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Large Time Behavior of Entropy Solutions to Some Hyperbolic System with Dissipative Structure

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Acta Mathematicae Applicatae Sinica 2013年第3期29卷 509-516页

作者： Hui-min yu Department of Mathematics Shandong Normal University

In this paper the large time behavior of the global L∞ entropy solutions to the hyperbolic system with dissipative structure is investigated. It is proved that as t → ∞ the entropy solutions tend to a constant equilibrium state in L2 norm with exponential decay even when the initial values are arbitrarily large. As an illustration, a class of 2 × 2 system is studied.

关键词： large time behavior fully dissipative system entropy solutions

Natural killer cells in hepatocellular carcinoma： current status and perspectives for future immunotherapeutic approaches

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Frontiers of Medicine 2017年第4期11卷 509-521页

作者： min yu Zonghai Li State Key Laboratory of Oncogenes and Related Genes Shanghai Cancer Institute Renji Hospital Shanghai Jiao Tong University School ofMedicine Shanghai 200032 China

Hepatocellular carcinoma （HCC） is currently the fifth most common malignancy and the third leading cause of cancer-related mortalities worldwide. In the last few years, treatments for HCC have significantly improved from a mere surgical resection to a series of minimally invasive therapies and targeted drugs. However, recurrence frequently occurs even upon curative therapeutics, and drug therapies generally produce disappointing results, with the overall prognosis dismal. This challenging clinical scenario warrants new effective and life-prolonging strategies for patients with HCC. Compelling evidence suggests that NK cells play a critical role in the immune function of the fiver and in the immune defenses against HCC, indicating that HCC might be an ideal target for NK cell-based immunotherapies. To obtain comprehensive insights into the putative influence of NK cells on HCC, this paper summarizes current knowledge on NK cells in HCC and discusses the usefulness and prospects of NK cell-based immunotherapies. Critical issues that require consideration for the successful clinical translation of NK cell-based therapies are also addressed. If appropriately used and further optimized, NK cell- based therapies could dominate important roles in the future immunotherapeutic market of HCC.

关键词： natural killer cell hepatocellular carcinoma immunotherapy

Phosphoinositides:Emerging players in plant salinity stress tolerance

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Molecular Plant 2021年第12期14卷 1973-1975页

作者： Sergey Shabala min yu International Research Centre for Environmental Membrane Biology Foshan UniversityFoshan 528041China Tasmanian Institute of Agriculture University of TasmaniaHobartTas 7001Australia

Soil salinity reduces the biodiversity of natural ecosystems and severely limits sustainability and profitability of agricultural pro-duction *** the increasing reliance of modern agricul-ture on irrigation(Liu et al.,2020a),the extent of the soil salinity is only going to increase under current climate trends *** this context,achieving global food security in the 21 st century will be not feasible without developing a salt-tolerant crop ***,the physiological and genetic complexity of this trait has significantly handicapped progress in the field.

关键词： soil salinity germplasm

Nonlinear interaction mechanisms of disturbances in supersonic flat-plate boundary layers

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Science China(Physics,Mechanics & Astronomy) 2014年第11期57卷 2141-2151页

作者： yu min LUO JiSheng Department of Mechanics Tianjin University

Due to the complexity of compressible flows,nonlinear hydrodynamic stability theories in supersonic boundary layers are not *** order to reveal the nonlinear interaction mechanisms of the rapidly amplified 3-D disturbances in supersonic boundary layers at high Mach numbers,the nonlinear evolutions of different disturbances in flat-plate boundary layers at Mach number 4.5,6 and 8 are analyzed by numerical *** can be concluded that the 3-D disturbances are amplified rapidly when the amplitude of the 2-D disturbance reaches a certain *** most rapidly amplified 3-D disturbances are Klebanoff type(K-type)disturbances which have the same frequency as the 2-D *** these K-type 3-D disturbances,the disturbances located at the junction of upper branch and lower branch of the neutral curve are amplified *** analyzing the relationship between the amplification rate and the spanwise wavenumber of the 3-D disturbances at different evolution stages,the mechanism of the spanwise wavenumber selectivity of K-type 3-D disturbances in the presence of a finite amplitude 2-D disturbance is explained.

