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Open Journal of Radiology 2024年第2期14卷 74-82页

作者： Mousa Bakkari Khaled Soliman Abdullah Alrushoud Marwan fahad Alosaimi Hanaa Alsheikh Abdelwahed Alhejaili Medical Physics Department Prince Sultan Military Medical City Riyadh Saudi Arabia Radiogiadnostic and Medical Imaging Department Prince Sultan Military Medical City Riyadh Saudi Arabia

This study aims to estimate the lifetime attributable cancer risk (LAR) for pediatric chest computed tomography (CT) examinations in five age groups using recently published age and region-specific conversion coefficients multiplying the widely available scanner registered dose length products (DLP) displayed on the CT console and hence calculating the Effective Dose (ed). The ed is then multiplied by the International Commission on Radiological Protection (ICRP) published risk factor for LAR. The obtained LAR values are compared with the international literature. Factors that may affect the LAR value are reported and discussed. The study included one hundred twenty five chest CT examinations for both males and females aged from less than one year to fifteen years. The patients reported data are from one single medical institution and using two CT scanners from June 2022 to December 2023. The results of this study may serve as benchmark for institutional radiation dose reference levels and risk estimation.

关键词： Cancer Risk LAR Chest CT Pediatric Radiology Radiation Dose DLP

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电化学传感器在食品添加剂检测中的应用

食品安全导刊 2024年第21期 148-150页

作者：米雪甘肃畜牧工程职业技术学院甘肃武威733006

食品添加剂在改善食品品质方面发挥着重要作用,但非法添加或超量使用会危害消费者健康。电化学传感器凭借灵敏度高、选择性好、快速、成本低等优点,在食品添加剂检测中展现出广阔的应用前景。本文分析了电化学传感器在抗氧化剂、甜味剂... 详细信息

食品添加剂在改善食品品质方面发挥着重要作用,但非法添加或超量使用会危害消费者健康。电化学传感器凭借灵敏度高、选择性好、快速、成本低等优点,在食品添加剂检测中展现出广阔的应用前景。本文分析了电化学传感器在抗氧化剂、甜味剂、色素等食品添加剂检测方面的应用,提出采用纳米材料修饰电极、分子印迹技术构建传感器是其主要发展方向。新型电化学传感器的研制有望进一步提高食品添加剂检测的灵敏度和选择性,为保障食品安全提供重要的技术支撑。

关键词：电化学传感器食品添加剂纳米材料分子印迹食品安全

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Assessment of knowledge, attitude and practice regarding oxygen therapy at emergency departments in Riyadh in 2017: A cross-sectional study

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World Journal of Emergency Medicine 2019年第2期10卷 88-93页

作者： Amairah fahad Aloushan Faisal Abdullah Almoaiqel Raid Naysh Alghamdi Fatmah Ismail Alnahari Abdulaziz fahad Aldosari Nazish Masud Nawfal Abdullah Aljerian College of Medicine King Saud Bin Abdulaziz University for Health Sciences Department of Medical education College of Medicine King Saud bin Abdulaziz University for Health Sciences Riyadh Department of Emergency Medicine King Abdulaziz Medical City

BACKGROUND: Administering oxygen therapy(OT) has an essential role in preventing/managing hypoxemia in both acute and chronic conditions. It should be adjusted to achieve the normal oxygen saturation of 94%–98% in most cases. This study aims to evaluate knowledge, attitude and practice(KAP) of nurses, paramedics, emergency medical technicians(EMTs) and Emergency Medical Services(EMS) physicians working at emergency departments(ed) in Riyadh, Saudi Arabia. METHODS: In this cross-sectional study, a structured questionnaire was used to assess KAP related to OT of nurses, paramedics, EMTs and EMS physicians currently working at an ed of a tertiary care hospital. Knowledge and attitude were assessed using a Likert scale from 1–5, whereas practice was assessed as a yes/no categorical ***: A total of 444 emergency health-care workers(EHCWs) participated, of which 225(50.7%) were male, with the majority(77%) in the age group of 20–35 years. Over half of the sample were nurses(266; 59.9%). The mean score for knowledge about OT was 5.51±1.45, attitude was 26.31±3.17 and for practices 4.55±1.76. The main factors which were associated with poor KAP were workload and lack of local guidelines. The distribution of overall practice score was signifi cantly better among paramedics – nurses group and EMT – nurses ***: This study demonstrates that there is a gap in EHCWs' KAP, particularly regarding when to provide OT to a patient. This gap can affect patients' safety. Extensive educational and training programs about OT are needed to raise awareness among health-care providers.

