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Implications for fault reactivation and seismicity induced by hydraulic fracturing

Petroleum Science 2024年第2期21卷 1081-1098页

作者： Zi-Han Sun ming-Guang che Li-Hong Zhu Shu-Juan Zhang Ji-Yuan Lu Chang-Yu Jin Key Laboratory of Ministry of Education on Safe Mining of Deep Metal Mines School of Resources and Civil Engineering and Key Laboratory of Liaoning Province on Deep Engineering and Intelligent TechnologyNortheastern UniversityShenyang110819LiaoningChina Research Institute of Petroleum Exploration&Development PetroChina Company LimitedBeijing100084China The Exploration and Development Research Institute of Daqing Oilfield Limited Company Daqing163458HeilongjiangChina

Evaluating the physical mechanisms that link hydraulic fracturing(HF) operations to induced earthquakes and the anticipated form of the resulting events is significant in informing subsurface fluid injection operations. Current understanding supports the overriding role of the effective stress magnitude in triggering earthquakes, while the impact of change rate of effective stress has not been systematically addressed. In this work, a modified critical stiffness was brought up to investigate the likelihood, impact,and mitigation of induced seismicity during and after hydraulic fracturing by developing a poroelastic model based on rate-and-state fraction law and linear stability analysis. In the new criterion, the change rate of effective stress was considered a key variable to explore the evolution of this criterion and hence the likelihood of instability slip of fault. A coupled fluid flow-deformation model was used to represent the entire hydraulic fracturing process in COMSOL Multiphysics. The possibility of triggering an earthquake throughout the entire hydraulic fracturing process, from fracturing to cessation, was investigated considering different fault locations, orientations, and positions along the fault. The competition between the effects of the magnitude and change rate of effective stress was notable at each fracturing stage. The effective stress magnitude is a significant controlling factor during fracturing events, with the change rate dominating when fracturing is suddenly started or stopped. Instability dominates when the magnitude of the effective stress increases(constant injection at each fracturing stage) and the change rate of effective stress decreases(the injection process is suddenly stopped). Fracturing with a high injection rate, a fault adjacent to the hydraulic fracturing location and the position of the junction between the reservoir and fault are important to reduce the Coulomb failure stress(CFS) and enhance the critical stiffness as

关键词： Hydraulic fracturing Coulomb failure stress Rate-and-state fraction model Linear stability analysis Critical stiffness Seismically induced fault

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The Anticancer Potential of Quassinoids-A Mini-Review

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Engineering 2024年第7期38卷 27-38页

作者： Cai Lu Si-Nan Lu Di Di Wei-Wei Tao Lu Fan Jin-Ao Duan ming Zhao Chun-Tao che Jiangsu Collaborative Innovation Center of Chinese Medicinal Resource Industrialization Nanjing University of Chinese MedicineNanjing 210023China National and Local Collaborative Engineering Center of Chinese Medicinal Resource Industrialization and Formulae Innovative Medicine Nanjing University of Chinese MedicineNanjing 210023China School of Chinese Medicine&School of Integrated Chinese and Western Medicine Nanjing University of Chinese MedicineNanjing 210023China School of Medicine&Holistic Integrative Medicine Nanjing University of Chinese MedicineNanjing 210023China Department of Pharmaceutical Sciences College of PharmacyUniversity of Illinois ChicagoChicagoIL 60612USA

The anticancer potential of quassinoids has attracted a great deal of attention for decades,and scientific data revealing their possible applications in cancer management are continuously increasing in the *** from the potent cytotoxic and antitumor properties of these degraded triterpenes,several quassinoids have exhibited synergistic effects with anticancer *** article provides an overview of the potential anticancer properties of quassinoids,including their cytotoxic and antitumor activities,mechanisms of action,safety evaluation,and potential benefits in combination with anticancer drugs.

关键词： Quassinoid Anticancer potential Antiproliferative mechanism Safety evaluation Synergistical combination with anticancer drugs

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Genome-wide association study of grain micronutrient concentrations in bread wheat

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Journal of Integrative Agriculture 2024年第5期23卷 1468-1480页

作者： Yongchao Hao Fanmei Kong Lili Wang Yu Zhao Mengyao Li Naixiu che Shuang Li Min Wang ming Hao Xiaocun Zhang Yan Zhao State Key Laboratory of Crop Biology/College of Agronomy Shandong Agricultural UniversityTai'an 271018China College of Resources and Environment Shandong Agricultural UniversityTai'an 271018China Jining Liangshan Ecological Environment Affairs Center Jining 272100China College of Forestry Shandong Agricultural UniversityTai'an 271018China

