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Coverage analysis of cache-enabled small cell networks with stochastic geometry methods

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The Journal of China Universities of Posts and Telecommunications 2016年第6期23卷 41-46页

作者： Zhang Qi Teng Yinglei liu mengting Song Mei School of Electronic Engineering Beijing University of Posts and Telecommunications

Caching popular content in the storage of small cells is deemed as an efficient way to decrease latency, offload backhaul and satisfy user＇s demands. In order to investigate the performance of cache-enabled small cell networks, coverage probability is studied in both single-point transmission and cooperative multipoint（Co MP） transmission scenarios. Meanwhile, the caching distribution modeled as Zipf and uniform distribution are both considered. Assuming that small base stations（SBSs） are distributed as a homogeneous Poisson point process（HPPP）, the closed-form expressions of coverage probability are derived in different transmission cases. Simulation results show that Co MP transmission achieves a higher coverage probability than that of single-point transmission. Furthermore, Zipf distribution-based caching is more preferable than uniform distribution-based caching in terms of coverage probability.

关键词： caching coverage probability single-point transmission Co MP transmission stochastic geometry

Dissecting the brain with spatially resolved multi-omics

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Journal of Pharmaceutical Analysis 2023年第7期13卷 694-710页

作者： Yijia Fangma mengting liu Jie Liao Zhong Chen Yanrong Zheng Key Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province School of Pharmaceutical SciencesZhejiang Chinese Medical UniversityHangzhou310053China Pharmaceutical Informatics Institute College of Pharmaceutical SciencesZhejiang UniversityHangzhou310058China

Recent studies have highlighted spatially resolved multi-omics technologies,including spatial genomics,transcriptomics,proteomics,and metabolomics,as powerful tools to decipher the spatial heterogeneity of the ***,we focus on two major approaches in spatial transcriptomics(next-generation sequencing-based technologies and image-based technologies),and mass spectrometry imaging technologies used in spatial proteomics and spatial ***,we discuss their applications in neuroscience,including building the brain atlas,uncovering gene expression patterns of neurons for special behaviors,deciphering the molecular basis of neuronal communication,and providing a more comprehensive explanation of the molecular mechanisms underlying central nervous system ***,further efforts are still needed toward the integrative application of multi-omics technologies,including the real-time spatial multi-omics analysis in living cells,the detailed gene profile in a whole-brain view,and the combination of functional verification.

关键词： Central nervous system disorders Multi-omics Spatial transcriptomics Spatial proteomics Spatial metabolomics

Enabling tandem oxidation of benzene to benzenediol over integrated neighboring V-Cu oxides in mesoporous silica

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Chinese Journal of Chemical Engineering 2023年第3期55卷 236-245页

作者： mengting liu Xuexue Dong Zengjing Guo Aihua Yuan Shuying Gao Fu Yang School of Environmental and Chemical Engineering Jiangsu University of Science and TechnologyZhenjiang 212003China School of Chemistry and Chemical Engineering Liaocheng UniversityLiaocheng 252000China State Key Laboratory of Materials-Oriented Chemical Engineering Nanjing Tech UniversityNanjing 210009China

The direct tandem oxidation synthesis of benzenediol from benzene could simplify or even avoid the separation and purification of reaction intermediates, which is promising but challenged because of the further required immediate consecutive activation of intermediate phenol. In this work, a synergistic benzene tandem-oxidation catalyst that V-Cu bimetallic oxides modified nanoporous silica(VCu-NS)was constructed via a facile assembly strategy which involves addictive negative anion citric acid mediating the intercalation of metal-citric acid chelate in mesopore of silica and subsequent thermal calcination inducing dual-metal active site formation. Such a tactic could make amorphous VOxspecies well covered on the surface of mesopore, and ultrafine copper oxide particles surrounded and neighbored by highly dispersed VOxwith strong interplay in mesopore, which was comprehensively confirmed by various characterizations. Benefiting from the unique V-Cu neighboring effect, the desorption of formed phenol over the catalytic site might be restricted therefore easily further activated by the formed reactive oxidative species, 3VCu-NS shows synergetic tandem-oxidation catalytic activities for benzene towards benzenediol with a selectivity of 57%. The result allows optimal 3VCu-NS to be a promising catalyst for benzenediol synthesis from benzene.

