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Computer Technology and Application 2011年第4期2卷 319-323页

作者： Sharfi Mustafa Abass mohamed sayed farag Othman Bin Ibrahim Computer Science Dept. Computer Science and Information Technology Universiti Teknologi Malaysia＆ Majmaah University Johor ＆ Magmmah Malaysia＆ KSA Computer Science Dept. Faculty of Science Al-Azhar University Cairo Egypt Computer Science Dept. Computer Science and Information Technology Universiti Teknologi Malaysia University Johor Malaysia

In this paper, the authors proposed a model, to build trust in the infrastructure between the Consumer-to-Consumer （C2C） and some proposals, to increase the trust in building the infrastructure for electronic commerce between consumers C2C through a comparison of previous studies, which have been applied in many countries like America, China, France, Korea, and Philippines. In their work the authors focused on the relation between consumers C2C which is more successful than the Business-to-Consumer （B2C）, Business-to-Business （B2B）, and is more systems suitable for developing countries and have been applied in China.

关键词： Consumer-to-consumer (C2C) e-commerce building trust infrastructure.

Wood By-Products as UV Protection:A Consequence Review

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Journal of Renewable Materials 2024年第4期12卷 699-720页

作者： Naglaa Salem El‑sayed mohamed Hasanin Samir Kamel Cellulose and Paper Department National Research CentreCairo12622Egypt

In recent decades,the ozone layer has suffered considerable damage,increasing the entry of ultraviolet(UV)light into the atmosphere and reaching the earth’s surface,negatively affecting ***,researchers aimed to solve this problem by synthesizing advanced UV-shielding *** the other hand,developing an easy and green strategy to prepare functional materials with outstanding properties based on naturally abundant and environmentally friendly raw materials is highly desirable for sustainable *** biomass-derived materials are sustainable and biodegradable,they present a promising substitute for petroleum-based *** three main structural constituents of the plant biomass-based materials that are naturally available are cellulose,hemicellulose,and *** review details current developments using wood-based products such as cellulose,hemicellulose,and lignin in UV-shielding *** will start with assembling the structure and chemistry of cellulose,hemicellulose,and lignin,followed by their contributions to preparing UV-shielding ***,it will briefly discuss the different processing methods for the design of UV-shielding *** wood by-products offer additional opportunities to use the whole tree harvest.

关键词： UV-shielding wood cellulose lignin hemicellulose sunlight protection

Pyronaridine combined with diminazene aceturate inhibits Babesia in vitro and in vivo

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Asian Pacific Journal of Tropical Biomedicine 2024年第3期14卷 93-99页

作者： Shimaa Abd El-Salam El-sayed mohamed Z.sayed-Ahmed Shaimaa Ahmed Awad Ali Nourah Alsadaan Nawazish Alam Mahmoud S.Alkhoudary Ikuo Igarashi mohamed Abdo Rizk National Research Center for Protozoan Diseases Obihiro University of Agriculture and Veterinary MedicineInada-ChoObihiroHokkaido 080-8555Japan Department of Biochemistry and Chemistry of Nutrition Faculty of Veterinary MedicineMansoura UniversityMansoura 35516Egypt Department of Clinical Pharmacy College of PharmacyJazan UniversityJazan 45142Saudi Arabia Medical-Surgical Department College of NursingJouf UniversitySakaka 72388Saudi Arabia Critical Care and Emergency Nursing Faculty of NursingMansoura UniversityEgypt College of Nursing Jouf UniversitySakaka 72388Saudi Arabia Faculty of Pharmacy Mansoura UniversityMansoura 35516DakahliaEgypt Department of Internal Medicine and Infectious Diseases Faculty of Veterinary MedicineMansoura UniversityMansoura 35516Egypt

Objective:To evaluate the combination therapy of pyronaridine tetraphosphate and diminazene aceturate against Babesia in vitro and in ***:Bioinformatic analysis was performed using atom pair *** in vitro combination test was performed against Babesia bovis and Theileria ***,the in vivo chemotherapeutic efficacy of pyronaridine tetraphosphate in combination with diminazene aceturate was investigated against the growth of Babesia microti in mice using a fluorescence inhibitory ***:Pyronaridine tetraphosphate and diminazene aceturate exhibited nearly similar molecular *** in vitro combination of pyronaridine tetraphosphate and diminazene aceturate was synergistic on Babesia bovis and additive on Theileria *** addition,5 mg/kg pyronaridine tetraphosphate combined with 10 mg/kg diminazene aceturate inhibited Babesia microti growth significantly compared with those observed after treatment with 25 mg/kg diminazene aceturate alone from day 6 post treatment to day 12 post *** combination therapy also normalized the hematological parameters of infected ***:An oral dose of pyronaridine tetraphosphate combined with a subcutaneous dose of diminazene aceturate inhibits Babesia in vitro and in mice,suggesting it might be a new paradigm for the treatment of babesiosis.

