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Anti-cancer potential of South Asian plants

Natural Products and Bioprospecting 2013年第3期3卷 74-88页

作者： mohammad Mijanur rahman Md.Asaduzzaman KHAN Department of Biochemistry and Molecular Biology Jahangirnagar UniversitySavarDhaka 1342Bangladesh Department of Biochemistry School of Life SciencesCentral South UniversityChangsha 410013China

Phyto-chemicals are increasingly being used in the treatment of cancer because of their availability,potential anti-cancer activity with less adverse effects when compared with *** variation of climate and geography in South Asian countries provides a nursing environment for the growth of versatile plant species,that are repeatedly drawing attention of the scientific *** this review,we have focused on the anti-cancer potential of thirty plants,which are commonly found in Bangladesh,India,Nepal,Pakistan and Sri Lanka,with their mechanisms of *** particular,we have discussed the bio-active components that display anti-cancer activity,which have been identified in these *** review may help researchers to profile plants with known anti-cancer effect of this region and further investigations of anti-cancer agents in medicinal plants from South Asia.

关键词： natural products South Asia medicinal plants anti-cancer activities phyto-chemicals

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Influence of soil physicochemical properties,particle size fractions and mineralogy on the leaching potentials of arsenic and antimony in abandoned mine soils

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Pedosphere 2023年第5期33卷 744-753页

作者： A.S.M.Fazle BARI Dane LAMB Geoff R.MACFARLANE mohammad Mahmudur rahman Global Centre for Environmental Remediation(GCER) College of EngineeringScience and EnvironmentThe University of NewcastleCallaghanNSW 2308Australia Department of Soil Science Sher-e-Bangla Agricultural UniversityDhaka 1207Bangladesh Chemical and Environmental Engineering School of EngineeringRMIT UniversityMelbourneVictoria 3000Australia School of Environmental and Life Sciences The University of NewcastleCallaghanNSW 2308Australia

At abandoned mine sites,arsenic(As)-and antimony(Sb)-enriched soils are often disposed of through onsite burial or *** highly weathered mine sites,the mobility of As and Sb is typically controlled by iron(Fe)(III)/Fe(II)phases;thus,the suitability of such disposal methods and appropriate testing techniques are *** the present study,leaching potentials of As and Sb were examined using the toxicity characteristic leaching procedure(TCLP),waste extraction test(WET),and WET-extended procedure(WET-EXT)at three abandoned mine site soils in *** leached concentration of As regularly exceeded USEPA criteria(5 mg L^(-1)).The highest leached concentrations of As and Sb were observed in the finest particle size fraction(<0.053 mm)by WET-EXT(1040 mg L^(-1)for As and 21.10 mg L^(-1)for Sb)followed by WET(800 mg L^(-1)for As and 20.90 mg L^(-1)for Sb).The TCLP method resulted in the lowest concentrations of leached As(0.0009 mg L^(-1))and Sb(0.0003 mg L^(-1)).Crystalline and amorphous As-bearing Fe oxides were the main phases in the soils ***,the best correlations of leached As determined by TCLP(0.832),WET(0.944),and WET-EXT(0.961)were found with the non-specifically sorbed(NS1)As *** mineralogical and sequential extraction data clearly indicate the dominant role of Fe geochemistry in controlling leachability of As and *** TCLP method was unlikely to be suitable for assessing leachability,as it exhibited no relationship with leachable Fe and substantially lower leached As and Sb than the other two *** the high to extremely high leachable As and Sb concentrations,most of the soil samples would not be recommended for placement in capping works,old shafts,or reduction systems(e.g.,collection in drainage basins).

关键词： particle size fraction sequential extraction toxic element toxicity characteristic leaching procedure waste extraction test

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Effect of Cobalt Doping on the Microstructure and Tensile Properties of Lead Free Solder Joint Subjected to Electromigration

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Journal of Materials Science & Technology 2016年第11期32卷 1129-1136页

作者： M.Nasir Bashir A.S.M.A.Haseeb Abu Zayed mohammad Saliqur rahman M.A.Fazal Department of Mechanical Engineering University of Malaya

Rapid Cu diffusion is one of the main causes of electromigration（EM） failure in lead-free solder *** this study, an effort has been made to investigate the detrimental effects of EM on microstructure and mechanical performance of solder joint by introducing Co nanoparticles（NP） doped flux at the interface between SAC305 solder and copper substrate. EM tests were conducted on un-doped SAC305 and Co-doped SAC305 solder joints for different time intervals, with the maximum duration of 1128 h. A DC current was applied to the both types of solder joints to achieve a current density of 1 × 104A/cm2. EM tests were performed in an oil bath maintained at a constant temperature of 80 °C. It is found that Codoped flux significantly reduced the formation of cracks and voids at the cathode interface. Co atoms entered into the lattice of Cu6Sn5 leading to the formation of（Cu, Co）6Sn5. This thermodynamically stabilized the interfacial intermetallic（IMC） layers both at the anode and cathode sides and suppressed the change in their thickness. The average anodic growth rate of（Cu, Co）6Sn5 interfacial IMC in the doped sample was about one order of magnitude lower compared with that of Cu6Sn5 in the un-doped ***-NP also improved the tensile strength considerably before and after EM. The report suggests that the reliability of solder joint during EM can be improved by using Co-NP doped flux.

