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Analysis of status and influencing factors of mental health in patients with systemic lupus erythematosus

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World Journal of Psychiatry 2024年第6期14卷 829-837页

作者： Xuan Zhang Zhe Wang Gui-Ling Lin Fang-Zhi Wei Yan-Ping Zhuang Wen-Lu Xu Qi Zhang Hui-Tao Wu Zi-Man He Xi-Yu Yin Ying Liu Long Mi Ai-min gong School of Traditional Chinese Medicine Hainan Medical UniversityHaikou 571101Hainan ProvinceChina Department of Rheumatology and Immunology Hainan General HospitalHainan Affiliated Hospital of Hainan Medical UniversityHaikou 570311Hainan ProvinceChina Department of Radiology The First Affiliated Hospital of Hainan Medical UniversityHainan Medical UniversityHaikou 570100Hainan ProvinceChina

BACKGROUND Systemic lupus erythematosus(SLE)is a heterogeneous autoimmune disorder with varied clinical courses and prognoses,not only did the patients suffer from physical impairment,but also various physical and psychiatric *** evidence have suggested that mental disorders in SLE patients,can lead to various adverse *** To explored the features and influencing factors of mental health in patients with SLE and clarifying the correlations between mental health and personality characteristics and perceived social *** results would provide a basis for psychological intervention in patients with *** The clinical data of 168 patients with SLE admitted at the First Affiliated Hospital of Hainan Medical University between June 2020 and June 2022 were *** assessment and correlation analysis were conducted using the Symptom Checklist-90(SCL-90)and Perceived Social Support Scale,and the collected data were compared with the national norms in *** relevant factors influencing mental health were identified by statistical analysis.A general information questionnaire,the Revised Life Orientation Test,and Short-Form 36-Item Health Survey were employed to assess optimism level and quality of life(QoL),*** Patients with SLE obtained higher scores for the somatization,depression,anxiety,and phobic anxiety subscales than national norms(P<0.05).A correlation was identified between total social support and total SCL-90 score or each subscale(P<0.05).The factors significantly affecting patients’mental health were hormone dosage and disease activity index(DAI)(P<0.05).The average optimism score of patients with SLE was 14.36±4.42,and 30 cases were in the middle and lower levels.A positive correlation was found between optimism level and QoL *** Patients with SLE develop psychological disorders at varying degrees,which are significantly influenced by hormone dosage and ***’menta

关键词： Systemic lupus erythematosus Mental health Quality of life Influencing factors

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自适应广义酉变换近似消息传递算法

清华大学学报（自然科学版） 2024年第4期64卷 700-711页

作者：雷旭鹏杨健徐孟怀朱江龚旻浙江大学海洋学院舟山316021 中国运载火箭技术研究院北京100076

信号/参数经过线性变换,再经过逐位非线性变换得到测量值的过程可以抽象为广义线性模型。广义近似消息传递算法是处理广义线性模型的一种Bayes方法,通过引入信号的稀疏先验分布,利用似然函数和先验分布得到后验均值和后验方差。然而,当... 详细信息

信号/参数经过线性变换,再经过逐位非线性变换得到测量值的过程可以抽象为广义线性模型。广义近似消息传递算法是处理广义线性模型的一种Bayes方法,通过引入信号的稀疏先验分布,利用似然函数和先验分布得到后验均值和后验方差。然而,当测量矩阵的元素不服从次Gauss分布时,广义近似消息传递算法性能会急剧恶化。通过奇异值分解,广义酉变换近似消息传递算法消除了测量矩阵的相关性,在包括相关测量矩阵的各类测量矩阵中表现出更强的鲁棒性。然而,经过足够多次迭代后,广义酉变换近似消息传递算法的信号重构误差在平衡点附近振荡;且随着测量矩阵相关性的增加,广义酉变换近似消息传递算法性能开始恶化。为了进一步提高广义酉变换近似消息传递算法的稳健性、改善算法准确性,该文提出自适应广义酉变换近似消息传递算法。该算法通过构造目标函数并自适应选择合适的步长,使得广义酉变换近似消息传递算法能够收敛到平衡点,从而获得更好的性能。大量的数值仿真实验结果验证了自适应广义酉变换近似消息传递算法的有效性。

关键词：广义线性模型压缩感知酉变换近似消息传递自适应算法

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肉制品中残留物检测技术的应用研究进展

现代食品 2024年第6期30卷 16-18页

作者：公民山东农业大学食品科学与工程学院山东泰安271000

本文阐述了残留检测技术在肉制品中的应用研究进展,介绍了残留检测技术在肉制品中的重要性,概括了目前常用的残留检测技术,总结了残留检测技术的发展趋势和未来研究方向,旨在为相关领域的研究提供参考。

