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肺部超声评分在婴儿合胞病毒肺炎病情评估中的应用价值

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医学临床研究 2021年第10期38卷 1474-1477页

作者：周梦洁周昱刘金桥李文凤李皓湖南省儿童医院超声科湖南长沙410007 湖南省职业病防治院湖南长沙410007

【目的】探讨肺部超声评分在婴儿呼吸道合胞病毒(Respiratory Syncytial virus,RSV)肺炎病情评估中的应用价值。【方法】回顾性分析2020年3月至2021年5月在湖南省儿童医院诊治的RSV肺炎患儿67例的临床资料,分析肺部超声评分与病情严重... 详细信息

【目的】探讨肺部超声评分在婴儿呼吸道合胞病毒(Respiratory Syncytial virus,RSV)肺炎病情评估中的应用价值。【方法】回顾性分析2020年3月至2021年5月在湖南省儿童医院诊治的RSV肺炎患儿67例的临床资料,分析肺部超声评分与病情严重程度和是否需要呼吸支持的相关性。【结果】RSV患儿病情严重程度与肺部超声评分呈正相关(P<0.05),病情越严重及肺部超声评分越高的患儿,需要呼吸支持的可能性越大。【结论】肺部超声评分可反映RSV肺炎患儿的病情严重程度,可作为一种辅助方法与临床相结合评估肺炎患儿病情严重程度。

关键词：呼吸道合胞病毒肺炎,病毒性/诊断婴儿超声检查

Prediction of damage potential in mainshock–aftershock sequences using machine learning algorithms

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Earthquake Engineering and Engineering Vibration 2024年第4期23卷 919-938页

作者： zhou zhou Wang meng Han Miao yu Xiaohui Lu Dagang School of Civil and Transportation Engineering Beijing University of Civil Engineering and ArchitectureBeijing 100044China Multi-Functional Shaking Tables Laboratory Beijing University of Civil Engineering and ArchitectureBeijing 100044China College of Civil Engineering Tongji UniversityShanghai 200092China College of Civil Engineering and Architecture Guilin University of TechnologyGuilin 541004China School of Civil Engineering Harbin Institute of TechnologyHarbin 150090China

Assessing the potential damage caused by earthquakes is crucial for a community’s emergency *** this study,four machine learning(ML)methods—random forest,extremely randomized trees,AdaBoost(AB),and gradient boosting(GB)—were employed to develop prediction models for the damage potential of the mainshock(DIMS)and mainshock–aftershock sequences(DIMA).Building structures were modeled using eight single-degree-of-freedom(SDOF)systems with different hysteretic rules.A set of 662 recorded mainshock–aftershock(MS-AS)ground motions was selected from the PEER *** intensity measures(IMs)were chosen to represent the characteristics of the mainshock and *** results revealed that the selected ML methods can well predict the structural damage potential of the SDOF systems,except for the AB *** GB model exhibited the best performance,making it the recommended choice for predicting DIMS and DIMA among the four ML ***,the impact of input variables in the prediction was investigated using the shapley additive explanations(SHAP)*** high-correlation variables were sensitive to the structural period(T).At T=1.0 s,the mainshock peak ground velocity(PGVM)and aftershock peak ground displacement(PGDA)significantly influenced the prediction of *** T increased to 5.0 s,the primary high-correlation factor of the mainshock IMs changed from PGVM to the mainshock peak ground displacement(PGDM);however,the highcorrelation variable of the aftershock IMs remained *** high-correlation factors for DIMS showed trends similar to those of ***,a table summarizing the first and second high-correlation variables for predicting DIMS and DIMA were provided,offering a valuable reference for parameter selection in seismic damage prediction for mainshock–aftershock sequences.