关键词： disturbance supersonic junction branch introducing selectivity compressible hydrodynamic explained infinity

OPTIMIZING DESIGN OF MECHANICAL SELF-CENTERING DEVICE FOR SUSPENSION HEIGHT

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Chinese Journal of Mechanical Engineering 2008年第6期21卷 69-75页

作者： CAO min ZHANG Yongchao yu Fan School of Mechanical Engineering Shanghai Jiaotong University Shanghai 200240 China

Firstly, in view of the respective defects of existing self-centering devices for vehicle suspension height, the design scheme of the proposed mechanical self-centering device for suspension height is described. Taking the rear suspension of a certain light bus as a research example, the structures and parameters of the novel device are designed and ascertained. Then, the road excitation models, the performance evaluation indexes and the half-vehicle model are built, the simulation outputs of time and frequency domain are obtained with the road excitations of random and pulse by using MATLAB/Simulink software. So the main characteristics of the self-centering suspension are presented preliminarily. Finally, a multi-objective parameter design optimization model for the self-centering device is built by weighted sum approach, and optimal solution is obtained by adopting complex approach. The relevant choosing-type parameters for self-centering device components are deduced by using discrete variable optimal method, and the optimal results are verified and analyzed. So the performance potentials of the self-centering device are exerted fully in condition of ensuring overall suspension performances.

关键词： Suspension height Self-centering Vehicle height adjustment Optimizing design Multi-objective optimization

THE STRUCTURAL FLOW IN PIPE CONTAINING POROUS MEDIUM SATURATED WITH POWER-LAW FLUID

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Journal of Hydrodynamics 2012年第1期24卷 138-144页

作者： ZHOU Xiao-jun yu min-chao School of Mechatronics-Engineering and Automation Shanghai UniversityShanghai 200072China

In this article,the method of volume averaging of flow in porous media and averaging theorem was employed to the Navier-Stokes *** total drag force per unit volume was considered as the bulk damping resistance due to the porous structure（i.e.,the Darcy resistance）and the resistance due to the inertia force（i.e.,the Forchheimer resistance）,then the Brinkman-Forchheimer extended Darcy model was obtained from average momentum *** structural flow in a pipe containing porous medium saturated with power law fluid was applied in the present study.A new theoretical analysis of fully developed non-Darcy flow in a pipe containing a fibrous medium saturated with power law fluid was *** the integration method,the boundary layer solutions were obtained for flow core velocity and its *** theoretical solutions were used to analyze the effects of the Darcy number and inertia parameter on the axial velocity profile in the porous medium pipe.

关键词： power-law fluid porous media volume averaging structural flow non-Darcy regime

桂枝芍药知母汤治疗膝骨性关节炎关节镜清理术后肿痛临床观察

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中国中医药现代远程教育 2025年第2期23卷 68-70页

作者：喻敏钟喜艳南昌市洪都中医院手术二科江西南昌330000

目的探究桂枝芍药知母汤治疗膝骨性关节炎关节镜清理术后肿痛的临床效果。方法选取南昌市洪都中医院收治的膝骨性关节炎关节镜清理术后肿痛患者69例作为研究对象,按随机数字表法分为对照组(34例)和观察组(35例)。对照组予常规治疗,观察... 详细信息

目的探究桂枝芍药知母汤治疗膝骨性关节炎关节镜清理术后肿痛的临床效果。方法选取南昌市洪都中医院收治的膝骨性关节炎关节镜清理术后肿痛患者69例作为研究对象,按随机数字表法分为对照组(34例)和观察组(35例)。对照组予常规治疗,观察组在对照组基础上予桂枝芍药知母汤治疗,比较两组术前及术后1 d、3 d、7 d、14 d视觉模拟量表(VAS)评分、膝关节肿胀值并评估临床疗效。结果术前,两组VAS评分、膝关节肿胀值比较,差异无统计学意义(P>0.05);术后1 d、3 d、7 d、14 d,观察组VAS评分、膝关节肿胀值均低于对照组(P<0.05)。观察组临床治疗总有效率为97.14%(34/35),高于对照组的82.35%(28/34),差异有统计学意义(P<0.05)。结论对膝骨性关节炎关节镜清理术后肿痛患者实施桂枝芍药知母汤治疗,可有效缓解疼痛、消除肿胀,提高临床效果。

