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Friction 2024年第5期12卷 884-896页

作者： Xingwei WANG Chaoyang ZHANG Chen zhao Yijing LIANG Ming ZHANG Wufang YANG Bo YU Qiangliang YU meirong CAI Feng ZHOU Weimin LIU State Key Laboratory of Solid Lubrication Lanzhou Institute of Chemical PhysicsChinese Academy of SciencesLanzhou730000China Shandong Laboratory of Yantai Advanced Materials and Green Manufacturing Yantai264000China

Developing functional additive resistant to space atomic oxygen(AO)irradiation through simple molecular design and chemical synthesis to enhance the lubricating performance of multialkylated cyclopentanes(MACs)oil is a significant challenge.Herein,sulfur-containing polyhedral oligomere silsesquioxane(POSS)were synthesize via a click-chemistry reaction of octavinyl polyhedral oligomeric with alkyl sulfide.The reduce-friction(RF),anti-wear(AW)properties and anti-AO irradiation of POSS-S-R as MACs base oil additives in atmospheric and simulated space environments were systematically investigated for the first time.Results demonstrate that POSS-S-R not only possesses outstanding anti-AO irradiation capacity but also effectively improves the RF and AW of MACs in atmospheric or simulated space surroundings.This improvement is due to the excellent anti-AO irradiation properties of the POSS structure itself and the high load-carrying ability of silicon-containing and sulfur-containing compounds generated by tribo-chemical reactions,which effectively separates the direct contact of the friction interface.We believe that this synthesized POSS-S-R is a promising additive for space lubricants.

关键词： POSS additive reduce-friction anti-wear multialkylated cyclopentanes(MACs) resistant atomic irradiation

Polyhalogenated carbazoles induce hepatic metabolic disorders in mice via alteration in gut microbiota

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Journal of Environmental Sciences 2023年第5期127卷 603-614页

作者： Chenyang Ji Yunkai Luo Jiawen Yang Yaoyao Dai Jiahui Miao Siqing Yue meirong zhao Key Laboratory of Pollution Exposure and Health Intervention of Zhejiang Province Interdisciplinary Research AcademyZhejiang Shuren UniversityHangzhou 310015China Department of Ultrasound in Medicine The Fourth Affiliated Hospital of Zhejiang University School of MedicalYiwu 322000China Key Laboratory of Microbial Technology for Industrial Pollution Control of Zhejiang Province College of EnvironmentZhejiang University of TechnologyHangzhou 310014China

Polyhalogenated carbazoles(PHCZs)have been widely accepted as emerging pollutants,whereas their ecological and health risks remain uncertain.Herein,female and male Sprague-Dawley(SD)mice were treated with four typical PHCZs to investigate their negative consequences,along with alternations in gutmicrobiota to indicate underlyingmechanisms.In female mice,the relative liver weight ratio increased after four PHCZs exposure;2-bromocarbazole(2-BCZ)increased urine glucose level;3-bromocarbazole(3-BCZ)decreased the glucose and total cholesterol levels;3,6-dichlorocarbazole(3,6-DCCZ)decreased glucose level.The only disturbed biochemical index in male mice was the promoted alkaline phosphatase(ALP)level by 3,6-DCCZ.We also found that the differential blood biochemical indices were correlated with gut microbiota.3-BCZ and 3,6-DCCZ altered Bacteroidetes and Proteobacteria phyla in female and male mice,which were correlated with metabolic disorders.Our findings demonstrated the correlation between PHCZs induced potential hepatotoxicity andmetabolic disordersmay be due to their dioxin-like potentials and endocrine disrupting activities,and the gender differences might result from their estrogenic activities.Overall,data presented here can help to evaluate the ecological and health risks of PHCZs and reveal the underlying mechanisms.