Bread wheat(Triticum aestivum)is a staple food crop *** genetic dissection of important nutrient traits is essential for the biofortification of wheat to meet the nutritional needs of the world's growing ***,45,298 single-nucleotide polymorphisms(SNPs)from 55K chip arrays were used to genotype a panel of 768 wheat cultivars,and a total of 154 quantitative trait loci(QTLs)were detected for eight traits under three environments by genome-wide association study(GWAS).Three QTLs(qMn-3B.1,qFe-3B.4,and qSe-3B.1/qFe-3B.6)detected repeatedly under different environments or traits were subjected to subsequent analyses based on linkage disequilibrium decay and the P-values of significant *** SNPs in the three QTL regions formed six haplotypes for qMn-3B.1,three haplotypes for qFe-3B.4,and three haplotypes for qSe-3B.1/*** analysis revealed significant differences among *** results indicated that the concentrations of several nutrient elements have been modified during the domestication of landraces to modern *** on the QTL regions,we identified 15 high-confidence genes,eight of which were stably expressed in different tissues and/or developmental ***3B02G046100 in qMn-3B.1 and TraesCS3B02G199500 in qSe-3B.1/qFe-3B.6 were both inferred to interact with metal ions according to the Gene Ontology(GO)***3B02G199000,which belongs to qSe-3B.1/qFe-3B.6,was determined to be a member of the WRKY gene ***,this study provides several reliable QTLs that may significantly affect the concentrations of nutrient elements in wheat grain,and this information will facilitate the breeding of wheat cultivars with improved grain properties.

关键词： bread wheat nutritional element GWAS domestication haplotype

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Cell replacement with stem cell-derived retinal ganglion cells from different protocols

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Neural Regeneration Research 2024年第4期19卷 807-810页

作者： Ziming Luo Kun-che Chang Spencer Center for Vision Research Byers Eye InstituteStanford University School of Medicine Department of Ophthalmology Louis J.Fox Center for Vision RestorationUniversity of Pittsburgh School of Medicine Department of Neurobiology Center of NeuroscienceUniversity of Pittsburgh School of Medicine

Glaucoma,characterized by a degenerative loss of retinal ganglion cells,is the second leading cause of blindness *** is currently no cure for vision loss in glaucoma because retinal ganglion cells do not regenerate and are not replaced after *** stem cell-derived retinal ganglion cell transplant is a potential therapeutic strategy for retinal ganglion cell degenerative *** this review,we first discuss a 2D protocol for retinal ganglion cell differentiation from human stem cell culture,including a rapid protocol that can generate retinal ganglion cells in less than two weeks and focus on their transplantation ***,we discuss using 3D retinal organoids for retinal ganglion cell transplantation,comparing cell suspensions and *** review provides insight into current knowledge on human stem cell-derived retinal ganglion cell differentiation and transplantation,with an impact on the field of regenerative medicine and especially retinal ganglion cell degenerative diseases such as glaucoma and other optic neuropathies.

关键词： cell clumps cell suspension cell transplantation differentiation direct-induced protocol glaucoma optic neuropathy regenerative medicine retinal ganglion cell retinal organoids stem cells

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Applying Prim’s Algorithm to Identify Isolated Areas for Natural Disaster Prevention and Protection

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Engineering（科研） 2018年第7期10卷 417-431页

作者： Wen-Ching Wang ming-che hsieh Chun-Hsiang Huang Department of Information Science and Management Systems National Taitung University Taiwan

Based on the principle of “pre-disaster prevention outweighs rescue during disasters”, this study targets areas threatened by natural disasters, and develops an automatic algorithm based on the Prim algorithm to serve as an automatic identification system. In the face of natural disasters that disable key facilities in the region and prevent settlements from contacting the outside world or outsiders from sending rescuers to the settlements, the proposed system helps to identify whether these regions will become isolated areas and conduct disaster mitigation and relief resource allocation before any natural disaster in order to reduce potential disaster losses. An automatic identification system, based on the threshold of channel blocking due to broken roads and bridges, determines through the decision tree model and relevant patterns whether such regions will become isolated areas by identifying areas based on the results of model analysis. The proposed system’s identification results are verified by actual case histories and comparisons;the results can be used to correctly identify isolated areas. Finally, Microsoft Visual Studio C # and Google Map are employed to apply the results and to produce an information mode for the determination and decision support of isolated areas affected by natural disasters.

