The future of bone marrow stromal cell transplantation for the treatment of spinal cord injury

作     者：Mitsuhiro Enomoto 

作者机构：Department of Orthopaedic and Spinal SurgeryGraduate SchoolTokyo Medical and Dental University Hyperbaric Medical CenterTokyo Medical and Dental University 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2015年第10卷第3期

页      面：383-384页

核心收录：

学科分类：0710[理学-生物学] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

基　　金：supported in part by the Ministry of Health,Labour and Welfare Sciences Research Grant a Grant-in-Aid for Scientific Research(C)from the Japan Society for the Promotion of Science a Grant-in-Aid from the General Insurance Association of Japan 

主　　题：BMSCs The future of bone marrow stromal cell transplantation for the treatment of spinal cord injury SCI bone cell 

摘      要：Bone marrow stromal cell （BMSC） transplantation therapy is a promising approach for treating spinal cord injury （SCI）, based on a number of experimental and clinical reports （Wright et al., 2011）. BMSCs are a source of neuroregenerative somatic stem cells that are without the potential for tumorigenicity. Although clinical studies of autologous BMSC transplantation have been reported in Asia （fiang et al., 2013; Yoon et al., 2007）, in Japan, it is currently an uncommon procedure and highly controversial as well. This perspective paper provides an overview of the clinical effectiveness of BMSC trans- 191antation and a proposal to enhance its use as a viable therapy.