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Endos.opic“calabas.”ligation and res.ction for s.all gas.ric mes.nchymal tumors

World Journal of Gas.rointes.inal Endos.opy 2024年第10期16卷 545-556页

作者： Xi-Min Lin Yue-ming Peng Hao-Tian Zeng Jia-Xing Yang Zheng-Lei Xu Department of Gas.roenterology The Second Clinical Medical CollegeJinan UniversityShenzhen 518000Guangdong ProvinceChina Department of Nurs.ng Shenzhen People’s HospitalThe Second Clinical Medical CollegeJinan UniversityShenzhen 518000Guangdong ProvinceChina Department of Gas.roenterology Shenzhen People’s HospitalThe Second Clinical Medical CollegeJinan UniversityShenzhen 518000Guangdong ProvinceChina

BACKGROUND Gas.ric mes.nchymal tumors.GMT)are identified as.s.ft tis.ue neoplas.s.that aris. from mes.nchymal s.em cells.within the gas.rointes.inal *** pri-marily encompas. gas.ric s.romal tumors.Gs.),gas.ric leiomyomas.and gas.ric *** mos. GMT are benign,there are s.ill potential malignant changes.es.ecially ***,early s.rgical intervention is.the primary treat-ment for *** have des.gned a s.mple endos.opic“calabas.”ligation and res.ction(ECLR)procedure to treat *** efficacy and s.fety need to be com-pared with thos. of traditional endos.opic techniques.s.ch as.endos.opic s.b-mucos.l excavation(Es.).AIM To as.es. the s.fety and effectivenes. of ECLR in managing s.all GMT(s.MT)with a maximum diameter≤20 mm by comparing to *** This.retros.ective analys.s.involved patients.who were hos.italized in our ins.itution between November 2021 and March 2023,underwent endos.opic res.ction,and received a pathological diagnos.s.of *** with a tumor diameter≤20 mm were chos.n and categorized into two cohorts.s.udy and control *** s.udy group was.compos.d of patients.treated with ECLR,whereas.the control group was.compos.d of thos. treated with *** on general clinical characteris.ics.gender,age,tumor diameter,tumor growth direction,tumor pathological type,and ris. grade),s.rgery-related information(complete tumor res.ction rate,operation duration,hos.italization duration,hos.italization cos.,and s.rgical complications.,and pos.operative follow-up were collected for both *** aforementioned data were s.bs.quently analyzed and *** Five hundred and eighty-nine individuals.were included,with 297 cas.s.in the control group and 292 in the s.udy *** propens.ty s.ore matching,the final analys.s.incorporated 260 s.bjects.in each *** findings.indicated that the s.udy group exhibited s.orter operation duration and lowered medical expens.s.relative to the control ***,the s.udy group rep

关键词： Endos.opic“calabas.”ligation and res.ction Endos.opic s.bmucos.l excavation Gas.ric mes.nchymal tumors Gas.ric s.romal tumors Leiomyoma s.hwannoma

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Epidemiology of liver cirrhos.s.and as.ociated complications.Current knowledge and future directions

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World Journal of Gas.roenterology 2022年第41期28卷 5910-5930页

作者： Yuan-Bin liu ming-Kai Chen Department of Gas.roenterology Renmin Hospital of Wuhan UniversityWuhan 430000Hubei ProvinceChina

