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Magnesium/Nano-hydroxyapatite Composite for Bone Reconstruction: The Effect of Processing Method

Journal of Bionic Engineering 2020年第1期17卷 92-99页

作者： mohammad Khodaei Farahnaz Nejatidanesh mohammad javad shirani Srinivasan Iyengar Hossein Sina Omid Savabi Department of Materials Science and Engineering Golpayegan University of TechnologyGolpayegan ***Iran Dental Materials Research Center Dental Research InstituteSchool of DentistryIsfahan University of Medical SciencesIsfahan ***Iran Post graduate student of Prosthodontics Student Research CommitteeSchool of DentistryIsfahan University of Medical SciencesIsfahan ***Iran Materials Engineering Division Faculty of EngineeringLund UniversityLund 11822100Sweden European Spallation Source ERIC Lund 17622100Sweden Dental Research Center Dental Research InstituteSchool of DentistryIsfahan University of Medical SciencesIsfahan ***Iran

Nano-ceramic particles can serve as reinforcing agents for metallic materials to improve their mechanical ***,it is important to ensure chemical compatibility between the matrix and *** the present study,magnesium composites with and without nano-hydroxyapatite(nHA)particles were fabricated for bone reconstruction *** different techniques were used,Conventional Sintering(CS)of powder compacts and Spark Plasma Sintering(SPS)of pre-compacted *** showed that a 10 wt%addition of nHA particles to magnesium,followed by SPS improved the compression strength by 27%.CS did not lead to any significant improvement compared to SPS processing.X-ray diffraction data after CS revealed the formation of unfavorable phases due to chemical reactions between nHA particles and the magnesium matrix,while these phases were absent after SPS *** mechanical properties of the specimens fabricated by CS were much inferior to those processed using *** shorter processing time associated with SPS leaded to reduced interaction between nHA particles and the Mg-matrix,compared to CS.

关键词： magnesium nano-hydroxyapatite composite materials in situ reaction biomedical-materials

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Suspended particulate matter promotes epithelial-to-mesenchymal transition in alveolar epithelial cells via TGF-β1-mediated ROS/IL-8/SMAD3 axis

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Journal of Environmental Sciences 2024年第7期141卷 139-150页

作者： Shahrzad Molavinia Dian Dayer mohammad javad Khodayar Gholamreza Goudarzi Maryam Salehcheh Cellular and Molecular Research Center Medical Basic Sciences Research InstituteAhvaz Jundishapur University of Medical SciencesAhvazIran Department of Toxicology School of PharmacyAhvaz Jundishapur University of Medical SciencesAhvazIran Student Research Committee Ahvaz Jundishapur University of Medical SciencesAhvazIran Toxicology Research Center Medical Basic Sciences Research InstituteAhvaz Jundishapur University of Medical SciencesAhvazIran Air Pollution and Respiratory Diseases Research Center Ahvaz Jundishapur University of Medical SciencesAhvazIran Iranian Scientific Association of Clean Air TehranIran

Epidemiological evidence presents that dust storms are related to respiratory diseases,such as pulmonary fibrosis(PF).However,the precise underlying mechanisms of SPM-elicited adverse effects still need to be ***-mesenchymal transition(EMT)process is a characteristic of *** discussed whether suspended particulate matter(SPM)is involved in EMT induction via transforming growth factor-β1(TGF-β1).In this study,a detailed elemental analysis(55 elements),particle size,and morphology were *** investigate the toxicity of SPM,an MTT test was performed to detect cell ***,A549cells were exposed to selected concentrations of SPM(20 and 40μg/mL)for single and repeated *** DCFH-DA assay showed that exposure to SPM could produce reactive oxygen species(ROS).The ELISA assay demonstrated increased levels of interleukin-8(IL-8)and TGF-β1 in the *** blot was used to detect the expression of proteins associated with EMT and the SMAD3-dependent *** of western blot demonstrated that E-cadherin was reduced,whereas p-SMAD3,vimentin,andα-smooth muscle actin were *** findings indicated that SPM triggered EMT by induction of oxidative stress,inflammation,and the TGF-β1/SMAD3 pathway activation.