关键词： Emergency medicine Oxygen therapy Knowledge Attitude Practice

血小板参数联合骨髓涂片在血液疾病患者诊断中的应用分析

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实用医技杂志 2024年第4期31卷 275-278页

作者：谭咪杨旭文南阳市第一人民医院西区医院检验科南阳473000

目的分析血液疾病诊断过程中,血小板参数联合骨髓涂片的应用价值。方法选取我院63例血液疾病患者作为观察组[其中急性白血病(AL)、特发性血小板减少性紫癜(ITP)组21例和再生障碍性贫血(AA)各21例],对照组选择同期来院的健康体检者63名,... 详细信息

目的分析血液疾病诊断过程中,血小板参数联合骨髓涂片的应用价值。方法选取我院63例血液疾病患者作为观察组[其中急性白血病(AL)、特发性血小板减少性紫癜(ITP)组21例和再生障碍性贫血(AA)各21例],对照组选择同期来院的健康体检者63名,所有受检者接受骨髓涂片、血小板参数检测,比较不同检验方式的灵敏度、特异度与准确性。结果与对照组相比,AL组、AA组与ITP组的血小板压积(PCT)、血小板计数(PLT)水平较低(P<0.05),血小板体积分布宽度(PDW)水平较高(P<0.05);ITP组的血小板平均体积MPV水平高于对照组(P<0.05),AL组、AA组的MPV水平低于对照组(P<0.05)。骨髓涂片联合血小板参数的阳性检出率、灵敏度、特异度、准确率85.7%(54/63)、98.0%(49/50)、61.5%(8/13)、90.5%(57/63)高于骨髓涂片82.0%(41/50)、23.1%(3/13)、69.8%(44/63)(χ^(2)=7.111,3.939,8.433,P=0.008,0.047,0.004),差异有统计学意义。结论血液疾病诊断中使用血小板参与联合骨髓涂片诊断,能有效区分健康人与血液疾病患者,还能有效区分AL、ITP与AA几种疾病类型,且联合诊断的灵敏度、特异度与准确率高于单独的骨髓涂片诊断。

关键词：血液病骨髓涂片血小板诊断

HCloud:A Trusted JointCloud Serverless Platform for IoT Systems with Blockchain

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China Communications 2020年第9期17卷 1-10页

作者： Zheng Huang Zeyu mi Zhichao Hua Institute of Parallel and Distributed Systems Shanghai Jiao Tong UniversityShanghai 200240China

Cloud computing has been exploited in managing large-scale IoT *** cloud servers usually handle a large number of requests from various IoT *** to the fluctuant and heavy workload,the servers require the cloud to provide high scalability,stable performance,low price and necessary ***,traditional clouds usually offer computing service with the abstraction of virtual machine(VM),which can hardly meet these ***,different cloud vendors provide different performance stabilities and price models,which fluctuate according to the dynamic workload.A single cloud cannot satisfy all the requirements of the IoT scenario *** JointCloud computing model empowers the cooperation among multiple public ***,it is still difficult to dynamically schedule the workload on different clouds based on the VM *** paper introduces HCloud,a trusted JointCloud platform for IoT systems using serverless computing *** allows an IoT server to be implemented with multiple serverless functions and schedules these functions on different clouds based on a schedule *** policy is specified by the client and includes the required functionalities,execution resources,latency,price and so *** collects the status of each cloud and dispatches serverless functions to the most suitable cloud based on the schedule *** leveraging the blockchain technology,we further enforce that our system can neither fake the cloud status nor wrongly dispatch the target *** have implemented a prototype of HCloud and evaluated it by simulating multiple cloud *** evaluation results show that HCloud can greatly improve the performance of serverless workloads with negligible costs.