关键词： machine learning mainshock-aftershock damage potential prediction the high-correlation variables SDOF systems

Components and Development in Big Data System: A Survey

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Journal of Electronic Science and Technology 2019年第1期17卷 51-72页

作者： Jing-Huan yu Zi-meng zhou the Department of Computer Science City University of Hong Kong

With the growth of distributed computing systems, the modern Big Data analysis platform products often have diversified characteristics. It is hard for users to make decisions when they are in early contact with Big Data platforms. In this paper, we discussed the design principles and research directions of modern Big Data platforms by presenting research in modern Big Data products. We provided a detailed review and comparison of several state-ofthe-art frameworks and concluded into a typical structure with five horizontal and one vertical. According to this structure, this paper presents the components and modern optimization technologies developed for Big Data, which helps to choose the most suitable components and architecture from various Big Data technologies based on requirements.

关键词： Big Data cloud computing data analysis optimization system architecture

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不耦合装药对炸药能量利用率影响的实验研究

爆破 2020年第3期37卷 34-39页

作者：岳中文胡晓冰陈志远魏格平魏正于蒙洲宋家旺中国矿业大学(北京)力学与建筑工程学院北京100083 内蒙古康宁爆破有限责任公司鄂尔多斯017000

通过实验室实验以及数值模拟的方法,对不同不耦合系数装药下炸药在混凝土模型中爆炸所产生的爆破漏斗进行对比分析。得到在相同装药量情况下,不耦合系数分别为1.0、1.4和1.8时,爆破振速的衰减速度随着不耦合系数的增大呈现先减小后增大... 详细信息

通过实验室实验以及数值模拟的方法,对不同不耦合系数装药下炸药在混凝土模型中爆炸所产生的爆破漏斗进行对比分析。得到在相同装药量情况下,不耦合系数分别为1.0、1.4和1.8时,爆破振速的衰减速度随着不耦合系数的增大呈现先减小后增大的趋势,爆破漏斗的体积随着不耦合系数的增大同样呈现先减小后增大的趋势。通过对爆破后粉碎区大小以及炸药爆炸所引起的爆破振动进行比较,发现存在一个最佳不耦合系数使得炸药的能量能够更加充分的利用,提高炸药爆炸时的能量利用率。

关键词：不耦合装药能量利用率爆破振动爆破漏斗数值模拟

Cilostazol,a phosphodiesterase 3 inhibitor,protects mice against acute and late ischemic brain injuries

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Cilostazol,a phosphodiesterase 3 inhibitor,protects mice aga...

A 3-D morphological approach on spatial form and cultural identity of ethnic mountain settlements:Case from Guizhou,China

第十二届全国神经精神药理学学术交流会

作者： Ye Yi-Lu Shi Wen-Zhen Zhang Wei - Ping Wang meng - Ling zhou yu Fang San - Hua Liu Li - Ying Zhang Qi yu yue - Ping Wei Er - Qing Department of Pharmacology, School of Medicine, Zhejiang University, Hangzhou 310058 Department of Pharmacology, Zhejiang Medical College, Hangzhou 310053, China

Cilostazol, a selective inhibitor of phosphodiesterase 3 , exerts neuroprotective effects on acute brain injury after cerebral ischemia in rats. However, it is unknown whether cilostazol affects the subacute or chronic ischemic injury. In the present study, we evaluated the dose - and time - dependent effect of cilostazol on acute ischernic brain injury and the long - lasting effect on the late ( subacute/chronic) injury in mice with focal cerebral ischemia. We found that pre -treatment of cilostazol (injected i. p. at 30 min before ischemia) significantly ameliorated the acute injury 24 h after ischemia, and the effective doses were 3-10 mg/kg. The post - treatment of cilostazol (10 mg/kg) was effective on the

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Journal of Mountain Science 2021年第5期18卷 1144-1158页

作者： JIA Zi-yu meng Cheng-yu zhou Zheng-xu School of Architecture Tsinghua UniversityBeijing 100084China China National Engineering Research Center for Human Settlement China Architecture Design and Research GroupBeijing 100044China School of Landscape Architecture Beijing Forestry UniversityBeijing 100083China

