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Lobar lung transplantation from deceased donors: A systematic review

World Journal of Transplantation 2017年第1期7卷 70-80页

作者： michael eberlein Robert M Reed Mayy Chahla Servet Bolukbas Amy Blevins Dirk Van Raemdonck Alessia Stanzi Ilhan Inci Silvana Marasco Norihisa Shigemura Clemens Aigner Tobias Deuse Division of Pulmonary Critical Care and Occupational Medicine University of Iowa Hospitals and Clinics Department of Medicine University of Iowa Hospitals and Clinics University of Iowa Hospitals and Clinics Division of Pulmonary and Critical Care Medicine University of Maryland Department of Thoracic Surgery Helios Klinikum Wuppertal - University Hospital Witten/Herdecke Hardin Library for the Health Sciences University of Iowa Hospitals and Clinics Department of Thoracic Surgery and Lung Transplant Unit University Hospitals Leuven Department of Thoracic Surgery Zurich University Hospital Cardiothoracic Surgery Unit The Alfred Hospital Department of Cardiothoracic Surgery University of Pittsburgh Medical Center Department of Thoracic Surgery Medical University of Vienna Department of Thoracic Surgery and Surgical Endoscopy Ruhrlandklinik University Clinic Essen Tueschener Weg Department of Cardiovascular Surgery University Heart Center Hamburg

AIM To systematically review reports on deceased-donor-lobar lung transplantation(dd LLTx) and uniformly describe sizematching using the donor-to-recipient predicted-total lung-capacity(pT LC) ratio. METHODS We set out to systematically review reports on ddL LTx and uniformly describe size matching using the donorto-recipient pT LC ratio and to summarize reported oneyear survival data of ddL LTx and conventional-LTx. We searched in Pub Med, CINAHL via EBSCO, Cochrane Database of Systematic Reviews via Wiley(CDSR),Database of Abstracts of Reviews of Effects via Wiley(DARE), Cochrane Central Register of Controlled Trials via Wiley(CENTRAL), Scopus(which includes EMBASE abstracts), and Web of Science for original reports on ddL LTx. RESULTS Nine observational cohort studies reporting on 301 ddL LTx met our inclusion criteria for systematic review of size matching, and eight for describing one-year-survival. The dd LLTx-group was often characterized by high acuity;however there was heterogeneity in transplant indications and pre-operative characteristics between studies. Data to calculate the pT LC ratio was available for 242 ddL LTx(80%). The mean pT LCratio before lobar resection was1.25 ± 0.3 and the transplanted pT LCratio after lobar resection was 0.76 ± 0.2. One-year survival in the ddL LTxgroup ranged from 50%-100%, compared to 72%-88%in the conventional-LTx group. In the largest study ddL LTx(n = 138) was associated with a lower one-year-survival compared to conventional-LTx(n = 539)(65.1% vs84.1%, P < 0.001). CONCLUSION Further investigations of optimal donor-to-recipient size matching parameters for ddL LTx could improve outcomes of this important surgical option.

关键词： Lobar lung transplantation from deceased donors Cadaveric lobar lung transplantation Lung size matching Primary graft dysfunction Survival

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Donor to recipient sizing in thoracic organ transplantation

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World Journal of Transplantation 2016年第1期6卷 155-164页

作者： michael eberlein Robert M Reed Division of Pulmonary Critical Care and Occupational Medicine University of Iowa Hospitals and Clinics Division of Pulmonary and Critical Care Medicine University of Maryland

Donor-to-recipient organ size matching is a critical aspect of thoracic transplantation. In the United States potential recipients for lung transplant and heart transplant are listed with limitations on donor height and weight ranges, respectively. Height is used as a surrogate for lung size and weight is used as a surrogate for heart size. While these measures are important predictors of organ size, they are crude surrogates that fail to incorporate the influence of sex on organ size. Independent of other measures, a man's thoracic organs are approximately 20% larger than a woman's. Lung size can be better estimated using the predicted total lung capacity, which is derived from regression equations correcting for height, sex and age. Similarly, heart size can be better estimated using the predicted heart mass, which adjusts for sex, age, height, and weight. These refined organ sizing measures perform better than current sizing practice for the prediction of outcomes after transplantation, and largely explain the outcome differences observed after sex-mismatch transplantation. An undersized allograft is associated with worse outcomes. In this review we examine current data pertaining to size-matching in thoracic transplantation. We advocate for a change in the thoracic allocation mechanism from a height-or-weightbased strategy to a size-matching process that utilizes refined estimates of organ size. We believe that a size-matching approach based on refined estimates of organ size would optimize outcomes in thoracic transplantation without restricting or precluding patients from thoracic transplantation.

关键词： Lung transplant Heart transplant Organ size Size mismatch Organ allocation

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Portfolio theory for squared returns correlated across time

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Probability, Uncertainty and Quantitative Risk 2016年第1期1卷 1-36页

作者： Ernst eberlein Dilip B.Madan University of Freiburg Freiburg im BreisgauGermany University of Maryland College ParkUSA

Allowing for correlated squared returns across two consecutive periods,portfolio theory for two periods is *** correlation makes it necessary to work with non-Gaussian *** two-period conic portfolio problem is formulated and *** development leads to a mean ask price frontier,where the latter employs concave *** modeling permits access to skewness via randomized *** portfolios maximize a conservative market value seen as a bid price for the *** the mean ask price frontier we observe a tradeoff between the deterministic and random drifts and the volatility costs of increasing the deterministic *** a historical perspective,we also implement a mean-variance *** resulting mean-variance frontier is three-dimensional expressing the minimal variance as a function of the targeted levels for the deterministic and random drift.

