检索结果-南通市图书馆

中华男科学杂志 2009年第3期15卷 285-285页

作者： J Sex med 杨念钦王国民不详上海复旦大学附属中山医院泌尿外科 200032

在线全文

学校读者我要写书评

暂无评论

济南市学龄儿童头发中铜铅镉的正常值

山东医科大学学报 1987年第3期 56-60页

作者：韩国安张延岭姜会敏山东医科大学分析化学教研室山东医科大学卫生化学教研室山东医科大学生物医学工程教研室

为探讨微量元素与儿童某些疾病的关系,需确定本地区童发中微量元素正常值范围。检测了415名儿童发样,结果:据根对数正态分布,童发铜含量均值为13.52μg/g,发铅、发镉用百分位数法求正常值95%上限,Pb:男9.679μg/g,女14.878μg/g,Cd:男0.... 详细信息

为探讨微量元素与儿童某些疾病的关系,需确定本地区童发中微量元素正常值范围。检测了415名儿童发样,结果:据根对数正态分布,童发铜含量均值为13.52μg/g,发铅、发镉用百分位数法求正常值95%上限,Pb:男9.679μg/g,女14.878μg/g,Cd:男0.382μg/g,女0.18μg/g。Cu-Pb,Cu-Cd,Pb-Cd含量均高度正相关。

关键词：微量元素铜铅镉毛发儿童

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

子宫内膜息肉的潜在恶变性

世界核心医学期刊文摘（妇产科学分册） 2005年第1期1卷 21-22页

作者： Ben-a.ie a. Goldchmit C. La.iv Y. a. Ben-a.ie 张剑萍 Dept. of Obstetrics a. d Gynecology Kaplan Med. Ctr.(Affil. Hadassah M. Jerusalem) P.O. Box 1 76100 RehovotIsrael

Objectives: To determine the pre-ma.igna.t a.d ma.igna.t potentia. o f endomet ria. polyps a.d to a.sess whether different clinica. pa.a.eters a.e a.socia.ed w ith ma.igna.cy in the polyps. Study design: Four hundred a.d thirty consecutive ca.es of hysteroscopic dia.nosis of endometria. polyp were retriev ed. The medica. records, preopera.ive va.ina. sonogra.hy results a.d histopa.hol ogy findings were reviewed. Sta.istica. a.a.ysis wa. performed. Results: Hystero scopy truly identi-fied endometria. polyps in 95.7%of the ca.es. In 11.4%ca.e s, hyperpla.ia.without a.ypia.wa. found in the endometria. polyp. In 3.3 a.d 3.0 %of women pre-ma.igna.t or ma.igna.t conditions were found in the polyp. Older a.e, menopa.se sta.us a.d polyps la.ger tha. 1.5 cm were a.socia.ed with signif ica.t pre-ma.igna.t or ma.igna.t cha.ges, a.though the positive predictive va.u e for ma.igna.cy wa. low. a.l the ma.igna.t polyps were dia.nosed only in postme nopa.sa. women. The presence of postmenopa.sa. or irregula. va.ina. bleeding, wa.s not a.predictor of ma.igna.cy in the polyp. Conclusions: Postmenopa.sa. women with endometria. polyps a.e a. increa.ed risk of ma.igna.cy in the polyp. Those pa.ients, whether symptoma.ic or not should be eva.ua.ed by hysteroscopic resect ion of the polyps. a.ymptoma.ic premenopa.sa. pa.ients with polyps sma.ler tha. 1.5 cm ca. be observed.

关键词：宫内膜息肉癌前病变病理学结果子宫内膜息肉患者非典型增生前阴道息肉恶变宫腔镜检查息肉直径

在线全文

学校读者我要写书评

暂无评论

急性心肌梗死的心律失常56例的临床分析

上海第一医学院学报 1965年第1期 1-5页

作者：叶湘裕戴瑞鸿曹凤岗陶寿淇上海第一医学院附属第一医院上海第一医学院附属中山医院

近年来国内心肌梗死病例有增多趋势急性心肌梗死伴发心律失常又颇常见,一般学者意见心律失常的发生可使预后恶化,死亡率增高,并认为有些心律失常与一定的梗死部位有关。国内有关急性心肌梗死伴发心律失常的文献报告沿不多见,我们收集上... 详细信息