Ethnic mountain settlements are living heritage of varied vernacular *** preservation of both the built form and the intangible socio-cultural associations with them are global concern in process of urbanization,and in the notion of sustainable ***,there is a lack of multi-dimensional and cross-cultural quantitative research in settlement morphology,making it difficult to guide practice ***,this study focuses on exploring an automatic or semi-automatic quantification and classification method for the morphological identity of ethnic mountain *** introduce and combine 3-D morphological indicators with existing 2-D indicators to build and test three different sets of indication systems for semi-automatic classification for the settlements’ethnic attribute basing on spatial *** the Miao,Dong,and Tunpu(Han)ethnic settlements in Guizhou province,southwest China as research samples,we applied factor analysis and hierarchical clustering methods to compare the classification accuracy under the three systems using data from topographic map,field investigation map,satellite imageries,and ethnography or local *** results showed that,the 3-D indication system has succeeded in semi-automatic quantification and classification of settlement morphology and ethnic identity by greatly increasing the classification accuracy to 96.30%,which is a huge improvement compared with the basic 2-D indication system(42.59%)and the advanced 2-D indication system(61.11%).The settlement samples are further divided into two sub-types with significant morphological differences in each major ethnic category under the 3-D indication *** then discussed the potential improvement and future large-scale application of this method with the help of machine learning and other smart *** hope to provide a comprehensive quantitative perspective and a more scientific reference for the future preservation and sustainable

关键词： 3-D morphology Quantitation Ethnic mountain settlements Cultural identity China

miRNA-21-5p is an important contributor to the promotion of injured peripheral nerve regeneration using hypoxia-pretreated bone marrow-derived neural crest cells

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Neural Regeneration Research 2025年第1期20卷 277-290页

作者： meng Cong Jing-Jing Hu Yan yu Xiao-Li Li Xiao-Ting Sun Li-Ting Wang Xia Wu Ling-Jie Zhu Xiao-Jia Yang Qian-Ru He Fei Ding Hai-Yan Shi School of Medicine Nantong UniversityNantongJiangsu ProvinceChina Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education and Coinnovation Center of Neuroregeneration Nantong UniversityNantongJiangsu ProvinceChina Department of Physiology Jiangsu Health Vocational CollegeNanjingJiangsu ProvinceChina Department of Pathology Affiliated Hospital of Nantong UniversityNantongJiangsu ProvinceChina Jiangsu Clinical Medicine Center of Tissue Engineering and Nerve Injury Repair Affiliated Hospital of Nantong UniversityNantongJiangsu ProvinceChina

Our previous study found that rat bone marrow–derived neural crest cells(acting as Schwann cell progenitors)have the potential to promote long-distance nerve ***-based therapy can enhance peripheral nerve repair and regeneration through paracrine bioactive factors and intercellular ***,the complex contributions of various types of soluble cytokines and extracellular vesicle cargos to the secretome remain *** investigate the role of the secretome and extracellular vesicles in repairing damaged peripheral nerves,we collected conditioned culture medium from hypoxia-pretreated neural crest cells,and found that it significantly promoted the repair of sensory neurons damaged by oxygen-glucose *** mRNA expression of trophic factors was highly expressed in hypoxia-pretreated neural crest *** performed RNA sequencing and bioinformatics analysis and found that miR-21-5p was enriched in hypoxia-pretreated extracellular vesicles of neural crest ***,to further clarify the role of hypoxia-pretreated neural crest cell extracellular vesicles rich in miR-21-5p in axonal growth and regeneration of sensory neurons,we used a microfluidic axonal dissociation model of sensory neurons in vitro,and found that hypoxia-pretreated neural crest cell extracellular vesicles promoted axonal growth and regeneration of sensory neurons,which was greatly dependent on loaded ***,we constructed a miR-21-5p-loaded neural conduit to repair the sciatic nerve defect in rats and found that the motor and sensory functions of injured rat hind limb,as well as muscle tissue morphology of the hind limbs,were obviously *** findings suggest that hypoxia-pretreated neural crest extracellular vesicles are natural nanoparticles rich in ***-21-5p is one of the main contributors to promoting nerve regeneration by the neural crest cell *** helps to explain the mechanism of action of the secretome and e