关键词： Polyhalogenated carbazoles Liver Metabolic disorders Gut microbiota

Estrogenic activities of two synthetic pyrethroids and their metabolites

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Journal of Environmental Sciences 2010年第2期22卷 290-296页

作者： Meiqing Jin Ling Li Chao Xu Yuezhong Wen meirong zhao MOE Key Laboratory of Environmental Remediation and Ecosystem Health College of Environmental and Resource Sciences Zhejiang University Hangzhou 310027 China Research Center of Environmental Science College of Biological and Environmental Engineering Zhejiang University of Technology Hangzhou 310032 China

Synthetic pyrethroids （SPs） are among the most common pesticides in current use, and so far, several SPs have been assessed for their potential estrogenicities by various methods. Previous studies have shown that the estrogenicities partly come from their metabolites. Although considerable information is available with respect to the metabolism and environmental degradation of SPs, little is known about the estrogenicities of the metabolites. In this study, permethrin （PM） and β-cypermethrin （CP）, as well as their metabolites （3-phenoxybenzoic alcohol （PBCOH）, 3-phenoxybenzaldehyde （PBCHO） and 3-phenoxybenzoic acid （PBCOOH） were evaluated for their estrogenic activities in the MCF-7 human breast carcinoma cell line. In the MCF-7 cell proliferation assay, PM and CP exhibited significant estrogenic activities at 10-7 mol/L, comparable to 17β-estradiol （E2） of 10-9 tool/L, with the relative proliferative effect ratios of 55.4% and 56.3%, respectively. The real-time quantitative polymerase chain reaction （qRT-PCR） results confirmed the estrogenicities of PM and CP with significant alteration of pS2 and ERα mRNA levels observed at 10-6 mol/L. For the three major metabolites, PBCOH and PBCOOH exhibited estrogenic activities in all assays, while no significant estrogenic responses was observed for PBCHO compared to the vehicle control. In particular, PBCOH had even slightly stronger estrogenic activity than its parent compounds, indicating that metabolism may be one of the reasons for the estrogenicities of the SPs. Given the widespread use of SPs, the toxicological effects of parent compounds and their metabolites should be taken into consideration in the risk assessment of SPs.

关键词： pyrethroids metabolites cell proliferation gene expression estrogenic activity

An optical glass plane angle measuring system with photoelectric autocollimator

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Nanotechnology and Precision Engineering 2019年第2期2卷 71-76页

作者： Yinguo Huang Yong Yang Jiaqi Liang Zhengqing Miao meirong zhao Yelong Zheng State Key Laboratory of Precision Measuring Technology and Instruments Tianjin University

Optical glass is the most widely used optical material.It is necessary to measure its geometric characteristic quickly and reliably to meet the quality of optical glass.A vision measuring system combining photoelectric autocollimation system with high-precision rotary stage is designed to measure the parallelismand angle of optical glass plane.A novel method is proposed to overcome the difficulty ofmeasuring parallelismof optical glass.The model of parallelism and angle measurement is established and the feasibility is analyzed.The image processing algorithm combining Steger algorithm with the least square method is selected.The uncertainty of angle measurement system for angle measurement is 3.0″.The system can solve the problem of measuring the angle of optical glass with high precision and has important significance for optical system.

关键词： Optical glass Plane angle Parallelism Photoelectric autocollimation system

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1株拮抗禾谷镰刀菌生防菌株的筛选鉴定

江苏农业科学 2024年第11期52卷 128-133页

作者：赵美荣李永春张志超赤峰学院化学与生命科学学院内蒙古赤峰024000

为有效预防由禾谷镰刀菌引起的作物病害,提供生物防治新资源,筛选并鉴定可以有效抑制禾谷镰刀菌的生防菌。采用稀释平板法从小麦生境中分离菌株,以禾谷镰刀菌为指示菌,利用平板对峙法筛选生防菌株,通过形态学观察、菌株生理生化检测以及... 详细信息

为有效预防由禾谷镰刀菌引起的作物病害,提供生物防治新资源,筛选并鉴定可以有效抑制禾谷镰刀菌的生防菌。采用稀释平板法从小麦生境中分离菌株,以禾谷镰刀菌为指示菌,利用平板对峙法筛选生防菌株,通过形态学观察、菌株生理生化检测以及16S rDNA、gyrB基因序列分析对生防菌株进行鉴定,并检验其对5种植物病原真菌的抑菌效果,测定其抑菌范围。筛选出1株对禾谷镰刀菌具有明显抑菌作用的菌株B2-211022-01,抑菌率为57.95%,其菌落形态、生理生化特征与芽孢杆菌相一致,通过序列同源性分析发现,该菌株的16S rDNA、gyrB基因序列与贝莱斯芽孢杆菌(Bacillus velezensis)同源性最高,分别为99.9%、100.0%,系统进化树构建结果显示,菌株B2-211022-01与贝莱斯芽孢杆菌属于一个分支,鉴定该菌株为贝莱斯芽孢杆菌,该菌株除了能抑制禾谷镰刀菌外,还对冬瓜枯萎病病菌、芍药灰霉病病菌、番茄灰霉病病菌、牡丹炭疽病病菌、黄瓜枯萎病病菌等5种供试植物病原真菌表现出一定的抑制作用,抑菌范围较广,在农业生产中具有一定的病害防治潜力。

