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Status quo and factors of depression and anxiety in patients with non-muscle invasive bladder cancer after plasma electrocision

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World Journal of Psychiatry 2024年第6期14卷 822-828页

作者： Bing Lu meng ding Hong-Bo Xu Chun-Yin Yan Department of Urology Suzhou Dushu Lake HospitalSuzhou 215000Jiangsu ProvinceChina Department of Urology The First Affiliated Hospital of Soochow UniversitySuzhou 215000Jiangsu ProvinceChina

BACKGROUND Bladder cancer is a type of cancer with a high incidence in men.Plasma electrosurgery(PES)is often used in the treatment of bladder cancer.Postoperative complications often cause depression and anxiety in patients after surgery.AIM To investigate the current state of depression and anxiety after PES in patients with non-muscle-invasive bladder cancer and analyze the factors affecting them.METHODS A retrospective study was conducted to compare the baseline data of patients by collecting their medical history and grouping them according to their mental status into negative and normal groups.Logistic regression analysis was used to explore the risk factors affecting the occurrence of anxiety and depression after surgery in patients with bladder cancer.RESULTS Comparative analyses of baseline differences showed that the patients in the negative and normal groups differed in terms of their first surgery,economic status,educational level,and marital status.A logistic regression analysis showed that it affected the occurrence of anxiety in patients with bladder cancer,and the results showed that whether the risk factors were whether or not it was the first surgery,monthly income between 3000 and 3000-6000,secondary or junior high school education level,single,divorced,and widowed statuses.CONCLUSION The risk factors affecting the onset of anxiety and depression in bladder cancer patients after PES are the number of surgeries,economic status,level of education,and marital status.This study provides a reference for the clinical treatment and prognosis of bladder cancer patients in the future.

关键词： Bladder cancer Anxiety Depression Analysis of influencing factors Plasma electrocision

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Stimuli-responsive nanocarriers for bacterial biofilm treatment

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Rare Metals 2022年第2期41卷 482-498页

作者： meng ding Wei Zhao Ling-Jie Song Shi-Fang Luan State Key Laboratory of Polymer Physics and Chemistry Changchun Institute of Applied ChemistryChinese of AcademyChangchun 130022China College of Applied Chemistry and Engineering University of Science and Technology of ChinaHefei 230026China School of Chemistry and Chemical Engineering Yantai UniversityYantai 264005China National Engineering Laboratory of Medical Implantable Devices Key Laboratory for Medical Implantable Devices of Shandong ProvinceWEGO Holding Company LimitedWeihai 264210China

Bacterial biofilm infections have been threatening the human’s life and health globally for a long time because they typically cause chronic and persistent infections.Traditional antibiotic therapies can hardly eradicate biofilms in many cases,as biofilms always form a robust fortress for pathogens inside,inhibiting the penetration of drugs.To address the issues,many novel drug carriers emerged as promising strategies for biofilm treatment.Among them,stimuli-responsive nanocarriers have attracted much attentions for their intriguing physicochemical properties,such as tunable size,shape and surface chemistry,especially smart drug release characteristic.Based on the microenvironmental difference between biofilm infection sites and normal tissue,many stimuli,such as bacterial products accumulating in biofilms(enzymes,glutathione,etc.),lower pH and higher H_(2)O_(2)levels,have been employed and proved in favor of“on-demand”drug release for biofilm elimination.Additionally,external stimuli including light,heat,microwave and magnetic fields are also able to control the drug releasing behavior artificially.In this review,we summarized recent advances in stimuli-responsive nanocarriers for combating biofilm infections,and mainly,focusing on the different stimuli that trigger the drug release.

关键词： Nanocarriers Stimuli responsive Bactericidal Biofilm eradication Drug release

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Chiral multiple-resonance thermally activated delayed fluorescence materials based on chiral spiro-axis skeleton for efficient circularly polarized electroluminescence

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Science China Chemistry 2024年第7期67卷 2257-2264页

作者： Shi-Quan Song Xiao Han Zhong-Zhong Huo Ching-Fai Yip Xian-Fang Hong meng-Ning ding You-Xuan Zheng State Key Laboratory of Coordination Chemistry Jiangsu Key Laboratory of Advanced Organic MaterialsSchool of Chemistry and Chemical EngineeringNanjing UniversityNanjing 210023China Key Laboratory of Mesoscopic Chemistry of Ministry of Education School of Chemistry and Chemical EngineeringNanjing UniversityNanjing 210023China