关键词：残留检测技术肉制品兽药残留农药残留添加剂残留

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基于铁电材料的有机光电突触晶体管研究

半导体光电 2024年第1期45卷 49-55页

作者：王荃田龚敏张嗣杰四川大学物理学院成都610064 贵州工程应用技术学院贵州毕节551700

模拟生物突触结构的设备是实现神经网络计算的可行方案之一,其中人工视网膜器件为机器视觉和图像识别的实现提供了有力支持。通过旋涂制备聚偏氟乙烯-三氟乙烯(P(VDF-TrFE))制备铁电栅层,热蒸发酞菁铜(CuPc)作为半导体层,探究该晶体管... 详细信息

模拟生物突触结构的设备是实现神经网络计算的可行方案之一,其中人工视网膜器件为机器视觉和图像识别的实现提供了有力支持。通过旋涂制备聚偏氟乙烯-三氟乙烯(P(VDF-TrFE))制备铁电栅层,热蒸发酞菁铜(CuPc)作为半导体层,探究该晶体管模拟突触功能的光电响应。实验结果表明,该光电晶体管在625 nm具有显著的光响应,其能够产生兴奋性突触后电流(EPSC)并实现短期可塑性到长期可塑性的转变以及高通滤波功能。利用剩余极化强度模拟了大脑学习过程中提前施加注意的行为。此外,以栅电压和光照作为独立输入逻辑信号,在单个晶体管中实现了“与”和“或”的布尔逻辑功能。上述结果表明,CuPc可以与铁电材料进行良好结合并制备出具有突触响应特点的光电晶体管,这为人工视网膜器件的开发提供了有机铁电器件的参考。

关键词：有机铁电突触光电调节逻辑门人工视觉能带结构

尼可地尔对老年AMI患者PCI术后造影剂诱导急性肾损伤的保护作用

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临床急诊杂志 2024年第1期25卷 13-18页

作者：龚敏朱亮丁士勤安徽理工大学附属新华医院(淮南新华医院)心内科安徽淮南232052

目的:探究尼可地尔对老年急性心肌梗死(acute myocardial infarction,AMI)患者经皮冠状动脉介入治疗(percutaneous coronary intervention,PCI)术后造影剂诱导急性肾损伤的保护作用。方法:选取2019年9月—2021年10月住院行PCI术的老年AMI患者141例,随机分为对照组、尼可地尔低剂量组和尼可地尔高剂量组,每组47例;对照组患者接受常规治疗方案(阿司匹林+氯吡格雷+水化治疗),尼可地尔低剂量组和尼可地尔高剂量组在对照组基础上,术前30 min至术后3 d服用尼可地尔,3次/d,低剂量组5 mg/次,高剂量组为10 mg/次。比较各组患者肾功能指标、氧化应激指标、炎性指标、核因子-E2相关因子2(nuclear factor erythtoid 2 related factor 2,Nrf2)/抗氧化响应元件(antioxidant response element,ARE)信号通路基因mRNA相对表达水平及造影剂诱导的急性肾损伤发生率。结果:各组造影剂诱导的急性肾损伤发生率比较,对照组明显高于尼可地尔低剂量组和尼可地尔高剂量组,差异有统计学意义(P0.05)。结论:尼可地尔可能对老年AMI患者PCI术后造影剂诱导的急性肾损伤具有保护作用,可能与尼可地尔调节Nrf2/ARE信号通路,发挥抗氧化应激及抗炎作用有关。

关键词：尼可地尔急性心肌梗死老年患者造影剂急性肾损伤

Indoleamine 2,3-dioxygenase and regulatory dendritic cells contribute to the allograft protection induced by infusion of donor-specific splenic stromal cells

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Cellular & Molecular Immunology 2011年第1期8卷 31-40页

作者： Li Liu Lihua Duan min gong Hong Dai Quan gong Fang Zheng Zheng Tan Congyi Wang Feili gong min Fang Laboratory of Transplantation Department of ImmunologyTongji Medical College of Huazhong University of Science and TechnologyWuhanChina The Center for Biomedical Research Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanChina

It has been reported that splenic stromal cells(SSCs)are capable of directly supporting the development of CD11c ^(lo)CD45RB^(+) IL-10-producing dendritic cells(DCs)from lineage-negative c-kit^(+) progenitor cells in the absence of exogenous *** vitro,DCs that differentiate on stromal cells suppress mixed leukocyte reaction responses and induce primary alloreactive CD4^(+) T cells to differentiate into IL-10-producing Tr1 ***,the precise mechanisms by which these SSCs exert their regulatory functions in vivo remain ***,their possible contribution to the development of allograft transplantation tolerance has yet to be ***,we have used both murine skin and cardiac allograft transplantation models to explore whether in vivo alloresponses can be regulated by infusion with donor-derived SSCs and to investigate the possible mechanisms by which SSCs exert regulatory effects to prevent allograft *** show that intravenous SSC infusion prolonged murine skin allograft *** prolonged graft survival is associated with augmentation of the generation of regulatory DC subsets and CD4^(+) CD25^(+) Foxp3^(+) regulatory T cells(Tregs),as well as upregulation of the production of suppressive cytokines IL-10 and transforming growth factor(TGF)-***,we found that indoleamine 2,3-dioxygenase and SSC-derived regulatory DCs contribute to allograft protection by infusion of donor-specific *** data suggest that donor-derived SSCs could be used as a therapeutic target to promote transplantation tolerance.