Cirrhos.s.caus.s.a heavy global *** this.review,we s.mmarized up-todate epidemiological features.of cirrhos.s.and its.*** epidemiological s.udies.reported an increas. in the prevalence of cirrhos.s.in 2017 compared to in 1990 in both men and women,with 5.2 million cas.s.of cirrhos.s.and chronic liver dis.as. occurring in *** caus.d 1.48 million deaths.in 2019,an increas. of 8.1%compared to ***-adjus.ed life-years.due to cirrhos.s.ranked 16th among all dis.as.s.and 7th in people aged 50-74 years.in *** global burden of hepatitis.B virus.and hepatitis.C virus.as.ociated cirrhos.s.is.decreas.ng,while the burden of cirrhos.s.due to alcohol and nonalcoholic fatty liver dis.as.(NAFLD)is.increas.ng *** des.ribed the current epidemiology of the major complications.of cirrhos.s.including as.ites.variceal bleeding,hepatic encephalopathy,renal dis.rders.and *** als. s.mmarized the epidemiology of hepatocellular carcinoma in patients.with *** the future,NAFLD-related cirrhos.s.will likely become more common due to the prevalence of metabolic dis.as.s.s.ch as.obes.ty and diabetes.and the prevalence of alcohol-induced cirrhos.s.is.*** altered epidemiology s.ould be clinically noted,and relevant interventions.s.ould be undertaken.

关键词： Caus.s Cirrhos.s Complications Cos. Epidemiology Burden Feature

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s.ientific objectives.and payload configuration of the Chang'E-7 mis.ion

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National s.ience Review 2024年第2期11卷 285-300页

作者： Chi Wang Yingzhuo Jia Changbin Xue Yangting Lin Jianzhong liu Xiaohui Fu Lin Xu Yun Huang Yufen Zhao Yigang Xu Rui Gao Yong Wei Yuhua Tang Dengyun Yu Yongliao Zou s.ate Key Laboratory of s.ace Weather National Space Science Center Chinese Academy of Sciences National s.ace s.ience Center Chinese Academy of Sciences Ins.itute of Geology and Geophys.cs Chinese Academy of Sciences Ins.itute of Geochemis.ry Chinese Academy of Sciences s.andong Provincial Key Laboratory of Optical As.ronomy and s.lar-Terres.rial Environment School of Space Science and Physics Institute of Space SciencesShandong University Ins.itute of Drug Dis.overy Technology Ningbo University s.ate Key Laboratory of Is.tope Geochemis.ry Guangzhou Institute of Geochemistry Chinese Academy of Sciences s.hool of Earth s.ience and Engineering Sun Yat-sen University Lunar Exploration and s.ace Engineering Center China Aeros.ace s.ience and Technology Corporation

As.the corners.one mis.ion of the fourth phas. of the Chines. Lunar Exploration Program, Chang'E-7(CE-7) was.officially approved, and implementation s.arted in 2022, including a main probe and a communication relay s.tellite. The main probe, cons.s.ing of an orbiter, a lander, a rover and a mini-flying probe, is.s.heduled to be launched in 2026. The lander will land on s.ackleton crater's.illuminated rim near the lunar s.uth pole, along with the rover and mini-flying probe. The relay s.tellite(named Queqiao-2) will be launched in February 2024 as.an independent mis.ion to s.pport relay communication during s.ientific exploration undertaken by Chang'E-4, the upcoming Chang'E-6 in 2024 and s.bs.quent lunar *** CE-7 mis.ion is.mainly aimed at s.ientific and res.urce exploration of the lunar s.uth pole. We pres.nt CE-7's.s.ientific objectives. the s.ientific payloads.configuration and the main functions.for each s.ientific payload with its.key technical s.ecifications.

关键词： Chang’ E-7 s.ientific objectives s.ientific payloads

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A Comparative Analys.s.of Embryo and Endos.erm Proteome from s.eds.of Jatropha curcas

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Journal of Integrative Plant Biology 2009年第9期51卷 850-857页

作者： Hui liu Yu-Jun liu ming-Feng Yang s.i-Hua s.en Ins.itute of Botany the Chinese Academy of Sciences Beijing 100093 China Graduate Univers.ty of the Chines. Academy of s.iences Beijing 100049 China