Chiral luminescence materials have potential applications in the field of three-dimensional displays due to their circularly polarized luminescence(CPL)characteristics.However,the further development of circularly polarized organic light-emitting diodes(CP-OLEDs)needs to meet the requirements of high efficiency,high color purity,low cost,and high dissymmetry factor(gPLor gEL),chiral multiple resonance thermally activated delayed fluorescence(MR-TADF)materials are considered as candidates in these aspects.Herein,based on a pair of chiral spirofluorene precursors,two pairs of high-performance chiral MR-TADF emitters((R/S)-p-Spiro-DtBuCzB and(R/S)-m-Spiro-DtBuCzB)are developed,which exhibit strong emissions peaking at 491 and 502 nm in toluene with full-width at half-maximum values of 25 and 33 nm,respectively.In addition,small singlet–triplet energy gaps of 0.15 and 0.10 eV with high absolute photoluminescence efficiencies of 95.0%and 96.7%are observed for p-Spiro-DtBuCzB and m-Spiro-DtBuCzB molecules,respectively.OLEDs based on p-Spiro-DtBuCzB and m-Spiro-DtBuCzB display high maximum external quantum efficiencies of 29.6%and 33.8%,respectively.Most importantly,CP-OLEDs present symmetric circularly polarized electroluminescence spectra with|gEL|factors of 3.36×10^(-4)and 7.66×10^(-4)for devices based on(R/S)-p-Spiro-DtBuCzB and(R/S)-m-Spiro-DtBuCzB enantiomers,respectively.

关键词： chiral spiro-axis skeleton-based material multiple resonance thermally activated delayed fluorescence circularly polarized electroluminescence dissymmetry factor external quantum efficiency

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Fine Grained Feature Extraction Model of Riot-related Images Based on YOLOv5

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Computer Systems Science & Engineering 2023年第4期45卷 85-97页

作者： Shaofan Su Deyu Yuan Yuanxin Wang meng ding Department of Information Cyber Security People’s Public Security University of ChinaBeijing100038China Key Laboratory of Safety Precautions and Risk Assessment Ministry of Public SecurityBeijing102623China Public Security Behavioral Science Laboratory People’s Public Security University of ChinaBeijing102623China

With the rapid development of Internet technology,the type of information in the Internet is extremely complex,and a large number of riot contents containing bloody,violent and riotous components have appeared.These contents pose a great threat to the network ecology and national security.As a result,the importance of monitoring riotous Internet activity cannot be overstated.Convolutional Neural Network(CNN-based)target detection algorithm has great potential in identifying rioters,so this paper focused on the use of improved backbone and optimization function of You Only Look Once v5(YOLOv5),and further optimization of hyperparameters using genetic algorithm to achieve fine-grained recognition of riot image content.First,the fine-grained features of riot-related images were identified,and then the dataset was constructed by manual annotation.Second,the training and testing work was carried out on the constructed dedicated dataset by supervised deep learning training.The research results have shown that the improved YOLOv5 network significantly improved the fine-grained feature extraction capability of riot-related images compared with the original YOLOv5 network structure,and the mean average precision(mAP)value was improved to 0.6128.Thus,it provided strong support for combating riot-related organizations and maintaining the online ecological environment.

关键词： Convolutional neural network YOLOv5 riot-related fine grained target detection

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Visual inspection of aircraft skin:Automated pixel-level defect detection by instance segmentation

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Chinese Journal of Aeronautics 2022年第10期35卷 254-264页

作者： meng ding Boer WU Juan XU Abdul Nasser KASULE Hongfu ZUO College of Civil Aviation Nanjing University of Aeronautics and AstronauticsNanjing 210016China Key Laboratory of Civil Aircraft Health Monitoring and Intelligent Maintenance of CAAC Nanjing 210016China

Skin defect inspection is one of the most significant tasks in the conventional process of aircraft inspection.This paper proposes a vision-based method of pixel-level defect detection,which is based on the Mask Scoring R-CNN.First,an attention mechanism and a feature fusion module are introduced,to improve feature representation.Second,a new classifier head—consisting of four convolutional layers and a fully connected layer—is proposed,to reduce the influence of information around the area of the defect.Third,to evaluate the proposed method,a dataset of aircraft skin defects was constructed,containing 276 images with a resolution of 960×720 pixels.Experimental results show that the proposed classifier head improves the detection and segmentation accuracy,for aircraft skin defect inspection,more effectively than the attention mechanism and feature fusion module.Compared with the Mask R-CNN and Mask Scoring R-CNN,the proposed method increased the segmentation precision by approximately 21%and 19.59%,respectively.These results demonstrate that the proposed method performs favorably against the other two methods of pixellevel aircraft skin defect detection.