关键词： Catalysis Molecular sieve Benzene Synergetic effect Tandem oxidation

Effect of Ginkgo biloba leaf extract on cerebral cortex amino acid levels in cerebral ischemia model rats

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Journal of Traditional Chinese Medicine 2018年第5期38卷 676-684页

作者： Cui Yiran Wu Hongwei liu mengting Qin Haijiao liu Xin Yang Hongjun Beijing Hospital of Traditional Chinese Medicine Capital Medical University Institute of Chinese Materia Medica China Academy of Chinese Medical Sciences College of Science Central South University of Forestry and Technology School of Chinese Materia Medica Beijing University of Chinese Medicine

OBJECTIVE: To investigate the effect of Ginkgo biloba leaf extract on amino acid levels in the cerebral cortex of cerebral ischemia model rats induced by middle cerebral artery occlusion(MCAO).METHODS: A rat model of cerebral ischemia was established by MCAO. Male rats were divided into a negative control group(Control), a sham-operated group(Sham), an ischemic group(MCAO), and an ischemic group treated with Ginkgo biloba leaf extract(MCAO_D). All groups were divided into two subgroups with occlusion times of 12 and 24 h, respectively. The levels of 18 endogenous amino acids in the cerebral cortex were quantified by triple quadrupole-liquid chromatography-mass ***: Compared with the MCAO group, behavioral performance, neurological deficit score, and cerebral infarct volume were significantly improved in the MCAO_D group(P < 0.05, P < 0.01). Compared with the sham group, the levels of 17 amino acids in the cerebral cortex were markedly changed in the MCAO group. The levels of Alanine(Ala), Isoleucine(Ile), Glutamic acid(Glu), Serine(Ser), Valine(Val), Phenylalanine(Phe), Proline(Pro),Threonine(Thr), Lysine(Lys), Tyrosine(Tyr), Hydroxyproline(Hyp), Arginine(Arg), Leucine(Leu),Tryptophan(Trp), and Glycine(Gly) were increased(P < 0.001, P < 0.05), while levels of Gln and Tau were decreased(P < 0.001, P < 0.05). Compared with the MCAO group, Ginkgo biloba extract treatment in the MCAO_D group significantly down-regulated the levels of 11 amino acids, especially those of Arg, Thr, and Ser in 12 or 24 ***: Injection of Ginkgo biloba leaf extract has a therapeutic effect on model rats with MCAO-induced cerebral ischemia by acting on amino acids in the cerebral cortex. This effect might be associated with the regulation of amino acid metabolism in the cerebral cortex.

关键词： Cerebral ischemia Ginkgo biloba leaf extract Amino acids Metabolism

A young patient with Trousseau syndrome presenting with multiple arterial emboli

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World Journal of Emergency Medicine 2024年第5期15卷 428-430页

作者： Linqiang Huang Yin Wen Wenhong Zhong mengting liu Hongke Zeng Department of Critical Care Medicine Guangdong Provincial People’s Hospital(Guangdong Academy of Medical Sciences)Southern Medical UniversityGuangzhou 510080China

Trousseau syndrome is characterized by thromboembolism induced by malignancy[1]and typically affects middle-aged to elderly patients.[2-4]When faced with a young patient suffering from cerebral infarction and diffuse arterial emboli,there is some controversy regarding whether to consider it a concurrent malignancy triggering Trousseau syndrome or to adhere to TOAST(Trial of Org 10172 in Acute Stroke Treatment)for common causes.[5,6]In this case study,we aimed to report a young patient with Trousseau syndrome presenting with multiple arterial emboli.

