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In vitro assessment of antioxidant,neuroprotective,anti-urease and anti-tyrosinase capacities of Tamarix africana leaves extracts

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Journal of Traditional Chinese Medicine 2023年第2期43卷 252-264页

作者： Esma Anissa Trad Khodja abd El Hamid Khabtane Rabah Arhab Djamila Benouchenne mohamed Sabri Bensaad Chawki Bensouici Ramazan Erenler Biotechnology WaterEnvironment and Health LaboratoryFaculty of Natural and Life SciencesUniversity Abbes LaghrourKhenchela 40000Algeria Laboratory of Natural Substances Biomolecules and Biotechnological ApplicationsFaculty of Natural and Life SciencesUniversity Larbi Ben M HidiOum El-Bouaghi 04000Algeria Genetics Biochemistry and Plant Biotechnology LaboratoryFaculty of Natural and Life SciencesUniversity Constantine 1Constantine 25000Algeria Pharmaceutical Sciences Research Center Constantine 25000Algeria Laboratory of Cellular and Molecular Physio-Toxicology-Pathology and Biomolecules(LPTPCMB) Faculty of Natural and Life SciencesUniversity Batna 2Batna 05000Algeria Laboratory of Biotechnology of Bioactive Molecules and Cellular Physiopathology(LBMBPC) Faculty of Natural and Life Sciences University Batna 2Batna 05000Algeria Biotechnology Research Center Ali Mendjli UV 03 Constantine 25000Algeria Department of Chemistry Faculty of Science and LiteratureUniversity TokatGaziosmanpasaTokat 60250Turkey

OBJECTIVE:To characterize the chemical profile of methanolic crude extract and its fractions(Ethyl acetate,n-butanol and aqueous)using liquid chromatographymass spectrometry(LC-MS)analysis,to evaluate their biological and pharmacological properties:antioxidant(1,1-diphenyl-2-pycrylhydrazyl(DPPH),2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic)(ABTS·+),galvinoxyle free radical scavenging,reducing power,phenanthroline andβcarotene-linoleic acid bleaching assays),enzymes inhibitory ability against several enzymes[acetylcholinesterase(AChE),buthyrylcholinesterase(BChE),urease and tyrosinase].METHODS:Secondary metabolites were extracted from Tamarix africana air-dried powdered leaves by maceration,the crude extract was fractionated using different solvents with different polarities(Ethyl acetate,n-butanol and aqueous).The amount of polyphenols,flavonoids and tannins(hydrolysable and condensed)were determined using colorimetric assays.A variety of in vitro biochemical tests were carried out to assess antioxidant and oxygen radical scavenging properties using DPPH,ABTS,galvinoxyle free radical scavenging,reducing power,phenanthroline andβcarotene-linoleic acid bleaching *** effect was examined against acetylcholinesterase and buthyrylcholinesterase *** anti-urease and antityrosinase activities were performed against urease and tyrosinase enzymes *** extract’s components were identified using LC-MS and compared to reference ***:The results indicated that Tamarix africana extracts presented a powerful antioxidant activity in all assays and exhibited a potent inhibitory effect against AChE and BChE as well as urease and tyrosinase ***-MS analysis identified amount of eight phenolic compounds were revealed in this analysis;Apigenin,Diosmin,Quercetin,Quercetine-3-glycoside,Apigenin 7-O glycoside,Rutin,Neohesperidin and Wogonin in methanolic extract and its different fractions of Tamarix africana from ***

关键词： antioxidants anti-tyrosinase anti-urease liquid chromatography-mass spectrometry neuroprotection phenolic content Tamarix africana

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Cost of external fixation vs external fixation then nailing in bone infection

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World Journal of Orthopedics 2015年第1期6卷 145-149页

作者： Khaled mohamed Emara Ramy Ahmed Diab Khaled abd EL Ghafar Orthopaedic Surgery Ain Shams University

