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The 5αcondensate state in 20Ne

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Nuclear Science and Techniques 2024年第2期35卷 3-5页

作者： Takahiro kawabata Department of Physics Osaka UniversityToyonakaOsaka 560-0043Japan

Theclustering phenomenon,in which nucleons are arranged intoparticles(4 He nuclei)within a nuclear system,is one of the most intriguing aspects of nuclear *** has been observed in various light nuclei,such as^(8)Be,^(12)C,^(16)O,and^(20)Ne,and is responsible for many exotic and fascinating phenomena,such as the Hoyle state in^(12)C,which plays an essential role in stellar nucleosynthesis[1-6]as well as in heavy-ion collisions[7-9].

关键词： structure state

Perspective on the practical indications of endoscopic submucosal dissection of gastrointestinal neoplasms

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World Journal of Gastroenterology 2008年第27期14卷 4289-4295页

作者： mitsuhiro Fujishiro Department of Gastroenterology Graduate School of Medicine The University of Tokyo

Endoscopic submucosal dissection (ESD) is a new endoluminal therapeutic technique involving the use of cutting devices to permit a larger resection of the tissue over the muscularis propria. The major advantages of the technique in comparison with polypectomy and endoscopic mucosal resection are controllable resection size and shape and en bloc resection of a large lesion or a lesion with ulcerative findings. This technique is applied for the endoscopic treatment of epithelial neoplasms in the gastrointestinal tract from the pharynx to the rectum. Furthermore, some carcinoids and submucosal tumors in the gastrointestinal tract are treated by ESD. To determine the indication, two aspects should be considered. The first is a little likelihood of lymph node metastasis and the second is the technical resectability. In this review, practical guidelines of ESD for the gastrointestinal neoplasms are discussed based on the evidence found in the literature.

关键词： Endoscopic submucosal dissection Endoscopic mucosal resection Gastrointestinal neoplasm Treatment guideline Lymph node metastasis

Effects of loading contact on electric-power generation of lead zirconate titanate piezoelectric ceramic plate

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Journal of Advanced Ceramics 2019年第4期8卷 509-518页

作者： mitsuhiro OKAYASU Tsukasa OGAWA Graduate School of Natural Science and Technology Okayama University

To better understand the generation of electric power for piezoelectric Pb Zr Ti O3(PZT)ceramic plate(?25 mm),an attempt was made to investigate experimentally and numerically electricpower generation characteristics during cyclic bending under various loading fixtures(?0–?20 mm),i.e.,different contact *** the load-contact area on the PZT ceramic leads to a nonlinear decrease in the generated *** contact area basically enhances the generated voltage,although the voltage saturates during loading when the contact area is less than?5 mm.A similar voltage is generated for?0 and?5 mm,which is attributed to strain status(ratio of compressive and tensile strain)and material failure due to different stress distribution in the PZT *** the basis of the obtained electric generation voltage,suitable loading conditions are clarified by loading with the?5 mm fixture,which generates a higher voltage and a longer lifetime of the PZT *** this approach,it is appeared that the area contact with the area ratio of 0.04(?5 mm/?20 mm)is suitable to obtain the high efficiency of the electric voltage.

关键词： piezoelectric ceramic lead zirconate titanate ceramic electric power generation

The future of bone marrow stromal cell transplantation for the treatment of spinal cord injury

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Neural Regeneration Research 2015年第3期10卷 383-384页

作者： mitsuhiro Enomoto Department of Orthopaedic and Spinal Surgery Graduate SchoolTokyo Medical and Dental University Hyperbaric Medical Center Tokyo Medical and Dental University

Bone marrow stromal cell （BMSC） transplantation therapy is a promising approach for treating spinal cord injury （SCI）, based on a number of experimental and clinical reports （Wright et al., 2011）. BMSCs are a source of neuroregenerative somatic stem cells that are without the potential for tumorigenicity. Although clinical studies of autologous BMSC transplantation have been reported in Asia （fiang et al., 2013; Yoon et al., 2007）, in Japan, it is currently an uncommon procedure and highly controversial as well. This perspective paper provides an overview of the clinical effectiveness of BMSC trans- 191antation and a proposal to enhance its use as a viable therapy.

关键词： BMSCs The future of bone marrow stromal cell transplantation for the treatment of spinal cord injury SCI bone cell

Role of acetyl group on proton conductivity in chitin system

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Journal of Materiomics 2019年第2期5卷 258-263页

作者： Takashi kawabata Yasumitsu Matsuo Department of Life Science Faculty of Science&EngineeringSetsunan University17-8 Ikeda-nakamachiNeyagawaOsaka572-8508Japan

Measurements of proton conductivity in chitin and chitosan have been carried out and proton conductivity is *** the measurement of fuel cell based on the deacetylated chitin(chitosan)electrolyte,it was found that chitosan becomes the electrolyte of fuel *** result indicates that chitosan in humidified condition exhibits proton conductivity as seen in ***,proton conductivity in chitin is about 100 times higher than that in *** results indicate that acetyl group is an important factor for the appearance of higher proton conductivity in chitin *** addition,the anisotropy of proton conductivity in chitosan is much larger than that in the orientated *** that proton conductivity is caused by proton transfer in water bridges,these results indicate that chitin and chitosan possess quasi-three dimensional water bridges and quasi-two dimensional water bridges,*** is deduced from these results that acetyl group is a key factor not only the appearance of higher proton conductivity but also the realization of quasi-three dimensional proton conductivity.