关键词：膝骨性关节炎关节镜清理术术后肿痛桂枝芍药知母汤中医药疗法

Immunocytochemical Identification and Localization of Diffuse Neuroendocrine System (DNES) Cells in Gastrointestinal Tract of Channel Catfish (Ictalurus punctatus)

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Agricultural Sciences in China 2009年第2期8卷 238-243页

作者： HE min WANG Kai-yu ZHANG yu College of Veterinary Medicine Sichuan Agricultural University Ya＇an 625014 P.R.China

To detect distribution and relative frequency of diffuse neuroendocrine system （DNES） cells in the gastrointestinal tract of channel catfish （lctalurus punctatus）, the intestinal tract of channel catfish was divided into seven portions from proximal to distal： the enlarged area after oesophagus, cardia, fundus, pylorus, and anterior, middle, and posterior intestine. Immunohistochemical method using the strept avidin-biotin-complex （SABC） was employed. All antisera between seven portions of the channel catfish were compared statistically using statistical package for the social science （SPSS）. Five types of DNES ceils were determined： neuropeptide Y-immunoreactive （NPY-IR） cells were demonstrated in both anterior and middle intestine; serotonin （5-HT） immunoreactive cells were detected throughout the whole gastrointestinal tract; vasoactive intestinal peptide （VIP） positive cells were at the highest frequency in pylorus; glucagon-immunoreactive （GLU-IR） cells were moderate in number in the fundus and anterior, middle intestine, and no immunoreactivity was determined in the other portions; somatostatin （SOM） positive cells were more abundant in the anterior and middle intestine. The regional distribution and relative frequency of immunoreactive cells in the channel catfish, Ictalurus punctatus, are essentially similar to those of other fish. However, some characteristics are observed in this species, which further proved that the diversity of the physiological function of DNES cells was based on their morphology.

关键词： channel catfish lctalurus punctatus gastrointestinal tract DNES cells immunocytochemistry

Using the Haddon matrix to explore medical response strategies for terrorist subway bombings

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Military Medical Research 2019年第4期6卷 320-327页

作者： Tie-Cheng Yan min yu Institute of Health Service and Transfusion Medicine Academy of Military Medical SciencesNo.27 Taiping RoadBeijing 100850China

Background:Since the 1970 s,terrorist bombings in subways have been frequently occurring *** cope with this threat and to provide medical response countermeasures,we analyzed the characteristics of subway bombing terrorist attacks and used the Haddon matrix to explore medical response ***:First,we analyzed 111 subway bombings from 1970 to 2017 recorded in the Global Terrorism Database to provide a reference for the strategy ***,we convened an expert panel to use the Haddon matrix to explore the medical response strategies to subway ***:In recent decades,at least one bombing attack occurs every 3 *** by the Haddon matrix,the influencing factors of medical responses to conventional subway bombings include the adequacy of first-aid kits and the medical evacuation equipment,the traffic conditions affecting the evacuation,the continuity and stability of communication,as well as the factors exclusively attributed to dirty bomb attacks in subways,such as ionizing radiation protection capabilities,the structure of the radiation sickness treatment network based on the subway lines,and the disposal of radioactive *** factors form the basis of the strategy ***:Since subway bombings are long-term threats,it is necessary to have proper medical response *** on the Haddon matrix,we explored the medical response strategies for terrorist subway bombings,especially dirty bomb *** matrix can help policymakers systematically find the most important factors,which makes the preparations of the response more efficient.

关键词： Haddon matrix Subway Terrorism Bomb attack Medical response