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Prospective,multicentre study of screening,investigation and management of hyponatraemia after subarachnoid haemorrhage in the UK and Ireland

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Stroke & Vascular Neurology 2023年第3期8卷 207-216,I0028-I0059页

作者： James J m Loan Steven tominey Kirun Baweja Julie Woodfield thomas J G chambers mark Haley Simran S Kundu H Y Josephine tang Anthony N Wiggins michael t c poon.paul m bren.an translational Neurosurgery The University of Edinburgh Centre for Clinical Brain SciencesEdinburghUK Neurosurgery NHS LothianEdinburghUK Neurosurgery Institute of Neurological SciencesGlasgowUK Department of medicine School of MedicineDentisty and NuringUniversity of GlasgowGlasgowUK Internal medicine Queen's UniversityKingstonOntarioCanada centre for Discovery Brain Sciences University of EdinburghEdinburghUK Edinburgh centre for Diabetes and Endocrinology NHS LothianEdinburghUK Radiology University Hospitals Plymouth NHS TrustPlymouthUK Department of medicine Cork University HospitalUniversity College CorkCorkIreland

Background Hyponatraemia often occurs after subarachnoid haemorrhage(SAH).However,its clinical significance and optimal management are *** audited the screening,investigation and management of hyponatraemia after *** We prospectively identified consecutive patients with spontaneous SAH admitted to neurosurgical units in the United Kingdom or *** reviewed medical records daily from admission to discharge,21 days or death and extracted all measurements of serum sodium to identify hyponatraemia(mmol/L).main outcomes were death/dependency at discharge or 21 days and admission duration>10 *** of hyponatraemia with outcome were assessed using logistic regression with adjustment for predictors of outcome after SAH and admission *** assessed hyponatraemia-free survival using multivariable cox *** 175/407(43%)patients admitted to 24 neurosurgical units developed hyponatraemia.5976 serum sodium measurements were *** osmolality,urine osmolality and urine sodium were measured in 30/166(18%)hyponatraemic patients with complete *** most frequently target daily fluid intake was>3 L and this did not differ during hyponatraemic or non-hyponatraemic episodes.26%(n/N=42/164)patients with hyponatraemia received sodium supplementation.133(35%)patients were dead or dependent within the study period and 240(68%)patients had hospital admission for over 10 *** the multivariable analyses,hyponatraemia was associated with less dependency(adjusted OR(aOR)=0.35(95%cI 0.17 to 0.69))but longer admissions(aOR=3.2(1.8 to 5.7)).World Federation of Neurosurgical Societies grade I-III,modified Fisher 2-4 and posterior circulation aneurysms were associated with greater hazards of *** In this comprehensive multicentre prospective-adjusted analysis of patients with SAH,hyponatraemia was investigated inconsistently and,for most patients,was not associated with changes in management or clinical outcome.t

关键词： admitted urine centre

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Generation and optical display of a binary-sampled phase-only hologram

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chinese Optics Letters 2016年第1期14卷 12-15页

作者： P. W. m. tsang Y.-t. chow t.-c. poon J.-P. Liu Department of Electronic Engineering City University of Hong Kong Hong Kong SAR China Bradley Department of Electrical and computer Engineering Virginia Tech Blacksburg VA 24061 USA Department of Photonics Feng Chia University No. 100 Wenhwa Rd. Taichung 407 China

Past research has demonstrated that a phase-only hologram can be obtained by down-sampling the intensity image of the object scene prior to the generation of the hologram. In this Letter, we extend the method to the generation of binary phase-only holograms. A hologram derived with our proposed method is referred to as a binary-sampled phase-only hologram （BSPOH）. Being different from the parent scheme, we have adopted an off- axis configuration in the generation of the BSPOH to avoid the quantization noise, the zeroth-order light, and the conjugate lights. An experimental evaluation reveals that the reconstructed image of the BSPOH is of good quality, and only contains slight amount of noise.