AIM: To study the cost benefit of external fixation vs external fixation then nailing in treatment of bone infection by segment ***: Out of 71 patients with infected nonunion tibia treated between 2003 and 2006, 50 patients fitted the inclusion criteria(26 patients were treated by external fixation only, and 24 patients were treated by external fixation early removal after segment transfer and replacement by internal fixation). Cost of inpatient treatment, total cost of inpatient and outpatient treatment till full healing, and the weeks of absence fromschool or work were calculated and compared between both ***: The cost of hospital stay and surgery in the group of external fixation only was 22.6 ± 3.3 while the cost of hospital stay and surgery in the group of early external fixation removal and replacement by intramedullary nail was 26.0 ± 3.2. The difference was statistically significant regarding the cost of hospital stay and surgery in favor of the group of external fixation only. The total cost of medical care(surgery, hospital stay, treatment outside the hospital including medications, dressing, physical therapy, outpatient laboratory work, etc.) in group of external fixation only was 63.3 ± 15.1, and total absence from work was 38.6 ± 6.6 wk. While the group of early removal of external fixation and replacement by IM nail, total cost of medical care was 38.3 ± 6.4 and total absence from work or school was 22.7 ± 4.1. The difference was statistically significant regarding the total cost and absence from work in favor of the group of early removal and replacement by IM ***: Early removal of external fixation and replacement by intramedullary nail in treatment of infected nonunion showed more cost effectiveness. Orthopaedic society needs to show the cost effectiveness of different procedures to the community, insurance, and health authorities.

关键词： Cost Fixator Nailing Infection

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以脉冲萃取柱利用三异辛胺从高浓度铀溶液中回收铀（英文）

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无机化学学报 2016年第8期32卷 1427-1433页

作者： mohamed Fathi El-Shahat Hisham mohamed Kamal Reda abd El-Gawad Ghazalla Walid mohamed Morsy Faculty of Science Inorganic Chemistry Department Ain Shams University Cairo Egypt Nuclear Materials A uthority Cairo Egypt

利用三异辛胺(TOA)纯化Gattar小型试验工厂的高浓度铀溶液(洗脱液的铀浓度7 g·L-1),研究了脉冲萃取柱的性能。利用实验室级脉冲萃取柱进行了实验室规模的溶剂萃取实验和后续实验。结果表明,在室温、p H=1和有机相与水相的比例(VO/VA)约... 详细信息

利用三异辛胺(TOA)纯化Gattar小型试验工厂的高浓度铀溶液(洗脱液的铀浓度7 g·L-1),研究了脉冲萃取柱的性能。利用实验室级脉冲萃取柱进行了实验室规模的溶剂萃取实验和后续实验。结果表明,在室温、p H=1和有机相与水相的比例(VO/VA)约为1.8∶1时,加入二(2-乙基己基)磷酸(D2EHPA)使其与TOA的比例(VD2EHPA/VTOA)为2∶3,可使萃取克服Cl-的抑制效应,提高效率。将结论用于考察试验工厂级萃取柱的流体力学和传质性能,结果表明用脉冲萃取柱萃取铀可以达到97%的萃取效率,具有可行性。

关键词：洗脱液氯溶剂萃取法脉冲萃取柱

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A Quantum Algorithm for Evaluating the Hamming Distance

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Computers, Materials & Continua 2022年第4期71卷 1065-1078页

作者： Mohammed Zidan Manal G.Eldin Mahmoud Y.Shams mohamed Tolan Ayman abd-Elhamed Mahmoud abdel-Aty Department of Artificial Intelligence Hurghada Faculty of Computers and Artificial IntelligenceSouth Valley UniversityEgypt Faculty of Engineering King Salman International UniversitySouth SinaiEgypt Department of Mathematics and Computer Science Faculty of ScienceBeni-Suef UniversityBeni-SuefEgypt Department of Machine Learning and Information Retrieval Faculty of Artificial IntelligenceKafrelsheikh UniversityEgypt Mechanical Department Faculty of Technology and EducationSuez UniversitySuezEgypt Faculty of Technological Industries King Salman International UniversitySouth SinaiEgypt Faculty of Engineering at Mataria Helwan UniversityCairoEgypt Department of Mathematics Faculty of SciencesSohag University82524 SohagEgypt

