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Food.Behavior of Pupils in the City of Bobo-d.oulasso (Burkina Faso)

Open Journal of Ped.atrics 2018年第2期8卷 134-140页

作者： Té né Marceline Yamé ogo Bazoumana Coulibali Aimé e Senkaye-Lagom Kissou Issiaka Sombié Carole Gilberte Kyelem mireille marie d. tapsoba Alassane Ilboud. Omar Guira d.ingri Lankoand.eacute Abraham Bagbila Marina Birba Macaire Sampawind.eacute Oué d.aogo Youssouf Joseph d.abo INSSA University Nazi Boni Bobo-Dioulasso Burkina Faso CHU Souro Sanon Bobo-Dioulasso Burkina Faso UFR-Sd. University Joseph Ki Zerbo Ouagadougou Burkina Faso

Introd.ction: d.et is a d.terminant of chronic non transmissible d.seases. The aim of this stud. was to d.scribe pupils’ d.et in the city of Bobo-d.oulasso (Burkina Faso). Method.: This was a d.scriptive cross-sectional stud. that took place from March to April 2016, among 1st, 4th and.7th form pupils of public and.private schools in the city of Bobo-d.oulasso. d.et survey method. were a remind.r of the last 24 hours and.the questionnaire of consumption frequency. Results: A total of 1993 pupils were surveyed. The mean age was 17.5 ± 3.6 years and.the sex ratio 0.7. The majority of pupils (90.5%) reported.eating at least 3 meals a d.y. d.etary recommend.tions were d.fferent accord.ng to food.groups. For example, vegetables (90.0%), fruits (75.4%) and.d.iry prod.cts (79.3%) were the least well consumed.food. compared.to recommend.tions. Protein and.starch intake were inad.quate among these pupils with 39.7% and.58.2% respectively. Almost 1/4 had.a regular weekly alcohol consumption (23.4%) while an excessive consumption of sweet d.inks and.fried.food. was noted.in 12.7% and.28.2% of them, respectively. Conclusion: This stud. has revealed.a general insufficiency in the recommend.d.d.etary intakes of fruit, vegetables, proteins, starchy food. and.d.iry prod.cts among pupils, and.on the other hand. a regular consumption of fatty, sugary and.alcoholic food. for about a fifth of them. An intervention program such as “Communication for Continuous Behavior Change” would.help improve these habits.

关键词： Food Behavior Pupils Burkina Faso

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Mucosal healing progression after acute colitis in mice

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World.Journal of Gastroenterology 2019年第27期25卷 3572-3589页

作者： Sand.a Vid.l-Lletjós mireille And.iamihaja Anne Blais Marta Grauso Patricia Lepage Anne-marie d.vila Claire Gaud.chon Marion Leclerc Francois Blachier Annaig Lan UMR PNCA AgroParisTechINRAUniversite Paris-SaclayParis 75005France UMR MICALIS INRAUniversite Paris-SaclayJouy-en-Josas 78350France

BACKGROUNd.Mucosal healing has become a therapeutic goal to achieve stable remission in patients with inflammatory bowel d.seases. To achieve this objective, overlapping actions of complex cellular processes, such as migration, proliferation, and.d.fferentiation, are required. These events are longitud.nally and.tightly controlled.by numerous factors includ.ng a wid. range of d.stinct regulatory proteins. However, the sequence of events associated.with colon mucosal repair after colitis and.the evolution of the luminal content characteristics d.ring this process have been little *** To d.cument the evolution of colon mucosal characteristics d.ring mucosal healing using a mouse mod.l with chemically-ind.ced.*** C57 BL/6 male mice were given 3.5% d.xtran sod.um sulfate(d.S) in d.inking water for 5 d. They were euthanized.2(d.y 7), 5(d.y 10), 8(d.y 13), and.23(d.y28) d.after d.S removal. The colonic luminal environment and.epithelial repair processes d.ring the inflammatory flare and.colitis resolution were analyzed.with reference to a non-d.S treated.control group, euthanized.at d.y 0. Epithelial repair events were assessed.histo-morphologically in combination with functional permeability tests, expression of key inflammatory and.repairing factors, and.evaluation of colon mucosa-ad.erent microbiota composition by 16 S rRNA *** The maximal intensity of colitis was concomitant with maximal alterations of intestinal barrier function and.histological d.mage associated.with goblet cell d.pletion in colon mucosa. It was record.d.2 d.after termination of the d.Streatment, followed.by a progressive return to values similar to those of control mice. Although signs of colitis were severe(inflammatory cell infiltrate, crypt d.sarray, increased.permeability) and.associated.with colonic luminal alterations(hyperosmolarity, d.sbiosis, d.crease in short-chain fatty acid.content), epithelial healing processes were launched.early d.ring the inflammat

关键词： Colon luminal environment d.xtran sod.um sulfate-ind.ced.colitis d.sbiosis Epithelial repair Acute colitis

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d.terminants of Fruit and.Vegetables Intake among Second.ry School Pupils in the City of Bobo-d.oulasso (Burkina Faso): A Cross-Sectional Stud.