关键词： Aircraft skin Automatic non-destructive testing Defect inspection Instance segmentation Machine vision

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面向机械制造的产品数字化开发技术

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农机使用与维修 2024年第3期 100-102页

作者：丁萌郑州商业技师学院郑州450121

机械制造的产品数字化开发技术是提高机械产品设计效率、促进技术创新的重要技术保障,通过优化设计和生产过程,数字化技术有助于减少材料浪费和能源消耗,从而提高了制造业的可持续性。该文围绕面向机械制造的产品数字化开发技术展开深... 详细信息

机械制造的产品数字化开发技术是提高机械产品设计效率、促进技术创新的重要技术保障,通过优化设计和生产过程,数字化技术有助于减少材料浪费和能源消耗,从而提高了制造业的可持续性。该文围绕面向机械制造的产品数字化开发技术展开深入分析,重点探讨计算机辅助工程(CAE)和数字孪生技术,探讨各项技术在机械制造各个阶段的应用原理与应用特点,并通过具体案例说明其对机械制造的重要性与局限性。研究结果旨在阐明数字化开发技术如何协同作用,促进机械制造领域产品开发的数字化转型,实现更高效、更可持续和更智能的生产方式。

关键词：机械制造数字化技术应用特点协同发展局限

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Static-to-kinematic modeling and experimental validation of tendon-driven quasi continuum manipulators with nonconstant subsegment stiffness

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Chinese Physics B 2024年第1期33卷 316-326页

作者：郑先杰丁萌刘辽雪王璐郭毓 School of Automation Nanjing University of Science and TechnologyNanjing 210094China

Continuum robots with high flexibility and compliance have the capability to operate in confined and cluttered environments. To enhance the load capacity while maintaining robot dexterity, we propose a novel non-constant subsegment stiffness structure for tendon-driven quasi continuum robots(TDQCRs) comprising rigid-flexible coupling subsegments.Aiming at real-time control applications, we present a novel static-to-kinematic modeling approach to gain a comprehensive understanding of the TDQCR model. The analytical subsegment-based kinematics for the multisection manipulator is derived based on screw theory and product of exponentials formula, and the static model considering gravity loading,actuation loading, and robot constitutive laws is established. Additionally, the effect of tension attenuation caused by routing channel friction is considered in the robot statics, resulting in improved model accuracy. The root-mean-square error between the outputs of the static model and the experimental system is less than 1.63% of the arm length(0.5 m). By employing the proposed static model, a mapping of bending angles between the configuration space and the subsegment space is established. Furthermore, motion control experiments are conducted on our TDQCR system, and the results demonstrate the effectiveness of the static-to-kinematic model.

关键词： static-to-kinematic modeling scheme tendon-driven quasi continuum robot nonconstant subsegment stiffness tension attenuation effect

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不确定性的引力:青少年盲盒文化的社会机制研究

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湖北第二师范学院学报 2024年第3期41卷 89-95页

作者：孟凡祺孟丁新西兰奥克兰大学新西兰奥克兰1010 广东外语外贸大学商学院广州510006

盲盒文化是近年在青少年群体中出现的热门现象,青少年通过购买不可视的商品,寻求刺激感、满足感与成就感。运用社会学、人类学中的青少年研究,探索在不确定性主导下的后现代社会中盲盒文化现象的成因、特征和对青少年未来发展的影响。... 详细信息

盲盒文化是近年在青少年群体中出现的热门现象,青少年通过购买不可视的商品,寻求刺激感、满足感与成就感。运用社会学、人类学中的青少年研究,探索在不确定性主导下的后现代社会中盲盒文化现象的成因、特征和对青少年未来发展的影响。通过对广州市三所中学的26名青少年进行了深入的个人访谈与焦点小组讨论,展现了青少年眼中的盲盒文化。青少年通过盲盒消费,不仅创造了独属于“Z世代”的代际文化,建立了群体身份认同,更展现了盲盒文化是中国当代青少年认识风险和不确定性,为未来做积极准备的表现形式。