关键词： axotomy cell-free therapy conditioned medium extracellular vesicles hypoxic preconditioning microRNA oxygen-glucose deprivation peripheral nerve injury Schwann cell precursors

Experimental study on dynamic behavior of mechanically pumped two-phase loop with a novel accumulator in simulated space environment

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Chinese Journal of Aeronautics 2022年第12期35卷 102-116页

作者： Qingliang meng Tao ZHANG Feng yu yu ZHAO Zhenming ZHAO Zhenhua zhou Beijing Institute of Space Mechanics and Electricity Beijing 100094China Beijing Key Laboratory of Advanced Optical Remote Sensing Technology Beijing 100094China College of Energy and Mechanical Engineering Shanghai University of Electric PowerShanghai 200090China

Mechanically pumped two-phase loop(MPTL)which is a prominent two-phase heat transfer technology presents a promising prospect in thermal control for space ***,transient behavior of MPTL caused by phase-change and heat sources load-on/off in simulated space environment is rarely *** the present study,one MPTL setup was designed and constructed,and experimentally ***,a novel two-phase thermally-controlled accumulator integrated with passive cooling measure and three capillary structures was designed as the temperature-control *** behavior of the start-up,temperature control,and temperature adjustment were monitored;meanwhile,thermodynamic behavior within the proposed accumulator,the operating behavior as well as the heat and mass transfer behavior between the main loop and the accumulator were *** results show that the fluid management function of the capillary structures for the novel accumulator is *** working point of the MPTL system can be adjusted by changing the temperature control point of the accumulator and it is little influenced by external heat flux and heat sources on/***-drop oscillations which are manifested as fluctuations of temperature and pressure can be observed after phase changing due to the compressible volume within the accumulator and the negative-slope portion of the internal pressure.

关键词： Heat and mass transfer Mechanically pumped twophase loop(MPTL) Pressure drop fluctuation Thermal control Two-phase flow

A cellulose-based lithium-ion battery separator with regulated ionic transport and high thermal stability for extreme environments

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Nano Research 2025年第1期18卷 315-322页

作者： Kun-Peng Yang Song Xie Zi-meng Han Hao-Cheng Liu Chong-Han Yin Wen-Bin Sun Zhang-Chi Ling Huai-Bin Yang De-Han Li Qing-Fang Guan Shu-Hong yu Department of Chemistry New Cornerstone Science LaboratoryInstitute of Biomimetic Materials&ChemistryAnhui Engineering Laboratory of Biomimetic MaterialsDivision of Nanomaterials&ChemistryHefei National Research Center for Physical Sciences at the MicroscaleUniversity of Science and Technology of ChinaHefei 230026China Institute of Innovative Materials Department of Materials Science and EngineeringDepartment of ChemistrySouthern University of Science and TechnologyShenzhen 518055China

Separators play a critical role in lithium-ion ***,the restrictions of thermal stability and inferior electrical performance in commercial polyolefin separators significantly limit their applications under harsh ***,we report a cellulose-assisted self-assembly strategy to construct a cellulose-based separator massively and *** an ultrahigh ionic conductivity in electrolytes of 3.7 mS·cm^(-1) and the ability to regulate ion transport,the obtained separator is a promising alternative for high-performance lithium-ion *** addition,integrated with high thermal stability,the cellulose-based separator endows batteries with high safety at high temperatures,greatly expanding the application scenarios of energy storage devices in extreme environments.

关键词： lithium-ion batteries bio-inspired materials battery separators cellulose nanofiber ultrahigh ionic conductivity high safety