关键词： IoT blockchain serverless jointcloud

Hybrid Smart Contracts for Securing IoMT Data

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Computer Systems Science & Engineering 2023年第1期44卷 457-469页

作者： D.Palanikkumar Adel fahad Alrasheedi P.Parthasarathi S.S.Askar moha.ed Abouhawwash Department of Computer Science and Engineering Dr NGP Institute of TechnologyCoimbatore641048India Department of Statistics and Operations Research College of ScienceKing Saud UniversityRiyadh11451Saudi Arabia Department of Computer Science and Engineering Bannari Amman Institute of TechnologySathy638401India Department of Mathematics Faculty of ScienceMansoura UniversityMansoura35516Egypt Department of Computational Mathematics Scienceand Engineering(CMSE)Michigan State UniversityEast LansingMI48824USA

Data management becomes essential component of patient *** of Medical Things(IoMT)performs a wireless communication between E-medical applications and human *** of consulting a doctor in the hospital,patients get health related information remotely from the *** main issues in the E-Medical application are lack of safety,security and priv-acy preservation of patient’s health care *** overcome these issues,this work proposes block chain based IoMT Processed with Hybrid consensus protocol for secured *** health data is collected from physician,smart devices *** main goal is to store this highly valuable health related data in a secure,safety,easy access and less cost-effective *** this research we combine two smart contracts such as Practical Byzantine Fault Tolerance with proof of work(PBFT-PoW).The implementation is done using cloud technology setup with smart contracts(PBFT-PoW).The accuracy rate of PBFT is 90.15%,for PoW is 92.75%and our proposed work PBFT-PoW is 99.88%.

关键词： PoW byzantine fault tolerance IoMT cloud computing health care data

Hybrid Convolutional Neural Network for Plant Diseases Prediction

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Intelligent Automation & Soft Computing 2023年第5期36卷 2393-2409页

作者： S.Poornima N.Sripriya Adel fahad Alrasheedi S.S.Askar moha.ed Abouhawwash Department of Information Technology Sri Sivasubramaniya Nadar College of EngineeringChennai603110India Department of Statistics and Operations Research College of ScienceKing Saud UniversityRiyadh11451Saudi Arabia Department of Mathematics Faculty of ScienceMansoura UniversityMansoura35516Egypt Department of Computational Mathematics Scienceand Engineering(CMSE)Michigan State UniversityEast LansingMI48824USA

Plant diseases prediction is the essential technique to prevent the yield loss and gain high production of agricultural *** monitoring of plant health continuously and detecting the diseases is a signiﬁcant for sustainable *** system to monitor the diseases in plant is time consuming and report a lot of *** is high demand for technology to detect the plant dis-eases *** image processing approach and deep learning approach are highly invited in detection of plant *** diseases like late blight,bacterial spots,spots on Septoria leaf and yellow leaf curved are widely found in *** are the main reasons to affects the plants life and *** identify the diseases earliest,our research presents the hybrid method by com-bining the region based convolutional neural network(RCNN)and region based fully convolutional networks(RFCN)for classifying the *** the leaf images of plants are collected and preprocessed to remove noisy data in *** data normalization,augmentation and removal of background noises are *** images are divided as testing and training,training images are fed as input to deep learning ***,we identify the region of interest(RoI)by using selective *** every region,feature of convolutional neural network(CNN)is extracted independently for further classiﬁ*** plants such as tomato,potato and bell pepper are taken for this *** plant input image is analyzed and classify as healthy plant or unhealthy *** the image is detected as unhealthy,then type of diseases the plant is affected will be *** proposed technique achieves 98.5%of accuracy in predicting the plant diseases.

关键词： Disease detection people detection image classiﬁcation deep learning region based convolutional neural network

Effect of expanding nanocellulose sponge on nasal mucosal defects in an animal model

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Regenerative Biomaterials 2020年第1期7卷 47-52页

作者： JiWon Kim Kyungbae Woo Jeong mi Kim mi Eun Choi Young-Mo Kim Su-Geun Yang Bong Sup Shim Jeong-Seok Choi Department of Otorhinolaryngology Inha UniversityCollege of Medicine27 Inhang-roJung-guIncheon 22332Republic of Korea Department of Chemical Engineering Inha University100 InharoMichuholguIncheon 22212Republic of Korea Department of New Drug Development Inha UniversityCollege of MedicineB-308Chungsuk Bldg.366Seohae-DaeroJung-GuIncheon 22332Republic of Korea

Nanocellulose has emerged for a wide range of applications in biomedical engineering because of its water absorption capacity,appropriate *** investigated the hemostatic and regenerative abilities of an expanding polyvinyl alcohol(PVA)-nanocellulose sponge on nasal mucosal defects.A 3 mm-diameter nasal defect was made in experimental *** were divided into four groups with control,vaseline,PVA and PVA-nanocellulose packing *** the defect was created,bleeding times and amounts were *** materials were removed on experimental day(ed)*** ed 3,7 and 14,histological analysis and immunohistochemical study for neutrophils were *** cells were counted and epithelial thicknesses were *** amounts and times in the vaseline packing group were smaller than in the PVA ***-nanocellulose group showed less neutrophils than in the other groups on ed *** epithelium thickness in the PVA-nanocellulose group was significantly smaller than in the control group at ed 7,but at ed 14,there was no significant intergroup *** group had a significant lower inflammatory cell count than the control group on ed ***-nanocellulose sponge applied to nasal mucosal defects can significantly enhance mucosal regeneration during early wound healing.