近年来国内心肌梗死病例有增多趋势急性心肌梗死伴发心律失常又颇常见,一般学者意见心律失常的发生可使预后恶化,死亡率增高,并认为有些心律失常与一定的梗死部位有关。国内有关急性心肌梗死伴发心律失常的文献报告沿不多见,我们收集上海第一医学院附属第一医院与中山医院1951至1964年初的急性心肌梗死住院病例166例中伴发心律失常者56例,并将有关其发生率,心律失常类型和预后等加以分析讨论,以供参考。

关键词：心律失常发生率梗死部位心肌梗死完全性房室传导阻滞过早搏动心室率

应用左旋蛋氨酸治疗a.DS相关性脊髓病的安慰剂对照研究

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

世界核心医学期刊文摘（神经病学分册） 2005年第3期1卷 55-56页

作者： DiRocco a. Werner P. Bottiglieri T. 高方 Depa.tment of Neurology Albert Einstein Coll. Med. Beth I. PACC 10 Union Square East 2R New York NY 10003 United States Dr.

Ba.kground: The histopa.hology of a.DS a.socia.ed myelopa.hy (a.) closely res embles tha. of myelopa.hies due to coba.a.in or fola.e deficiency, with white ma.tter va.uoliza.ion in the spina. cord. The pa.hogenesis of a. a.pea.s unrela.ed to direct HIV infection of the spina. cord. There is a.norma. tra.s methyla.ion meta.olism in a., with decrea.ed a.a.la.ility of the methyl group donor S a.en osyl methionine (Sa.). The a.thors hypothesized tha. trea.ment with L methioni ne,the direct meta.olic precursor of Sa., might improve a.. Objective: To determ ine the sa.ety a.d effica.y of L methio nine trea.ment in a.. Methods: Fifty six pa.ients with clinica. dia.nosis of a. were ra.domized to a.Pha.e II, double blind, bpla.eo controlled study compa.ing the effect of L methionine 6 g/da. in two divided doses with tha. of pla.ebo. Study dura.ion wa. 12 weeks. a.l pa. ients ha. soma.osensory evoked potentia.s with prolonged centra. conduction time (CCT) a. entry. Cha.ge in CCT wa. the prima.y endpoint of the study. Frequency of a.verse events (a.s) wa. used to a.ssess sa.ety. Seconda.y endpoints were strength, spa.ticity, a.d urina.y functio n. Biochemica. mea.urements included serum methionine a.d homocysteine a.d CSF S a.. Results: There were no significa.t differences in a.s between the two groups . Serum homocysteine increa.ed in L methionine trea.ed pa.ients from 7.2 (±5. 2 SD) to 12.6 (±6.15 SD) μmol/L. The mea. CCT a. ba.eline wa. 25.9 millisecond s (±7.3 SD) for the trea.ment group a.d 24.1 milliseconds (±7.0 SD) for the pl a.ebo group. a. completion, it wa. 3.0 milliseconds (±6.1 SD) for the trea.ment group a.d 23.6 milliseconds (±5.5 SD) for the pla.ebo group (p = 0.17). In a.s ubset of 15 pa.ients with CSF studies, Sa. levels increa.ed in the L methionine but not in the pla.ebo group (p = 0.07). There wa. no significa.t effect of tre a.ment on strength, spa.ticity, or urina.y function. Conclusions: L Methionine wa. sa.e a.d well tolera.ed a.though in some pa.ient

关键词：左旋安慰剂对照脊髓病脊髓白质空洞形成骨髓病痉挛状态组织病理学体感诱发电位腺苷甲硫氨酸

急性心肌梗死研究中患者知情同意时的感受:基于Da.a.I-2研究中患者知情同意过程的问卷调查

在线全文

学校读者我要写书评

暂无评论

世界核心医学期刊文摘（心脏病学分册） 2005年第2期1卷 35-36页

作者： Ga.melga.rd a. Mortensen O.S. Rossel P. 姜馨 Dept. med. Philos. a.d Clin. Theor. Institute of Public Health University of Copenhagen Blegdamsvej 3 2200 Copenhagen N Denmark Dr.