关键词： dendritic cell indoleamine 2,3-dioxygenase splenic stromal cell transplantation

基于卷积注意力机制的锂离子电池剩余使用寿命预测研究

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西南民族大学学报（自然科学版） 2024年第3期50卷 336-346页

作者：史云汪立伟公岷西南民族大学电子信息学院四川成都610041

锂离子电池剩余使用寿命的准确估计和预测对于锂离子电池电源管理系统有着重要的意义.一方面能够提高实际电路系统的可靠性,同时能够延长电池的使用寿命.锂离子电池的退化过程表现出复杂、非线性特征且伴随容量再生现象,导致传统预测模... 详细信息

锂离子电池剩余使用寿命的准确估计和预测对于锂离子电池电源管理系统有着重要的意义.一方面能够提高实际电路系统的可靠性,同时能够延长电池的使用寿命.锂离子电池的退化过程表现出复杂、非线性特征且伴随容量再生现象,导致传统预测模型对锂离子电池剩余使用寿命预测(Remaining Useful Life,RUL)准确性低.为进一步提升锂离子电池RUL的预测精度,首先深入分析电池历史退化数据,构建一种新的基于卷积注意力机制深度学习框架.通过对锂离子电池老化循环过程的研究,选取容量数据作为健康因子(Health Indicator,HI),利用卷积神经网络(Convolu⁃tional Neural Network,CNN)的卷积和池化操作挖掘数据内在信息,降低数据复杂度,提取电池数据的时序特征.并将特征数据输出到构建的注意力机制(Attention Mechanism,AM)深度网络,捕捉全局时序数据的位置信息和分析时序数据中内部信息的关系,以此获得准确的RUL预测.最后使用公开的NASA和CALCE数据集上进行验证,并对比其他几种预测模型,结果表明所提出模型的具有较高预测精度和泛化适应能力.

关键词：锂电池剩余使用寿命健康因子卷积注意力机制注意力神经网络

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High temperature property studies of the 6H-SiC MOS capacitor

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Science China(Physics,Mechanics & Astronomy) 2011年第1期54卷 95-97页

作者： MU WeiBing gong min CAO Qun School of Physical Science and Technology Sichuan University Chengdu 610064 China Institute of Electricity Engineering CAEP Mianyang 621900 China Key Laboratory of Radiation Physics and Technology (Sichuan University) Ministry of Education Chengdu 610064 China

N-type and p-type 6H-SiC metal oxide semiconductor (MOS) capacitor samples are fabricated with a typical method,and the high frequency capacitor voltage (C-V) curves of these samples are measured at temperatures ranging from 293 to 533 *** exists huge difference between the n-type and p-type ***-band voltage shift of the n-type sample becomes larger with temperature rising,but that of the p-type sample have very little *** may be caused by the residual Al in the p-type *** types of the SiC samples follow the same rule of flat-band voltage changing with *** their mechanisms are different as temperature is above 453 *** both types the p-type SiC is more suitable for high temperature applications.

关键词： high temperature 6H-SiC MOS capacitor flat-band voltage

Linear Network Coding Based Fast Data Synchronization for Wireless Ad Hoc Networks with Controlled Topology

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China Communications 2022年第5期19卷 46-53页

作者： Die Hu Xuejun Zhu min gong Shaoshi Yang School of Information and Communication Engineering Beijing University of Posts and TelecommunicationsBeijing 100876China China Academy of Launch Vehicle Technology Beijing 100076China Key Laboratory of Universal Wireless Communications Ministry of EducationBeijing 100876China

Fast data synchronization in wireless ad hoc networks is a challenging and critical *** is fundamental for efficient information fusion,control and decision in distributed ***,distributed data synchronization was mainly studied in the latency-tolerant distributed databases,or assuming the general model of wireless ad hoc *** this paper,we propose a pair of linear network coding(NC)and all-to-all broadcast based fast data synchronization algorithms for wireless ad hoc networks whose topology is under operator’s *** consider both data block selection and transmitting node selection for exploiting the benefits of *** of using the store-and-forward protocol as in the conventional uncoded approach,a compute-and-forward protocol is used in our scheme,which improves the transmission *** performance of the proposed algorithms is studied under different values of network size,network connection degree,and per-hop packet error *** results demonstrate that our algorithms significantly reduce the times slots used for data synchronization compared with the baseline that does not use NC.

关键词： all-to-all broadcast data synchronization distributed system network coding wireless ad hoc network UAV