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Acut. myelogenous leukemia and acut. leukemic appendicit.s:A case report

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World Journal of Gast.oent.rology 2009年第44期15卷 5624-5625页

作者： Po-Jen Hsiao Shih-ming kuo Jia-Hong Chen Hsuen-Fu Lin Pau-Ling Chu Shih-Hua Lin ching-Liang Ho Depart.ent.of Int.rnal Medicine Tri-Service General Hospital National Defense Medical Center 114 Taipei Taiwan China Division of Pediat.ic Surgery Department of Surgery Tri-Service General Hospital National Defense Medical Center 114 Taipei Taiwan China Division of Hemat.logy/Oncology Department of Internal Medicine Tri-Service General Hospital National Defense Medical Center 114 Taipei Taiwan China

Acut. myelogenous leukemia(AML)can involve t.e gast.oint.st.nal t.act.but.rarely involves t.e appendix. We report.a male pat.ent.who had 1 year part.al remission from AML and who present.d wit. apparent.acut. appendicit.s as t.e init.al manifest.t.on of leu-kemia *** findings of t.e appendix revealed t.ansmural infilt.at.s of myeloblast.,which indicat.d a diagnosis of ***,t.e pat.ent.died from progression of t.e disease on t.e 19t. d aft.r *** leukemic cell infilt.at.on of t.e appendix is uncommon,pat.ent. wit. leu-kemia relapse can present.wit. sympt.ms mimicking acut. appendicit.s.

关键词： Acut. myeloid leukemia Appendicit.s Appendect.my Granulocyt.c sarcoma

t.n- year follow- up invest.gat.on of st.oke risk in syst.mic lupus eryt.emat.sus

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St.oke & Vascular Neurology 2024年第1期9卷 1-7页

作者： Jin-An Huang ching-Heng Lin ming-Ju Wu Yi-Hsing Chen kuo-Cheng Chang Chung-Wei Hou Division of Neurology Neurological InstituteTaichung Veterans General HospitalTaichungTaiwanChina Depart.ent.of Healt. Business Administ.at.on Hungkuang UniversityTaichungTaiwanChina Depart.ent.of Medical Research Taichung Veterans General HospitalTaichungTaiwanChina Division of Nephrology Department of Internal MedicineTaichung Veterans General HospitalTaichungTaiwanChina School of Medicine Chung Shan Medical UniversityTaichungTaiwanChina College of Medicine Taiwan Chung Hsing UniversityTaichungTaiwanChina Division of Allergy Immunology and RheumatologyDepartment of Internal MedicineTaichung Veterans General HospitalTaichungTaiwanChina School of Medicine Taiwan Yang-Ming Chiao Tung UniversityTaichungTaiwanChina

Background and purpose t. analyse t.e long-t.rm risk of ischaemic st.oke and t.e clinical effect. of ant.t.rombot.cs on t.e risk of haemorrhagic st.oke in pat.ent. wit. syst.mic lupus eryt.emat.sus(SLE).Met.ods A ret.ospect.ve cohort.st.dy was conduct.d using a populat.on-based dat.base t.ken from t.iwan region Healt. Insurance Research *** wit. SLE bet.een 2000 and 2008 were regist.red and mat.hed wit. t.o cont.ols by t.e index dat.,age,gender and Charlson Comorbidit. Index(CCI).t.ese subject. were followed unt.l eit.er st.oke event.or 31 December *** HRs(aHRs)for st.okes were est.mat.d wit. Cox regression models,and t.e cumulat.ve incidence of ischaemic st.oke was analysed by log-rank t.st.and Kaplan-Meier survival *** In t.t.l,8310 pat.ent. wit. SLE and 16620 pat.ent. wit.out.SLE were *** general,pat.ent. wit. SLE had higher rat.s of ischaemic st.oke(5.4%vs 3.3%)and haemorrhagic st.oke(1.5%vs 0.6%)t.an in *** mult.variat. analysis adjust.d t. age,gender,CCI,urbanisat.on level and ant.t.rombot.cs uses,aHRs of all st.okes,ischaemic st.oke and haemorrhagic st.oke were 1.73(95%CI:1.54 t. 1.94),1.65(95%CI:1.45 t. 1.87)and 2.24(95%CI:1.71 t. 2.95),respect.vely,in pat.ent. wit. *** wit. SLE were significant.y more likely t. suffer ischaemic st.oke t.an pat.ent. wit.out.SLE,even 10 years aft.r SLE diagnosis(6.12%vs 3.50%,pt.plat.let.use increased t.e risk of haemorrhagic st.oke in SLE group(aHR=1.74,95%CI:1.18 t. 2.57).Conclusions Pat.ent. wit. SLE are at.great.r risk of developing ischaemic st.oke t.at.last. for 10 *** should be carefully administ.red t. prevent.cardiovascular event. in pat.ent. wit. SLE due t. t.e risk of haemorrhagic st.oke.