关键词： Particulate matter TGF-β1 Oxidative stress Epithelial-mesenchymal transition Pulmonary fibrosis Cells

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Modeling functional brain connections in methamphetamine and opioid abusers

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Medicine in Novel Technology and Devices 2024年第1期21卷 88-96页

作者： Nasimeh Marvi javad Haddadnia mohammad Reza Fayyazi Bordbar Hakim Sabzevari University SabzevarIran Psychiatry and Behavioral Sciences Research Center Mashhad University of Medical SciencesMashhadIran

Substance abuse has become a significant problem *** primary purpose of this study was to model the functional brain connectivity in methamphetamines(Meth)and opioids(Op)groups in comparison with the healthy control(HC)*** data were recorded in Meth(n=8),Op(n=12),and HC groups(n=12)in a closed-eye resting *** NeuCube model based on a spiking neural network was used for EEG data's functional brain connectivity *** NeuCube model was evaluated quantitatively and qualitatively with model descriptive *** results showed the average value of the neuron's activation level,spikes emitted from neurons,and clustering coefficient as a communication parameter in the HC group decreased from 1154,1103,0.026 to 1036,981,0.020 in the Op group and to 511,468,0.009 in the Meth group,*** changes in indices were significant according to the ANOVA test with p〈*** decrease in indices was more significant in the Meth group than in the Op *** research findings showed that the abuse of Meth and Op causes damage to the brain's functional *** damage included shortening and limiting communication routes and decreased neurons'ability to generate membrane potential and emit inhibitory and excitatory *** were reported to be more severe in the Meth group than in the Op group.

关键词： Electroencephalogram Methamphetamines NeuCube model Opioids Spiking neural networks

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Interplay between temperature-dependent strengthening mechanisms and mechanical stability in high-performance austenitic stainless steels

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International Journal of Minerals,Metallurgy and Materials 2024年第10期31卷 2182-2188页

作者： mohammad javad Sohrabi Hamed Mirzadeh Saeed Sadeghpour Milad Zolfipour Aghdam Abdol Reza Geranmayeh and Reza Mahmudi School of Metallurgy and Materials Engineering College of EngineeringUniversity of Tehran14395-515 TehranIran Centre for Advanced Steels Research Materials and Mechanical EngineeringUniversity of Oulu90014 OuluFinland Department of Mechanical Engineering College of EngineeringUniversity of Tehran14395-515 TehranIran

The effects of deformation temperature on the transformation-induced plasticity(TRIP)-aided 304L,twinning-induced plasti-city(TWIP)-assisted 316L,and highly alloyed stable 904L austenitic stainless steels were compared for the first time to tune the mechan-ical properties,strengthening mechanisms,and strength-ductility *** this purpose,the scanning electron microscopy(SEM),electron backscattered diffraction(EBSD),X-ray diffraction(XRD),tensile testing,work-hardening analysis,and thermodynamics calcu-lations were *** induced plasticity effects led to a high temperature-dependency of work-hardening behavior in the 304L and 316L stainless *** the deformation temperature increased,the metastable 304L stainless steel showed the sequence of TRIP,TWIP,and weakening of the induced plasticity mechanism;while the disappearance of the TWIP effect in the 316L stainless steel was also ***,the solid-solution strengthening in the 904L superaustenitic stainless steel maintained the tensile properties over a wide temper-ature range,surpassing the performance of 304L and 316L stainless *** this regard,the dependency of the total elongation on the de-formation temperature was less pronounced for the 904L alloy due to the absence of additional plasticity *** results re-vealed the importance of solid-solution strengthening and the associated high friction stress for superior mechanical behavior over a wide temperature range.