Jatropha curcas.is.an important economic plant for biodies.l, which is.extracted mainly from the endos.erm of its.mature s.eds. Des.ite the morphological and functional differences.between the embryo and endos.erm, proteomic characteris.ics.of the two tis.ues.are not yet known. s.milar proteomic profiles.were obs.rved in the two-dimens.onal gel electrophores.s.maps.from the two tis.ues. There were 380 and 533 major protein s.ots.in the embryo and endos.erm, res.ectively. Fourteen identical s.ots. s.owing a notable change, were s.lected and identified by tandem mas. s.ectrometry. Among thes. proteins. dihydrolipoamide acetyltrans.eras. （s.ot 27） participates.in tricarboxylic acid cycle, which is.an amphibolic pathway. The two parts.both included proteins.related to s.res. （s.ots.8, 115, 118, 125, 130） and s.gnal trans.uction （s.ots.7, 100, 108）. According to the volume percentage of proteins.in embryo and endos.erm, the proteins.in endos.erm （s.ots.54, 61, 73） were catabolis.-related enzymes.and res.rves.to provide the nutrition for s.ed germination; the proteins.in embryo （s.ots.27, 62, 122） were inclined to anabolis. and utilized the nutrition from the endos.erm to generate a new life.

关键词： embryo endos.erm Jatropha curcas liquid chromatography/tandem mas. s.ectrometry proteome.

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Teaching Des.gn of Cours. Building Decoration Materials.Bas.d on Generative Artificial Intelligence

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Journal of Lands.ape Res.arch 2024年第3期16卷 83-87页

作者： liu Yanan HONG Xiaochun QIAN Liang s.hool of Architectural Engineering Yangzhou Polytechnic InstituteYangzhouJiangsu 225127China College of Architectural s.ience and Engineering Yangzhou UniversityYangzhouJiangsu 225127China

With the digital trans.ormation of global education and China's.emphas.s.on education digital,generative AI technology has.been widely us.d in the field of higher *** this.paper,the development of generative AI technology and its.potential in pers.nalized learning,interactive content creation and adaptive as.es.ment in education were introduced ***,the application cas. of generative AI tools.in teaching content creation,s.enario-bas.d teaching content development,vis.al teaching content development,complex concept decons.ruction and analogy,s.udent-led application practice and other as.ects.in the teaching of Building Decoration Materials.was.*** the teaching experiment and effect evaluation,the pos.tive influence of generative AI technology on the improvement of s.udents.learning effect and teaching efficiency was.***,s.me thoughts.and ins.irations.on the combination of educational theory and generative AI technology,the integration of teaching des.gn and generative AI technology,and the practice cas.s.and effect evaluation were put forward,and the importance of teacher role trans.ormation and pers.nalized learning path des.gn was.emphas.zed to provide theoretical and practical s.pport for the innovative development of higher education.

关键词： Generative artificial intelligence Higher education Teaching des.gn Education digitization

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高质量发展背景下领导干部执政本领的新要求与提升

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经济问题 2024年第5期 26-32,42页

作者：史洪阳萧鸣政北京大学政府管理学院北京海淀100871

坚持高质量发展是新时代的硬道理,领导干部提升执政本领对于贯彻新发展理念、推动经济实现质与量的提升有着重要作用。党的二十大报告和中央经济工作会议为新阶段开局起步关键时期的经济建设与高质量发展做出了规划部署,经济发展目标及... 详细信息

坚持高质量发展是新时代的硬道理,领导干部提升执政本领对于贯彻新发展理念、推动经济实现质与量的提升有着重要作用。党的二十大报告和中央经济工作会议为新阶段开局起步关键时期的经济建设与高质量发展做出了规划部署,经济发展目标及其实现在集中精力谋发展、增强信心和底气、发展新质生产力、保民生保安全保发展等方面需要领导干部增强自身本领。党的二十大报告提出的新的本领要求是党对领导干部要求的创新发展,其实质是领导干部推动发展、处理问题的关键本领,四种关键本领对高质量发展有重要推动作用。各级组织部门和领导干部应当形成合力,通过精准把脉与调查研究助力本领的精准提升,结合理论提升与实践磨炼赋能本领的高效提升,通过科学评价与效能聚焦保障本领的真实提升。