关键词： Bins Holographic displays Lithography

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tensorial tomographic Fourier ptychography with applications to muscle tissue imaging

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Advanced Photonics 2024年第2期6卷 50-60页

作者： Shiqi Xu Xi Yang paul Ritter Xiang Dai Kyung chul Lee Lucas Kreiss Kevin c.Zhou Kanghyun Kim Amey chaware Jadee Neff carolyn Glass Seung Ah Lee Oliver Friedrich Roarke Horstmeyer Duke University DurhamNorth CarolinaUnited States Friedrich-Alexander University ErlangenGermany Uc San Diego La JollaCaliforniaUnited States Yonsei University SeoulRepublic of Korea Uc Berkeley BerkeleyCaliforniaUnited States Duke University medical center DurhamNorth CarolinaUnited States

We report tensorial tomographic Fourier ptychography(t^(2)oFu),a nonscanning label-free tomographic microscopy method for simultaneous imaging of quantitative phase and anisotropic specimen information in *** upon Fourier ptychography,a quantitative phase imaging technique,t^(2)oFu additionally highlights the vectorial nature of *** imaging setup consists of a standard microscope equipped with an LED matrix,a polarization generator,and a polarization-sensitive *** tensors of anisotropic samples are computationally recovered from polarized intensity measurements across three *** demonstrate t^(2)oFu’s efficiency through volumetric reconstructions of refractive index,birefringence,and orientation for various validation samples,as well as tissue samples from muscle fibers and diseased heart *** reconstructions of healthy muscle fibers reveal their 3D fine-filament structures with consistent ***,we demonstrate reconstructions of a heart tissue sample that carries important polarization information for detecting cardiac amyloidosis.

关键词： computational imaging three-dimensional imaging phase retrieval microscopy polarization-sensitive imaging labelfree imaging

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An enhanced method for fast generation of hologram sub-lines

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chinese Optics Letters 2009年第12期7卷 1092-1096页

作者： P. W. m. tsang J. P. Liu K. W. K. cheung t.-c. poon Department of Electronic Engineering City University of Hong Kong Tat Chee Avenue Kowloon Hong Kong SAR China Department of Photonics Feng Chia University No. 100 Wenhwa Rd. Seatwen Taichung 40724 China Bradley Department of Electrical and computer Engineering Virginia Tech Blacksburg Virginia 24061 USA

Sub-lines are one-dimensional diffraction patterns representing the light beams emerging from horizontal planes of an object image. Past research has demonstrated that the sub-lines can be encapsulated as a multi-bank filtering process, and implemented with a field programmable gate array （FPGA） device. As the complexity of the filters is high, their length and the number of input pins have to be reduced substantially, hence leading to degradation on the reconstructed images. We propose an enhanced method to overcome the problem by binarizing the filters＇ coefficients, and half-toning the pixel intensities of the object image. Experimental evaluation reveals that our method results in reconstructed images are superior to that obtained with the parent method.

关键词： Diffraction Field programmable gate arrays (FPGA) Holographic interferometry

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Experimental Investigation of the Stability of the Performance characteristics of a Photovoltaic module in the Face of Environmental and meteorological Factors

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Open Journal of Applied Sciences 2024年第2期14卷 589-608页

作者： Adingra paul Arsène Kouassi Siaka touré Diakaridja traoré Laboratoire des Sciences de la matière de l’Environnement et de l’Energie Solaire (LASMES) Unité de Formation et de Recherche des Sciences des Structures de la Matière et Technologie (UFR-SSMT) Université Félix Houphou&#235t Boigny Abidjan C&#244te d’Ivoire

