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Construction and validation of a risk-prediction model for anastomotic leakage after radical gastrectomy: A cohort study in China

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Laparoscopic, Endoscopic and Robotic Surgery 2024年第1期7卷 34-43页

作者： Jinrui Wang Xiaolin Liu Hongying Pan Yihong Xu Mizhi Wu Xiuping Li yang Gao Meijuan Wang mengya yan Nursing Department Sir Run Run Shaw HospitalZhejiang University School of MedicineHangzhou 310016China Department of General Surgery Sir Run Run Shaw HospitalZhejiang University School of MedicineHangzhou 310016China School of Nursing Zhejiang Chinese Medical UniversityHangzhou 310053China

Objectives:Anastomotic leakage(AL)stands out as a prevalent and severe complication following gastric cancer *** frequently precipitates additional serious complications,significantly influencing the overall survival time of *** study aims to enhance the risk-assessment strategy for AL following gastrectomy for gastric ***:This study included a derivation cohort and validation *** derivation cohort included patients who underwent radical gastrectomy at Sir Run Run Shaw Hospital,Zhejiang University School of Medicine,from January 1,2015 to December 31,*** evidence-based predictor questionnaire was crafted through extensive literature review and panel *** on the questionnaire,inpatient data were collected to form a model-derivation *** cohort underwent both univariate and multivariate analyses to identify factors associated with AL events,and a logistic regression model with stepwise regression was developed.A 5-fold cross-validation ensured model *** validation cohort included patients from August 1,2021 to December 31,2021 at the same *** the same imputation method,we organized the validation-queue *** then employed the risk-prediction model constructed in the earlier phase of the study to predict the risk of AL in the subjects included in the validation *** compared the predictions with the actual occurrence,and evaluated the external validation performance of the model using model-evaluation indicators such as the area under the receiver operating characteristic curve(AUROC),Brier score,and calibration ***:The derivation cohort included 1377 patients,and the validation cohort included 131 *** independent predictors of AL after radical gastrectomy included age65 y,preoperative albumin<35 g/L,resection extent,operative time240 min,and intraoperative blood loss90 *** predictive model exhibited a solid AUROC of 0.750(95%CI:0.694e0.806;p<0.001)with a Br

关键词： Stomach neoplasms Anastomotic leak Risk factors Prediction model Risk assessment

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Blastoids generated purely from embryonic stem cells both in mice and humans

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Science China(Life Sciences) 2024年第2期67卷 418-420页

作者： Baojiang Wu yanqiu Wang Jia yan mengya Liu Xihe Li Fuchou Tang Siqin Bao The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock Inner Mongolia UniversityHohhot 010020China Research Center for Animal Genetic Resources of Mongolia Plateau College of Life SciencesInner Mongolia UniversityHohhot 010020China Beijing Advanced Innovation Center for Genomics and Biomedical Pioneering Innovation Center College of Life SciencesPeking UniversityBeijing 100871China Inner Mongolia Saikexing Institute of Breeding and Reproductive Biotechnology in Domestic Animal Hohhot 011517China

Dear Editor,Embryonic stem cells(ESCs)and trophoblast stem cells(TSCs)are derived from blastocysts(Lu et al.,2001).Blastocyst-like structures(blastoids)are self-assembled structures formed by a combination of ESCs and TSCs(Rivron et al.,2018).To increase the success rate of blastoid formation and its similarity with the features of blastocysts,some reports showed that blastoid could also be derived from a combination of three cell lines,ESCs,TSCs,and extraembryonic endoderm cells(XENs),or novel type of stem cells(Sozen et al.,2018;Weatherbee et al.,2023:Wu et al.,2023;Zhang et al.,2023;Zhang et al.,2019).