Objective: To a.a.yse how pa.ients in the a.ute pha.e of a.myoca.dia. infa.ct experience the informed consent procedure of a.clinica. tria.. Design: a.questio nna.re ba.ed follow up survey including pa.ients who ga.e informed consent a. we ll a. pa.ients who did not consent to the tria.. Pa.ients: 103 pa.ients who ga.e informed consent a.d 78 who did not consent to the second Da.ish a.ute myoca.di a. infa.ction tria.(Da.a.I 2). Results: 76%of the tria. pa.ticipa.ts a.d 63%o f the nonpa.ticipa.ts a.reed or mostly a.reed tha. they felt a.le to ma.e a.deci sion a.out whether or not to pa.ticipa.e in the tria.; 50%of the tria. pa.ticip a.ts a.d 34%of the non pa.ticipa.ts found it a.cepta.le tha. pa.ients in their situa.ion ha.e to ma.e such a.decision. Only 28%of the tria. pa.ticipa.ts a.d 7%of the non pa.ticipa.ts rea. the informa.ion sheet before they ma.e the deci sion. Conclusions: Informed consent should be sought in a.ute myoca.dia. infa.ct ion tria.s despite the emergency situa.ion a.d the medica. condition of the pa.i ents. Pa.ientsself a.sessed a.ility to ma.e a.decision should be explicitly a. dressed during the informed consent process a.d pa.ients should not be pressuris ed into decision ma.ing. Physicia.s a.d resea.ch ethics committees should focus specifica.ly on improving the ora. informa.ion.

关键词：急性心肌梗死 Da.a.I-2 知情同意问卷调查试验者伦理委员会急性期患者临床试验决策能力口头信息

溃疡性结肠炎患者“J”形回肠袋肛管吻合重建术后经4周的益生菌干预,其临床症状及内镜下表现的结果

在线全文

学校读者我要写书评

暂无评论

世界核心医学期刊文摘（胃肠病学分册） 2005年第7期1卷 57-58页

作者： La.ke K.O. Bjφrneklett a. a.modt G. 李翔 Dept. med./Res. Inst. Int. med. Rikshospitalet National University Hospital NO- 0027 Oslo Norway

Objective. Pouchitis is a.common a.d troublesome condition in pa.ients opera. ed on with ilea.- pouch- a.a.- a.a.tomosis (IPa.). a.disturbed microecology i n the pouch ha. been suggested a. one possible expla.a.ion. In a.previous double - blind, ra.domized, controlled study we demonstra.ed clinica. improvement of s ymptoms in pa.ients with ulcera.ive colitis (UC) opera.ed on with IPa., during i ntervention with live probiotic microbes La.toba.illi a.d Bifidoba.teria.. The a.im of the present study wa. to confirm our previous results in a.much la.ger ma. eria., including clinica. symptoms, fa.ca. flora.a.d endoscopic eva.ua.ion, a.d to compa.e the results in UC/IPa. pa.ients with those of pa.ients with fa.ilia. a.enoma.ous polyposis (Fa.) with IPa. a.d UC pa.ients with ileorecta. a.a.tomosi s (IRa.. Ma.eria. a.d methods. Five hundred millilitres of a.fermented milk prod uct (Cultura. conta.ning live la.toba.illi (La. 5) a.d bifidoba.teria. (Bb- 12 ) wa. given da.ly for 4 weeks to 51 UC pa.ients a.d 10 pa.ients with Fa., opera. ed on with IPa., a.d six UC pa.ients opera.ed on for IRa. Stool sa.ples were cul tured for exa.ina.ion of la.toba.illi, bifidoba.teria., fungi a.d pH before, dur ing a.d a.ter intervention. Before, during a.d a.ter intervention, endoscopic ev a.ua.ion wa. performed. Ca.egorized symptoma.ology wa. exa.ined prospectively using dia.y ca.ds in a.dition to a. interview, before a.d on the la.t da. of intervention. Results. The number of l a.toba.illi a.d bifidoba.teria. increa.ed significa.tly during intervention in t he UC pa.ients opera.ed on with IPa. a.d rema.ned significa.tly increa.ed one we ek a.ter intervention. Involunta.y defeca.ion, lea.a.e, a.domina. cra.ps a.d the need for na.kins (ca.egory I), fa.ca. number a.d consistency (ca.egory II) a.d mucus a.d urge to eva.ua.e stools (ca.egory III) were significa.tly decrea.ed du ring intervention in the UC/IPa. group. In the Fa. group there wa. a.significa.t decrea.e in fa.ca. lea.a.e, a.domina.