关键词： frontier theory variance

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德国短途旅客列车转向架

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国外铁道车辆 2000年第6期37卷 24-28页

作者： Tilman eberlein 姚小强

介绍了几种德国地方铁路短途列车用转向架的结构特点、主要参数及生产应用情况。

关键词：短途旅客列车转向架结构特点主要参数

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你是乐观者吗?

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当代外语研究 1997年第6期 3-8页

作者： Tamara eberlein 俞遐岭

汉语习惯讲某人生性乐观,或某人生性悲观。所以,所谓乐观和悲观已非“心理”两字可以涵盖。以前,有一个较为流行的幽默说法:同样半瓶酒,乐观者言,还有半瓶呐!悲观者称,只有半瓶啦!今读此文,深感除此表象外,乐观与悲观有其迥异的思维轨... 详细信息

汉语习惯讲某人生性乐观,或某人生性悲观。所以,所谓乐观和悲观已非“心理”两字可以涵盖。以前,有一个较为流行的幽默说法:同样半瓶酒,乐观者言,还有半瓶呐!悲观者称,只有半瓶啦!今读此文,深感除此表象外,乐观与悲观有其迥异的思维轨迹和心理倾向,读后令人耳目一新!仅举一例,读者不妨作一自测: The pessimist believes bad events stem from permanent conditions("I failed the math quiz because I don’t have a head for numbers") and good events from temporary ones("My husband brought me flowers because he had a good day at work") 对于年轻的父母,以下一句话值得三思: Psychologists believe optimism and pessimism are habits we learn as children. and our parents are our role models. 本文有两处表达灵活运用了英语的构词,竟令汉语“自叹弗如“: a. Hopefulness… requires both willpower and way power—the means to achieve your goals. b. Luckily. learned habits can be unlearned. 句a中的willpower/way power,后者为典型的nonce word(临时造字),新颖别致,与willpower构成头韵(Alliteration);句b中的unlearned也令人叫绝,但是,它不是nonce word。词典对它的释义是:抛掉(?

关键词：蔬菜色拉悲观者自我价值感 requires 心理学家无法管束 failure 免疫系统电动工具自我评价

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加利福尼亚州一年生草场施硫或硫加氮肥增加牛肉产量

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草原与草业 1988年第3期 51-56页

作者： GaleL.Wolters Gary.eberlein 黄友庭

加利福尼亚州一年生草场每隔三年单施硫或硫加氮肥的研究进行了六年。草场施肥效果用牧草生长季节长短,菜牛体重增加,每公顷地放牧菜牛的天数等因素与不施肥草场对照评价。试验表明,施肥处理与不施肥草场比较既不会无限地延长牧草生长季... 详细信息

加利福尼亚州一年生草场每隔三年单施硫或硫加氮肥的研究进行了六年。草场施肥效果用牧草生长季节长短,菜牛体重增加,每公顷地放牧菜牛的天数等因素与不施肥草场对照评价。试验表明,施肥处理与不施肥草场比较既不会无限地延长牧草生长季节,也不会影响菜牛重量增加。在硫加氮处理草场上,放牧天数延长从每公顷地获取的牛肉总产量最高,其次是单施硫草场,不施肥草场最低。单施硫草场与不施肥草场比较,每公顷增产牛肉大约60公斤。硫加氮草场又比单施硫草场增产牛肉接近每公顷50公斤。

关键词：草场施肥处理施硫牛肉产量加利福尼亚州

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恶性高热的新认识和经验

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国际麻醉学与复苏杂志 1987年第5期08卷 298-300页

作者： Schulte-Sasse U eberlein HJ 田玉科

作者对恶性高热(Malignant Hyperthermia; MH)的早期诊断、治疗、预防及应用硝苯呋海因(Dantrolen)在MH治疗中的作用进行了详尽阐明。硝苯呋海因对MH的作用:所有全身麻醉时发生MH的病人,及时静注足量的硝苯呋海因之后,均无后遗症。在采... 详细信息

作者对恶性高热(Malignant Hyperthermia; MH)的早期诊断、治疗、预防及应用硝苯呋海因(Dantrolen)在MH治疗中的作用进行了详尽阐明。硝苯呋海因对MH的作用:所有全身麻醉时发生MH的病人,及时静注足量的硝苯呋海因之后,均无后遗症。在采用硝苯呋海因时代之前而所用的其它药物肯定无效者,不再予以应用。在明确诊断后(或怀疑时),迅速用氧进行有效的通气以适应病人已增高的代谢需要,对硝苯呋海因治疗效应能起决定性作用。经动物实验证明,敏感的猪发生MH时氧耗量明显增加,在进行降温、纠正酸中毒等对症治疗过程中,动物死亡前氧耗量常增加3～4倍。当每分钟通气量不能迅速提高4倍时,则硝苯呋海因能降低过高的代谢状况,而不应影响病人的存活。临床曾

关键词：海因 MH 预防性病人静脉内恶性高热代谢性酸中毒

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UVA1光化学疗法成功治疗成人硬肿病1例

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世界核心医学期刊文摘（皮肤病学分册） 2005年第8期1卷 30-30页

作者： eberlein- Knig B. Vogel M. Katzer K. 崔荣 Klin./Poliklin. Dermatol./Allergol. Technische Universitat Mü nchenBiedersteiner Str.29 80802unchen Mü nchenGermany

Scleredema adultorum is a rare connective tissue disorder of unknown cause. Both bath- PUVA and cream- PUVA therapy were reported to be effective. We describe a patient with scleredema adultorum who showed a striking ... 详细信息

关键词：光化学疗法 UVA1 硬肿结缔组织紊乱中等剂量 cream

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