关键词： purely similarity

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Atmospheric nitrogen deposition affects forest plant and soil system carbon:nitrogen:phosphorus stoichiometric flexibility:A meta-analysis

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Forest Ecosystems 2024年第3期11卷 307-317页

作者： Xiyan Jiang Xiaojing Wang Yaqi Qiao Yi Cao yan Jiao An yang Mengzhou Liu Lei Ma mengya Song Shenglei Fu Key Laboratory of Geospatial Technology for the Middle and Lower Yellow River Regions College of Geography and Environmental ScienceHenan UniversityKaifeng475004China Henan Key Laboratory of Integrated Air Pollution Control and Ecological Security College of Geography and Environmental ScienceHenan UniversityKaifeng475004China Henan Dabieshan National Field Observation and Research Station of Forest Ecosystem Henan UniversityZhengzhou450046China

Background:Nitrogen(N)deposition affects forest stoichiometric flexibility through changing soil nutrient availability to influence plant ***,the effect of N deposition on the flexibility of carbon(C),N,and phosphorus(P)in forest plant-soil-microbe systems remains ***:We conducted a meta-analysis based on 751 pairs of observations to evaluate the responses of plant,soil and microbial biomass C,N and P nutrients and stoichiometry to N addition in different N intensity(050,50–100,>100 kg·ha^(-1)·year^(-1)of N),duration(0–5,>5 year),method(understory,canopy),and matter(ammonium N,nitrate N,organic N,mixed N).Results:N addition significantly increased plant N:P(leaf:14.98%,root:13.29%),plant C:P(leaf:6.8%,root:25.44%),soil N:P(13.94%),soil C:P(10.86%),microbial biomass N:P(23.58%),microbial biomass C:P(12.62%),but reduced plant C:N(leaf:6.49%,root:9.02%).Furthermore,plant C:N:P stoichiometry changed significantly under short-term N inputs,while soil and microorganisms changed drastically under high N *** N addition primarily affected plant C:N:P stoichiometry through altering plant N content,while understory N inputs altered more by influencing soil C and P *** N significantly influenced plant and soil C:N and C:P,while ammonia N changed plant N:*** C:P and soil C:N were strongly correlated with mean annual precipitation(MAT),and the C:N:P stoichiometric flexibility in soil and plant under N addition connected with soil ***,N addition decoupled the correlations between soil microorganisms and the ***:N addition significantly increased the C:P and N:P in soil,plant,and microbial biomass,reducing plant C:N,and aggravated forest P ***,these impacts were contingent on climate types,soil layers,and N input *** findings enhance our comprehension of the plant-soil system nutrient cycling mechanisms in forest ecosystems and plant strategy responses to N deposition.

关键词： C:N:P stoichiometry Meta-analysis Forest ecosystem Nitrogen addition form Nutrient cycles

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Assessing the conservation impact of Chinese indigenous chicken populations between ex-situ and in-situ using genome-wide SNPs

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Journal of Integrative Agriculture 2024年第3期23卷 975-987页

作者： Wenting Li Chaoqun Gao Zhao Cai Sensen yan yanru Lei mengya Wei Guirong Sun Yadong Tian Kejun Wang Xiangtao Kang College of Animal Science and Technology Henan Agricultural UniversityZhengzhou 450002China The Shennong Laboratory Zhengzhou 450002China

Conservation programs require rigorous evaluation to ensure the preservation of genetic diversity and viability of conservation populations. In this study, we conducted a comparative analysis of two indigenous Chinese chicken breeds, Gushi and Xichuan black-bone, using whole-genome SNPs to understand their genetic diversity, track changes over time and population structure. The breeds were divided into five conservation populations(GS1, 2010, ex-situ;GS2, 2019, ex-situ;GS3, 2019, in-situ;XB1, 2010, in-situ;and XB2, 2019, in-situ) based on conservation methods and generations. The genetic diversity indices of three conservation populations of Gushi chicken showed consistent trends, with the GS3 population under in-situ strategy having the highest diversity and GS2 under ex-situ strategy having the lowest. The degree of inbreeding of GS2 was higher than that of GS1 and GS3. Conserved populations of Xichuan black-bone chicken showed no obvious changes in genetic diversity between XB1 and XB2. In terms of population structure, the GS3 population were stratified relative to GS1 and GS2. According to the conservation priority, GS3 had the highest contribution to the total gene and allelic diversity in GS breed, whereas the contribution of XB1 and XB2 were similar. We also observed that the genetic diversity of GS2 was lower than GS3, which were from the same generation but under different conservation programs(in-situ and ex-situ). While XB1 and XB2 had similar levels of genetic diversity. Overall, our findings suggested that the conservation programs performed in ex-situ could slow down the occurrence of inbreeding events, but could not entirely prevent the loss of genetic diversity when the conserved population size was small, while in-situ conservation populations with large population size could maintain a relative high level of genetic diversity.

