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Hydrocarbon biodegradation and dynamic laser speckle for detecting chemotactic responses at low bacterial concentration

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Journal of Environmental Sciences 2013年第3期25卷 613-625页

作者： melina nisenbaum Gonzalo Hernn Sendra Gastón Alfredo Cerd Gilbert Marcelo Scagliola Jorge Froiln Gonzlez Silvia Elena Murialdo National University of Mar del Plata Faculty of EngineeringDepartment of ChemistryBiochemical Engineering Group.Juan B.Justo 4302(7600)Mar del PlataArgentina National University of Mar del Plata Faculty of EngineeringLaser Laboratory7600Mar del PlataArgentina and Optical Research CenterCONICETLa Plata-CIC.PO Box No.3 1897GonnetLa PlataArgentina OSSE.Obras Sanitarias Mar del Plata-Batn S.E.Quality Management Water Laboratory.French 67377600Mar del PlataArgentina

We report on the biodegradation of pure hydrocarbons and chemotaxis towards these compounds by an isolated chlorophenol degrader,Pseudomonas strain *** biochemical and phylogenetic analysis of the 16S rDNA sequence identified Pseudomonas strain H as having 99.56% similarity with *** *** strain was able to degrade n-hexadecane,1-undecene,1-nonene,1-decene,1-dodecene and *** grew in the presence of 1-octene,while this hydrocarbons is toxic to other hydrocarbons *** strain H was also chemotactic towards n-hexadecane,kerosene,1-undecene and *** results show that this Pseudomonas strain H is an attractive candidate for hydrocarbon-containing wastewater bioremediation in controlled *** the classical standard techniques for detecting chemotaxis are not efficient at low bacterial concentrations,we demonstrate the use of the dynamic speckle laser method,which is simple and inexpensive,to confirm bacterial chemotaxis at low cell concentrations （less than 105 colony-forming unit per millilitre （CFU/mL）） when hydrocarbons are the attractants.

关键词： dynamic laser speckle microorganisms biodegradation chemotaxis hydrocarbons

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Structural and functional analysis of two new positive allosteric modulators of GluR2 desensitization and deactivation

Structural and functional analysis of two new positive allos...

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The 4th ISGO International Conference on Structural Genomics

作者： Autumn M.Weeks David E.Timm Morris J.Benveniste Eric S.nisenbaum Kathryn M.Partin Colorado State University Fort Collins CO80523U.S.A. Lilly Research Labs Lilly Corporate Center IndianapolisIN46285USA Colorado State University Fort Collins CO80523U.S.A. Lilly Research Labs Lilly Corporate Center Indianapolis IN46285 USA Colorado State University Fort Collins CO 80523 U.S.A.

＜正＞Recent crystallographic and functional analyses of AMPA receptors have identified a common binding pocket for two classes of positive allosteric AMPA receptor modulators. From those studies, a working model of channel desensitization and deactivation has been established. Here we present structural and functional data on two new positive allosteric modulators of AMPA receptors. These compounds

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*** effect of eyemasks on reducing stress associated with retinopathy of prematurity screening

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Annals of Eye Science 2018年第1期 438-438页

作者： Andrei-Alexandru Szigiato Matthew Speckert Jeanne Zielonka Kathleen Hollamby Mary Debono Filiberto Altomare Eugene Ng Rosane nisenbaum Michael Sgro Département d'Ophtalmologie Universitéde MontréalMontréalQuébecCanada Department of Ophthalmology and Vision Sciences University of TorontoTorontoOntarioCanada Department of Paediatrics Northern Ontario School of MedicineThunder BayOntarioCanada Department of Neonatology St.Michael’s HospitalTorontoOntarioCanada Faculty of Arts and Sciences University of TorontoTorontoOntarioCanada Department of Neonatology Sunnybrook Health Sciences CentreTorontoOntarioCanada Department of Biostatistics St Michael’s HospitalTorontoOntarioCanada

Background:Retinopathy of prematurity(ROP)is a disorder of retinal development in the low birthweight preterm *** screening is routinely performed for infants at risk of developing this *** these examinations help prevent blindness,they can be physiologically stressful for infants,with changes in oxygen saturation,blood pressure and heart rate occurring during the exam and increased apneic episodes reported the 24-48 hours period *** cause of these increased apneic episodes is not currently *** Background is to evaluate the effect of decreasing light simulation during mydriasis using an eye mask on the frequency of stressful episodes after ROP ***:Multi-centre randomized clinical *** study was approved by hospital ethics boards at all *** informed consent was obtained,infants with a birthweight<1,500 g or gestational age of≤32 weeks and scheduled for their first ROP screening were randomized to receive either standard of care or a phototherapy mask during pupil dilation in addition to routine *** retinal exams were performed by retinal surgeons and *** primary outcome was the frequency of any desaturation,bradycardic event,or apneic event 12 hours following the examination,compared to a baseline rate 12 hours prior to the *** rate,respiratory rate and oxygen saturation were recorded for up to 48 hours following the examination and compared to ***:A total of 51 infants were examined;28 randomized to the masked group and 23 to the control *** and 13 infants were on ventilator support at the time of examination in each group,*** was a 57.7%decrease in the total number of all stressful events in the masked group compared to controls in the 12-hour post exam period(rate ratio 0.42,95%CI,0.2-0.9,P=0.024).There was a 61.3%decrease in the number of bradycardic events in the masked group compared to controls(RR 0.39,95%CI,0.2-1.0,P=0.042).Heart rate was si

关键词： Retinopathy of prematurity(ROP) pain photophobia neonate

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