We present a novel quantum algorithm to evaluate the hamming distance between two unknown oracles via measuring the degree of entanglement between two ancillary *** particular,we use the power of the entanglement degree based quantum computing model that preserves at most the locality of interactions within the quantum model *** model uses one of two techniques to retrieve the solution of a quantum computing problem at *** the first technique,the solution of the problem is obtained based on whether there is an entanglement between the two ancillary qubits or *** the second,the solution of the quantum computing problem is obtained as a function in the concurrence value,and the number of states that can be generated from the Boolean *** proposed algorithm receives two oracles,each oracle represents an unknown Boolean function,then it measures the hamming distance between these two *** hamming distance is evaluated based on the second *** is shown that the proposed algorithm provides exponential speedup compared with the classical counterpart for Boolean functions that have large numbers of Boolean *** proposed algorithm is explained via a case ***,employing recently developed experimental techniques,the proposed algorithm has been verified using IBM’s quantum computer simulator.

关键词： Quantum computing quantum algorithm quantum circuit

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Methods to shorten the duration of an external fixator in the management of tibial infections

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World Journal of Orthopedics 2011年第9期2卷 85-92页

作者： Khaled M Emara Khaled abd Al Ghafar mohamed Ahmed Al Kersh Orthopaedic Surgery Ain Shams University HospitalsCairo 0020Egypt Lecturer in Orthopaedic Surgery Ain Shams UniversityCairo 0020Egypt Assistant Lecturer of Orthopaedic Surgery Ain Shams UniversityCairo 0020Egypt

Massive segmental bone loss due to chronic osteomyelitis represents a considerable challenge to orthopedic surgeons and is a limb threatening *** only option available in such a clinical situation is segment transport using the Ilizarov technique of distraction osteogenesis;yet the most common problem in cases of bone transport with the Ilizarov technique in massive bone loss,is the long duration of the *** addition to autologous bone grafting,several mechanical,biologic,and external physical treatment modalities may be employed to promote bone formation and maturation during segment transport in osteomyelitis *** approaches include compressive loading of the distraction regenerate,increased frequency of small increments of distraction,and *** nailing and hemicorticotomy can reduce the time in external fixation;however,these techniques are associated with technical difficulties and *** application of low-intensity pulsed ultrasound or pulsed electromagnetic fields may shorten the duration of external *** promising modalities include diphosphonates,physician-directed use(off-label use)of bone morphogenetic proteins,and local injection of bone marrow aspirate and platelet gel at the osteotomy ***-designed clinical studies are needed to establish safe and effective guidelines for various modalities to enhance new bone formation during distraction osteogenesis after segment transfer.

关键词： Ilizarov Bone infection Intramedullary nail Hemicorticotomy Tibiofibular synostosis Fibular transport

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Enhancing Parkinson’s Disease Diagnosis Accuracy Through Speech Signal Algorithm Modeling

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Computers, Materials & Continua 2022年第2期70卷 2953-2969页

作者： Omar M.El-Habbak abdelrahman M.abdelalim Nour H.mohamed Habiba M.abd-Elaty Mostafa A.Hammouda Yasmeen Y.mohamed Mohanad A.Taifor Ali W.mohamed School of Information Technology and Computer Science Nile UniversityGiza12677Egypt Operations Research Department Faculty of Graduate Studies for Statistical ResearchCairo UniversityGiza12613Egypt Wireless Intelligent Networks Center(WINC) School of Engineering and Applied SciencesNile UniversityGiza12677Egypt

Parkinson’s disease(PD),one of whose symptoms is dysphonia,is a prevalent neurodegenerative *** use of outdated diagnosis techniques,which yield inaccurate and unreliable results,continues to represent an obstacle in early-stage detection and diagnosis for clinical professionals in the medical *** solve this issue,the study proposes using machine learning and deep learning models to analyze processed speech signals of patients’voice *** of these processed speech signals were obtained and experimented on by random forest and logistic regression *** were highly successful,with 90%accuracy produced by the random forest classifier and 81.5%by the logistic regression ***,a deep neural network was implemented to investigate if such variation in method could add to the *** proved to be effective,as the neural network yielded an accuracy of nearly 92%.Such results suggest that it is possible to accurately diagnose early-stage PD through merely testing patients’*** research calls for a revolutionary diagnostic approach in decision support systems,and is the first step in a market-wide implementation of healthcare software dedicated to the aid of clinicians in early diagnosis of PD.