关键词： arterial patient Acute

Meroterpenoids with Potent Immunosuppressive Activity from Fungus Bipolaris zeicola

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Chinese Journal of Chemistry 2021年第9期39卷 2460-2466页

作者： mengting liu Xueke Zhang Ling Shen Shuang Lin Ying Ye Changxing Qi Jianping Wang Zhengxi Hu Yonghui Zhang Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation School of PharmacyTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei 430030China

Six new meroterpe no ids,bipolarinoids A-F(1-6),and two known congen ers(7-8)were isolated from a soil-derived fungus Bipolaris *** structures were elucidated based on extensive spectroscopic techniques(ineluding HRESIMS and ID and 2D NMR data),and the absolute configurations of 1-4 were further confirmed viasingle-crystal X-ray diffraction an alysis and comparis on of experimental electronic circular dichroism(ECD)***,compound 1 represents the first case of cochlioquinone derivatives featuring a formaldehyde group at C-11, and compou nd 3 features a rareamino group at *** the immunosuppressive activity assay,compounds 5-8 showed potent inhibitory activity against concanavalin A(ConA)-induced T lymphocyte proliferation with IC50 values of 78.3,81.1,48.3,and 48.0 nmol/L,respectively,which provided promising leads for designing and developing new im-muno suppressive agents to treat auto-immunological diseases.

关键词： Bipolaris zeicola Natural products Structure elucidation Immunosuppressive activity Cytotoxicity

Tetrahedral framework nucleic acid carrying angiogenic peptide prevents bisphosphonate-related osteonecrosis of the jaw by promoting angiogenesis

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International Journal of Oral Science 2022年第2期14卷 201-211页

作者： Dan Zhao Dexuan Xiao mengting liu Jiajie Li Shuanglin Peng Qing He Yue Sun Jingang Xiao Yunfeng Lin State Key Laboratory of Oral Diseases&National Clinical Research Center for Oral Diseases&Department of Oral and Maxillofacial Surgery West China Hospital of StomatologySichuan UniversityChengduChina Department of Oral and Maxillofacial Surgery The Affiliated Stomatology Hospital of Southwest Medical UniversityLuzhouChina

The significant clinical feature of bisphosphonate-related osteonecrosis of the jaw(BRONJ)is the exposure of the necrotic *** clinical manifestations include jaw pain,swelling,abscess,and skin fistula,which seriously affect the patients’life,and there is no radical ***,new methods need to be found to prevent the occurrence of ***,a novel nanoparticle,t FNA-KLT,was successfully synthesized by us,in which the nanoparticle tetrahedral framework nucleic acid(tFNA)was used for carrying angiogenic peptide,KLT,and then further enhanced ***-KLT possessed the same characteristics as tFNA,such as simple synthesis,stable structure,and good ***,tFNA enhanced the stability of KLT and carried more KLT to interact with endothelial ***,it was confirmed that tFNA-KLT had the superior angiogenic ability to tFNA and KLT both in vitro and in *** we apply tFNA-KLT to the prevention of *** results showed that tFNA-KLT can effectively prevent the occurrence of BRONJ by accelerating *** summary,the prepared novel nanoparticle,tFNA-KLT,was firstly synthesized by *** was also firstly confirmed by us that tFNA-KLT significantly enhanced angiogenesis and can effectively prevent the occurrence of BRONJ by accelerating angiogenesis,thus providing a new avenue for the prevention of BRONJ and a new choice for therapeutic angiogenesis.

关键词： angiogenesis prevention swelling

Elucidation of the sodium kinetics in layered P-type oxide cathodes

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Science China Chemistry 2022年第10期65卷 2005-2014页

作者： Lianzheng Yu Haojie Dong Yu-Xin Chang Zhiwei Cheng Kang Xu Yi-Hu Feng Duo Si Xu Zhu mengting liu Bing Xiao Peng-Fei Wang Sailong Xu State Key Laboratory of Chemical Resource Engineering Beijing University of Chemical TechnologyBeijing 100029China Center of Nanomaterials for Renewable Energy State Key Laboratory of Electrical Insulation and Power EquipmentSchool of Electrical EngineeringXi’an Jiaotong UniversityXi’an 710049China