关键词： polyvinyl alcohol nasal mucosa nanocellulose

Sliding Mode Control-Based Autonomous Control of a Tri-rotor Unmanned Aerial Vehicle

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Guidance, Navigation and Control 2021年第3期1卷 52-75页

作者： Abid Raza fahad Mumtaz Malik Rameez Khan Naveed Mazhar Hameed Ullah Nigar Ahmed Department of Electrical Engineering College of Electrical and Mechanical EngineeringNational University of Sciences and Technology46000IslamabadPakistan College of Automation Engineering Nanjing University of Aeronautics and AstronauticsNanjingJiangsu 210016P.R.China

A nonlinear control technique for autonomous control of a tri-rotor unmanned aerial vehicle is presented in this ***,a comprehensive mathematical model is developed using the Newton–Euler approach for a tri-rotor,which is found to be highly nonlinear and ***,the equivalent input a±ne model is extracted by applying a suitable ***,the sliding mode control for trajectory tracking is chosen which is immune to matched external disturbances,parametric uncertainties,and modeling *** proposed controller performance has been veri¯ed for appropriate inputs under wind disturbances using MATLAB,and the simulation results are presented.

关键词： Autonomous control nonlinear control sliding mode control unmanned aerial vehicle tri-rotor

Hyperoside protects the blood-brain barrier from neurotoxicity of amyloid beta 1–42

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Neural Regeneration Research 2018年第11期13卷 1974-1980页

作者： Chen-Yang Liu Kuan Bai Xiao-Hui Liu Li-mi Zhang Gu-Ran Yu Department of Neurology Jiangsu Traditional Chinese Medicine Hospital the Affiliated Hospital of Nanjing University of Traditional Chinese Medicine Nanjing Jiangsu Province China Graduate School of Nanjing University of Traditional Chinese Medicine Nanjing Jiangsu Province China

Mounting evidence indicates that amyloid β protein（Aβ） exerts neurotoxicity by disrupting the blood-brain barrier（BBB） in Alzheimer＇s disease. Hyperoside has neuroprotective effects both in vitro and in vivo against Aβ. Our previous study found that hyperoside suppressed Aβ1-42-induced leakage of the BBB, however, the mechanism remains unclear. In this study, bEnd.3 cells were pretreated with 50, 200, or 500 μM hyperoside for 2 hours, and then exposed to Aβ1-42 for 24 hours. Cell viability was determined using 3-（4,5-dimethyl-2-thiazolyl）-2,5-diphenyl-2-H-tetrazolium bromide assay. Flow cytometry and terminal deoxynucleotidyl transferase-mediated d UTP nick-end labeling assay were used to analyze cell apoptosis. Western blot assay was carried out to analyze expression levels of Bax, Bcl-2, cytochrome c, caspase-3, caspse-8, caspase-9, caspase-12, occludin, claudin-5, zonula occludens-1, matrix metalloproteinase-2（MMP-2）, and MMP-9. Exposure to Aβ1-42 alone remarkably induced bEnd.3 cell apoptosis; increased ratios of cleaved caspase-9/caspase-9, Bax/Bcl-2, cleav ed caspase-8/caspase-8, and cleaved caspase-12/caspase-12; increased expression of cytochrome c and activity of caspase-3; diminished levels of zonula occludens-1, claudin-5, and occludin; and increased levels of MMP-2 and MMP-9. However, hyperoside pretreatment reversed these changes in a dose-dependent manner. Our findings confirm that hyperoside alleviates fibrillar Aβ1-42-induced BBB disruption, thus offering a feasible therapeutic application in Alzheimer＇s disease.

关键词： nerve regeneration Alzheimer's disease amyloid beta 1-42 blood-brain barrier bEnd.3 cells tight junction proteins hyperoside anti-apoptosis neural regeneration