the explosive technological improvement of photovoltaic systems as well as the necessity of populations to come to less expensive energy sources, that have led to an implosion at the level of solar panel manufacturers. this causes a large flow of these equipments to developing countries where the need is high, without any quality control. that conducted an experimental investigation on the performance characteristics of a 250 wp monocrystalline silicon photovoltaic module in other to check the verification and quality control. most of these PV panels which often have missing informations are manufactured and tested in places that are inadequate for our environmental and meteorological conditions. Also, their influences on the stability of internal parameters were evaluated in order to optimize their performance. the results obtained at maximum illumination (1000 w/m2) confirmed those produced by the manufacturer. the analysis of these characteristics showed that the illumination and the temperature (meteorological factors) influenced at most the stability of the internal characteristics of the module in the sense that the maximum power increased very rapidly beyond 750 w/m2 but a degradation of performance was accentuated for a temperature of the solar cells exceeding 50°c. the degradation coefficients were evaluated at -0.0864 V/°c for the voltage and at -1.6248 w/°c for the power. the 10° inclination angle of the solar panel proved to be ideal for optimizing overall efficiency in practical situations.

关键词： Renewables Energies Instruments Internal Parameters of Photovoltaic Panel monocrystalline Photovoltaic Panel Solar Energy Production Energy Intermittence

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Review on theory and applications of wavefront recording plane framework in generation and processing of digital holograms

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chinese Optics Letters 2013年第1期11卷 18-24页

作者： P. W. m. tsang t.-c. poon Department of Electronic Engineering City University of Hong Kong Bradley Department of Electrical and computer Engineering

the wavefront recording plane （WRP）, subsequently generalized to be known as the virtual diffraction plane （VDP）, is a recent concept that has been successfully deployed in fast generation and processing of digital holograms. In brief, the WRP and its extension, the VDP, is a hypothetical plane that is located between the hologram and the object scene, and which is at close proximity to the latter. As such, the fringe patterns on the hypothetical plane are carrying the holistic information of the hologram, as well as the local optical properties of the object scene. this important property enables a hologram to be processed with classical image processing techniques that are normally unsuitable for handling holographic information. In this paper we shall review a number of works, that have been developed based on the framework of the WRP and the VDP.

关键词： Review on theory and applications of wavefront recording plane framework in generation and processing of digital holograms

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Data-embedded-error-diffusion hologram(Invited Paper)

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chinese Optics Letters 2014年第6期12卷 76-79页

作者： P. W. m. tsang t.-c. poon Department of Electronic Engineering City University of Hong KongHong Kong SAR China Bradley Department of Electrical and computer Engineering Virginia TechBlacksburg VA 24061 USA Shanghai Institute of Optics and Fine mechanics Chinese Academy of SciencesShanghai 201800 China

this paper describes a method for converting a complex Fresnel hologram into a phase-only hologram that can be embedded with large amount of data. Briefly, each row of pixels in the hologram is scanned sequentially in a left-to-right direction. the magnitude of each visited pixel is set to a constant, and its phase is embedded with the data. Subsequently, the error is diffused to the neighborhood pixels. the phase hologram realized with such means, which is referred to as the data-embedded-error-diffusion （DEED） hologram, is capable of preserving high fidelity on the content of the hologram and the embedded data.

关键词： Data-embedded-error-diffusion hologram

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Enhancement on the generation of sampled phase-only holograms

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chinese Optics Letters 2015年第6期13卷 27-30页

作者： P.W.m.tsang Y.t.chow t.-c.poon Department of Electronic Engineering City University of Hong Kong Hong KongSpecial Administrative Region (SAR) Bradley Department of Electrical and computer Engineering

Past research has demonstrated that if the intensity image of an object is uniformly down-sampled and converted into a Fresnel hologram, the phase component alone will be sufficient to reconstruct the source image. However, due to down-sampling, the edge and line patterns are degraded heavily. In this Letter, we propose an enhance- ment on the parent method by incorporating an adaptive down-sampling lattice. A hologram generated with our proposed method, which is referred to as the edge-enhanced sampled phase-only hologram, preserves favorable visual quality on both the shaded regions as well as the edge patterns of the object image.