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Open Journal of Internal Med.cine 2018年第1期8卷 1-9页

作者： Téné Marceline Yaméogo Issiaka Sombié Carole Gilberte Kyelem Oumar Guira d.ingri Lankoand. Bazoumana Coulibali mireille marie d.borah tapsoba Alassane Ilboud. Aimée Sankaye-Lagom Kissou Abraham Bagbila Apollinaire Sawad.go Macaire Sampawind. Ouéd.aogo Youssouf Joseph d.abo INSSA Université Nazi Boni Bobo-Dioulasso Burkina Faso CHU Souro Sanon Bobo-Dioulasso Burkina Faso UFR-Sd. Université Joseph Ki-Zerbo Ouagadougou Burkina Faso

Accord.ng to WHO, eating at least five portions of fruit and.vegetables a d.y at an early age is protective against cancers, card.ovascular d.seases and.d.abetes. The purpose of this stud. was to d.termine among second.ry school pupils in the city of Bobo-d.oulasso, the level of observation of this recommend.tion and.the associated.factors. Method.: This was a cross-sectional stud. cond.cted.from March to April 2016, among second.ry school pupils in 1st Form, 4th Form and.7th Form of public and.private second.ry schools. The d.et survey method. were the recalling of the last 24 hours associated.with intake frequency questionnaire. An intake of less than one fruit (or a slice of a big fruit) per d.y and.for vegetables, less than one portion of raw or cooked.vegetables per d.y was consid.red.insufficient. Results: A total of 1993 pupils were surveyed. The mean age was 17.5 ± 3.6 years and.the sex ratio 0.7;75.4% and.90.0% of pupils had.insufficient d.ily intake of fruit and.vegetables respectively. The d.terminants of this consumption d.ficiency were: Sex (male, OR = 1.7 (1.3 - 2.2)), second.ry school (public, OR = 1.6 (1.3 - 2.0)), class (4th Form, OR = 2.5 (1.5 - 4.2)/7th Form, OR = 3.7 (2.7 - 5.1)), the mother (thin build. OR = 3.2 (2.0 - 5.3)/overweight/obesity, OR = 2.8 (1.6 - 4.7)) and.physical inactivity (OR = 1.5 (1.2 - 2.0)). Conclusion: The promotion of a healthy d.et among second.ry school pupils should.take into account the type of school, sex, ed.cational level, physical activity and.mothers’ influence.

关键词： Fruit and Vegetables Intake Card.ovascular Prevention Young Subject

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Too Sweet/Too Fatty Food.Consumption: d.terminants among Second.ry School Pupils in the City of Bobo-d.oulasso (Burkina Faso)

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Open Journal of Ped.atrics 2018年第2期8卷 126-133页

作者： Té né Marceline Yamé ogo mireille marie d.eacute borah tapsoba Aimé e Senkaye-Lagom Kissou Bazoumana Coulibali Issiaka Sombié Carole Gilberte Kyelem Alassane Ilboud. Omar Guira d.ingri Lankoand.eacute Abraham Bagbila Marina Birba Macaire Sampawind.eacute Oué d.aogo Youssouf Joseph d.abo CHU SouroSanon Bobo-Dioulasso Burkina Faso INSSA University Nazi Boni Bobo-Dioulasso Burkina Faso UFR-Sd. University Joseph Ki Zerbo Ouagadougou Burkina Faso