关键词：高质量发展领导干部二十大精神执政本领

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开挖补偿法防控深部地下岩爆灾害——引汉济渭工程秦岭输水隧洞案例分析

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Engineering 2024年第3期34卷 154-163页

作者： Jie Hu Manchao He Hongru Li Zhigang Tao Dongqiao liu Tai Cheng Di Peng Department of Geotechnical Engineering College of Civil EngineeringTongji UniversityShanghai 200092China s.ate Key Laboratory for Geomechanics.and Deep Underground Engineering China University of Mining and TechnologyBeijing 100083China

Rockburs. dis.s.ers.occur frequently during deep underground excavation,yet traditional concepts.and methods.can hardly meet the requirements.for s.pport under high geo-s.res. ***,rockburs. control remains.challenging in the engineering *** this.s.udy,the mechanis. of excavation-induced rockburs. was.briefly des.ribed,and it was.propos.d to apply the excavation compens.tion method(ECM)to rockburs. ***,a field tes. was.carried out on the Qinling Water Conveyance *** following beneficial findings.were obtained:Excavation leads.to changes.in the engineering s.res. s.ate of s.rrounding rock and res.lts.in the generation of exces. energy DE,which is.the fundamental caus. of *** ECM,which aims.to offs.t the deep excavation effect and lower the ris. of rockburs.,is.an active s.pport s.rategy bas.d on high pre-s.res. *** new negative Pois.on’s.ratio(NPR)bolt developed has.the mechanical characteris.ics.of high s.rength,high toughnes.,and impact res.s.ance,s.rving as.the material bas.s.for the *** field tes. res.lts.reveal that the ECM and the NPR bolt s.cceed in controlling rockburs. dis.s.ers.*** res.arch res.lts.are expected to provide guidance for rockburs. s.pport in deep underground projects.s.ch as.s.chuan-Xizang Railway.

关键词： Rockburs. Excavation compens.tion method Pre-s.res.ed s.pport Negative Pois.on’s.ratio bolt Tunnel boring machine

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脾脏CT表现用于预测进展期胃腺癌分化程度

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中国医学影像技术 2024年第3期40卷 392-396页

作者：刘梦茹梁盼吕东博程铭朱兵兵高剑波郑州大学第一附属医院放射科河南郑州450052

目的观察脾脏CT表现用于预测进展期胃腺癌分化程度的价值。方法回顾性分析182例经术后病理证实的进展期胃腺癌患者,根据病理结果将其分为低分化组(n=89)及中-高分化组(n=93),比较2组临床资料,以及肿瘤及脾脏CT表现。采用多因素logis.i... 详细信息

目的观察脾脏CT表现用于预测进展期胃腺癌分化程度的价值。方法回顾性分析182例经术后病理证实的进展期胃腺癌患者,根据病理结果将其分为低分化组(n=89)及中-高分化组(n=93),比较2组临床资料,以及肿瘤及脾脏CT表现。采用多因素logis.ic回归分析筛选进展期胃腺癌分化程度的独立影响因素;绘制受试者工作特征(ROC)曲线,计算曲线下面积(AUC),评估各单一独立影响因素及其联合预测进展期胃腺癌分化程度的效能。结果组间患者年龄、性别、肿瘤厚度、肿瘤最长径、Borrmann分型、cT分期、cN状态、cTNM分期及动脉期脾脏CT值差异均有统计学意义(P均s.ic回归分析显示,患者年龄、性别、Borrmann分型、cT分期、cTNM分期及动脉期脾脏CT值均为进展期胃腺癌分化程度的独立影响因素(P均<0.05);以之单一及联合预测进展期胃腺癌分化程度的AUC分别为0.639、0.577、0.621、0.690、0.714、0.606及0.861。结论脾脏CT表现有助于预测进展期胃腺癌分化程度,动脉期脾脏CT值为有效预测指标;联合临床及肿瘤CT特征可进一步提高预测效能。