关键词： Babesia Pyronaridine tetraphosphate Diminazene aceturate Babesiosis Theileria

Ultralong hydroxyapatite-based forward osmosis membrane for freshwater generation

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Frontiers of Chemical Science and Engineering 2024年第9期18卷 37-49页

作者： mohamed Gamal Gomaa Hamdy Maamoun Abdel-Ghafar Francesco Galiano Francesca Russo Alberto Figoli El-sayed Ali Abdel-Aal Abdel-Hakim Taha Kandil Bahaa Ahmed Salah Central Metallurgical Research and Development Institute(CMRDI) 11421 CairoEgypt Chemistry Department Faculty of ScienceHelwan University11795 CairoEgypt Institute on Membrane Technology(CNR-ITM) 87036 RendeItaly

Increasing global water shortages are accelerating the pace of membrane manufacturing,which generates many environmentally harmful *** challenges need a radical rethink of developing innovative membranes that can address freshwater production without generating environmentally harmful *** work utilized the synthesized ultra-long hydroxyapatite(UHA)by the solvothermal method using the green solvent oleic acid in preparing UHA-based forward osmosis *** membranes were developed using different loading ratios of graphene oxide(GO)by vacuum-assisted filtration *** prepared GO/UHA membranes were identified using X-ray diffraction,scanning electron microscope,Fourier-transform infrared spectroscopy,and X-ray photoelectron *** contact angle and pore size distribution were determined for the obtained GO/UHA *** obtained hierarchical porous structure in the prepared membranes with interconnected channels results in a stable water flux with reverse salt *** best water flux rate of 42±2 L·m^(–2)·h^(–1)was achieved using the 50 mg GO/UHA membrane,which is 3.3 times higher than the pristine membrane,and a reverse salt flux of 67 g·m^(-2)·h^(–1).The obtained results showed a promising capability of a new generation of sustainable inorganic-based membranes that can be utilized in freshwater generation by energy-efficient techniques such as forward osmosis.

关键词： forward osmosis ultra-long hydroxyapatite graphene oxide inorganic-based membrane

Volatile organic compounds for the detection of hepatocellular carcinoma—A scoping review

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iLIVER 2024年第1期3卷 45-51页

作者： sayed Metwaly Alicja Psica Opeyemi Sogaolu Irfan Ahmed Ashis Mukhopadhya Mirela Delibegovic mohamed Bekheit Division of Internal Medicine Aberdeen Royal InfirmaryNHS GrampianScotlandAberdeenAB252ZDUnited Kingdom Aberdeen Cardiovascular and Diabetes Centre School of MedicineMedical Sciences and NutritionUniversity of AberdeenForesterhill Health CampusAberdeenAB252ZDUnited Kingdom Department of Critical Care Medicine University of CalgaryAlberta T2N 2T9Canada Department of General Surgery Aberdeen Royal InfirmaryNHS GrampianScotlandAberdeen AB252ZDUnited Kingdom Pakistan Kidney and Liver Institute and Research Centre Lahore 54000Pakistan Hépatica Centre of Integrated HPB CareElite HospitalAlexandria 21325Egypt

Hepatocellular carcinoma(HCC)is an increasingly common and the second leading cause of cancer mortality worldwide with a 5-year survival rate about 12%.Less than 20%of HCC patients are eligible to curative treatment owing to the late ***,there is a need for a readily accessible,early screening *** scoping review critically appraises and synthesizes the current published knowledge about the use of exhaled volatile organic compounds(VOCs)as a potential noninvasive means for HCC detection aiming to advance this nascent field.A systematic electronic search was *** search strategy included all studies published until the 24th of March 2023 using a combination of relevant *** search yielded 9 publications using the Preferred Reporting Items for Systematic Reviews and Meta-analyses *** of the studies described in vitro experiments,and seven clinical studies were conducted on small groups of ***,42 headspace gases were analyzed in the in vitro ***,the clinical studies included 420 HCC patients and 630 *** studies reported potential role for a combination of VOCs in the diagnosis of ***,there is lack of *** there appears to be promise in VOCs research associated with HCC,there is no single volatile biomarker in exhaled breath attributed to HCC and data from extracted studies indicates a lack of *** multicentre population studies are required to verify the existence of VOCs linked to HCC.