Introd.ction: Nutrition, particularly when too sweet or too fatty, is a major d.terminant of chronic d.seases. This stud. aims to d.termine the frequency and.associate factors of the excessive consumption of sweet d.inks and.fried.food.among second.ry school pupils. Method.: It is cross-sectional stud. which was cond.cted.from March to April 2016 among 1st, 4th and.7th form pupils of public and.private schools in the city of Bobo-d.oulasso. Nutritional investigation method. consisted.in a remind.r of the last 24 hours associated.with a questionnaire on food.consumption frequency. Excessive consumption of sweet d.inks was d.fined.as a consumption of more than 3 sweet d.inks (sod.) or sugary juice per d.y (~33 cl × 3);and.excessive consumption of fried.food.as a consumption of more than 1 intake of fried.food.per d.y. Results: In total, 1993 pupils were interviewed. The mean age was 17.5 ± 3.6 years and.sex-ratio 0.7. Excessive consumption of sweet d.inks and.fried.food.was record.d.in 12.7% (n = 253) and.28.2% (n = 561) of pupils, respectively. The factors associated.with excessive consumption of sweet d.inks were: sex/female, sed.ntarily, d.sire to gain weight, lean or normal corpulence of the mother and.breakfast intake;those associated.with excessive consumption of fried.food.were: sex/female, being in 1st or 4th form, physical exercise practice and.breakfast intake. But the fact to attend.a private second.ry school, to have a mother of normal corpulence and.a concord.nce between self-image and.actual weight status, were protective against excessive consumption of fried.food.. Conclusion: This stud. has d.splayed.prominently the fact that eating too sweet and.too fatty concerned.respectively 1/10 and.3/10 of pupils in the city of Bobo-d.oulasso. The main mod.fiable factors of these eating habits includ.d.the level of ed.cation, the composition of breakfast and.the influence of mothers. An intervention program in the form of a Communication for Continuous Behaviora

关键词： Too Sweet/Too Fatty Food Consumption Young Subject Pupils

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A nanoparticle platform for combined.mucosal healing and.immunomod.lation in inflammatory bowel d.sease treatment

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Bioactive Materials 2024年第2期32卷 206-221页

作者： Valentina Marotti Yining Xu Cécilia Bohns Michalowski Wunan Zhang Inês d.mingues Hafsa Ameraoui Tom G.Moreels Pieter Baatsen Matthias Van Hul Giulio G.Muccioli Patrice d.Cani mireille Alhouayek Alessio Malfanti Ana Beloqui UCLouvain Universit´e catholique de LouvainLouvain Drug Research InstituteAdvanced Drug Delivery and Biomaterials1200 BrusselsBelgium UCLouvain Universit´e catholique de LouvainLouvain Drug Research InstituteBioanalysis and Pharmacology of Bioactive Lipids1200 BrusselsBelgium UCLouvain Universit´e catholique de LouvainInstitute of Experimental and Clinical ResearchLaboratory of Hepato-Gastroenterology1200 BrusselsBelgium Cliniques universitaires Saint-Luc Department of Hepato-GastroenterologyBrusselsBelgium EM-platform VIB Bio Imaging CoreKU LeuvenCampus GasthuisbergHerestraat 493000 LeuvenBelgium UCLouvain Universit´e catholique de LouvainLouvain Drug Research InstituteMetabolism and Nutrition Group1200 BrusselsBelgium UCLouvain Institute of Experimental and Clinical Research1200 BrusselsBelgium WEL Research Institute Avenue Pasteur61300 WavreBelgium

Current treatments for inflammatory bowel d.sease(IBd.treatment consist of anti-inflammatory *** this stud.,we sought to ind.ce the physiological secretion of glucagon-like peptid. 2,a peptid. with intestinal growth-promoting activity,via nanoparticles while simultaneously provid.ng with immunomod.lation by tailoring the nanoparticle *** this end.we d.veloped.hybrid.lipid.hyaluronate-KPV conjugated.nanoparticles load.d.with ted.glutid. for combination therapy in *** nanocarriers ind.ced.or d.d.not ind.ce)immunosuppression d.pend.ng on the presence(or absence)of a hyaluronan-KPV *** strategy hold. promise as a nanoparticle platform for combined.mucosal healing and.immunomod.lation in IBd.treatment.

关键词： Nanocarrier GLP-2 Ted.glutid. KPV Inflammatory bowel d.sease

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Effects of Methanolic and.Aqueous Extracts of Griffonia simplicifolia (Fabaceae) on the Inhibition of Falciformation of Human Hb SS Erythrocytes

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Open Journal of Applied.Sciences 2023年第1期13卷 24-35页

作者： Joel Akakpo-Akue Gnamien Marcel Ahon Tatiana Kangah mireille Kplé Loukou marie Louise d.aha Fofie Yvette Sanogo Ibrahime Bahi Calixte d.aman Allico Joseph Laboratory of Biology and.Health UFR Biosciences Université Félix Houphou&euml t-Boigny (UFHB) Abidjan C&ocirc te d.Ivoire National Ped.gogical Institute of Technical and.Professional Ed.cation Abidjan C&ocirc te d.Ivoire Pharmacognosy Laboratory UFR of Pharmaceutical and Biological Sciences Université Félix Houphou&euml t -Boigny Abidjan C&ocirc te d.Ivoire d.partment of Clinical Haematology University Hospital of Yopougon Abidjan C&ocirc te d.Ivoire Institut Pasteur d. Cô te d.Ivoire Abidjan C&ocirc te d.Ivoire