关键词： eryt.emat.sus diagnosis likely

Seismogenesis and occurrence of eart.quakes as observed by t.mporally cont.nuous gravit. variat.ons in China

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Chinese Science Bullet.n 1998年第1期43卷 8-21页

作者： Gongxu Gu John t. kuo Keren Liu Jinhan Zheng Hongyan Lu Duanfa Liu St.t. Seismol Bur Inst Geophys Beijing 100081 Peoples R China Columbia Univ Lamont Doherty Earth Observ New York NY 10027 USA Columbia Univ Aldridge Lab Appl Geophys New York NY 10027 USA

In t.e last.decade and a half, a number of eart.quakes of magnit.de 4-5 have occurred in t.e Beijing_t.anjin_t.ngshan_Zhangjiakou (Bt.Z) region. On t.e basis of t.e analysis of t.e t.mporally cont.nuous gravit. variat.on dat. principally from t.e Baijiat.an (BJt.) semi_permanent.gravit. base st.t.on, a general pict.re of gravit. variat.on relat.d t. t.e seismogenesis and occurrence of eart.quakes has emerged.\;As gravit. variat.on is generally observed on t.e eart.’s surface, t.e predominant.influence is t.at.of t.e near_surface groundwat.r. t.e subsurface fluids are dist.ibut.d t.roughout.all dept.s in t.e crust.and respond t. t.e seismogenic processes of eart.quakes as well. t.e influence of t.e subsurface fluid on gravit. variat.on is, t.erefore, of equal import.nce. t.e fluids, which include t.e near_surface groundwat.r and t.e subsurface fluids dist.ibut.d t.roughout.all dept.s in t.e crust. play a more import.nt.role in t.e gravit. variat.ons in t.rms of t.e seismogenesis and occurrence of eart.quakes t.an previously realized.\;t.e abundance of accumulat.d dat. shows t.at.t.e dilat.ncy inst.bilit. (IPE) model seems not.applicable at.least.t. t.e seismogenesis and occurrence of eart.quakes in t.e Bt.Z region. In order t. reflect.t.e physical realit., t.e earlier proposed combined dilat.ncy model requires modificat.on. t.e seismogenic area in t.e Bt.Z region may be modelled as a large pre_st.essed volume of a fluid_filled poroelast.c medium, including not.only t.e pre_st.essed volume surrounding t.e impending rupt.re zone but.also t.e volume cont.ining t.e rupt.re of t.e fault.zone it.elf. t.e pre_st.essed volume out.ide t.e impending rupt.re zone is under a st.t. of relat.vely small change of t.e pre_exist.ng regional t.ct.nic st.ess, while t.e volume cont.ining t.e impending rupt.re zone is an induced region of very high local st.ess concent.at.on, and/or pore over_pressure.\;t.e calculat.d gravit. variat.ons based on t.e modified combined dilat.ncy model (MCD

关键词： gravit. variat.ons eart.quake groundwat.r subsurface fluids.

Mechanisms of Salt.t.lerance in t.ansgenic Arabidopsis t.aliana Carrying a Peroxisomal Ascorbat. Peroxidase Gene from Barley

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Pedosphere 2008年第4期18卷 486-495页

作者： XU Wei-Feng SHI Wei-ming A. UEDA t. t.KABE St.t. Key Laborat.ry of Soil and Sust.inable Agricult.re Institute of Soil Science Chinese Academy of Sciences Nanjing 210008 （China）. Graduat. School of t.e Chinese Academy of Sciences Beijing 100049 （China） Graduat. School of Bioagricult.ral Sciences Nagoya University Nagoya 464-8601 （Japan

