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Journal of Forestry Research 2017年第1期28卷 173-181页

作者： cheol min lee Tae-Sung Kwon Kwangil Cheon Center for Forest and Climate Change Korea Forest Research InstituteSeoulRepublic of Korea Division of Forest Insect Pests and Diseases Korea Forest Research InstituteSeoulRepublic of Korea National Institute of Ecology Eco-Database ManagementSeochenRepublic of Korea

In Korea, damaging typhoons related to climate change have increased steadily since the 1990s. Red pine （Pinus densiflora） forests in Gwangneung Forest were greatly disturbed by typhoon Kompasu in 2010. A survey was carried out to clarify differences in ground beetle （Coleoptera： Carabidae） communities between forest gaps and undamaged forests. Ground beetles were sampled using pitfall traps from early May to late October 2011. Vegetation changes, litter layer, organic matter layer, and soil conditions were also measured. A total of 1035 ground beetles of 32 species were collected. Contrary to our expectation, species richness, abundance, and community structure of the ground beetles in forest gaps were similar to those in undamaged forests. Species richness and abundance of habitat type were also similar. However, species diversity and estimated species richness in forest gaps were significantly higher than in undamaged forests. These findings suggest that forest gaps formed by a typhoon did not lead to great change in ground beetle communities.

关键词： Climate change Ground beetle Forest gap Red pine forest Typhoon

Early expressions of hypoxia-inducible factor 1alpha and vascular endothelial growth factor increase the neuronal plasticity of activated endogenous neural stem cells after focal cerebral ischemia

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Neural Regeneration Research 2014年第9期9卷 912-918页

作者： Seung Song Jong-Tae Park Joo Young Na Man-Seok Park Jeong-Kil lee min-cheol lee Hyung-Seok Kim Department of Forensic Medicine Chonnam National University Medical School Department of Neurology Chonnam National University Medical School Department of Neurosurgery Chonnam National University Medical School Department of Pathology Chonnam National University Medical School

Endogenous neural stem cells become ＂activated＂ after neuronal injury, but the activation sequence and fate of endogenous neural stem cells in focal cerebral ischemia model are little known. We evaluated the relationships between neural stem cells and hypoxia-inducible factor-1α and vascular endothelial growth factor expression in a photothromobotic rat stroke model using immunohistochemistry and western blot analysis. We also evaluated the chronological changes of neural stem cells by 5-bromo-2′-deoxyuridine（BrdU） incorporation. Hypoxia-inducible factor-1α expression was initially increased from 1 hour after ischemic injury, followed by vascular endothelial growth factor expression. Hypoxia-inducible factor-1α immunoreactivity was detected in the ipsilateral cortical neurons of the infarct core and peri-infarct area. Vascular endothelial growth factor immunoreactivity was detected in bilateral cortex, but ipsilateral cortex staining intensity and numbers were greater than the contralateral cortex. Vascular endothelial growth factor immunoreactive cells were easily found along the peri-infarct area 12 hours after focal cerebral ischemia. The expression of nestin increased throughout the microvasculature in the ischemic core and the peri-infarct area in all experimental rats after 24 hours of ischemic injury. Nestin immunoreactivity increased in the subventricular zone during 12 hours to 3 days, and prominently increased in the ipsilateral cortex between 3–7 days. Nestin-labeled cells showed dual differentiation with microvessels near the infarct core and reactive astrocytes in the peri-infarct area. BrdU-labeled cells were increased gradually from day 1 in the ipsilateral subventricular zone and cortex, and numerous BrdU-labeled cells were observed in the peri-infarct area and non-lesioned cortex at 3 days. BrdU-labeled cells rather than neurons, were mainly co-labeled with nestin and GFAP. Early expressions of hypoxia-inducible factor-1α and vascular endothelial gr

关键词： nerve regeneration brain ischemia neural stem cell neural precursor cell hypoxia-inducible factor 1α vascular endothelial growth factor microenvironment photothrombosis neural regeneration

Effects of Hwangryunhaedok-tang on gastrointestinal motility function in mice

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World Journal of Gastroenterology 2017年第15期23卷 2705-2715页

作者： Hyoyeon Kim Iksung Kim min cheol lee Hyun Jung Kim Guem San lee Hyungwoo Kim Byung Joo Kim Division of Longevity and Biofunctional Medicine Healthy Aging Korean Medical Research CenterSchool of Korean MedicinePusan National University Wonkwang University College of Korean Medicine Division of Pharmacology School of Korean MedicinePusan National University