关键词： Hepatocellular carcinoma Volatile organic compounds Metabolomics

Insights into the anorexic mechanism of Khat:an integrated in vivo,ex vivo,and in silico investigations

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Traditional Medicine Research 2024年第10期9卷 36-51页

作者： Ahmed Ali Jerah Manal mohamed Elhassan Taha Abdullah Farasani Sivakumar Sivagurunathan Moni Emad sayed Shaheen Andleeb Khan Ibrahim Abdo Khardali Magbool Oraiby Heyam mohamed Ali Sidahmed Siddig Ibrahim Abdelwahab Department of Medical Laboratory Technology College of Applied Medical SciencesJazan UniversityJazan 45142Saudi Arabia Health Research Centre Jazan UniversityJazan 45142Saudi Arabia Department of Pharmaceutics College of PharmacyJazan UniversityJazan 45142Saudi Arabia Department of Biosciences Faculty of ScienceIntegral UniversityLucknow 226026India Poison Control and Medical Forensic Chemistry Center General Directorate of Health AffairsJazan 45142Saudi Arabia Department of Pharmaceutical Chemistry Faculty of PharmacyAl-Neelain UniversityKhartoum 16458Sudan

Background:Chewing Khat(Catha edulis)releases cathine and cathinone,which may reduce appetite via an unknown *** study investigated the peripheral and central effects of fresh leaves and buds of Catha edulis water extract(CEWE)on appetite biomarkers,gene expression,and body weight,using in vivo,ex vivo,and in silico ***:Rats of both sexes were orally administered CEWE at different doses and durations in three different *** chromatography-mass spectroscopy(LC-MS)-MS was used to detect cathinone and cathine in the murine *** effect of Khat on serotonin receptors was studied in isolated rat fundus *** of the two Khat ligands was performed on G(The 5-hydroxytryptamine-type 2C receptor(5-HT2C)in an agonist-bound active conformation)and H(5-HT2C in an antagonist-bound inactive conformation)proteins to determine which ligands are most likely to act as agonists or ***:Significant differences(P0.05).The expression of the ghrelin and leptin genes was also unaffected,but the expression of the 5-hydroxytryptamine(5-HT)gene decreased(P<0.05)with CEWE *** antagonizes 5-HT receptors in isolated rat fundus *** findings indicated that the khat ligands bound to 5-HT2C *** and cathinone levels in rat plasma were ***:Khat extract may suppress appetite by antagonizing the 5-HT *** research is required to understand its mechanism and potential applications.

关键词： Catha edulis appetite leptin ghrelin 5-hydroxytryptamine molecular docking

FlowBreakdown of Hybrid Nanofluid on a Rigid Surface with Power Law Fluid as Lubricated Layers

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Computer Modeling in Engineering & Sciences 2024年第2期138卷 1485-1499页

作者： Mirza Naveed Jahangeer Baig NadeemSalamat Sohail Nadeem NaeemUllah mohamed Bechir Ben Hamida Hassan Ali Ghazwani sayed M.Eldin A.S.Al-Shafay Instituite of Mathematics Khwaja Fareed University of Engineering and Information TechnologyRahim yar Khan64200Pakistan Department of Mathematics Quaid-I-Azam UniversityIslamabad44000Pakistan Department of Mathematics Wenzhou UniversityWenzhou325035China College of Engineering Department of Mechanical EngineeringImam Mohammad Ibn Saud Islamic University(IMSIU)Riyadh11564Saudi Arabia Research Laboratory of Ionized Backgrounds and Reagents Studies(EMIR) Preparatory Institute for Engineering Studies of Monastir(IPEIM)University of MonastirMonastir5060Tunisia Higher School of Sciences and Technology of Hammam Sousse Department of PhysicsJazan82511Kingdom of Saudia Arabia Department of Mechanical Engineering Faculty of engineeringJazan UniversityP.O.Box 45124JazanKingdom of Saudia Arabia Center of Research Faculty of EngineeringFuture University in EgyptNew Cairo11835Egypt Department of Mechanical Engineering College of EngineeringPrince Sattam bin Abdulaziz UniversityAlkharj16436Saudi Arabia

Thiswork investigates an oblique stagnation point flowof hybrid nanofluid over a rigid surface with power lawfluidas lubricated layers. Copper (Cu) and Silver (Ag) solid particles are used as hybrid particles acting in water H2O asa base fluid. The mathematical formulation of flow configuration is presented in terms of differential systemthat isnonlinear in nature. The thermal aspects of the flow field are also investigated by assuming the surface is a heatedsurface with a constant temperature T. Numerical solutions to the governing mathematical model are calculatedby the RK45 algorithm. The results based on the numerical solution against various flow and thermal controllingparameters are presented in terms of line graphs. The specific results depict that the heat flux increases over thelubricated-indexed parameter.