关键词： Early diagnosis logistic regression neural network Parkinson’s disease random forest speech signal processing algorithms

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Influence of ECAP as grain refinement technique on microstructure evolution, mechanical properties and corrosion behavior of pure aluminum

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Transactions of Nonferrous Metals Society of China 2015年第12期25卷 3865-3876页

作者： mohamed Ibrahim abd EL AAL M.M.SADAWY Mechanical Design and Production Department Faculty of Engineering Zagazig University Mining and Petroleum Engineering Department Al-Azhar University

Pure aluminum samples were processed by equal channel angular pressing（ECAP） up to 10 passes at room temperature. The effects of the ECAP number of passes on the microstructure evolution, the mechanical properties, deformation homogeneity and corrosion behavior of the processed samples were fully investigated. The imposed strain resulted in an obvious reduction in the grain size from 390 μm before ECAP down to 1.8, 0.4, and 0.3 μm after ECAP up to 2, 4 and 10 passes, respectively. The microhardness, deformation homogeneity and tensile strength were increased while the elongation decreased with the increase of ECAP number of passes. Immersion tests, open circuit potential, Tafel polarization, cyclic polarization and potentiostatic measurements in 3.5% Na Cl solution revealed an obvious improvement in the corrosion resistance of ECAP processed samples compared with the as-cast sample. The increase of the number of passes can be used successfully in producing ultra-fine grained（UFG） bulk pure aluminum sample with a high misorientation angle, reasonably high mechanical properties and corrosion resistance.

关键词： equal channel angular pressing(ECAP) microstructure mechanical properties corrosion resistance passive film pitting

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Micropunch grafting for healing of refractory chronic venous leg ulcers

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Chinese Journal of Plastic and Reconstructive Surgery 2022年第4期4卷 166-170页

作者： Aya mohamed Samy Mostafa abd El-Halim Ahmed Hassan El-Sabbagh Department of Plastic and Reconstructive Surgery Mansoura University HospitalMansoura 35516Egypt Plastic Surgery Center Faculty of MedicineMansoura UniversityMansoura 35516Egypt

Background: Chronic venous ulcers are a serious problem for both patients and physicians. The CEAP classification(clinical manifestations(C), etiologic factors(E), anatomic distribution of disease(A), and underlying pathophysiologic findings(P)) for chronic venous disorders(CVD) was developed in 1994. Published papers on CVD use all or part of the CEAP. Micropunch grafts, which are a variation of skin grafts, have been used with great success in plastic surgery for both esthetic and reconstructive purposes. This study aimed to assess the outcomes of micropunch grafting in the treatment of chronic refractory venous ***: Patients with chronic venous ulcers who did not respond to conservative treatment for more than 6months were included in the study. All patients underwent ulcer coverage by micropunch skin grafts using a micrometer. The patients were discharged on the same day as the surgery. Micropunch skin grafts were manually counted per square centimeter intraoperatively and during follow-up using Dermlite DermatoschopeTM II Pro *** satisfaction was assessed by using a ***: Twenty patients underwent the surgery. Most of the patients were middle-aged males. The ulcers were predominantly small-and medium-sized. The mean operation time was 167.00 ± 86.01 min. After 6 months, the survival rate of the planted micrografts was 84%. Three ulcers had graft loss and two patients had an infection at the ulcer site, which was managed conservatively. The patients were followed-up for 14 ***: Micropunch grafting is a useful and convenient method for the treatment of difficult venous ulcers and can be performed on an outpatient basis.