AIM To investigate the effects of Hwangryunhaedok-tang(HHT) on gastrointestinal(GI) motility in *** The effects of a boiling water extract of HHT(HHTE) on GI motility were investigated by calculating percent intestinal transit rates(ITR%) and gastric emptying(GE) values using Evans Blue and phenol red, respectively, in normal mice and in mice with experimentally induced GI motility dysfunction(GMD). In addition, the effects of the four components of HHT, that is, Gardeniae Fructus(GF), Scutellariae Radix(SR), Coptidis Rhizoma(CR), and Phellodendri Cortex(PC), on GI motility were also *** In normal ICR mice, ITR% and GE values were significantly and dose-dependently increased by the intragastric administration of HHTE(0.1-1 g/kg). The ITR% values of GMD mice were significantly lower than those of normal mice, and these reductions were significantly and dose-dependently inhibited by HHTE(0.1-1 g/kg). Additionally, GF, CR, and PC dosedependently increased ITR% and GE values in normal and GMD *** These results suggest that HHT is a novel candidate for the development of a gastroprokinetic agent for the GI tract.

关键词： Hwangryunhaedok-tang Gastrointestinal motility Intestinal transit rate Gastric emptying Gastroprokinetic

Chronic venous insufficiency, could it be one of the missing pieces in the puzzle of treating pain?

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World Journal of Clinical Cases 2024年第1期12卷 232-235页

作者： min cheol Chang Department of Physical Medicine and Rehabilitation Yeungnam University HospitalDaegu 705-717South Korea

Pain is a common complaint among patients seeking medical *** left un-treated,pain can become chronic,significantly affecting patients’quality of *** accurate diagnosis of the underlying cause of pain is crucial for effective *** venous insufficiency(CVI)is frequently overlooked by pain ***,many pain physicians lack sufficient knowledge about *** is a common condition resulting from malfunctioning or damaged valves in lower limb *** of CVI,ranging from mild to severe,include pain,heaviness,fatigue,itching,swelling,skin color changes,and ulcers in the lower ***,it has become more widely known that these symptoms can be attributed to *** slight or mild CVI can cause related *** physicians primarily consider neuromusculoskeletal disorders when assessing patients with leg pain,and often neglect the possibility of *** clinical practice,when pain physicians encounter patients with unresolved leg pain,they must assess whether the patients exhibit symptoms of CVI and conduct tests to differ-entiate CVI from other potential causes.

关键词： Pain Chronic venous insufficiency Diagnosis Treatment Vein

Use of artificial intelligence in the field of pain medicine

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World Journal of Clinical Cases 2024年第2期12卷 236-239页

作者： min cheol Chang Department of Physical Medicine and Rehabilitation College of MedicineYeungnam UniversityDaegu 705-717South Korea

In this editorial we comment on the article“Potential and limitations of ChatGPT and generative artificial intelligence in medial safety education”published in the recent issue of the World Journal of Clinical *** article described the usefulness of artificial intelligence(AI)in medial safety ***,we focus specifically on the use of AI in the field of pain *** technology has emerged as a powerful tool,and is expected to play an important role in the healthcare sector and significantly contribute to pain medicine as further developments are *** may have several applications in pain ***,AI can assist in selecting testing methods to identify causes of pain and improve diagnostic *** of a patient’s symptoms into the algorithm can prompt it to suggest necessary tests and possible *** on the latest medical information and recent research results,AI can support doctors in making accurate diagnoses and setting up an effective treatment ***,AI assists in interpreting medical *** neural and musculoskeletal disorders,imaging tests are of vital *** can analyze a variety of imaging data,including that from radiography,computed tomography,and magnetic resonance imaging,to identify specific patterns,allowing quick and accurate image ***,AI can predict the outcomes of pain treatments,contributing to setting up the optimal treatment *** predicting individual patient responses to treatment,AI algorithms can assist doctors in establishing a treatment plan tailored to each patient,further enhancing treatment *** efficient utilization of AI in the pain medicine field,it is crucial to enhance the accuracy of AI decision-making by using more medical data,while issues related to the protection of patient personal information and responsibility for AI decisions will have to be *** the future,AI technology is expected to be innovatively applied in the field of