关键词： Lithography Signal sampling

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International validation of the chinese University Prognostic Index for staging of hepatocellular carcinoma: a joint United Kingdom and Hong Kong study

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chinese Journal of cancer 2014年第10期33卷 481-491页

作者： Stephen L.chan Philip J.Johnson Frankie mo Sarah Berhane mabel teng Anthony W.H.chan ming c.poon.paul B.S.Lai Simon Yu Anthony t.c.chan Winnie Yeo State Key Laboratory in Oncology in South china Sir YK Pao Center for CancerDepartment of Clinical OncologyHong Kong Cancer Institute and Prince of Wales HospitalThe Chinese University of Hong Kong School of cancer Sciences University of Birmingham the Department of molecular and clinical cancer medicine Institute of Translational MedicineUniversity of Liverpool Department of Anatomical Cellular and PathologyThe Chinese University of Hong Kong Department of Surgery The Chinese University of Hong Kong Department of Radiology and Organ Imaging The Chinese University of Hong Kong

the outcome of hepatocellular carcinoma(Hcc) patients significantly differs between western and eastern population centers. Our group previously developed and validated the chinese University Prognostic Index(cUPI) for the prognostication of Hcc among the Asian Hcc patient population. In the current study, we aimed to validate the cUPI using an international cohort of patients with Hcc and to compare the cUPI to two widely used staging systems, the Barcelona clinic Liver cancer(BcLc) classification and the cancer of the Liver Italian Program(cLIP). to accomplish this goal, two cohorts of patients were enrolled in the United Kingdom(UK; n = 567; 2006-2011) and Hong Kong(HK; n = 517; 2007-2012). the baseline clinical data were recorded. the performances of the cUPI, BcLc, and cLIP were compared in terms of a concordance index(c-index) and were evaluated in subgroups of patients according to treatment intent. the results revealed that the median follow-up durations of the UK and HK cohorts were 27.9 and 29.8 months, respectively. the median overall survival of the UK and HK cohorts were 22.9 and 8.6 months, respectively. the cUPI stratified the patients in both cohorts into three risk subgroups corresponding to distinct outcomes. the median overall survival of the cUPI low-, intermediate-, and high-risk subgroups were 3.15, 1.24, and 0.29 years, respectively, in the UK cohort and were 2.07, 0.32, and 0.10 years, respectively, in the HK cohort. For the patients who underwent curative treatment, the prognostic performance did not differ between the three staging systems, and all were suboptimal. For those who underwent palliative treatment, the cUPI displayed the highest c-index, indicating that this staging system was the most informative for both cohorts. In conclusion, the cUPI is applicable to both western and eastern Hcc patient populations. the performances of the three staging systems differed according to treatment intent, and the cUPI was demonstrated to be opti

关键词：香港英国预后肝癌验证国际大学中国

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Review of fast methods for point-based computer-generated holography [Invited]

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Photonics Research 2018年第9期6卷 837-846页

作者： P.W.m.tSANG t.-c.poon Y.m.WU Department of Electronic Engineering City University of Hong Kong Bradley Department of Electrical and computer Engineering Virginia Tech

computer-generated holography(cGH) is a technique for converting a three-dimensional(3D) object scene into a two-dimensional(2D), complex-valued hologram. One of the major bottlenecks of cGH is the intensive computation that is involved in the hologram generation process. to overcome this problem, numerous research works have been conducted with the aim of reducing arithmetic operations involved in cGH. In this paper,we shall review a number of fast cGH methods that have been developed in the past decade. these methods,which are commonly referred to as point-based cGH, are applied to compute digital Fresnel holograms for an object space that is represented in a point cloud model. While each method has its own strength and weakness,trading off conflicting issues, such as computation efficiency and memory requirement, they also exhibit potential grounds of synergy. We hope that this paper will bring out the essence of each method and provide some insight on how different methods may crossover into better ones.

关键词：全息术计算机技术发展现状三维技术

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