关键词： Venous ulcer Micropunch grafting

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Influence of Recycling Waste Glass as Fine Aggregate on the Concrete Properties

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Journal of Renewable Materials 2023年第6期11卷 2925-2940页

作者： Rafal A.Hadi Suhad M.abd Hadee Mohammed Najm Shaker Qaidi Moutaz Mustafa A.Eldirderi Khaled mohamed Khedher Department of Civil Engineering Bilad Alrafidain University CollegeDiyala32001Iraq Department of Civil Engineering College of EngineeringUniversity of DiyalaDiyala32001Iraq Department of Civil Engineering Zakir Husain Engineering CollegeAligarh Muslim UniversityAligarh202002India Department of Civil Engineering College of EngineeringUniversity of DuhokDuhok42001Iraq Department of Civil Engineering College of EngineeringNawroz UniversityDuhok42001Iraq Department of Chemical Engineering College of EngineeringKing Khalid UniversityAbha61421Saudi Arabia Department of Civil Engineering College of EngineeringKing Khalid UniversityAbha61421Saudi Arabia Department of Civil Engineering High Institute of Technological StudiesMrezgua University CampusNabeul8000Tunisia

Recent years have witnessed an increase in the quantity of waste glass(WG)across the *** the fine aggregate with WG is one of the steps toward preserving the natural resources of the environment and creating low-cost *** present study is concerned with replacing fine aggregates with glass powder(GP)at(0%,15%,30%,and 50%).It has studied the fresh and hardened properties(compressive strength,tensile strength,hardened density,and slump)for all the mentioned percent *** findings have shown that all mixtures containing GP gave acceptable slump results within the design limits(2–5 cm)according to ACI standard *** has been observed that increasing the proportion of GP led to a decrease in the weight of ***,replacing GP with sand by 30%has led to an increase in the compressive strength by about 2.4%and 12.45%,and the tensile strength by about 2.5%and 26.54%at 7-and 28-d,respectively in comparison to normal concrete.

关键词： Sustainable concrete glass powder fine aggregate partial replacement

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Robust Machine Learning Technique to Classify COVID-19 Using Fusion of Texture and Vesselness of X-Ray Images

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Computer Modeling in Engineering & Sciences 2024年第2期138卷 1981-2004页

作者： Shaik Mahaboob Basha Victor Hugo Cde Albuquerque Samia Allaoua Chelloug mohamed abd Elaziz Shaik Hashmitha Mohisin Suhail Parvaze Pathan Department of Electronics and Communication Engineering N.B.K.R.Institute of Science&TechnologyVidyanagarAndhra Pradesh524413India Department of Teleinformatics Engineering Federal University of CearáFortaleza60455-970Brazil Information Technology Department College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityRiyadh84428Saudi Arabia Department of Mathematics Faculty of ScienceZagazig UniversityZagazig44519Egypt Faculty of Computer Science and Engineering Galala UniversitySuez435611Egypt Artificial Intelligence Research Center(AIRC) College of Engineering and Information TechnologyAjman UniversityAjmanUnited Arab Emirates Department of Electrical and Computer Engineering Lebanese American UniversityByblos13-5053Lebanon Department of Avionics Indian Institute of Space Science and TechnologyThiruvananthapuramKerala695547India Department of Veterinary Clinical Sciences University of MinnesotaSt.PaulMinnesota55108USA

Manual investigation of chest radiography(CXR)images by physicians is crucial for effective decision-making in COVID-19 ***,the high demand during the pandemic necessitates auxiliary help through image analysis and machine learning *** study presents a multi-threshold-based segmentation technique to probe high pixel intensity regions in CXR images of various pathologies,including normal *** information is extracted using gray co-occurrence matrix(GLCM)-based features,while vessel-like features are obtained using Frangi,Sato,and Meijering *** learning models employing Decision Tree(DT)and RandomForest(RF)approaches are designed to categorize CXR images into common lung infections,lung opacity(LO),COVID-19,and viral pneumonia(VP).The results demonstrate that the fusion of texture and vesselbased features provides an effective ML model for aiding *** ML model validation using performance measures,including an accuracy of approximately 91.8%with an RF-based classifier,supports the usefulness of the feature set and classifier model in categorizing the four different ***,the study investigates the importance of the devised features in identifying the underlying pathology and incorporates histogrambased *** analysis reveals varying natural pixel distributions in CXR images belonging to the normal,COVID-19,LO,and VP groups,motivating the incorporation of additional features such as mean,standard deviation,skewness,and percentile based on the filtered ***,the study achieves a considerable improvement in categorizing COVID-19 from LO,with a true positive rate of 97%,further substantiating the effectiveness of the methodology implemented.

关键词： Chest radiography(CXR)image COVID-19 classifier machine learning random forest texture analysis

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