关键词： Oblique stagnation point flow hybrid nanofluid lubricated layer magnetohydrodynamics

Gastrointestinal and hepatic diseases during the COVID-19 pandemic:Manifestations,mechanism and management

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World Journal of Gastroenterology 2021年第28期27卷 4504-4535页

作者： Dina Zakaria mohamed Mai El-sayed Ghoneim Sally El-sayed Abu-Risha Ramy Ahmed Abdelsalam mohamed Abdelhalem farag Department of Pharmacology and Toxicology Faculty of PharmacyTanta UniversityTanta 31511Egypt Department of Pharmacology and Toxicology Faculty of PharmacyUniversity of Sadat CityMenoufia 32632Egypt Department of Pathology Faculty of MedicineMansoura UniversityMansoura 35511Egypt Department of Pediatrics Nebru General HospitalNebru 35511Egypt

Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is considered the causative pathogen of coronavirus disease 2019(COVID-19)and has become an international danger to human *** respiratory transmission and symptoms are still the essential manifestations of COVID-19,the digestive system could be an unconventional or supplementary route for COVID-19 to be transmitted and manifested,most likely due to the presence of angiotensin-converting enzyme 2(ACE2)in the gastrointestinal *** addition,SARS-CoV-2 can trigger hepatic injury via direct binding to the ACE2 receptor in cholangiocytes,antibodydependent enhancement of infection,systemic inflammatory response syndrome,inflammatory cytokine storms,ischemia/reperfusion injury,and adverse events of treatment *** symptoms,including anorexia,nausea,vomiting,and diarrhea,which are unusual in patients with COVID-19,and some digestive signs may occur without other respiratory ***,SARS-CoV-2 can be found in infected patients’stool,demonstrating the likelihood of transmission through the fecal-oral *** addition,liver function should be monitored during COVID-19,particularly in more severe *** review summarizes the evidence for extra-pulmonary manifestations,mechanisms,and management of COVID-19,particularly those related to the gastrointestinal tract and liver.

关键词： COVID-19 Angiotensin-converting enzyme 2 Gastrointestinal Inflammatory bowel disease Liver Management

Experimental and parametrical investigation of pre-stressed ultrahigh-performance fiberreinforced concrete railway sleepers

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Frontiers of Structural and Civil Engineering 2023年第3期17卷 411-428页

作者： sayed AHMED Hossam ATEF mohamed HUSAIN Department of Structural Engineering Faculty of EngineeringZagazig UniversityZagazig 44519Egypt Track Work Department National Authority for TunnelsCairo 11522Egypt

In this study,ultrahigh-performance fiber-reinforced concrete(UHPFRC)used in a type B70 concrete sleeper is investigated experimentally and *** main parameters investigated are the steel fiber volume fractions(0%,0.5%,1%,and 1.5%).Under European standards,35 UHPFRC sleepers are subjected to static bending tests at the center and rail seat sections,and the screw on the fastening system is pulled *** first cracking load,failure load,failure mode,crack propagation,load–deflection curve,load–crack width,and failure load from these tests are measured and compared with those of a control sleeper manufactured using normal concrete *** accuracy of the parametric study is verified ***,the results of the study are applied to UHPFRC sleepers with different concrete volumes to investigate the effects of the properties of UHPFRC on their *** and parametric study results show that the behavior of UHPFRC sleepers improves significantly when the amount of steel fiber in the mix is *** manufactured using UHPFRC with a steel fiber volume fraction of 1%and a concrete volume less than 25%that of standard sleeper B70 can be used under the same loads and requirements,which contributes positively to the cost and surrounding environment.

关键词： pre-stressed concrete sleeper ultrahigh performance fiber-reinforced concrete pull-out test static bending test steel fiber aspect ratio volume fraction

Seismic performance of high-rise buildings in selected regions in Saudi Arabia according to different seismic codes

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Earthquake Engineering and Engineering Vibration 2021年第1期20卷 179-191页

作者： sayed Mahmoud mohamed Alsearheed Waleed Abdallah Department of Civil and Construction Engineering College of EngineeringImam Abdulrahman Bin Faisal UniversitySaudi Arabia Department of Building Engineering College of ArchitectureImam Abdulrahman Bin Faisal UniversitySaudi Arabia Department of Civil Engineering College of Engineering at MatariaHelwan UniversityCairoEgypt

The design code for each country is revised and updated based on an expected zone’s seismic intensities,geotechnical site classifications,structural systems,construction materials and methods of construction in order to provide more realistic considerations of seismic demand,seismic response,and seismic *** on the aforementioned provisions,structures designed according to different seismic codes may yield different performances for the same level of *** study aims to investigate and compare the induced responses related to the earthquake-resistant design of reinforced concrete(RC)buildings according to the Saudi building code(SBC-301),American code(ASCE-7),uniform building code(UBC-97),and European code(EC-8).In order to account for the provision regarding the hazard specification and its effect on the induced seismic responses,four regions in the Kingdom of Saudi Arabia with different seismic levels are *** code provisions related to the specification of site classification and its effect on the induced design base shear are investigated as *** differences are observed in the induced responses with the variation in seismic design codes for the considered seismic hazards and site classifications.

关键词： high-rise building SBC-301 international seismic codes seismic zones site classifications