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dryland agriculture and rangeland restoration priorities in Afghanistan

Journal of Arid Land 2015年第3期7卷 391-402页

作者： michael J JACOBS Catherine A SCHLOEdER Philip d TANIMOTO Texas Agri Life Research Department of Ecosystem Science & Management2138TAMUCollege StationTX 77843-2138USA Oikos Services LLCFortineMT 59918USA Conservation Imaging Inc.AuburndaleMassachusetts 02466USA

Afghanistan is threatened by rangeland degradation.A quantitative visual analysis of Google Earth Imagery was used to systematically locate,characterize and quantify the current extent of rangelands in Afghanistan degraded as a consequence of dryland *** data were used in conjunction with dryland agriculture locations to establish a climate envelope comprised by temperature and mean annual precipitation to create a geographical mask known to contain dryland *** this mask we created a grid of 100 km2 cells that we analyzed individually to access dryland agriculture *** limits to sustainable dryland agriculture and areas of high restoration priority were also assessed as was the distribution of rain-fed agriculture with respect to the location of traditional migration routes for extensive livestock *** extents of agriculture in Afghanistan,at both upper and lower elevations,correlated most closely with mean annual temperature（MAT） at the upper elevation limits,and with mean annual precipitation（MAP） at the lower elevation *** total,dryland agriculture comprised 38,980 km2 of former native *** was highest in the northwestern,northern and northeastern provinces of Herat,Badghis,Faryab,Jawzjan,Sar-e-Pul,Samangan,Balkh,Baghlan,Kunduz,Takhar and Badakhshan,with the highest percentage of conversion occurring in *** MAP value of 〈400 mm is perceived by farmers as the current climatic limit to sustainable dryland agriculture across the northern regions of the *** this MAP value,approximately 27,677 km2 of converted rangeland met the need for restoration *** projections indicate that Afghanistan will become warmer and drier in the coming *** consequence of this trend is that the MAP threshold of 〈400 mm to sustainable dryland agriculture will become obsolete in the coming *** of currently converted rangelands is needed to restore critical grazing area

关键词： degradation climatic trends extensive livestock production dryland agriculture rangeland restoration

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diversity of Gene Expression in Hepatocellular Carcinoma Cells

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Genomics, Proteomics & Bioinformatics 2015年第6期13卷 377-382页

作者： Fan Zhang Li Cui michael d.Kuo department of Molecular and Medical Genetics University of North Texas Health Science Center department of Neurosciences School of Medicine University of California department of Radiological Sciences University of California Los Angeles David Geffen School of Medicine

Understanding tumor diversity has been a long-lasting and challenging question for researchers in the field of cancer heterogeneity or tumor evolution. Studies have reported that com- pared to normal cells, there is a higher genetic diversity in tumor cells, while higher genetic diversity is associated with higher progression risks of tumor. We thus hypothesized that tumor diversity also holds true at the gene expression level. To test this hypothesis, we used t-test to compare the means of Simpson＇s diversity index for gene expression （SdIG） between tumor and non-tumor samples. We found that the mean SdIG in tumor tissues is significantly higher than that in the non-tumor or normal tissues （P 〈 0.05） for most datasets. We also combined microarrays and next-generation sequencing data for validation. This cross-platform and cross-experimental validation greatly increased the reliability of our results.

关键词： Gene expression Hepatocellular carcinomacell diversity Mieroarray Next-generation sequencing

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Utilizing multiphoton imaging and integrative clearing to reveal sex differences in neuroimmune interactions after nerve injury

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Neural Regeneration Research 2022年第11期17卷 2429-2430页

作者： Zachary W.Castillo michael d.Burton Neuroimmunology and Behavior Laboratory Department of NeuroscienceSchool of Behavioral and Brain SciencesCenter for Advanced Pain StudiesUniversity of Texas at Dallas

With the constant development of multiphoton microscopy,our ability to observe complex and dynamic biological processes deeper within living tissue,is steadily *** use multiphoton microscopy,because experiments can be conducted with little to no invasiveness or tissue damage over a long period of time with no photodamage(Mancuso et al.,2009).This allows for the introduction of tissue into the context of a three-dimensional 3d environment in which visualization of cellular activation and interaction is *** circumventing a distorted reconstruction with limited z-stacks,multiphoton imaging provides enhanced spatiotemporal resolution.