关键词：禾谷镰刀菌生物防治贝莱斯芽孢杆菌抑菌作用生防菌株

基于自适应条件直方图均衡的红外图像细节增强算法

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红外技术 2024年第1期46卷 52-60页

作者：马群赵美蓉郑叶龙孙琳倪锋天津大学精密仪器与光电子工程学院天津300072 天津津航技术物理研究所天津300308

红外图像普遍存在对比度低、细节不清晰、边缘特征不突出等问题。针对这些问题,本文提出了一种自适应条件直方图均衡的红外图像细节增强算法。采用引导滤波将红外图像分解为背景层和细节层;然后采用自适应阈值邻域条件直方图结合对比度... 详细信息

红外图像普遍存在对比度低、细节不清晰、边缘特征不突出等问题。针对这些问题,本文提出了一种自适应条件直方图均衡的红外图像细节增强算法。采用引导滤波将红外图像分解为背景层和细节层;然后采用自适应阈值邻域条件直方图结合对比度受限直方图均衡方式,对背景层图像进行灰度压缩和对比度增强;接着利用引导滤波的中间计算结果构造滤噪掩模,在对细节层进行增强的同时有效滤除背景噪声;最后将背景层和细节层处理结果进行线性融合得到细节增强后红外图像。主观评价和客观数据计算表明,本文提出的红外图像细节增强算法无须手动调节参数即可实现对各类场景的自适应,可以在抑制噪声的前提下,有效增强图像细节,并提升图像整体对比度水平。对算法进行了嵌入式移植,显示效果和资源占用表明算法具有很强的工程化应用水平。

关键词：红外图像增强引导滤波直方图均衡嵌入式移植

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基于游戏化的移动端交互设计教学研究与实践

玩具世界 2024年第1期 242-244页

作者：孙美荣赵国栋贺州学院湖南科技学院

基于游戏化的移动端交互设计研究，重在思想，强调设计。在课程实践和交互设计探索过程中，注重夯实专业设计的基础，积极引导学生注重用户需求，以用户体验为中心，将游戏化手段移植到移动端交互设计中来，创作出具有游戏化体验的移动... 详细信息

基于游戏化的移动端交互设计研究，重在思想，强调设计。在课程实践和交互设计探索过程中，注重夯实专业设计的基础，积极引导学生注重用户需求，以用户体验为中心，将游戏化手段移植到移动端交互设计中来，创作出具有游戏化体验的移动端产品，增强交互的参与感和趣味性，以此提升用户粘性。通过优化交互设计课程体系，拓展学生的综合创新能力，提高专业化核心素养。

关键词：游戏化移动端交互设计教学实践

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基于等效最小光程的大范围浊度测量方法

光学技术 2024年第3期50卷 339-345页

作者：张海韬王宏远甄理郑叶龙赵美蓉黄银国天津大学精密测试技术与仪器国家重点实验室天津300072

浊度测量在水质监测等领域有重要应用。针对大范围浊度测量问题,提出了一种基于等效最小光程的浊度测量方法。利用90°散射法,通过多组光程与散射光强测量值进行线性拟合,计算出光强截距,建立了光强截距与待测浊度的数学关系。该光强截... 详细信息

浊度测量在水质监测等领域有重要应用。针对大范围浊度测量问题,提出了一种基于等效最小光程的浊度测量方法。利用90°散射法,通过多组光程与散射光强测量值进行线性拟合,计算出光强截距,建立了光强截距与待测浊度的数学关系。该光强截距表征最小光程条件下的等效散射光强,从而减小了高浊度下光程的影响,保证了低浊度和高浊度区间的高测量精度。搭建了13路光程组合的浊度测量实验装置,实验结果表明,在250~2000 NTU的范围内,该方法最大相对误差为2.818%,与散射法直接测量相比,平均相对误差降低约71%,在保证测量精度的前提下扩展了散射法的测量范围。