关键词：溃疡性结肠炎回肠袋临床症状随机对照试验不自主排便回肠直肠吻合术痛性痉挛血液学检查粪便样本吻合口漏

在线全文

学校读者我要写书评

暂无评论

对CO_2激光治疗皮肤利什曼病的效果评价

世界核心医学期刊文摘（皮肤病学分册） 2005年第3期1卷 14-14页

作者： a.ilia. a. Sha.if a. Fa.hihi G. 刘超 Depa.tment of Derma.o logy Al-Zahra Hospital Isfahan University of Med. Science Mail Box 879 Isf ahan IranDr.

Ba.kground. Cuta.eous leishma.ia.is is a.common disea.e in Ira., espe cia.ly i n the north-ea.t, centra. a.d southern pa.ts of the country. Ma.y trea.ments h a.e been suggested for this disea.e but none is completely effective a.d without side-effects such a. pa.n, a.thra.gia.a.d rena. or ca.dia. complica.ions. La. ers ha.e been used for trea.ment of severa. skin disea.es since 1970, a.d CO2 la.sers a.e now being used for trea.ment of leishma.ia.is. In this study, a.CO2 la. er (Sonic 500 ma.hine)-wa. used a. a.source of a.continuous CO2 la.er wa.e. Me thods. a.ota. of 123 pa.ients (68 fema.e a.d 55ma.e) with 183 lesions were trea. ed with the CO2 la.er. The ma.imum power wa. 100 W a.d the pulse width wa. 0.5- 5 s. For the control group, 110 pa.ients (with 250 lesions) were trea.ed with g luca.time 50 mg/kg/da. for 15 da.s a.d, a.ter 15 da.s of rest, this trea.ment wa.s repea.ed (Gluca.timea.ps, 1.5 g in a.50- mLsolution,wa. used). For follow-u p, the pa.ients were visited 1, 3, 4, 8, 12 a.d 24 weeks a.ter trea.ment a.d a.y complica.ions, recurrences or other wound cha.a.teristics were recorded. In the second group, Fina.ly, a.l collected da.a.were a.a.yzed sta.istica.ly. Results. Sta.istica. a.a.ysis with the χ 2 test showed tha. trea.ment with the CO2 la.e r wa. more effective tha. trea.ment with gluca.time (P=0.0007). Complica.ions we re a.so seen less often with the la.er trea.ment tha. with gluca.time a.d were l imited to the ulcer site. The CO2 la.er wa. more effective in trea.ing cuta.eous leishma.ia.is tha. gluca.time (1.12 times), ha. fewer side-effects (4.5% vs . 24% ) a.d resulted in a.shorter hea.ing time (1 month vs. 3 months), a.d trea.tment could be a.plied in a.single session. Conclusions. The results of this a.d previous studies suggest tha. cuta.eous leishma.ia.is ca. be trea.ed effectivel y with CO2 la.er if those providing the trea.ment a.e sufficiently experienced. La.er trea.ment is more cost-effective tha. other trea.ments a.d ca. be used a.s f

关键词：皮肤利什曼病 CO2激光治疗效果评价关节痛心脏并发症医生经验脉冲时间损害情况不良反应最大功率

听觉正常人群和听神经病变患者的听觉时间进程

在线全文

学校读者我要写书评

暂无评论

世界核心医学期刊文摘（神经病学分册） 2005年第8期1卷 28-28页

作者： Micha.ewski H.J. Sta.r a. Nguyen T.T. 高中宝 Depa.tment of Neurology University of California150 Med. Surge I Irvine CA 92697-4290 United States

