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The differential genetic signatures related to climatic landscapes for jaguars and pumas on a continental scale

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Integrative Zoology 2021年第1期16卷 2-18页

作者： Marina ZANIN Noa GONZALEZ-BORRAJO Cuauhtémoc CHÁVEZ Yamel rubio Bart HARMSEN Claudia KELLER Pablo VILLALVA Ana Carolina SRBEK-ARAUJO Leonora Pires COSTA Francisco PALOMARES Biology Department Federal University of MaranhãoSão LuísBrazil Departamento de Biologia de la Conservación Estación Biológica de DoñanaSevillaSpain Departamento de Ciencias Ambientales Universidad Autónoma MetropolitanaMexico CityMexico Escuela de Biologia Universidad Autónoma de SinaloaCuliacánMexico Panthera New YorkUSA Biodiversity Coordination Amazon Research InstituteManausBrazil Biology Department Vila Velha UniversityVila VelhaBrazil Biological Sciences Department Federal University of Espírito SantoVitóriaBrazil

Modern and paleoclimate changes may have altered species dynamics by shifting species’niche suitability over space and *** analyze whether the current genetic structure and isolation of the two large American felids,jaguar(Panthera onca)and puma(Puma concolor),are mediated by changes in climatic suitability and connection routes over modern and paleoclimatic *** estimate species distribution under 5 climatic landscapes(modern,Holocene,last maximum glaciations[LMG],average suitability,and climatic instability)and correlate them with individuals’genetic isolation through causal modeling on a resemblance *** species exhibit genetic isolation patterns correlated with LMG climatic suitability,suggesting that these areas may have worked as“allele refuges.”However,the jaguar showed higher vulnerability to climate changes,responding to modern climatic suitability and connection routes,whereas the puma showed a continuous and gradual transition of genetic *** differential responsiveness to climate change,both species are subjected to the climatic effects on genetic configuration,which may make them susceptible to future climatic changes,since these are progressing faster and with higher intensity than changes in the ***,the effects of climatic changes should be considered in the design of conservation strategies to ensure evolutionary and demographic processes mediated by gene flow for both species.

关键词： causal modeling climatic landscape ecological niche modeling gene flow linear mixed model

Hispanic Women＇s Presence in the Actual U.S. Congress

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Journalism and Mass Communication 2015年第11期5卷 593-606页

作者： Antonio Daniel Juan rubio Isabel Maria Gareia Conesa Centro Universitario de la Defensa de San Javier Alicante Spain

The Hispanic population of the United States has become, in recent times, into a powerful electoral force whose vote is historically oriented towards the Democratic Party of the incumbent US President Barack H. Obama. Obviously, this growing electoral strength is reflected into its political presence in the American life that has been accomplished with their numeric inclusion in the US Congress. Although in the recent decades several studies have arisen on the status of the Hispanic community in the United States from both sides of the Atlantic, these have been primarily focused on casuistic, demographic, developmental or educational aspects. But only a few of them, if any, has focused exclusively on the numerical and symbolical representation of the community in the political arena, and more specifically into the main legislative body of the country, the US Congress. And therein it lays the purpose of this article. We intend to investigate not only the historical presence of Hispanic legislators in Congress but also and especially their political influence in the current U.S. Congress. Finally, and prior to the conclusions drawn throughout the paper, we will analyze the political influence of the Hispanic congresswomen in the current 114th Congress. As we will be breaking down, this group has been changing gradually from a poor oppressed minority into one of the most dynamic groups of the country, introduced at all levels of government.

关键词： Hispanic population political presence Hispanic Congresswomen Hispanic political influence

Diabetic nephropathy and inflammation

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World Journal of Diabetes 2014年第3期5卷 393-398页

作者： Montserrat B Duran-Salgado Alberto F rubio-Guerra Clinical Research Unit Hospital General de Ticomán Col Ticomán Mexican Group for Basic and Clinical Research in Internal Medicine Col Ticomán

Diabetic nephropathy(DN) is the leading cause of end-stage renal failure worldwide. Besides, diabetic nephropathy is associated with cardiovascular disease, and increases mortality of diabetic patients. Several factors are involved in the pathophysiology of DN, including metabolic and hemodynamic alterations, oxidative stress, and activation of the renin-angiotensin system. In recent years, new pathways involved in the development and progression of diabetic kidney disease have been elucidated; accumulated data have emphasized the critical role of inflammation in the pathogenesis of diabetic nephropathy. Expression of cell adhesion molecules, growth factors, chemokines and pro-inflammatory cytokines are increased in the renal tissues of diabetic patients, and serum and urinary levels of cytokines and cell adhesion molecules, correlated with albuminuria. In this paper we review the role of inflammation in the development of diabetic nephropathy, discussing some of the major inflammatory cytokines involved in the pathogenesis of diabetic nephropathy, including the role of adipokines, and take part in other mediators of inflammation, as adhesion molecules.