关键词： austenitic stainless steels mechanical behavior stacking fault energy metastability mechanical twinning

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未热解厚热障涂层的隔热能力和黏接强度

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Transactions of Nonferrous Metals Society of China 2024年第4期34卷 1226-1236页

作者： mohammad IZADINIA Reza SOLTANI Mahmoud HEYDARZADEH SOHI javad MOSTAGHIMI School of Metallurgy and Materials Engineering College of EngineeringUniversity of TehranTehranIran Centre for Advanced Coating Technologies Department of Mechanical and Industrial EngineeringUniversity of TorontoTorontoOntarioCanada

对比研究使用未热解粉末制备的厚热障涂层(UPTTBC)和传统TBC、厚TBC(TTBC)及密集垂直裂纹(DVC)TTBC 4种涂层的隔热能力和黏接强度。采用降温法测试涂层的隔热能力;根据ASTM C633标准,采用拉拔试验检测涂层的黏接强度。结果显示,UPTTBC和... 详细信息

对比研究使用未热解粉末制备的厚热障涂层(UPTTBC)和传统TBC、厚TBC(TTBC)及密集垂直裂纹(DVC)TTBC 4种涂层的隔热能力和黏接强度。采用降温法测试涂层的隔热能力;根据ASTM C633标准,采用拉拔试验检测涂层的黏接强度。结果显示,UPTTBC和DVC TTBC的黏接强度分别比TTBC高35%和25%。这可能是由于UPTTBC结构中存在亚微米尺度的未熔化区域,起到了阻止裂纹扩展的作用。此外,隔热测试的结果表明,DVCTTBC涂层的隔热能力最差,为0.28℃/μm,而UPTTBC涂层的隔热能力最强,为0.40℃/μm。由于UPTTBCs显微组织中存在亚微米区域,使涂层展现出优越的隔热能力。相反,DVCTTBC因其致密的结构,具有最低的隔热能力。

关键词：厚热障涂层密集垂直裂纹热障涂层未热解粉末黏接强度隔热能力

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Temperature-jump tensile tests to induce optimized TRIP/TWIP effect in a metastable austenitic stainless steel

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International Journal of Minerals,Metallurgy and Materials 2024年第9期31卷 2025-2036页

作者： mohammad javad Sohrabi Hamed Mirzadeh Saeed Sadeghpour Abdol Reza Geranmayeh Reza Mahmudi School of Metallurgy and Materials Engineering College of EngineeringUniversity of Tehran14395-515TehranIran Centre for Advanced Steels Research Materials and Mechanical EngineeringUniversity of Oulu90014 OuluFinland

In the present work,plastic deformation mechanisms were initially tailored by adjusting the deformation temperature in the range of 0 to 200℃ in AISI 304L austenitic stainless steel,aiming to optimize the strength-ductility *** was shown that the combined twinning-induced plasticity(TWIP)/transformation-induced plasticity(TRIP)effects and a wider strain range for the TRIP effect up to higher strains by adjusting the deformation temperature are good strategies to improve the strength-ductility synergy of this metastable stainless *** this regard,by consideration of the observed temperature-dependency of plastic deformation,the controlled sequence of TWIP and TRIP effects for archiving superior strength-ductility trade-off was intended by the pre-designed temperature jump tensile ***,the optimum tensile toughness of 846 MJ/m^(3) and total elongation to 133% were obtained by this strategy via exploiting the advantages of the TWIP effect at 100℃ and the TRIP effect at 25℃ at the later stages of the ***,a deformation-temperature-transformation(DTT)diagram was developed for this metastable ***,based on work-hardening analysis,it was found that the main phenomenon constraining further improvement in the ductility and strengthening was the yielding of the deformation-induced α′-martensite.