关键词： Fuel cell Electrolyte Biomaterial and proton conductor

Novel image-enhanced endoscopy with i-scan technology

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World Journal of Gastroenterology 2010年第9期16卷 1043-1049页

作者： Shinya Kodashima mitsuhiro Fujishiro Department of Endoscopy and Endoscopic Surgery Graduate School of MedicineThe University of Tokyo

i-scan technology is the newly developed imageenhanced endoscopy technology from PENTAX,*** consists of three types of algorithms:surface enhancement (SE),contrast enhancement (CE),and tone enhancement (TE).SE enhances light-dark contrast by obtaining luminance intensity data for each pixel and applying an algorithm that allows detailed observation of a mucosal surface *** digitally adds blue color in relatively dark areas,by obtaining luminance intensity data for each pixel and applying an algorithm that allows detailed observation of subtle irregularities around the *** enhancement functions work in real time without impairing the original color of the organ,therefore,SE and CE are suitable for screening endoscopy to detect gastrointestinal tumors at an early *** dissects and analyzes the individual RGB components of a normal *** algorithm then alters the color frequencies of each component and recombines the components to a single,new color *** is designed to enhance minute mucosal structures and subtle changes in *** works in real time and consists of three modes such as TE-g for gastric tumors,TE-c for colonic tumors,and TE-e for esophageal *** is suitable mainly for detailed examination of the lesions that are detected in a screening endoscopy.i-scan technology leads us to easier detection,diagnosis and treatment of gastroi ntestinal diseases.

关键词： Gastrointestinal tumor Gastrointestinal endoscopy

Endoscopic submucosal dissection for stomach neoplasms

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World Journal of Gastroenterology 2006年第32期12卷 5108-5112页

作者： mitsuhiro Fujishiro Department of Gastroenterology Graduate School of Medicine University of Tokyo7-3-1HongoBunkyokuTokyoJapan

Recent advances in techniques of therapeutic endoscopy for stomach neoplasms are rapidly achieved. One of the major topics in this field is endoscopic submucosal dissection （ESD）. ESD is a new endoscopic technique using cutting devices to remove the tumor by the following three steps： injecting fluid into the submucosa to elevate the tumor from the muscle layer, pre-cutting the surrounding mucosa of the tumor, and dissecting the connective tissue of the submucosa beneath the tumor. So the tumors are resectable in an en bloc fashion, regardless of the size, shape, coexisting ulcer, and location. Indication for ESD is strictly confined by two aspects： the possibility of nodal metastases and technical difficulty, which depends on the operators. Although long-term outcome data are still lacking, short-term outcomes of ESD are extremely favourable and laparotomy with gastrectomy is replaced with ESD in some parts of therapeutic strategy for early gastric cancer.

关键词： Therapeutic endoscopy Endoscopicsubmucosal dissection Stomach neoplasia Early cancer Node-negative tumor

Precise analysis of compressive strain effects on electric power generation properties of a lead zirconate titanate piezoelectric ceramic

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Journal of Advanced Ceramics 2016年第1期5卷 35-39页

作者： mitsuhiro OKAYASU Keisuke WATANABE Graduate School of Natural Science and Technology Okayama University 3-1-1 Tsushimanaka Kita-kuOkayama 700-8530 Japan Graduate School of Science and Engineering Ehime University 3 Bunkyo-cho MatsuyamaEhime 790-8577 Japan

Electric power generation characteristics of lead zirconate titanate (PZT) piezoelectric ceramic have been examined during cyclic loading with different compressive strain value. A thin PZT ceramic plate attached to a thin brass plate was used. With an increasing compressive strain value in the PZT ceramic plate, the electric voltage increased, and the highest electric voltage was obtained for the sample with the high strain level (0.4%). The electric voltage decreased for the sample with more than 0.45% strain because of the failure in the PZT ceramic. The electric voltage was different depending on the strain condition, where the higher strain and the wider strain range (Δε) made the high electric voltage. Moreover, the electric voltage was attributed to the strain rate, where the higher strain rate made higher electric voltage due to high kinetic energy. The electric generation characteristics could be estimated with an operation of the strain value and strain ratio (εmin/εmax) especially for the sample loaded cyclically under the slow loading speed. This was affected by the linear correlation between the electric voltage and the strain value. Based upon the experimental work, suitable loading condition to make high electric voltage could be proposed.

关键词： energy harvesting piezoelectric ceramic cyclic loading electric power generation

Novel aspects of extracellular adenosine dynamics revealed by adenosine sensor cells

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Neural Regeneration Research 2017年第6期12卷 881-885页

作者： Kunihiko Yamashiro mitsuhiro Morita Department of Biochemistry and Cellular Biology National Institute of Neuroscience National Center of Neurology and Psychiatry (NCNP) Department of NCNP Brain Physiology and Pathology Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Department of Biology Kobe University Graduate School of Sciences

Adenosine modulates diverse physiological and pathological processes in the brain, including neuronal activities, blood flow, and inflammation. However, the mechanisms underlying the dynamics of extracellular adenosine are not fully understood. We have recently developed a novel biosensor, called an adenosine sensor cell, and we have characterized the neuronal and astrocytic pathways for elevating extracellular adenosine. In this review, the physiological implications and therapeutic potential of the pathways revealed by the adenosine sensor cells are discussed. We propose that the multiple pathways regulating extracellular adenosine allow for the diverse functions of this neuromodulator, and their malfunctions cause various neurological and psychiatric disorders.

关键词： adenosine neuronal physiological understood astrocyte neurological Adenosine synaptic hippocampal psychiatric