关键词： Diabetic Nephropathy Inflammation Albuminuria Adhesion molecules Cytokines

MMALE—A Methodology for Malware Analysis in Linux Environments

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Computers, Materials & Continua 2021年第5期67卷 1447-1469页

作者： JoséJavier de Vicente Mohino Javier Bermejo Higuera Juan Ramón Bermejo Higuera Juan Antonio Sicilia Montalvo Manuel Sánchez rubio JoséJavier Martínez Herraiz Escuela Superior de Ingeniería y Tecnología Universidad Internacional de La RiojaLogroño26006La RiojaSpain Departamento de Ciencias de la Computación de la Escuela Politécnica Superior Universidad de Alcaláde HenaresAlcaláde HenaresMadridSpain

In a computer environment,an operating system is prone to malware,and even the Linux operating system is not an *** recent years,malware has evolved,and attackers have become more qualified compared to a few years ***,Linux-based systems have become more attractive to cybercriminals because of the increasing use of the Linux operating system in web servers and Internet of Things(IoT)*** is the most employed OS,so most of the research efforts have been focused on its malware protection rather than on other operating *** a result,hundreds of research articles,documents,and methodologies dedicated to malware analysis have been ***,there has not been much literature concerning Linux security and protection from *** address all these new challenges,it is necessary to develop a methodology that can standardize the required steps to perform the malware analysis in depth.A systematic analysis process makes the difference between good and ordinary malware ***,a deep malware comprehension can yield a faster and much more efficient malware *** order to address all mentioned challenges,this article proposed a methodology for malware analysis in the Linux operating system,which is a traditionally overlooked field compared to the other operating *** proposed methodology is tested by a specific Linux malware,and the obtained test results have high effectiveness in malware detection.

关键词： Malware analysis methodology analysis Linux malware IoT malware

Reverse or inverted apical ballooning in a case of refeeding syndrome

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World Journal of Cardiology 2015年第6期7卷 361-366页

作者： Pablo Robles Isabel Monedero Amador rubio Javier Botas Departament of Cardiology Hospital Universitario Fundación Alcorcón

Takotsubo cardiomyopathy is characterized by the development of transient left ventricular regional wall motion abnormalities,in the absence of significant coronary artery obstruction. This syndrome usually occurs in women and is frequently associated with an intense emotional or physical stress. It usually involves apical segments,but in the recent years atypical forms have been described. Inverted or reverse Takotsubo is a variant in which the basal and midventricular segments are hypokinetic,sparing contractile function of the apex. In this report we describe the case of a 54-year-old woman,with chronic malnutrition,initially admitted because of hypoglycemia and severe electrolyte disturbance due to a refeeding syndrome. Within the next hours she experienced acute cardiac symptoms and developed heart failure with low cardiac output. Electrocardiogram(ECG),elevation of troponin and echocardiographic findings were consistent with inverted Takotsubo cardiomyopathy. To the best of our knowledge,this is the first incidence reported of inverted Takotsubo triggered by refeeding syndrome.

关键词： Apical ballooning Refeeding syndrome Anorexia Atrial tachycardia Inverted takotsubo

Response of the Thermal Conductivity as a Function of Water Content of a Burnt Mediterranean Loam Soil

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Open Journal of Soil Science 2012年第1期2卷 1-6页

作者： Carles M. rubio Xavier Ubeda Francesc Ferrer Department Agri-Food Engineering and Biotechnology Polytechnic University of Catalonia Barcelona Spain Department Environmental Biophysics and Soils Lab-Ferrer Soils and Environmental Consulting Cervera Spain Department Physical Geography University of Barcelona Barcelona Spain

The purpose of this research is to explore the variability on the soil thermal conductivity -?- after a prescribe fire, and to assess the effects of the ashes on the heat transfer once it’s were incorporated into the soil matrix. Sampling plot was located in the Montgrí Massif (NE of Spain). A set of 42 soil samples between surface and 5 cm depth was collected before and after the fire. To characterize the soil chemical and physical variables were analyzed. To determine the variability on the soil λ a dry-out curve per scenario (before and after fire) was determined. SoilRho ? method based on ASTM D-5334-08 which was validated by LabFerrer was used. Soil thermal conductivity has shown changes in their values. Indeed, in all moisture scenarios the values of soil λ decreased after soil was burnt. The critical point in the relationshipθ(λ) for the soil after fire which always was stronger than soil before to be burnt. Soil with “white” ashes showed a high thermal conductivity. An X-Ray diffractometry analysis allowed to clarify and to verify these results. To sum up, we could say that thermal conductivity presents changes when the scenario changes, i.e. before and after to be burnt. On the other hand, the volume of ashes incorporated on the soil increased the differences between no burnt and burnt soil, showing even some improvements on the heat transfer when water content started to govern the process.