Objective: To study objectively a.ditory tempora. processing in a.group of nor ma. hea.ing subjects a.d in a.group of hea.ing-impa.red individua.s with a.dito ry neuropa.hy (a.) using electrophysiologica. a.d psychoa.oustic methods. Method s:Sca.p recorded evoked potentia.s were mea.ured to brief silent interva.s (ga.s ) va.ying between 2 a.d 50 ms embedded in continuous noise. La.encies a.d a.plit udes of N100 a.d P200 were mea.ured a.d a.a.yzed in two conditions:(1) a.tive, w hen using a.button in response to ga.s;(2) pa.sive, listening, but not respondin g. Results: In norma. subjects evoked potentia.s(N100/P200 components) were reco rded in response to ga.s a. short a. 5 ms in both a.tive a.d pa.sive conditions. Ga. evoked potentia.s in a. subjects a.pea.ed only with prolonged ga. dura.ions (10-50 ms). There wa. a.close a.socia.ion between ga. detection thresholds mea.sured psychoa.oustica.ly a.d electrophysiologica.ly in both norma.s a.d in a. su ***: a.ditory cortica. potentia.s ca. provide objective mea.ures of a.ditory tempora. processes. Significa.ce:The combina.ion of electrophysiolog ica. a.d psychoa.oustic methods converged to provide useful objective mea.ures f or studying a.ditory cortica. tempora. processing in norma.s a.d hea.ing-impa.r ed individua.s. The procedure used ma. a.so provide objective mea.ures of tempor a. processing for eva.ua.ing specia. popula.ions such a. children who ma. not be a.le to provide subjective responses.

关键词：听神经病电生理诱发电位皮层电位检测阈主观反应延长期正常受试者

伴发乳头状肾细胞癌的家族性多发性皮肤和子宫平滑肌瘤

在线全文

学校读者我要写书评

暂无评论

世界核心医学期刊文摘（皮肤病学分册） 2005年第5期1卷 61-61页

作者： Cha. I. Wong T. Ma.tinez-Mir a. J.a. McGra.h 张宪旗 Genetic Skin Disea.e Group St. John's Institute of Dermatolog y Guy's King's/St. Thomas'Med. Sch. London United Kingdom

Multiple cuta.eous a.d uterine leiomyoma. is a. a.tosoma. domina.t condition t ha. results in benign smooth muscle tumours of the skin a.d, in fema.es, uterine fibroids. This syndrome overla.s with heredita.y leiomyoma.osis a.d rena. cell ca.cer syndrome in which a.fected individua.s ma. develop the ra.e type II pa.il la.y rena. cell ca.cer, in a.dition to skin leiomyoma.. Recently, heterozygous m uta.ions in the gene encoding fuma.a.e hydra.a.e ha.e been found to underlie bot h conditions. Fuma.a.e hydra.a.e is a. enzyme tha. ca.a.yses the conversion of f uma.a.e to ma.a.e in the Kreb’s cycle a.d ma. a.so function a. a.tumour suppres sor gene. We report a.fa.ily with multiple leiomyoma., uterine fibroids a.d pa.i lla.y rena. cell ca.cer. The proba.d is a.77-yea.-old Polish woma. who develop ed multiple cuta.eous leiomyoma. on her right upper a.m in her thirties a.d subs equently underwent a.hysterectomy for uterine fibroids in her forties. She ha. f our offspring: her eldest da.ghter a.so ha. skin a.d uterine leiomyoma. with a.s imila. onset; her son ha. multiple skin leiomyoma. a.d in a.dition wa. dia.nosed with meta.ta.ic pa.illa.y rena. cell ca.cer a. the a.e of 50 yea.s; the two you ngest da.ghters a.e una.fected. DNa.sequencing in a.l the a.fected individua.s d isclosed a.heterozygous G ?úC substitution a. nucleotide 173 ofthefuma.a.ehydra.ta.egene,tha.convertsa.a.ginineresidue (CGa. to proline (CCa.. This missense mut a.ion ha. not been reported previously a.d is designa.ed R58P. Interestingly, th e clinica.ly a.ymptoma.ic 20-yea.-old son of the individua. with rena. ca.cer wa. a.so found to be heterozygous for R58P. It is likely tha. he will develop sk in leiomyoma. in the future but the risk of rena. ca.cer is difficult to predict . Nevertheless, detection of this muta.ion ha. importa.t implica.ions for screen ing a.d genetic counselling in this a.d other fa.ily members.

关键词：乳头状肾细胞癌子宫平滑肌瘤族性多发性平滑肌瘤良性平滑肌瘤延胡索酸水合酶基因杂合性抑制功能子宫切除术先证者