关键词：浊度测量散射法最小光程光强截距

农业强国背景下面向农村的职业教育改革与发展:时代使命、现实困境与逻辑框架

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南宁师范大学学报（哲学社会科学版） 2024年第2期45卷 69-83页

作者：赵美荣杨俏丽陈春潮广西农业职业技术大学食品药品工程学院广西南宁530007 广西社会科学界联合会东南亚经济与政治研究院广西南宁530022 广西民族大学民族学与社会学学院广西南宁530006 梧州学院大数据与软件工程学院广西梧州543000

面向农村的职业教育与农业强国建设具有密切的内在关联。农业强国建设在增强粮食和重要农产品安全稳定供给保障,强化农业农村现代化科技装备支撑、智力支持和人才支撑,提高农业产业链供应链韧性和稳定性等方面,赋予了面向农村的职业教... 详细信息

面向农村的职业教育与农业强国建设具有密切的内在关联。农业强国建设在增强粮食和重要农产品安全稳定供给保障,强化农业农村现代化科技装备支撑、智力支持和人才支撑,提高农业产业链供应链韧性和稳定性等方面,赋予了面向农村的职业教育更高的改革与发展定位和时代使命。然而,面向农村的职业教育仍存在体系不健全、人才培养模式创新不够和人才培养效果有待提高、师资队伍水平不高和激励机制不完善、专业设置与农业农村现代化融合发展衔接不够强等现实困境。因此,在锚定建设农业强国的目标中,面向农村的职业教育须发挥更大作用和实现更大作为,其工作重点是:建立多层次贯通衔接且深度开放的面向农村的职业教育体系,创新涉农职业院校产教融合协同模式和人才培养模式,加强师资队伍建设,并以强国需求为目标,改革涉农职业院校知识体系和专业设置。

关键词：农业强国面向农村的职业教育乡村振兴农业农村现代化

八珍汤加减结合口服营养制剂治疗气血亏虚型晚期胃癌的疗效及对营养状态、精神状态的影响分析

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中医临床研究 2024年第6期16卷 93-95页

作者：赵美蓉张梦娜逄艳青岛市黄岛区第二中医医院山东青岛266400

目的:在气血亏虚型晚期胃癌疾病患者临床治疗过程采取八珍汤加减结合口服营养制剂疗法,研究观察此种中西医联合治疗方式的临床效果及对患者营养状况、精神状态两个方面所带来的影响。方法:随机选取医院1年多时间内(2020年1月―2021年2月... 详细信息

目的:在气血亏虚型晚期胃癌疾病患者临床治疗过程采取八珍汤加减结合口服营养制剂疗法,研究观察此种中西医联合治疗方式的临床效果及对患者营养状况、精神状态两个方面所带来的影响。方法:随机选取医院1年多时间内(2020年1月―2021年2月)所治疗的气血亏虚型晚期胃癌患者(样本观察数量为86例),采用随机数字表法将其分为两组,即对照组与观察组,其中对照组使用口服营养制剂治疗,观察组在此基础上加用八珍汤加减治疗,比较两组临床疗效、治疗前后营养状态[其中主要涉及白蛋白(Albumin,Alb)、前白蛋白(Prealbumn,PA)、血清总蛋白(Total Protein,TP)这3项指标水平]与精神状态[使用焦虑自评量表(Self-rating Anxiety Scale,SAS)、抑郁自评量表(Self-rating Depression Scale,SDS)进行评估]的变化情况。结果:治疗2周后,与对照组比较,观察组疗效更高(P0.05),治疗2周后,与对照组比较,观察组Alb、PA、TP等指标水平更高,SAS评分、SDS评分更低(P <0.05)。结论:对气血亏虚型晚期胃癌患者使用八珍汤加减结合口服营养制剂治疗效果较好,可有效改善营养状态与精神状态,具有较高的临床推广价值。

关键词：气血亏虚证晚期胃癌八珍汤营养制剂疗效