关键词： Artificial intelligence Pain medicine Diagnosis Prediction Image

Management of lymphedema is really a matter in patients with breast cancer

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World Journal of Clinical Cases 2024年第15期12卷 2482-2486页

作者： Jung Eun Choi min cheol Chang Department of Surgery College of MedicineYeungnam UniversityDaegu 705-717South Korea Department of Physical Medicine and Rehabilitation College of MedicineYeungnam UniversityDaegu 705-717South Korea

Lymphedema is a prevalent complication affecting patients with breast cancer,greatly impacting their quality of *** editorial describes diagnostic methods and therapeutic interventions for managing lymphedema in patients with breast *** relies on clinical evaluation and objective measures,including arm circumference and volumetric assessments,along with lymphoscintigraphy and ultrasonic *** primarily involves complex decongestive physical therapy,comprising manual lymphatic drainage,compression therapy,exercise,and meticulous skin *** interventions aim to reduce swelling,alleviate discomfort,and prevent further ***,lifestyle modifications such as avoiding extreme temperatures and maintaining proper hygiene are *** can be used for drug *** its prevalence,lymphedema often receives inadequate attention in clinical practice,emphasizing the importance of raising awareness and enhancing medical services for affected *** play a pivotal role in educating patients about preventive measures and ensuring timely ***,a comprehensive approach encompassing early diagnosis,multidisciplinary management,and patient education is essential to mitigate the burden of lymphedema in patients with breast cancer and improve their overall well-being.

关键词： Lymphedema Breast cancer Complex decongestive physical therapy Diagnosis Treatment

Chemical and mechanical properties of stainless, environment-friendly, and nonflammable Mg alloys (SEN alloys): A review

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Journal of Magnesium and Alloys 2024年第3期12卷 841-872页

作者： Jong Un lee Hyun Ji Kim Sang-cheol Jin Ye Jin Kim Young min Kim Bong Sun You Jun Ho Bae Sung Hyuk Park Advanced Metals Division Korea Institute of Materials ScienceChangwon 51508Republic of Korea Department of Materials Science and Metallurgical Engineering Kyungpook National UniversityDaegu 41566Republic of Korea Missile Research Institute Agency for Defense DevelopmentDaejeon 34060Republic of Korea

This review article provides overall understanding of stainless,environment-friendly,and nonflammable Mg alloys(SEN alloys)recently developed at the Korea Institute of Materials *** alloys are produced by adding small amounts of Ca and Y(eachminor amounts of Ca and Y renders excellent mechanical properties due to improved strengthening *** enhanced properties are attributed to more pronounced dynamic recrystallization and grain refining behaviors caused by the second-phase particles during extrusion.(4)Despite the presence of various types of second-phase particles,the fatigue properties of SEN9 alloys are similar to those of commercial AZ91 alloys.(5)Simultaneous introduction of Ca and Y suppresses the formation of Mg17Al12 discontinuous precipitates during aging,leading to the enhanced elongation of aged SEN alloys.(6)Adding mischmetal into the SEN9 alloy leads to a six-fold enhancement in ***,the studies conducted on SEN alloys demonstrate their excellent ignition and corrosion resistances and mechanical properties,which broaden the industrial applications of Mg alloys by addressing their inherent weaknesses.

关键词： SEN magnesium alloy Corrosion resistance Ignition resistance Mechanical properties Extrudability.

Pulsed laser interference patterning of transition-metal carbides for stable alkaline water electrolysis kinetics

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Carbon Energy 2024年第5期6卷 65-80页

作者： Yewon Oh Jayaraman Theerthagiri Ahreum min cheol Joo Moon Yiseul Yu Myong Yong Choi Department of Chemistry(BK21 FOUR) Research Institute of Natural SciencesGyeongsang National UniversityJinjuRepublic of Korea Core−Facility Center for Photochemistry and Nanomaterials Gyeongsang National UniversityJinjuRepublic of Korea