关键词： genome-wide SNPs conservation genetic diversity ex-situ in-situ

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Preparation,Characterization and Photothermal Study of PVA/Ti_(2)O_(3) Composite Films

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Journal of Wuhan University of Technology(Materials Science) 2024年第3期39卷 658-663页

作者：尚蒙娅 HE yanyan YU Jianhui yan Jiahui XIE Haodi 李金玲 School of Material Science&Engineering Henan University of TechnologyZhengzhou 450001China College of Advanced Interdis-ciplinary Science and Technology Henan University of TechnologyZhengzhou 450001China

In this work,flexible photothermal PVA/Ti_(2)O_(3) composite films with different amount(0 wt%,5 wt%,10 wt%,15 wt%)of Ti_(2)O_(3) particles modified by steric acid were prepared by a simple solution casting *** microstructures,XRD patterns,FTIR spectra,UV-Vis-NIR spectra thermo-conductivity,thermo-stability and photothermal effects of these composite films were all *** results indicated that Ti_(2)O_(3) particles were well dispersed throughout the polyvinyl alcohol(PVA)matrix in the PVA/Ti_(2)O_(3) composite *** Ti_(2)O_(3) particles could also effectively improve the photothermal properties of the composite films which exhibited high light absorption and generated a high temperature(about 57.4℃for film with 15 wt%Ti_(2)O_(3) amount)on the surface when it was irradiated by a simulated sunlight source(1 kW/m^(2)).

关键词： Ti_(2)O_(3)particles solution casting method composite film photothermal conversion

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Towards Data-Driving Multi-View Evaluation Framework for Scratch

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Tsinghua Science and Technology 2024年第2期29卷 517-528页

作者： Xiaolin Chai yan Sun yan Gao Department of Computer Science Beijing University of Posts and TelecommunicationBeijing 100876China Intellectual Property Institute Shandong Polytechnic CollegeJining 272067China

As one of the most popular visual programming languages,Scratch has a lot of evaluation around *** evaluation can help programmers understand their projects *** the same time,it can also provide a reference for them to browse other projects in the online *** of the existing evaluations on Scratch are carried from three perspectives:Computational Thinking(CT)ability,visual presentation aesthetics,and code *** them,the assessment of CT and code quality is mainly carried out from the program script,while the evaluation of visual aesthetics is analyzed from the perspective of image sequences generated by project *** single-view evaluation focuses on the performance of a program in a certain aspect and is *** this paper,we propose a multi-view evaluation framework to integrate various evaluations using different *** quantitatively analyze the assessment of different views driven by *** with overall evaluations that represent human opinions,we analyze their differences and *** experiments,we determine the weights of different integration policies,the proposed multi-view evaluation method can generate evaluation results similar to human opinions.

关键词： Scratch Computational Thinking(CT) visual aesthetic static analysis integration policy machine learning

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Large eddy simulation study of 3D wind field in a complex mountainous area under different boundary conditions

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2024年第7期25卷 541-556页

作者： yan LI Lei yan Xuhui HE School of Civil Engineering Central South UniversityChangsha410075China National Engineering Research Center for High-speed Railway Construction Changsha410075China Hunan Provincial Key Laboratory for Disaster Prevention and Mitigation of Rail Transit Engineering Structures Changsha410075China

Large eddy simulations generally are used to predict 3D wind field characteristics in complex mountainous *** simulation boundary conditions,such as the height and length of the computational domain or the characteristics of inflow turbulence,can significantly impact the quality of *** this study,we examined these boundary conditions within the context of the mountainous terrain around a long-span cable-stayed bridge using a wind tunnel *** sizes of computational domains and turbulent incoming wind velocities were used in large eddy *** results show that when the height of the computational domain is five times greater than the height of the terrain model,there is minimal influence from the top wall on the wind field characteristics in this complex mountainous *** the length of the wake region of the computational domain has negligible effects on the wind *** in the inlet boundary reduces the length of the wake region on a leeward hill with a low slope,but has less impact on the mean wind velocity of steep hills.