关键词： Thermal Properties Soil Moisture Prescribed Fire Ashes SoilRHO

Effects of Neonatal Undernutrition on Development of the Dorsolateral Prefrontal Cortex Pyramidal Cells in the Rat

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Journal of Behavioral and Brain Science 2014年第1期4卷 49-57页

作者： Carmen Torrero Mirelta Regalado Lorena.rubio Manuel Salas Department of Developmental Neurobiology and Neurophysiology Institute of Neurobiology National Autonomous University of Mexico Campus UNAM Juriquilla Queretaro Mexico

The dorsolateral prefrontal cortex (dlPFC) of the rat plays a role in the encoding of neuronal signals involved in conflict-induced behavioral adjustment, working memory, planning and executive abilities, attentional control and other cognitive responses. In altricial species, early perinatal undernutrition interferes with the morphofunctional organization of a number of central nervous system (CNS) structures including the prefrontal cortex. The effects of neonatal undernutrition on dendritic arbor density, perikaryon measurements, and the number of spines (detected by rapid-Golgi) of basilar dendritic segments in layer III pyramidal neurons of the dlPFC were examined in male Wistar rats on postnatal (PDs) 12, 20, and 30. In the underfed (U) subjects the distal portions of the dendritic arbors had a consistent hipoplasia, mainly on PD 30, with reduced cross sectional area, perimeter, and spine densities on the basilar dendrites on all days studied. Thus, the alterations of the dlPFC pyramidal neurons may interfere with the plastic synaptic activity and cognitive performance of rats subjected to the stress of early underfeeding. Characterizing these anatomical alterations may help to understand the disrupted cognitive processes associated with neonatal undernutrition.

关键词： Neonatal Undernutrition Prefrontal Cortex Development Stressed Rats

Parabrachial neuron development: Effects of pre- and neonatal undernutrition in the rat

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Open Journal of Molecular and Integrative Physiology 2012年第4期2卷 112-118页

作者： Carmen Torrero Mirelta Regalado Lorena.rubio Manuel Salas Department of Developmental Neurobiology and Neurophysiology Institute of Neurobiology University of Mexico Queretaro Mexico.

Pre-and neonatal fasting in the rat has been used as an experimental model to obtain information on how the newborn gustatory system can be damaged, in- terfering with the basic sensory and hedonic proc- esses to different tastants. Fasting during the prenatal period and for 24 days postnatally results in signifi- cant reductions of body and brain weight, number of branches, dendritic density, and cross-sectional area of the PBN multipolar neurons in the central lateral and central medial subnucleus particularly at post- natal days 20 and 30. Furthermore, the underfeeding paradigm affected more the middle portions of the dendritic tree than other parts of the neurons possibly disturbing the afferent characteristics of neuronal acti- vity propagation that may partly disrupt the elabora- tion of synaptic plasticity at later ages. These findings may play a role in the development of complex physio- logical phenomena such as food intake, taste discrimi- nation, learning taste aversion, and appetitive beha- vior.

关键词： Parabrachial Neurons Development Brainstem Undernutrition Rats

Influence of the Hysteretic Behaviour on Silt Loam Soil Thermal Properties

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Open Journal of Soil Science 2011年第3期1卷 77-85页

作者： Carles M. rubio Ramon Josa Francesc Ferrer 不详

The aim of this research is to explore the influence of hysteresis on heat transport in soils under experimental laboratory conditions. The obtained results shown that, thermal properties as are volumetric specific heat capacity (Cv) and thermal conductivity (θ) showed a positive linear correlation with soil volumetric water content (θ). However, thermal diffusivity values (θ) shown divergences between heat transferred and soil moisture. A spatial-temporal hysteresis pattern was observed on the whole of the thermal properties. This fact was related with factors as: degree of saturation, the influence of temperature difference on the heat transport, and the geometry of the water layer around the particle.

关键词： Water Content Volume Fraction of Air Hysteresis Dual Needle Sensor Heat Pulse