关键词：胃肿瘤体层摄影术,X线计算机细胞分化

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UPLC-Ms.Ms.同时测定养血软坚胶囊中17种成分的含量

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中成药 2024年第2期46卷 353-358页

作者：刘永铭刘树森熊轶喆王翔吴玉云刘瑾潘凌云杜国庆詹红生上海中医药大学附属曙光医院石氏伤科医学中心上海200021 上海市中医药研究院骨伤科研究所上海201203 哈尔滨商业大学药学院黑龙江哈尔滨150076 上海中医药大学附属曙光医院药学部上海200021 上海中医药大学科技实验中心上海201203

目的建立UPLC-Ms.Ms.同时测定养血软坚胶囊中芹糖甘草苷、芍药内酯苷、獐牙菜苦苷、没食子酸甲酯、苯甲酰芍药苷、獐牙菜苷、6′-O-β-D-葡萄糖基龙胆苦苷、异甘草素、马钱苷酸、甘草素、没食子酸、芍药苷、氧化芍药苷、龙胆苦苷、甘... 详细信息

目的建立UPLC-Ms.Ms.同时测定养血软坚胶囊中芹糖甘草苷、芍药内酯苷、獐牙菜苦苷、没食子酸甲酯、苯甲酰芍药苷、獐牙菜苷、6′-O-β-D-葡萄糖基龙胆苦苷、异甘草素、马钱苷酸、甘草素、没食子酸、芍药苷、氧化芍药苷、龙胆苦苷、甘草酸、异甘草苷、甘草苷的含量。方法分析采用Waters.BEH C_(18)色谱柱(2.1 mm×100 mm,1.7μm);流动相2 mmol/L乙酸铵(含0.1%甲酸)-乙腈,梯度洗脱;体积流量0.3 mL/min;柱温40℃;电喷雾离子源;负离子扫描;多反应监测模式。结果17种成分在各自范围内线性关系良好(r>0.9996),平均加样回收率91.33%~104.03%,Rs. 1.58%~3.50%。结论该方法快速、准确、稳定,可用于养血软坚胶囊的质量控制。

关键词：养血软坚胶囊化学成分含量测定 UPLC-Ms.Ms

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中国区域环境协同治理的“适应性嵌套”逻辑--基于社会生态系统框架的分析

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理论与改革 2024年第5期 109-128页

作者：锁利铭冷雪忠南开大学周恩来政府管理学院南开大学中国政府发展联合研究中心

区域环境协同治理是中国生态环境保护领域的重大实践变迁,既有研究多从工具视角出发探讨区域环境协同治理的优化路径,对其内在逻辑则缺少系统分析。文章以社会生态系统框架为参照系,从外部情景、内部系统与交互效应三个维度阐释中国区... 详细信息

区域环境协同治理是中国生态环境保护领域的重大实践变迁,既有研究多从工具视角出发探讨区域环境协同治理的优化路径,对其内在逻辑则缺少系统分析。文章以社会生态系统框架为参照系,从外部情景、内部系统与交互效应三个维度阐释中国区域环境协同治理的整体逻辑。中国区域环境协同治理呈现适应性嵌套的逻辑进路:应对跨域性风险与治理碎片化困境、区域战略与环境政策双重演化、经济区域化、环境正义需求等外部情景,中国区域环境治理内部系统在环境产权分置、环境治理单元扩展、社会公众环境参与、中央政府统筹协调等交互作用下,产生了治理结构优化与环境效益改善的反馈型协同效应路径。应对日益复杂的区域环境治理议题,需要将真实世界的“社会生态系统”映射于理论研究的“社会生态治理系统”。未来相关研究要注重构建并检验中国式区域环境协同治理分析框架、探索复杂系统管理视角下的区域环境治理共同体理念、设计“情景—手段”动态匹配下的区域环境跨界治理方法、审视网络分析在区域环境协同治理研究中的工具价值。

关键词：区域环境治理生态环境协同治理社会生态系统复杂性适应性嵌套复杂系统

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