关键词： Large eddy simulation(LES) Spectral representation method Recycling method High mountainous canyon Wind characteristics Atmospheric boundary layer Computational domain

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Forward to the Special Topic on“Solving Differential Equations with Deep Learning”

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Journal of Systems Science & Complexity 2024年第2期37卷 389-390页

作者： yan Zhenya Academy of Mathematics and Systems Science Chinese Academy of SciencesBeijing 100190China

The concept of artificial intelligence(AI)was first presented at the Dartmouth SummerResearch Project on AI hosted by McCarthy and Minsky in *** that,the developmentof AI has experienced ups and downs due to some limited conditions including intelligentcomputing techniques,computer and hardware and software^([1,2]).In particular,with the rapidof deep artificial neural networks,machine learning(ML)and deep learning(DL)techniques^([3,4])have been applied in many fields of science and engineering,including machine translation,image recognition,genomics,scientific computing and atmospheric science,etc^([5]).

关键词： has artificial hardware

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Research on Modeling and Parameter Identification of Comprehensive Load Model of Distribution Network in Industrial Park

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Chinese Journal of Electronics 2024年第1期33卷 264-273页

作者： Tingling WANG Xiaohe yan School of Electric Engineering North China University of Water Resources and Electric Power Wenzhou Polytechnic

With the rapid development of industrial parks, its load model research has become a hot spot. In order to study the load of power system in industrial park, based on the characteristics of the industrial park load, a comprehensive load admittance static model with full voltage range adaptability is considered, and a comprehensive load model of distribution network of the industrial park is established. A complete parameter identification of the model is carried out through chaos particle swarm optimization. The simulation results show that the model can effectively describe the load characteristics of the distribution network in industrial parks.

关键词： Chaos Adaptation models Analytical models Parameter estimation Induction motors Simulation Distribution networks

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Electromagnetic characteristic analysis and design of a linear motor used for ultra-high-speed EMS maglev train

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Science China(Technological Sciences) 2024年第6期67卷 1957-1973页

作者： GAO Han SHI TingNa GAO XinMai LEI yanXiao yan Dong GUO Liyan yan yan College of Electrical Engineering Zhejiang UniversityHangzhou310027China Zhejiang University Advanced Electrical Equipment Innovation Center Hangzhou311107China State Key Laboratory of High-speed Maglev Transportation Technology Qingdao266100China CRRC Qingdao Sifang Co.Ltd. Qingdao266111China

The operating speed of the commercial electromagnetic suspension(EMS)maglev train has been over 430 km/h,making it the fastest means of land *** the increasing demands of people traveling,it is necessary to further improve the operating speed of maglev *** to examine whether the existing EMS system can meet the requirements of ultra-highspeed operation(more than 600 km/h),the electromagnetic characteristics of an EMS linear motor under the operating speed of 600–1000 km/h fed by a square-wave voltage supply is investigated in this ***,an electromagnetic field model of the EMS system under the square-wave voltage supply is established to investigate its electromagnetic performance,e.g.,the characteristics of phase current,the magnetic flux density,and the electromagnetic ***,the relationship between the harmonic components of the air-gap magnetic flux density and electromagnetic force is investigated using the two-dimensional fast Fourier transform(2D-FFT)to reveal the mechanism of electromagnetic force ***,to address the issues of excessive armature current density and significant electromagnetic force ripple,the linear motor is re-designed by enlarging the stator slot area and reshaping the mover's main magnetic ***,the Taguchi method is used to further improve the electromagnetic characteristics of the linear electric ***,the effectiveness of the proposed optimal design is validated by the finite-element analysis(FEA)based co-simulation.

关键词： ultra-high-speed maglev transportation electromagnetic suspension(EMS) linear motor electromagnetic force ripple suppression

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