关键词： Electromigration damages Tensile strength Intermetallic compounds Nanoparticles Reliability

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Phytopharmacological evaluation of ethanol extract of Sida cordifolia ***

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Asian Pacific Journal of Tropical Biomedicine 2014年第1期4卷 18-24页

作者： mohammad Abdul Motalib Momin Sm Faysal Bellah Sarder mohammad Raussel rahman Ahmed Ayedur rahman Gazi mohammad Monjur Murshid Sarder mohammad Saker Billah Talha Bin Emran Department of Pharmacy Jahangirnagar University Department of Clinical Pharmacy and Pharmacology Dhaka University Pharmacy Discipline Life Science SchoolKhulna University Department of Chemistry Gort.M.M.University College Department of Pharmacy BGC Trust University

Objective:To investigate the phytochemical screening(group determination)and selected pharmacological activities(antioxidant,antimicrobial and analgesic activity)of the plant Sida cordifolia Linn(***).Methods:Eighty percent concentrated ethanol extract of the roots was *** identify the chemical constituents of plant extract standard procedures were *** phytochemical screening the crude extract was tested for the presence of different chemical groups like reducing sugar,tannins,saponins,steroids,flavonoids,gums,alkaloids and *** antioxidant property of ethanolic extract of *** was assessed by DPPH free radical scavenging *** activity of the extract was tested using the model of acetic acid induced writhing in *** sodium is used as reference standard drug for the analgesic activity test Antibacterial activity of plant extract was carried out using disc diffusion method with five pathogenic bacteria comparison with kanamycin as a ***:Phytochemical analysis of the ethanolic extract of the roots of *** indicated the presence of reducing sugar,alkaloids,steroids and *** DPPH scavenging assay the IC_(50)value was found to be 50 ug/mL which was not comparable to the standard ascorbic *** crude extract produced 44.3%inhibition of writhing at the dose of 300 mg/kg body weight which is statistically significant(P>0.001).The in vitro antimicrobial activity of the ethanol extract of the roots of *** showed no antimicrobial activity against five types of *** experiment was conducted only with five species of bacteria as test species,which do not at all indicate the total inactivity against ***:The obtained results provide a support for the use of this plant in traditional medicine but further pharmacological studies are required.

关键词： Antioxidant Antimicrobial Analgesic DPPH Phytochemical screening

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Interaction of tetradecyltrimethylammonium bromide with bovine serum albumin in different compositions: Effect of temperatures and electrolytes/urea

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Chinese Journal of Chemical Engineering 2021年第1期34卷 279-287页

作者： Joynal Abedin ShamimMahbub mohammad Majibur rahman Anamul Hoque Dileep Kumar Javed Masood Khan Ahmed M.El-Sherbeeny Department of Chemistry Jahangirnagar UniversitySavarDhaka 1342Bangladesh Department of Chemistry&Physics Gono BishwabidyalaySavarDhaka 1344Bangladesh Department of Environmental Sciences Jahangirnagar UniversitySavarDhaka 1342Bangladesh 4 Division of Computational Phys ics Institute for Computational ScienceTon Duc Thang UniversityHo Chi Minh CityViet Nam Faculty of Applied Sciences Ton Duc Thang UniversityHo Chi Minh CityViet Nam Department of Food Science and Nutrition Faculty of Food and Agricultural SciencesKing Saud University2460Riyadh 11451Saudi Arabia Industrial Engineering Department College of EngineeringKing Saud UniversityP.O.Box 800Riyadh 11421Saudi Arabia

Herein,the interaction of a protein,bovine serum albumin(BSA),with tetradecyltrimethylammonium bromide(TTAB,a cationic surfactant),has been investigated using the conductivity measurement technique in pure water and some sodium salts(NaCl,Na_(2) SO_(4),Na_(2) CO_(3), and Na_(3) PO_(4)) solutions at temperature range of 295.15-320.15 *** reveal that,in the plot of specific conductivity versus the concentration of TTAB,only a single critical micelle concentration(cmc) was found for the TTAB+BSA mixed system in all solvents media *** addition of BSA in aqueous TTAB solution,the value of cmc undergoes a change from its pure form,which indicates the presence of strong interaction operating between the BSA and TTAB *** aqueous system,the cmc values of the TTAB+BSA mixtures are obtained higher compared to the values found for single TTAB surfactant However,the addition of salt decreases the cmc value of mixed TTAB+BSA *** values of cmc of the BSA+TTAB mixed system at 310.15 K and 1.00 mmol·kg^(-1) ionic strength of salt followed the order:cmc_(Na_(2) CO_(3))> Cmcc_(Na_(3) PO_(4))> cmcNaCl>cMC_(Na_(2) SO_(4)).The cmc values of TTAB+BSA mixture were found to be lowered in urea solution within the concentrations *** values of degree of dissociation(α) and fraction of counter ion binding(β) were found to be dependent on additives and *** free energy of micellization(AGm) is negative for all the systems,which manifests that the micellization phenomenon is energetically *** enhancement of the negative value of △G_(m)^(0) in aqueous salt solutions reveals an increase of spontaneity of the TTAB+BSA micellization *** values of △G_(m)^(0) also reveal that the spontaneity of micelle formation is enhanced at higher temperatures in all media *** values of free energy of transfer(△G_(m,t)^(o)) were also determined for numerous solvent media used in the present study and described with appropriate reasoning.

关键词： TTAB BSA Conductivity Electrolyte Exothermic interaction

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