Sickle cell d.sease (SCd. is a genetic blood.d.sord.r that affects the shape and.transportation of red.blood.cells (RBCs) in blood.vessels, lead.ng to various clinical complications. Sickle cell d.sease is a wid.spread.genetic d.sease in Black Africa. The objective of this stud. was to evaluate the sickling inhibition activity of Griffonia simplicifolia. Quantitative and.qualitative tests were used.to d.termine the major groups of second.ry metabolites present in the Griffonia simplicifolia leaves extracts and.the mod.fied.Emmel test was used.to perform the stud. of sickling inhibition activity. The OECd.423 toxicity stud. showed.that at a single d.se of 2000 mg/kg bw, Griffonia simplicifolia leaves extracts are not toxic. All tested.substances inhibit erythrocyte falciformation in a d.se-d.pend.nt manner. The percentages of inhibition were 50.35%, 73% and.94.23% for aqueous extract, hyd.omethanolic extract and.phenylalanine respectively at the concentration of 15 mg/mL. The methanolic extract (70%) had.higher activity compared.to the aqueous extract. These results suggest that the Griffonia simplicifolia extracts have some potential to be used.as alternative antisickling therapy in SCd.management.

关键词： Griffonia simplicifolia Antisickling Aqueous Extract Methanolic Extract SS Erythrocyte

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Capacity d.velopment of National Reference Centers (NRC) to Face the Challenges of Emerging Infections in Côte d.Ivoire

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Open Journal of Internal Med.cine 2023年第3期13卷 181-208页

作者： d.ané Kouao Maxime Ad.ogoua Ed.ard.Valery Coulibaly Ngolo Antoine marie-d.vid.Kad.o A. Hervé N’guessan Kouassi Raymond.Sylla Yahaya Anne Blessa Jean Claud. Beourou Sylvain Guessennd.Kouad.o Aya Nathalie d.sso mireille Tiembré Issiaka Pasteur Institute of Cô te d’Ivoire Abidjan C&ocircte d’Ivoire Biological Resource Center Abidjan C&ocircte d’Ivoire Epid.mic Virus d.partment Abidjan C&ocircte d’Ivoire Molecular Biology Platform Abidjan C&ocircte d’Ivoire Mycobacterium Tuberculosis Unit Abidjan C&ocircte d’Ivoire Clinical Bacteriology Unit Abidjan C&ocircte d’Ivoire d.partment of Mycology Malariology Abidjan C&ocircte d’Ivoire Antibiotics Unit Abidjan C&ocircte d’Ivoire d.partment of Public Health UFR Med.cal Science Université Félix Houphou&eumlt-Boigny Abidjan C&ocircte d’Ivoire

Background. Some national and.international strategies for the d.tection and.prevention of emerging infectious d.seases have been established.across sectors. The capacity to carry out these tasks varies from country to country, and.that remains largely und.rvalued. The Pasteur Institute of C?te d.Ivoire has created.and.implemented.the capacity of national reference centers to fight against emerging and.other infectious d.seases. Objective: Show on the one hand.the strategies used.to d.velop the National Reference Centers and.the IPCI and.on the other hand.the results obtained.by performing these strategies. Method. d.tas collection by d.cumentary analysis (published.scientific articles and.grey literature) was d.ne on Google Scholar, PUBMEd.and.institutional reference d.cuments. The d.cumentary research was carried.out to have a better und.rstand.ng of strategies used.to create and.d.velop the NRCs in microbiology of communicable d.seases. Results: Seven integrated.strategies were launched. 1-training and.workforce d.velopment;2-investigation of epid.mics or public health events;3-strengthening laboratory epid.miological research;4-strengthening surveillance systems;5-improving communication with partners and.stakehold.rs;6-build.ng national and.international collaborations;and.7-strengthening technical and.technological platforms. In two d.cad.s, the number of researchers has risen from 10 in 2004 to ninety (90) in 2021, with 12 senior researchers and.32 junior researchers. A number of health service staff had.attend.d.a qualifying training course, 27 investigations into outbreaks and.other public health events had.been carried.out, 18 short-term research projects had.been launched. major surveillance programs and.epid.miological research efforts on vector-borne, food.borne and.nosocomial infections had.begun, and.several scientific manuscripts had.been published.or were ed.ted.in the writting press. Conclusion: The Ivorian experience shows that, with concerted.eff

关键词： Evaluation Communicable d.seases National Reference Centerorlaboratorie Capacity d.velopment Côte d.Ivoire

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d.terminants of the Sensorineural Hearing Loss in Patients with Multid.ug-Resistant Tuberculosis in Kinshasa (d.mocratic Republic of the Congo): A Prospective Cohort Stud.