Sodium-ion intercalation oxides generally possess high compositional diversity according to their different stacking *** sodium diffusion pathway in layered P-type materials used in sodium-ion batteries is open,which can increase their rate capability by directly transmitting Na+between adjacent triangular prismatic channels,rather than passing through an intermediate tetrahedral site in O-type ***,how the structure chemistry of the P-type oxides determines their electrochemical properties has not been fully understood ***,by comparing the crystalline structures,electrochemical behaviors,ion/electron transport dynamics of a couple of P-type intercalation cathodes,P2-Na_(2/3)Ni1/3Mn_(2/3)O_(2)and P3-Na_(2/3)Ni_(1/3)Mn_(2/3)O_(2)with the same compositions,we demonstrate experimentally and computationally that the P2 phase delivers better cycling stability and rate capability than the P3 counterpart due to the predominant contribution of the faster intrinsic Na diffusion kinetics in the P2 *** also point out that it is the electronic conductivity that captures the key electrochemistry of layered P3-type materials and makes them possible to enhance the sodium storage *** results reveal that the correlation between stacking structure and functional properties in two typical layered P-type cathodes,providing new guidelines for preparing and designing alkali-metal layered oxide materials with improved battery performance.

关键词： sodium-ion batteries cathode P2 phase P3 phase kinetics

Biphase-to-monophase structure evolution of Na_(0.766+x)Li_(x)Ni_(0.33-x)Mn_(0.5)Fe_(0.1)Ti_(0.07)O_(2) toward ultradurable Na-ion batteries

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Carbon Energy 2024年第9期6卷 66-79页

作者： mengting liu Zhiwei Cheng Xu Zhu Haojie Dong Tianran Yan Liang Zhang Lu Zheng Hu-Rong Yao Xian-Zuo Wang Lianzheng Yu Bing Xiao Yao Xiao Peng-Fei Wang State Key Laboratory of Electrical Insulation and Power Equipment School of Electrical EngineeringCenter of Nanomaterials for Renewable EnergyXi'an Jiaotong UniversityXi'anShaanxiChina Jiangsu Key Laboratory of Advanced Negative Carbon Technologies Institute of Functional Nano&Soft Materials(FUNSOM)Soochow UniversitySuzhouJiangsuChina Fujian Provincial Key Laboratory of Quantum Manipulation and New Energy Materials College of Physics and EnergyFujian Normal UniversityFuzhouFujianChina Wenzhou Key Laboratory of Sodium-Ion Batteries Institute for Carbon NeutralizationWenzhou University Technology InnovationWenzhouZhejiangChina

Layered composite oxide materials with O3/P2 biphasic crystallographic structure typically demonstrate a combination of high capacities of the O3 phase and high operation voltages of the P2 ***,their practical applications are seriously obstructed by difficulties in thermodynamic phase regulation,complicated electrochemical phase transition,and unsatisfactory cycling ***,we propose an efficient structural evolution strategy from biphase to monophase of Na_(0.766+x)Li_(x)Ni_(0.33-x)Mn_(0.5)Fe_(0.1)Ti_(0.07)O_(2) through Li+*** role of Li+substitution not only simplifies the unfavorable phase transition by altering the local coordination of transition metal(TM)cations but also stabilizes the cathode–electrolyte interphase to prevent the degradation of TM cations during battery *** a result,the thermodynamically robust O_(3)-Na_(0.826)Li_(0.06)Ni_(0.27)Mn_(0.5)Fe_(0.1)Ti_(0.07)O_(2) cathode delivers a high capacity of 139.4 mAh g^(-1) at 0.1 C and shows prolonged cycling life at high rates,with capacity retention of 81.6%at 5 C over 500 *** work establishes a solid relationship between the thermodynamic structure evolution and electrochemistry of layered cathode materials,contributing to the development of long-life sodium-ion batteries.

关键词： electrochemistry Li+substitution Na-ion batteries O_(3)phase phase transition