We investigated the role of metal atomization and solvent decomposition into reductive species and carbon clusters in the phase formation of transition-metal carbides(TMCs;namely,Co_(3)C,Fe_(3)C,TiC,and MoC)by pulsed laser ablation of Co,Fe,Ti,and Mo metals in *** interaction between carbon s-p-orbitals and metal d-orbitals causes a redistribution of valence structure through charge transfer,leading to the formation of surface defects as observed by X-ray photoelectron *** defects influence the evolved TMCs,making them effective for hydrogen and oxygen evolution reactions(HER and OER)in an alkaline ***_(3)C with more oxygen affinity promoted CoO(OH)intermediates,and the electrochemical surface oxidation to Co_(3)O_(4)was captured via in situ/operando electrochemical Raman probes,increasing the number of active sites for OER *** with more d-vacancies exhibits strong hydrogen binding,promoting HER kinetics,whereas Fe_(3)C and TiC with more defect states to trap charge carriers may hinder both OER and HER *** results show that the assembled membrane-less electrolyzer with Co_(3)C∥Co_(3)C and MoC∥MoC electrodes requires~2.01 and 1.99 V,respectively,to deliver a 10 mA cm−2 with excellent electrochemical and structural *** addition,the ascertained pulsed laser synthesis mechanism and unit-cell packing relations will open up sustainable pathways for obtaining highly stable electrocatalysts for electrolyzers.

关键词： acetone H_(2)and O_(2)evolution reactions pulsed laser ablation surface defects transition-metal carbides water electrolyzer

Weighted Forwarding in Graph Convolution Networks for Recommendation Information Systems

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Computers, Materials & Continua 2024年第2期78卷 1897-1914页

作者： Sang-min lee Namgi Kim Department of Computer Science Kyonggi UniversitySuwonKorea

Recommendation Information Systems(RIS)are pivotal in helping users in swiftly locating desired content from the vast amount of information available on the *** Convolution Network(GCN)algorithms have been employed to implement the RIS ***,the GCN algorithm faces limitations in terms of performance enhancement owing to the due to the embedding value-vanishing problem that occurs during the learning *** address this issue,we propose a Weighted Forwarding method using the GCN(WF-GCN)*** proposed method involves multiplying the embedding results with different weights for each hop layer during graph *** applying the WF-GCN algorithm,which adjusts weights for each hop layer before forwarding to the next,nodes with many neighbors achieve higher embedding *** approach facilitates the learning of more hop layers within the GCN *** efficacy of the WF-GCN was demonstrated through its application to various *** the MovieLens dataset,the implementation of WF-GCN in LightGCN resulted in significant performance improvements,with recall and NDCG increasing by up to+163.64%and+132.04%,***,in the *** dataset,LightGCN using WF-GCN enhanced with WF-GCN showed substantial improvements,with the recall and NDCG metrics rising by up to+174.40%and+169.95%,***,the application of WF-GCN to Self-supervised Graph Learning(SGL)and Simple Graph Contrastive Learning(SimGCL)also demonstrated notable enhancements in both recall and NDCG across these datasets.

关键词： Deep learning graph neural network graph convolution network graph convolution network model learning method recommender information systems

Effects of low molecular weight polysaccharide from Sargassum thunbergii against palmitic acid-induced intracellular lipid accumulation in 3T3-L1 adipocyte and HepG2 cells

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Food Science and Human Wellness 2024年第4期13卷 2244-2252页

作者： Hyo-Geun lee D.P.Nagahawatta M.J.M.S.Kurera Kyung-Mo Song Yun-Sang Choi You-Jin Jeon min-cheol Kang Department of Marine Life Sciences Jeju National UniversityJeju 63243Republic of Korea Department of Biotechnology Faculty of Agriculture and Plantation ManagementWayamba University of Sri LankaMakanduraGonawila(NWP)60170Sri Lanka Research Group of Food Processing Korea Food Research Institute245Wanju 55365Republic of Korea

Low molecular weight polysaccharides can be isolated from Sargassum thunbergii(LMPST)and in vitro experiments were conducted to evaluate the inhibitory effects on *** natures of LMPST were attained from *** and appraised their LMPST on palmitic acid(PA)induced lipid accretion in Hep G2,and 3T3-L1 *** treatment lessened lipid deposition and intracellular free fatty acid and triglyceride intensities in PA-treated above mentioned *** mechanistic study publicized that LMPST2 significantly suppressed adipogenesis and stimulated the PA-treated 3T3-L1 cells occupied in the lipolysis ***,in PA-treated Hep G2 cells,the free fatty acid oxidation was significantly increased by *** these constructive properties of LMPST2 from ***,is a potential candidate for diminishing the intracellular lipids,and for a therapeutic agent in those conditions.

关键词： Sargassum thunbergii Low molecular weight polysaccharide Lipid accumulation Obesity Liver steatosis