关键词： resolution. multiphoton distorted

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Effects of temperature and SO_3 on re-emission of mercury from activated carbon under flue gas conditions

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Journal of Environmental Sciences 2019年第5期31卷 67-73页

作者： michael Royko Benjamin Galloway Noah d.Meeks Bihter Padak department of Chemical Engineering University of South Carolina Southern Company Services Inc.600 18th Street North

Mercury(Hg) is a toxic and bio-accumulating heavy metal that is predominantly released via the combustion of coal. due to its toxicity, the Environmental Protection Agency(EPA)has introduced Mercury and Air Toxics Standards(MATS) Rule regarding allowable Hg emissions. In order to reduce emissions, power plants have widely adopted activated carbon(AC) injection. AC injection has proven to be an effective method to reduce Hg emissions, but the re-emission of previously adsorbed Hg during unit operation, likely due to changing temperature or flue gas composition, could be problematic. This study specifically examined the effects of temperature and sulfur trioxide(SO3) concentration,by ramping temperature and SO3 concentration independently and simultaneously, on AC samples that are already exposed to flue gas and saturated in presence of Hg, sulfur dioxide(SO2) and nitric oxide(NO). Of these two suspected factors to cause re-emission,temperature had the greater impact and resulted in re-emission of both elemental and oxidized Hg with a greater fraction of oxidized Hg, which can be attributed to elemental Hg being more strongly bonded to the AC surface. Surprisingly, exposing the samples to increasing concentrations of SO3 had nearly no effect under the conditions examined in this study, possibly as a result of the samples being already saturated with sulfur prior to the SO3 ramp tests to simulate transient conditions in the plant.

关键词： Mercury re-emission Sulfur trioxide Activated carbon

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The role of retinoic acid in the commitment to meiosis

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Asian Journal of Andrology 2021年第6期23卷 549-554页

作者： Rachel L Gewiss M Christine Schleif michael d Griswold School of Molecular Biosciences and Center for Reproductive Biology Washington State UniversityPullmanWA 99164USA

Male meiosis is a complex process whereby spermatocytes undergo cell division to form haploid *** review focuses on the role of retinoic acid(RA)in meiosis,as well as several processes regulated by RA before cell entry into meiosis that are critical for proper meiotic entry and ***,we discuss RA metabolism in the testis as well as the roles of stimulated by retinoic acid gene 8(STRA8)and MEIOSIN,which are responsive to RA and are critical for *** assert that transcriptional regulation in the spermatogonia is critical for successful meiosis.

关键词： meiosis retinoic acid spermatogenesis testis

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BMPRⅡ^(+)neural precursor cells isolated and characterized from organotypic neurospheres:an in vitro model of human fetal spinal cord development

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Neural Regeneration Research 2024年第2期19卷 447-457页

作者： michael W.Weible II michael d.Lovelace Hamish d.Mundell Tsz Wai Rosita Pang Tailoi Chan-Ling Bosch Institute Discipline of Anatomy and Histology(F13)University of SydneySydneyNSWAustralia School of Environment and Science Griffith UniversityNathanQLDAustralia discipline of Medicine Nepean Clinical SchoolFaculty of Medicine and HealthUniversity of SydneyKingswoodNSWAustralia New South Wales Brain Tissue Resource Centre School of Medical SciencesFaculty of Medicine and HealthUniversity of SydneyCharles Perkins Centre(D17)SydneyNSWAustralia

