm in size, were synthesized by the solution method at ambient temperature. Their purity, crystallinity, lattice parameters, and functional modes were studied by x-ray diffraction, Fourier transform-infrared spectroscopy（FT-Ir）, and FT-raman spectroscopy analyses. The sodium ion content of the crystals from the dye was confirmed by elemental analysis. The diffused reflectance spectral analysis of the dyed crystal revealed a characteristic absorption band at 490 nm attributed to the presence of the dye. The calculated band gaps of the non-dyed and dyed crystals were 4.53 and 4.57 e V, respectively. A green emission peak at ～（512 ± 4） nm was observed in the photoluminescence spectrum of the uranine-dyed crystals. A differential scanning calorimetry study confirmed that the thermal stability improved owing to the addition of the dye. Dielectric and microhardness studies were conducted to examine the significant improvements in the corresponding properties of dyed crystals. The results demonstrated the competency of the dyed ZTS crystals for applications in optoelectronic devices.

关键词： crystal growth dielectric properties luminescence thermal properties mechanical properties

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CDLSTM: A Novel Model for Climate Change Forecasting

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Computers, Materials & Continua 2022年第5期71卷 2363-2381页

作者： mohd Anul Haq Department of Computer Science College of Computer and Information SciencesMajmaah UniversityAL Majmaah11952Saudi Arabia

Water received in rainfall is a crucial natural resource for agriculture,the hydrological cycle,and municipal *** changing rainfall pattern is an essential aspect of assessing the impact of climate change on water resources planning and *** change affected the entire world,specifically India’s fragile Himalayan mountain region,which has high significance due to being a climatic *** water coming from Himalayan rivers is essential for 1.4 billion people living *** studies either modeled temperature or rainfall for the Himalayan area;however,the combined influence of both in a long-term analysis was not performed utilizing Deep Learning(DL).The present investigation attempted to analyze the time series and correlation of temperature(1796–2013)and rainfall changes(1901–2015)over the Himalayan states in *** Climate Deep Long Short-Term Memory(CDLSTM)model was developed and optimized to forecast all Himalayan states’temperature and rainfall ***’s Prophet(FB-Prophet)model was implemented to forecast and assess the performance of the developed CDLSTM *** performance of both models was assessed based on various performance metrics and shown significantly higher accuracies and low error rates.

关键词： Himalayas climate change cdlstm facebook temperature rainfall

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Advances in reduction of NO_x and N_2O emission formation in an oxy-fired fluidized bed boiler

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Chinese Journal of Chemical Engineering 2019年第2期27卷 426-443页

作者： Khalid El sheikh Mohammad Jakir Hossain Khan Mahar Diana Hamid Siddhartha Shrestha Brahim Si Ali G.A.ryabov Lya A.Dolgushin mohd Azlan Hussain Tatiana V.Bukharkina Elena A.Gorelova Dmitry Mendeleev University of Chemical Technology of russia Department of Chemical Engineering Faculty of Engineering University of Malaya Laboratory for Simulation and Modelling of Particulate Systems Department of Chemical Engineering Monash University All-russian Thermal Engineering Institute VTI

Fossil fuel combustion is one of the major means to meet the mounting global energy demand. However, the increasing NO_x and N_2 O emissions arising from fossil fuel combustion process have hazardous effects. Thus, mitigating these gases is vital to attain a sustainable environment. Interestingly, oxy-fuel combustion in fluidized bed for carbon capture and minimized NO_x emissions is strongly sustainable compare to the other approaches. It was assessed that NO_x formation and fuel-N conversion have significant limitation under oxy-fluidized bed compared to air mode and the mechanism of NO_x formation is still deficient and requires further development. In addition, this review paper discussed the potential of primary measure as low emission process with others supplementary techniques for feasible NO_x reduction. The influences of combustion mode, operating parameters, and reduction techniques such as flue gas recirculation, oxygen staging, biomass co-firing, catalyst, influence of fluidized bed design and structure, decoupling combustion and their merges are respectively evaluated. Findings show that significant minimization of NO_x emission can be achieved through combination of primary and secondary reduction techniques.

关键词： Oxy-fuel combustion Fluidized bed technology Biomass blend Primary/secondary measures NOx emission

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