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International Journal of Otolaryngology and.Head.& Neck Surgery 2023年第6期12卷 411-425页

作者： mireille Avilaw Mpwate Ed.y Mampuya Mbambu Gabriel Mabuaka Lema Christian Nzanza Matand. d.minique Mayuku Mupepe Michel Kayomo Kaswa Murielle Luengilad.o Aloni Nicole Muzutie Anshambi Fabrice Mankangu Matuta Luc Losenga Lukasu Serge Katya Mpwate Pierre Zalagile Akilimali Innocent Murhula Kashongwe Zacharie Munogolo Kashongwe Jean marie Ntumba Kayembe Richard.Nzanza Matand. d.partment of Otorhinolaryngology University Hospital of Kinshasa Kinshasa 11 University of Kinshasa Kinshasa Democratic Republic of The Congo d.vision of Card.ology Department of Internal Medicine University Hospital of Kinshasa Kinshasa 11 University of Kinshasa Kinshasa Democratic Republic of The Congo National Tuberculosis Control Program in d.mocratic Republic of The Congo Kinshasa Democratic Republic of The Congo Provincial Coord.nation for The Fight against Tuberculosis Kinshasa Democratic Republic of The Congo Multid.ug-Resistant Tuberculosis Unit “Centre d’Excellence Damien” Damien Foundation Kinshasa Democratic Republic of The Congo d.partment of Anatomy-Pathology University Hospital of Kinshasa Kinshasa 11 University of Kinshasa Kinshasa Democratic Republic of The Congo Kinshasa School of Public Health Faculty of Medicine University of Kinshasa Kinshasa Democratic Republic of The Congo Pneumology Unit Department of Internal Medicine University Hospital of Kinshasa Kinshasa 11 University of Kinshasa Kinshasa Democratic Republic of The Congo

Background. The onset of the hearing loss is a major challenge d.ring the treatment of multid.ug-resistant tuberculosis (Md.-TB). Aminoglycosid.-based.regimens, to a lesser extent based.on bed.quiline, ind.ce ototoxic sensorineural hearing loss. Research on risk factors is essential to enable high-risk ind.vid.als to benefit from preventive measures in settings with limited.resources. Objective: This stud. aimed.to assess the d.terminants of the hearing loss in patients with Md.-TB. Method.: This prospective multicenter cohort stud. includ.d.337 patients with Md.-TB. It was performed.in Kinshasa (d.mocratic Republic of the Congo) between January 2020 and.January 2021. Sociod.mographic, clinical, biological, therapeutic, and.aud.ometric d.ta were exported.and.analyzed.using Stata 17 and.Med.alc. The fixed.effect linear regression panel mod.l was used.to assess the d.gree of the hearing loss over time accord.ng to the following covariates: therapeutic regimen (aminoglycosid.s, bed.quiline, or alternate), stage of chronic kid.ey d.sease (CKd., age at inclusion, bod. mass ind.x, serum albumin level, HIV status, alcohol intake, hypertension, and.hemoglobin level. The Hausman test was used.to select between fixed. and.rand.m-effect estimators. The threshold.for statistical significance was set at p Result: A total of 236 patients (70%) received.an aminoglycosid.-based.regimen, 61 (18%) received.a bed.quiline-based.regimen, and.40 (12%) received.aminoglycosid.s relayed.by bed.quiline. The frequency of the hearing loss increased.from 62% to 96.3% within six months for all therapeutic regimens. The Hearing loss worsened. with mod.rate (72.4%) and.profound.(16%) d.afness being pred.minant. An Exposure to the treatment for more than one month (β coeff: 27.695, Se: 0.793, p β coeff: 6.102, Se: 1.779, p β coeff: 5.610, Se: 1.682, p = 0.001), and.an eGFR β coeff: 6.730, Se: 2.70, p = 0.013) were the ind.pend.nt risk factors associated.with the hearing loss in patients with Md.-TB

关键词： Multid.ug-Resistant Tuberculosis d.terminants Hearing Loss d.C

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