关键词：青少年文化社会学风险社会

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基于多模型堆叠与特征提取的二打一叫牌算法研究

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重庆理工大学学报（自然科学） 2024年第5期38卷 162-169页

作者：刘航丁濛李淑琴北京信息科技大学计算机学院北京100101 感知与计算智能联合实验室北京100101

针对现有二打一叫牌决策研究中分类粒度低的问题,提出了一种基于多模型堆叠与关键特征提取的叫牌模型训练方案。具体来说,设计了手牌特征构建方法,即由手牌向量、牌型特征、手牌工整度、最小出牌步数以及组合丰富度共同构成玩家手牌特征... 详细信息

针对现有二打一叫牌决策研究中分类粒度低的问题,提出了一种基于多模型堆叠与关键特征提取的叫牌模型训练方案。具体来说,设计了手牌特征构建方法,即由手牌向量、牌型特征、手牌工整度、最小出牌步数以及组合丰富度共同构成玩家手牌特征;在此基础上,提出了使用堆叠法融合4类基模型的决策结果,并训练二层模型CatBoost给出最终决策。实验结果表明:相较于仅使用手牌向量特征,该特征构建方式可显著提升模型性能。经过堆叠法融合多模型决策后,二层模型准确率进一步提升,最终在测试集上达到84.3854%的精准度。所提方法可为其他牌类游戏的叫牌博弈决策提供参考。

关键词：二打一叫牌算法计算机博弈集成学习

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老年甲状腺乳头状癌患者BRAF基因和TERT基因表达及与病理特征和预后的关系

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中国老年学杂志 2024年第3期44卷 541-544页

作者：丁朦燕李予林舟山医院甲状腺外科浙江舟山316000

目的探讨老年甲状腺乳头状癌(PTC)患者B-Raf原癌基因(BRAF)和端粒酶逆转录酶(TERT)基因表达情况及与病理特征和预后的关系。方法选择老年PTC患者81例,采用突变扩增系统PCR法测定BRAF基因突变和TERT基因突变情况。所有患者完成随访1年... 详细信息

目的探讨老年甲状腺乳头状癌(PTC)患者B-Raf原癌基因(BRAF)和端粒酶逆转录酶(TERT)基因表达情况及与病理特征和预后的关系。方法选择老年PTC患者81例,采用突变扩增系统PCR法测定BRAF基因突变和TERT基因突变情况。所有患者完成随访1年,观察患者复发和生存率情况。比较不同病理特征PTC患者BRAF、TERT基因突变情况;比较BRAF基因突变与无BRAF基因突变复发情况、1年生存情况及TERT基因突变与无TERT基因突变复发情况、1年生存情况;采用多因素Logistic回归分析影响老年PTC患者预后危险因素。结果 81例患者BRAF基因突变57例(70.37%),TERT基因突变42例(51.85%)。不同性别、年龄、肿瘤直径、肿瘤数目、脉管侵犯BRAF基因突变率和TERT基因突变率无显著差异(P>0.05);Ⅲ、Ⅳ期BRAF基因突变率和TERT基因突变率显著高于Ⅰ、Ⅱ期(P<0.05);淋巴结转移BRAF基因突变率和TERT基因突变率显著高于无淋巴结转移(P<0.05)。随访1年,复发23例(28.40%);1年生存70例(86.42%)。BRAF基因突变复发率显著高于无BRAF基因突变,1年生存率显著低于无BRAF基因突变(P<0.05)。TERT基因突变复发率显著高于无TERT基因突变,1年生存率显著低于无TERT基因突变(P<0.05)。经多因素Logistic回归分析显示,Ⅲ和Ⅳ期、淋巴结转移、BRAF基因突变和TERT基因突变为影响老年PTC患者预后危险因素。结论老年PTC患者BRAF基因突变和TERT基因突变发生率较高,且与临床分期和淋巴结转移密切相关,为影响老年PTC患者预后危险因素。

关键词：甲状腺乳头状癌 B-Raf原癌基因端粒酶逆转录酶基因病理特征

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