Roof plate secretion of bone morphogenetic proteins(BMPs)directs the cellular fate of sensory neurons during spinal cord development,including the formation of the ascending sensory columns,though their biology is not well ***-ⅡBMP receptor(BMPRⅡ),the cognate receptor,is expressed by neural precursor cells during embryogenesis;however,an in vitro method of enriching BMPRⅡ^(+)human neural precursor cells(hNPCs)from the fetal spinal cord is *** was undertaken on intact second-trimester human fetal spinal cord using antibodies to BMPRⅡand leukemia inhibitory factor(LIF).Regions of highest BMPRⅡ^(+)immunofluorescence localized to sensory *** and meningeal-associated BMPRⅡ^(+)vascular cells were identified in both intact fetal spinal cord and cortex by co-positivity with vascular lineage markers,Cd34/*** immunostaining identified a population of somas concentrated in dorsal and ventral horn interneurons,mirroring the expression of LIF receptor/Cd118.A combination of LIF supplementation and high-density culture maintained culture growth beyond 10 passages,while synergistically increasing the proportion of neurospheres with a stratified,*** neurospheres were characterized by BMPRⅡ^(+)/MAP2ab^(+/–)/βⅢ-tubulin^(+)/nestin^(–)/vimentin^(–)/GFAP^(–)/NeuN^(–)surface hNPCs surrounding a heterogeneous core ofβⅢ-tubulin^(+)/nestin^(+)/vimentin^(+)/GFAP^(+)/MAP2ab^(–)/NeuN^(–)multipotent *** cultures from tripotential neurospheres contained neuronal(βⅢ-tubulin^(+)),astrocytic(GFAP+),and oligodendrocytic(O4+)lineage ***-activated cell sorting-sorted BMPRⅡ^(+)hNPCs were MAP2ab^(+/–)/βⅢ-tubulin^(+)/GFAP^(–)/O4^(–)in *** is the first isolation of BMPRⅡ^(+)hNPCs identified and characterized in human fetal spinal *** data show that LIF combines synergistically with high-density reaggregate cultures to support the organotypic reorganization of neurospheres,characterize

关键词： BMPRⅡ bone morphogenetic protein histotypic human spinal cord development leukemia inhibitory factor neurosphere organotypic reaggregate sensory columns

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Functional group resolved NMR relaxation of 3-carbon adsorbates in mesoporous alumina

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Magnetic Resonance Letters 2023年第3期3卷 248-255,I0004页

作者： Neil Robinson Carmine d’Agostino michael LJohns department of Chemical Engineering The University of Western Australia35 Stirling HighwayPerthWA 6009Australia department of Chemical Engineering The University of ManchesterOxford RoadManchesterM139PLUK dipartimento di Ingegneria Civile ChimicaAmbientale e Dei Materiali(DICAM)Alma Mater Studiorum e Universita di BolognaVia Terracini28Bologna40131Italy

NMR relaxation analysis provides a unique and non-invasive probe of fluid dynamics within porous materials,and may be applied to the interpretation of a wide variety of material and interfacial ***,we report two-dimensional^(1)H T_(1)-T_(2)relaxation correlation measurements of a range of three-carbon adsorbates(1-propanol,2-propanol and propanoic acid)imbibed within the mesoporous metal oxide *** data,acquired across field strengths of 2 MHz,12.7 MHz and 43 MHz,clearly reveal two populations in each measurement,identified as the alkyl and hydroxyl moieties of each *** results expand the range of materials in which such functional group resolved relaxation is known to occur,and demonstrate the clear persistence of such phenomena using a range of typical benchtop NMR systems employed to study fluid-saturated porous media.

关键词： NMR relaxation Adsorption Porous media Low-field NMR

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Primary gastric non-Hodgkin lymphomas:Recent advances regarding disease pathogenesis and treatment

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World Journal of Gastroenterology 2021年第35期27卷 5932-5945页

作者： michael d diamantidis Maria Papaioannou Evdoxia Hatjiharissi department of Hematology Thalassemia and Sickle Cell Disease UnitGeneral Hospital of LarissaLarissa 41221ThessalyGreece division of Hematology First Department of Internal MedicineAHEPA General HospitalAristotle University of ThessalonikiThessaloniki 54636Greece

Primary gastric lymphomas(PGLs)are distinct lymphoproliferative neoplasms described as heterogeneous entities clinically and *** main histological types are diffuse large B-cell lymphoma(dLBCL)or mucosaassociated lymphoma *** has been one of the main fields of clinical research of our group in recent *** gastric dLBCLs are frequent,sufficient data to guide optimal care are *** today,a multidisciplinary approach has been applied,including chemotherapy,surgery,radiotherapy or a combination of these *** this minireview article,we provide an overview of the clinical manifestations,diagnosis and staging of these diseases,along with their molecular pathogenesis and the most important related clinical published *** then discuss the scientific gaps,perils and pitfalls that exist regarding the aforementioned studies,in parallel with the unmet need for future research and comment on the proper methodology for such retrospective *** to fill this gap,we retrospectively evaluated the trends in clinical presentation,management and outcome among 165 patients with dLBCL PGL who were seen in our institutions in *** study cohort was divided into two subgroups,comparing the main 2 therapeutic options[cyclophosphamide doxorubicin vincristine prednisone(CHOP)vs rituximab-CHOP(R-CHOP)].A better outcome with immunochemotherapy(R-CHOP)was *** the next 2 mo,we will present the update of our study with the same basic conclusion.