关键词： metastable stainless steels transformation-induced plasticity twinning-induced plasticity stacking fault energy mechanical properties

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Period–Luminosity Relationship forδScuti Stars Revisited

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Research in Astronomy and Astrophysics 2024年第2期24卷 138-143页

作者： Atila Poro S.javad Jafarzadeh Roghaye Harzandjadidi mohammad Madani Elnaz Bozorgzadeh Esfandiar Jahangiri Ahmad Sarostad Ailar Alizadehsabegh Maryam Hadizadeh mohammad EsmaeiliVakilabadi The Raderon AI Laboratory Astronomy DepartmentBurnabyBCCanada Department of Physics University of Texas at Dallas800 W.Campbell Rd.RichardsonTX 75080USA Department of Theoretical Physics and Astrophysics University of ZanjanZanjanIran Independent researcher TehranIran Department of Electronics and Telecommunications Politecnico Di TorinoTurinItaly Independent researcher IsfahanIran Yazd Desert Night Sky Astronomy Institute YazdIran Department of Photonics Tabriz UniversityTabrizIran Khayyam Astronomy Association FarsFasaIran

The Gaia DR3 parallax approach was used to estimate the absolute parameters of 2375δScuti stars from the ASAS *** selected stars have a variety of observational characteristics,with a higher than 80%probability of beingδScuti *** have displayed all the stars in the Hertzsprung-Russell diagram along with theδScuti instability strip,the Zero Age Main Sequence and the Terminal Age Main ***,we determined which fundamental and overtone modes each star belongs to using pulsation constant(Q)*** addition,we evaluated the parameters in the Q calculation equation using three machine learning methods,which showed that surface gravity and temperature have the greatest effect on its *** Period-Luminosity(P-L)relationship of theδScuti stars was also ***,using least squares linear regression,we made four linear fits for fundamental and overtone modes and updated their relationships.

关键词： stars variables delta Scuti--stars fundamental parameters-methods data analysis

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Neuroprotective potential of traditional Ayurvedic Kadha:age-related neurological disorders:a comprehensive literature review

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Traditional Medicine Research 2024年第9期9卷 51-77页

作者： Sarvin Sadreddini mohammad javad Emami Kazemabad Sogand Sheikholeslami Kosar Chitzan-Zadeh mohammad Taha Kouchaki Midia Rashidi Amir Abbas Ghayerin Shahin Sabaghi Ghazal Tavakoli Sepehr Nanbakhsh Tina Mansourian Arefeh Tabashiri Fariba Arbab Mojeni Mohammed Namiq Amin Zahra Taheri Seyed Esmaeil Sedighi Taraneh Tarkashvand Parham Amirazodi Mobina Fathi Shirin Yaghoobpoor Niloofar Deravi School of Medicine Tabriz University of Medical SciencesTabriz ***Iran School of Medicine Qom University of Medical SciencesQom ***Iran School of Medicine Hamadan University of Medical SciencesHamadan ***Iran School of Medicine Ahvaz Jundishapur University of Medical SciencesAhvaz ***Iran Faculty of Medicine Tabriz University of Medical SciencesTabriz ***Iran School of Medicine Iran University of Medical SciencesTehran ***Iran School of Medicine Shahid Beheshti University of Medical SciencesTehran ***Iran School of Medicine Mazandaran University of Medical SciencesSari ***Iran School of Medicine Kermanshah University of Medical SciencesKermanshah ***Iran Faculty of Pharmacy Pharmaceutical Sciences BranchIslamic Azad UniversityTehran ***Iran Department of Biology Faculty of SciencePayamNoor UniversityTehran ***Iran Faculty of Medicine Islamic Azad University of Medical ScienceTehran 193951495Iran International Campus Shahid Sadoughi University of Medical SciencesYazd ***Iran

