Blastoids generated purely from embryonic stem cells both in mice and humans

作     者：Baojiang Wu Yanqiu Wang Jia Yan Mengya Liu Xihe Li Fuchou Tang Siqin Bao 

作者机构：The State Key Laboratory of Reproductive Regulation and Breeding of Grassland LivestockInner Mongolia UniversityHohhot 010020China Research Center for Animal Genetic Resources of Mongolia PlateauCollege of Life SciencesInner Mongolia UniversityHohhot 010020China Beijing Advanced Innovation Center for Genomics and Biomedical Pioneering Innovation CenterCollege of Life SciencesPeking UniversityBeijing 100871China Inner Mongolia Saikexing Institute of Breeding and Reproductive Biotechnology in Domestic AnimalHohhot 011517China 

出 版 物：《Science China(Life Sciences)》 (中国科学（生命科学英文版）)

年 卷 期：2024年第67卷第2期

页      面：418-420页

核心收录：

学科分类：0710[理学-生物学] 08[工学] 09[农学] 0901[农学-作物学] 0836[工学-生物工程] 090102[农学-作物遗传育种] 

基　　金：supported by the National Natural Science Foundation of China(32060176) the National Key Research and Development Program of China(2022YFD1302202,2022YFD1302203) the Program for Young Talents of Science and Technology in Universities of Inner Mongolia Autonomous Region(NJYT23091) the Program of Higher-Level Talents of Inner Mongolia University(10000-21311201/058) the Inner Mongolia Autonomous Region Natural Science Foundation(2021MS03003) the Inner Mongolia Autonomous Region Science and Technology Plan of China(2020ZD0007,2020ZD0008) the Inner Mongolia Engineering Technology Research Centre of Germplasm Resources Conservation and Utilization(21400-222526) 

主　　题：purely similarity 

摘      要：Dear Editor,Embryonic stem cells(ESCs)and trophoblast stem cells(TSCs)are derived from blastocysts(Lu et al.,2001).Blastocyst-like structures(blastoids)are self-assembled structures formed by a combination of ESCs and TSCs(Rivron et al.,2018).To increase the success rate of blastoid formation and its similarity with the features of blastocysts,some reports showed that blastoid could also be derived from a combination of three cell lines,ESCs,TSCs,and extraembryonic endoderm cells(XENs),or novel type of stem cells(Sozen et al.,2018;Weatherbee et al.,2023:Wu et al.,2023;Zhang et al.,2023;Zhang et al.,2019).