关键词： Primary gastric lymphoma Extranodal non-Hodgkin’s lymphoma diffuse large B-cell lymphoma Mucosa-associated lymphoid tissue Immunochemotherapy Rituximab-cyclophosphamide doxorubicin vincristine prednisone

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Phenotypic differences between coryneform bacteria isolated from seminal fluid of healthy men and men with chronic prostatitis syndrome

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Asian Journal of Andrology 2009年第4期11卷 517-520页

作者： Iuri B Ivanov Viktor A Gritsenko michael d Kuzmin department of Human Microbiology Institute of Cellular and Intracellular Symbiosis Russian Academy of Sciences Orenburg 460056 Russia

We compared the potential phenotypic properties of coryneform bacteria associated with chronic prostatitis syndrome （CPS）, such as secretory inhibitor of lysozyme （SIL） and secretory inhibitor of platelet microbicidal protein （SIPMP）. A total of 110 clinical isolates of coryneform bacteria isolated from the seminal fluid of healthy men and men with CPS were tested. SIPMP production was tested by inhibiting platelet microbicidal protein （PMP） bioactivity against Bacillus subtilis, and was expressed as percentage of inhibition of PMP bactericidal activity. SIL production was tested by inhibiting lysozyme activity against Micrococcus lysodeikticus and was expressed in microgram per millilitre of inactivated lysozyme. A significantly higher proportion of CPS strains （58.7% vs. 19.2 %） was SIPMP-positive compared with non-CPS strains （P 〈 0.01）. Of the CPS strains tested, 77.8% were SIL-positive compared with 34% of the non- CPS isolates （P 〈 0.05）. These results suggest that the diagnosis of CPS should not rely solely on classical parameters, for example, the identification and counting of microorganisms, but the functional significance of these parameters must be estimated, possibly by the concentration of different bacterial substrains, detection of opportunistic microorganisms with pathogenic properties, such as pronounced resistance to the cationic antimicrobial peptides, and/or the ability to inhibit the antimicrobial host defence factors.

关键词： Corynebacterium spp lysozyme platelet microbicidal protein prostatitis

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Statistical variability and fragility assessment of ballistic perforation of steel plates for 7.62 mm AP ammunition

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defence Technology（防务技术） 2020年第3期16卷 503-513页

作者： Mark G.Stewart michael dNetherton Centre for Infrastructure Performance and Reliability The University of NewcastleNew South Wales2038Australia

The paper describes field test results of 7.62×51 mm M61 AP(armour piercing) ammunition fired into mild steel targets at an outdoor *** targets varied from 10 mm to 32 mm in *** tests recorded penetration depth,probability of perforation(i.e.,complete penetration),muzzle and impact velocities,bullet mass,and plate yield strength and *** measured penetration depth exhibited a variability of approximately±12%.The paper then compared ballistic test results with predictive models of steel penetration depth and thickness to prevent *** parameters were derived for muzzle and impact velocity,bullet mass,plate thickness,plate hardness,and model error.A Monte-Carlo probabilistic analysis was then developed to estimate the probability of plate perforation of 7.62 mm M61 AP ammunition for a range of impact velocities,and for mild steels,and High Hardness Armour(HHA) *** perforation fragility analysis considered the random variability of impact velocity,bullet mass,plate thickness,plate hardness,and model *** a probabilistic analysis allows for reliability-based design,where,for example,the plate thickness with 95% reliability(*** 1 in 20 shots will penetrate the wall) can be estimated knowing the probabilistic distribution of ***,it was found that the plate thickness to ensure a low 5% probability of perforation needs to be 11-15% thicker than required to have a 50/50 chance of perforation for mild steel *** would need to be 20-30% thicker if probability of perforation is reduced to zero.

关键词： Ballistics Probability Statistics Steel plates Armour steel Ammunition Experimental Perforation

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