关键词： Prim Algorithm Comb Route Isolation Area Hazard Decision Support System

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Numerical investigation of transient gas–solid heat transfer in a packed bed:Impact of intra-particle thermal diffusion

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Particuology 2024年第7期90卷 404-411页

作者： Hanqiao che Yuanhe Yue Zhaohua Jiang Duan Li School of Mechanical Engineering Guangxi UniversityNanningGuangxi530004China School of chemical Engineering University of BirminghamBirminghamB152TTUK Hebei Engineering Research Center of Advanced Energy Storage Technology and Equipment School of Energy and Environmental EngineeringHebei University of TechnologyTianjin300401China Hebei Key Laboratory of Thermal Science and Energy Clean Utilization School of Energy and Environmental EngineeringHebei University of TechnologyTianjin300401China School of Mechatronics and Vehicle Engineering Chongqing Jiaotong UniversityChongqing400074China School of Instrumentation and Opto-Electronic Engineering Beihang UniversityBeijing 100191China

The transient heat transfer behaviours in a packed bed have been studied using coupled computational fluid dynamics(CFD)and discrete element method(DEM).Intra-particle thermal diffusion,which is a crucial but rarely explored issue,is considered by introducing a one-dimensional diffusion equation in the DEM *** achieve a sufficiently long physical time of simulations,we further reduce the computational cost by applying periodic boundary condition to a small segment of the packed *** study demonstrates a shifting peak heat flow rate from the bottom to the top of the packed bed during the initial warming *** affirm that the influence of thermal diffusion within a particle is noteworthy only for particles exhibiting a high Biot number(e.g.,Bi=1.2).This insight enriches our understanding of heat transfer mechanisms in packed beds and their practical engineering applications.

关键词： Packed bed Intra-particle heat transfer CFD–DEM

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Electric Vehicle Charging Load Optimization Strategy Based on Dynamic Time-of-Use Tariff

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Energy Engineering 2024年第3期121卷 603-618页

作者： Shuwei Zhong Yanbo che Shangyuan Zhang Key Laboratory of Smart Grid of Education Ministry Tianjin UniversityTianjin300072China

Electric vehicle(EV)is an ideal solution to resolve the carbon emission issue and the fossil fuels scarcity problem in the ***,a large number of EVs will be concentrated on charging during the valley hours leading to new load peaks under the guidance of static time-of-use ***,this paper proposes a dynamic time-of-use tariff mechanism,which redefines the peak and valley time periods according to the predicted loads using the fuzzy C-mean(FCM)clustering algorithm,and then dynamically adjusts the peak and valley tariffs according to the actual load of each time *** on the proposed tariff mechanism,an EV charging optimization model with the lowest cost to the users and the lowest variance of the grid-side load as the objective function is ***,a weight selection principle with an equal loss rate of the two objectives is proposed to transform the multi-objective optimization problem into a single-objective optimization ***,the EV charging load optimization model under three tariff strategies is set up and solved with the mathematical solver *** results show that the EV charging load optimization strategy based on the dynamic time-of-use tariff can better balance the benefits between charging stations and users under different numbers and proportions of EVs connected to the grid,and can effectively reduce the grid load variance and improve the grid load curve.

关键词： Dynamic time-of-use tariff peak and valley time electric vehicle multi-objective optimization

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Excellent energy storage performance in Bi_(0.5)Na_(0.5)TiO_(3)-based lead-free high-entropy relaxor ferroelectrics via B-site modification

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Journal of Advanced Ceramics 2024年第3期13卷 345-353页

作者： Kaihua Yang Gengguang Luo Li Ma Ruoxuan che Zhiyi che Qin Feng Zhenyong Cen Xiyong chen Jiajun Zhou Nengneng Luo State Key Laboratory of Featured Metal Materials and Life-cycle Safety for Composite Structures School of ResourcesEnvironment and MaterialsGuangxi UniversityNanning 530004China School of Optical and Electronic Information Key Lab of Functional Materials for Electronic Information(B)of Ministry of EducationHuazhong University of Science and TechnologyWuhan 430074China