Despite modern medicine’s advancements,age-related neurological diseases like Alzheimer’s disease and Parkinson’s disease remain challenging due to high costs,side effects,and limited ***,a traditional Indian medicine system,offers Kadha tea as a potential herbal *** review explores Kadha’s components(basil(Ocimum basilicum L.),black pepper(Piper nigrum L.),Cinnamon(Cinnamomum verum ***),ginger(Zingiber officinale Roscoe),and raisin(Vitis vinifera L.))and their interaction with various neurological *** suggest Kadha exhibits anti-inflammatory,antioxidant,and antiviral properties,potentially impacting Alzheimer’s disease,Parkinson’s disease,neurotoxicity,neuroinflammation,and brain *** focusing on specific disease mechanisms and Kadha’s intergrade effects,this review aims to elucidate its potential role in managing age-related neurological disorders.

关键词： Ayurveda Kadha neuroprotective neurological disorders traditional medicine

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Strengthening of reinforced concrete beams using fiberreinforced cementitious matrix systems fabricated with custom-designed mortar and fabrics

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Frontiers of Structural and Civil Engineering 2023年第7期17卷 1100-1116页

作者： Ahmadreza RAMEZANI mohammad Reza ESFAHANI javad SABZI Faculty of Engineering Ferdowsi University of MashhadMashhadIran

The performance of a new fiber-reinforced cementitious matrix(FRCM)system developed using custom-designed mortar and fabrics is investigated in this *** behavior of this system is evaluated in terms of both the flexural and shear strengthening of reinforced concrete *** beams are designed to assess the effectiveness of the FRCM system in terms of flexural strengthening,and four specimens are designed to investigate their shear *** parameters investigated for flexural strengthening are the number of layers,span/depth ratio,and the strengthening *** previous studies,custom fabrics with similar axial stiffness are used in all strengthening methods in this *** the shear-strengthened specimens,the effects of the span/depth ratio and strengthening system type(fiberreinforced polymer(FRP)or FRCM)are *** proposed FRCM system exhibits desirable flexural and shear strengthening for enhancing the load capacity,provides sufficient bonding with the substrate,and prevents premature failure *** the similar axial stiffness of fabrics used in both FRCM and FRP systems and the higher load capacity of specimens strengthened by the former,cement-based mortar performs better than epoxy.

关键词： fiber-reinforced cementitious matrix flexural strengthening shear strengthening carbon fiber-reinforced polymer shear span

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Application of Statistical Methods to Biomarkers for Geochemical Evaluation and Genetic Type Determination of Gas Condensates in the Persian Gulf and Coastal Fars,Southern Iran

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Acta Geologica Sinica(English Edition) 2022年第4期96卷 1246-1256页

作者： mohammad javad SEIDY mohammad Hossein SABERI Petroleum Engineering Department Semnan UniversitySemnanIran The New Technology Campus Petroleum Engineering DepartmentSemnan UniversitySemnanIran

In a comprehensive geochemical study,the genetic relationships among 14 samples of gas condensates from the Persian Gulf were investigated for the purpose of evaluating the respective source rocks in terms of both age and sedimentary *** analysis was used for categorization and determination of a certitude range to determine the genetic type of the condensate families in the studied *** samples were collected from Late Permian-Triassic reservoirs(Dalan and Kangan formations)located in 6 gasfields(gas condensate)hosting some of Iran’s most important gas/gas condensate *** by gas chromatography-mass spectrometry(GC-MS),a total of 16 biomarker parameters(10 maturity-related parameters and 6 sedimentary environment-related parameters)were used to evaluate the samples in terms of thermal maturity(and hence their positions in the maturity chart),the sedimentary environment of the source rock and the *** of Hierarchical Clustering Analysis(HCA)and Principal Component Analysis(PCA)to the collected data led to the categorization of the samples into three main genetic groups,Ⅰ-Ⅲ.GroupsⅠandⅢwere found to be located in the east and the west of the Persian Gulf,respectively,while GroupⅡwas developed between the two other groups.

关键词： gas condensate satistical methods genetic linkage thermal maturation Persian Gulf Coastal Fars

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