Ascorbat. peroxidases （APX）, localized in t.e cyt.sol, peroxisome, mit.chondria, and chloroplast. of plant.cells, cat.lyze t.e reduct.on of H2O2 t. wat.r by using ascorbic acid as t.e specific elect.on donor. t. det.rmine t.e role of peroxisomal t.pe ascorbat. peroxidase （pAPX）, an ant.oxidant.enzyme, in prot.ct.on against.salt.induced oxidat.ve st.ess, t.ansgenic Arabidopsis t.aliana plant.carrying a pAPX gene （HvAPX1） from barley （Hordeum vulgat. L.） was analyzed. t.e t.ansgenic line pAPX3 was found t. be more t.lerant.t. salt.st.ess t.an t.e wild t.pe. Irrespect.ve of salt.st.ess, t.ere were no significant.differences in Na^＋, K^＋, Ca^2＋, and Mg^2＋ cont.nt. and t.e rat.o of K^＋ t. Na^＋ bet.een pAPX3 and t.e wild t.pe. Clearly, t.e salt.t.lerance in pAPX3 was not.due t. t.e maint.nance and reest.blishment.of cellular ion homeost.sis. However, t.e degree of H2O2 and lipid peroxidat.on （measured as t.e levels of malondialdehyde） accumulat.on under salt.st.ess was higher in t.e wild t.pe t.an in pAPX3. t.e mechanism of salt.t.lerance in t.ansgenic pAPX3 can t.us be explained by reduct.on of oxidat.ve st.ess injury. Under all condit.ons t.st.d, act.vit.es of superoxide, glut.t.ione reduct.se, and cat.lase were not.significant.y different.bet.een pAPX3 and t.e wild t.pe. In cont.ast. t.e act.vit. of APX was significant.y higher in t.e t.ansgenic plant.t.an in wild t.pe under salt.st.ess. t.ese result. suggest.d t.at.in higher plant., HvAPX1 played an import.nt.role in salt.t.lerance and was a candidat. gene for developing salt.olerant.crop plant..

关键词： ascorbat. peroxidase oxidat.ve st.ess peroxisome soil salinit. t.ansgenic Arabidopsis t.aliana

Composit.s of graphene and encapsulat.d silicon for pract.cally viable high-performance lit.ium-ion bat.eries

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Nano Research 2014年第10期7卷 1429-1438页

作者： Xin Zhao Minjie Li kuo-Hsin Chang Yu-ming Lin Bluest.ne Global t.ch 169 Myers Corners Road Wappingers Falls NY 12590 USA

A facile and scalable approach t. synt.esize silicon composit. anodes has been developed by encapsulat.ng Si part.cles via in sit. polymerizat.on and carbonizat.on of phloroglucinol-formaldehyde gel, followed by incorporat.on of graphene nanoplat.let.. As a result.of it. st.uct.ral int.grit., high packing densit. and an int.mat. elect.ical cont.ct.consolidat.d by t.e conduct.ve net.orks, t.e composit. anode yielded excellent.elect.ochemical performance in t.rms of charge st.rage capabilit., cycling life and coulombic efficiency. A half cell achieved reversible capacit.es of 1,600 mAh·g-1 and 1,000 mAh·g-1 at.0.5 A·g-1 and 2.1 A·g-1, respect.vely, while ret.ining more t.an 70% of t.e init.al capacit.es over 1,000 cycles. Complet. lit.ium-ion pouch cells coupling t.e anode wit. a lit.ium met.l oxide cat.ode demonst.at.d excellent.cycling performance and energy out.ut. represent.ng significant.advance in developing Si-based elect.ode for pract.cal applicat.on in high-performance lit.ium-ion bat.eries.

关键词： silicon nanopart.cles graphene nanoplat.let. phloroglucinol-formaldehyde gel lit.ium-ion bat.eries

Molecular dynamics simulat.on of ion select.vit. t.ait. of nickel hexacyanoferrat. t.in films

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中国有色金属学会会刊：英文版 2006年第4期16卷 897-902页

作者：郝晓刚 YU Qiu-ming JIANG Shao-yi D. t. SCHWARt. Depart.ent.of Chemical Engineering Taiyuan University of Technology Taiyuan 030024 China Depart.ent.of Chemical Engineering University of Washington Seattle Washington 98195-1750 USA

t.e ion select.vit. of nickel hexacyanoferrat. t.in film t. alkali cat.ons in ESIX (elect.ochemically swit.hed ion exchange) processes was invest.gat.d using molecular dynamics(MD) t.chniques; wat.r and cat.on (Na+ and Cs+) int.rcalat.on, configurat.on, and dynamics in reduced nickel hexacyanoferrat. st.uct.res wit. different.cat.on combinat.ons were st.died and compared wit. t.e experiment.l result.. In t.e simulat.ons, wat.r was represent.d by an ext.nded simple point.charge(SPC/E) model, and all ot.er at.mic int.ract.ons were represent.d by a universal force field(UFF). t.e pot.nt.al energies of various cat.ons combinat.on (Cs+ and Na+) in reduced i-NiHCF and 1 mol/L Cs/NaCl mixed solut.on were obt.ined. In most.cases, t.e t.t.l pot.nt.al energy of t.e solid is reduced when wat.r is int.rcalat.d int. t.e various reduced NiHCF st.uct.res. Combining t.e solid and t.e solut.on simulat.on result., it.is shown t.at.t.e solid composit.on of 3Cs+/1Na+ is t.e st.blest.st.uct.re form (NaCs3Ni4[Fe(CN)6]3) over a range of solut.on composit.ons.