Next-generation advanced high/pulsed power capacitors urgently require dielectric materials with outstanding energy storage ***_(0.5)Na_(0.5)TiO_(3)-based lead-free materials exhibit high polarization,but the high remanent polarization and large polarization hysteresis limit their applications in dielectric ***,high-entropy perovskite relaxor ferroelectrics(Na_(0.2)Bi_(0.2)Ba_(0.2)Sr_(0.2)Ca_(0.2))(Ti1-x%Zrx%)O_(3)are designed by adding multiple ions in the A-site and replacing the B-site Ti^(4+)with a certain amount of Zr^(4+).The newly designed system showed high relaxor feature and slim polarization-electric(P-E)***,improved relaxor feature and obviously delayed polarization saturation were found with the increasing of Zr^(4+).Of particular importance is that both high recoverable energy storage density of 6.6 J/cm^(3) and energy efficiency of 93.5%were achieved under 550 kV/cm for the ceramics of x=6,accompanying with excellent frequency stability,appreciable thermal stability,and prosperous discharge *** work not only provides potential dielectric materials for energy storage applications,but also offers an effective strategy to obtain dielectric ceramics with ultrahigh comprehensive energy storage performance to meet the demanding requirements of advanced energy storage applications.

关键词： energy storage density (Bi_(0.5)Na_(0.5))TiO_(3) high-entropy perovskite ceramics polarization saturation relaxor ferroelectrics(RFEs)

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Multi-timescale optimization scheduling of interconnected data centers based on model predictive control

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Frontiers in Energy 2024年第1期18卷 28-41页

作者： Xiao GUO Yanbo che Zhihao ZHENG Jiulong SUN Energy Power Electrical Automation and Information EngineeringTianjin UniversityTianjin 300072China

With the promotion of“dual carbon”strategy,data center(DC)access to high-penetration renewable energy sources(RESs)has become a trend in the ***,the uncertainty of RES poses challenges to the safe and stable operation of DCs and power *** this paper,a multi-timescale optimal scheduling model is established for interconnected data centers(IDCs)based on model predictive control(MPC),including day-ahead optimization,intraday rolling optimization,and intraday real-time *** day-ahead optimization stage aims at the lowest operating cost,the rolling optimization stage aims at the lowest intraday economic cost,and the real-time correction aims at the lowest power fluctuation,eliminating the impact of prediction errors through coordinated multi-timescale *** simulation results show that the economic loss is reduced by 19.6%,and the power fluctuation is decreased by 15.23%.

关键词： model predictive control interconnected data center multi-timescale optimized scheduling distributed power supply/landscape uncertainty

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Constructing Built-In Electric Fields with Semiconductor Junctions and Schottky Junctions Based on Mo-MXene/Mo-Metal Sulfides for Electromagnetic Response

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Nano-Micro Letters 2024年第10期16卷 453-473页

作者： Xiaojun Zeng Xiao Jiang Ya Ning Yanfeng Gao Renchao che School of Materials Science and Engineering Jingdezhen Ceramic UniversityJingdezhen 333403People's Republic of China School of Materials Science and Engineering Shanghai UniversityShanghai 200444People's Republic of China Laboratory of Advanced Materials Shanghai Key Lab of Molecular Catalysis and Innovative MaterialsAcademy for Engineering and TechnologyFudan UniversityShanghai 200438People's Republic of China Zhejiang Laboratory Hangzhou 311100People's Republic of China

The exploration of novel multivariate heterostructures has emerged as a pivotal strategy for developing high-performance electromagnetic wave(EMW)absorption ***,the loss mechanism in traditional heterostructures is relatively simple,guided by empirical observations,and is not *** this work,we presented a novel semiconductor-semiconductor-metal heterostructure sys-tem,Mo-MXene/Mo-metal sulfides(metal=Sn,Fe,Mn,Co,Ni,Zn,and Cu),including semiconductor junctions and Mott-Schottky *** skillfully combining these distinct functional components(Mo-MXene,MoS_(2),metal sulfides),we can engineer a multiple heterogeneous interface with superior absorption capabilities,broad effective absorption bandwidths,and ultrathin matching *** successful establishment of semiconductor-semiconductor-metal heterostructures gives rise to a built-in electric field that intensifies electron transfer,as confirmed by density functional theory,which collaborates with multiple dielectric polarization mechanisms to substantially amplify EMW *** detailed a successful synthesis of a series of Mo-MXene/Mo-metal sulfides featuring both semiconductor-semiconductor and semiconductor-metal *** achievements were most pronounced in Mo-MXene/Mo-Sn sulfide,which achieved remarkable reflection loss values of-70.6 dB at a matching thickness of only 1.885 *** cross-section calculations indicate that these MXene/Mo-metal sulfides have tremendous potential in practical military stealth *** work marks a departure from conventional component design limitations and presents a novel pathway for the creation of advanced MXene-based composites with potent EMW absorption capabilities.

关键词： Semiconductor-semiconductor-metal heterostructure Semiconductor junctions Mott-Schottky junctions Built-in electric field Electromagnetic wave absorption

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