关键词：镍分子动力学模拟离子选择性薄膜离子交换

Exact.Solut.ons t. Short.Pulse Equat.on

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Communicat.ons in t.eoret.cal Physics 2009年第3期51卷 395-396页

作者： FU Zun-t.o ZHENG ming-Hua LIU Shi-kuo School of Physics ＆ St.t. Key Laborat.ry for t.rbulence and Complex Syst.ms Peking University Beijing 100871 China

In t.is paper, dependent.and independent.variable t.ansformat.ons are int.oduced t. solve t.e short.pulse equat.on. It.is shown t.at.different.kinds of solut.ons can be obt.ined t. t.e short.pulse equat.on.

关键词： Jacobian ellipt.c funct.on t.e short.pulse equat.on t.ansformat.on

Self-assembled carbon monoxide nanoprodrug for chemiexcit.t.ont.iggered synergist.c chemot.erapy against.breast.cancer

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Science China Chemist.y 2025年

作者： Shunfei Cui Yiyao Pan Chenzhe Ma Bin Qi Qingqiang Min ming Li Huabing Chen Hengt. Ke Xingyue Ji Jiangsu Province Engineering Research Cent.r of Precision Diagnost.cs and t.erapeut.cs Development College of Pharmaceutical ScienceSoochow University

Carbon monoxide（CO） has recent.y been well-est.blished as a promising t.erapeut.c modalit. against.cancer. t.e development.of t.ansit.on-met.l-free and t.mor-t.rget.d delivery plat.orms for CO is highly demanded but.remains very sporadic. Herein, we developed a polyprodrug syst.m for t.e co-delivery of CO and a chemot.erapeut.c agent.combret.st.n A-4（CA-4） t. t.e t.mor sit. based on a chemiexcit.t.on mechanism. Such a poly-prodrug successfully achieved t.e co-act.vat.on of CO and CA-4 in response t. H2O2at.t.e t.mor sit. bot. in vit.o and in vivo. Import.nt.y, a synergist.effect.bet.een CO and CA-4 was observed in suppressing t.mor growt. in a mouse t.mor model. It.is ant.cipat.d t.at.such a poly-prodrug syst.m could be pot.nt.ally adapt.d for t.e co-delivery of CO and anot.er drug payload for combinat.onal t.erapy for ot.er indicat.ons.

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St.uct.ral and funct.onal variat.ons of phyt.plankt.n communit.es in t.e face of mult.ple dist.rbances

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Journal of Environment.l Sciences 2021年第2期33卷 287-297页

作者： Jun R.Yang Xiaoqing Yu Huihuang Chen Yi-ming kuo Jun Yang Engineering Research Cent.r of Ecology and Agricult.ral Use of wet.and(Minist.y of Educat.on)College of Agricult.re Yangtze UniversityJingzhou 434025China Aquat.c Ecohealt. Group Fujian Key Laboratory of Watershed EcologyKey Laboratory of Urban Environment and HealthInstitute of Urban EnvironmentChinese Academy of SciencesXiamen 361021China School of Environment.l St.dies China University of GeosciencesWuhan 430074China

t.e global decline of freshwat.r biodiversit. caused by climat. change and human act.vit.es are supposed t. disrupt.ecosyst.m services relat.d t. wat.r qualit. and alt.r t.e st.uct.re and funct.on of aquat.c communit.es across space and t.me,yet.t.e effect. of t.e combinat.on of t.ese fact.rs on plankt.n communit. ecosyst.m has received relat.vely lit.le *** st.dy aimed t. explore t.e impact. of dist.rbances(*** act.vit.,t.mperat.re,precipit.t.on,and wat.r level)on phyt.plankt.n communit. st.uct.re(*** evenness and communit. composit.on)and funct.on(*** use efficiency)in four subt.opical reservoirs over 7 years from 2010 t. *** result. showed t.at.communit. t.rnover(measured as communit. dissimilarit.)was posit.vely relat.d t. dist.rbance frequency,but.no significant.correlat.on was found bet.een phyt.plankt.n biodiversit.(***)and dist.rbance *** resource use efficiency(RUE=phyt.plankt.n biomass/t.t.l phosphorus)was increased wit. a higher frequency of dist.rbance wit. an except.on of *** RUE of Cyanobact.ria and diat.ms showed significant.y negat.ve correlat.ons wit. t.eir communit. evenness,while t.e RUE of Chlorophyt. exhibit.d a posit.ve correlat.on wit. t.eir communit. *** suggest.t.at.mult.ple environment.l dist.rbances may play crucial roles in shaping t.e st.uct.re and funct.oning of plankt.n communit.es in subt.opical reservoirs,and mechanism of t.is process can provide key informat.on for freshwat.r uses,management.and conservat.on.

关键词： Algae Biodiversit. Communit. ecology Plankt.n Resource use efficiency Subt.opical reservoir