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Laparoscopic hepatectomy using indocyanine green attenuates postoperative inflammatory response for hepatocellular carcinoma:A propensity score matching analysis

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World Journal of Gastrointestinal Surgery 2025年第1期17卷 193-202页

作者： Wei-Xun wu Ming-Bin Huang mei-xia Wang Li-Hua Chen Bo Hu Zhen-Bin Ding Department of Liver Surgery Zhongshan Hospital(Xiamen)Fudan UniversityXiamen 361006Fujian ProvinceChina Department of Infection Management Zhongshan Hospital(Xiamen)Fudan UniversityXiamen 361015Fujian ProvinceChina Department of Liver Surgery and Transplantation Liver Cancer InstituteZhongshan HospitalFudan UniversityShanghai 200032China Key Laboratory of Carcinogenesis and Cancer Invasion(Ministry of Education) Fudan UniversityShanghai 200032China

BACKGROUND Improving the intraoperative and postoperative performance of laparoscopic hepatectomy was quite a challenge for liver *** To determine the benefits of indocyanine green(ICG)fluorescence imaging in patients with hepatocellular carcinoma(HCC)who underwent laparoscopic hepatectomy during and after *** We retrospectively collected the clinicopathological data of 107 patients who successfully underwent laparoscopic hepatectomy at Zhongshan Hospital(xiamen),Fudan University from June 2022 to June *** using the ICG fluorescence imaging technique,we divided them into the ICG and non-ICG *** eliminate statistical bias,a 1:1 propensity score matching analysis was *** comparison of perioperative outcomes,including inflammationrelated markers and progression-free survival,was analyzed *** Intraoperatively,the ICG group exhibited lower blood loss,a shorter surgical time,lower hepatic inflow occlusion(HIO)frequency,and a shorter total HIO ***,the participation of ICG resulted in a shorter duration of hospitalization(6.5 vs 7.6 days,P=0.03)and postoperative inflammatory response attenuation(lower neutrophil-lymphocyte ratio on the first day after surgery and platelet-lymphocyte ratio on the third day,P<0.05).Although the differences were not significant,the levels of all inflammation-related markers were lower in the ICG *** rates of postoperative complications and the survival analyses,including progression-free and overall survivals showed no significant difference between the *** The involvement of ICG fluorescence imaging may lead to improved perioperative outcomes,especially postoperative inflammatory response attenuation,and ultimately improve HCC patients’recovery after surgery.

关键词： Hepatocellular carcinoma Laparoscopic hepatectomy Indocyanine green fluorescence Postoperative inflammatory response attenuation Propensity score matching analysis

Efficacy and Safety of Zihua Wenfei Zhisou Granule in Treatment of Postinfectious Cough: A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase Ⅱ Clinical Trial

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Chinese Journal of Integrative Medicine 2025年第1期31卷 3-10页

作者： LI Ting LIU Xue-mei YANG mei wu Yan-qing LIU Wei MAO Bing JIANG Hong-li Division of Pulmonary Medicine Department of Internal MedicineInstitute of Integrated Traditional Chinese and Western MedicineWest China HospitalSichuan UniversityChengdu610041China Department of Pulmonary Diseases State Key Laboratory of Biotherapy of ChinaWest China HospitalSichuan UniversityChengdu610041China

Objective: To evaluate the efficacy and safety of Chinese medicine(CM) Zihua Wenfei Zhisou Granule(ZWZG) in postinfectious cough(PIC) patients with CM syndrome of wind-cold invading Fei(Lung,WCIF). Methods: This is a multicenter, randomized, double-blind, parallel-group, placebo-controlled phase Ⅱclinical trial. PIC patients with WCIF syndrome were recruited from the Respiratory Departments in 6 hospitals across China between March 2019 and December 2020. Eligible patients were randomly assigned to group A(ZWZG-matched placebo 15 g), group B(active ZWZG 15 g), and group C(active ZWZG 10 g plus ZWZGmatched placebo 5 g) in a 1:1:1 ratio. All medications were taken orally 3 times daily for 14 consecutive days. The primary outcomes were cough relief rate and cough disappearance rate. The secondary outcomes included time to cough relief, time to cough disappearance, and changes in cough symptom score(CSS), cough Visual Analog Scale(VAS) value, Cough-Specific Quality of Life Questionnaire(CQLQ) score, and CM syndrome score from baseline(day 0) to post-treatment(day 14). Adverse events(AEs) in each group were recorded. Results: A total of 198 patients were included in the full analysis set(FAS) and safety analysis set(SS), while 183 were enrolled in the per-protocol analysis set(PPS). In the FAS population, the cough relief rate was 47.76%, 90.77% and 84.85%in groups A, B, and C, respectively;while the cough disappearance rate was 31.34%, 72.31% and 68.18%,respectively. The cough relief rates and cough disappearance rates in groups B and C were significantly higher than group A(P<0.0001). Both the median time to cough relief and cough disappearance in groups B and C were shorter than group A(P<0.0001). Compared with group A, groups B and C showed significantly greater improvements from baseline to post-treatment in CSS during daytime and nighttime as well as VAS(P<0.05).There were no significant differences in changes from baseline to post-treatment in CQLQ and CM syndrome

关键词： postinfectious cough Zihua Wenfei Zhisou Granule randomized controlled trial Chinese medicine

Dynamic compressive characteristics of a green sandstone under coupled hydraulic-mechanical loading: Experiments and theoretical modeling

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Journal of Rock Mechanics and Geotechnical Engineering 2025年第1期17卷 126-138页

作者： Bangbiao wu Geli Zhao Ying Xu Kaiwen xia State Key Laboratory of Hydraulic Engineering Intelligent Construction and Operation School of Civil EngineeringTianjin UniversityTianjin300072China Yalong River Hydropower Development Company Ltd.Chengdu610065China Institute of Geosafety China University of Geosciences(Beijing)Beijing100083China

Deep rock is under a complex geological environment with high geo-stress, high pore pressure, and strong dynamic disturbance. Understanding the dynamic response of rocks under coupled hydraulic-mechanical loading is thus essential in evaluating the stability and safety of subterranean engineering structures. Nevertheless, the constraints in experimental techniques have led to limited prior investigations into the dynamic compression behavior of rocks subjected to simultaneous high in-situ stress and pore pressure conditions. This study utilizes a triaxial split Hopkinson pressure bar (SHPB) system in conjunction with a pore pressure loading cell to conduct dynamic experiments on rocks subjected to hydraulic-mechanical loading. A porous green sandstone (GS) was adopted as the testing rock material. The findings reveal that the dynamic behavior of rock specimens is significantly influenced by multiple factors, including the loading rate, confining stress, and pore pressure. Specifically, the dynamic compressive strength of GS exhibits an increase with higher loading rates and greater confining pressures, while it decreases with elevated pore pressure. Moreover, the classical Ashby-Sammis micromechanical model was augmented to account for dynamic loading and pore pressure considerations. By deducing the connection between crack length and damage evolution, the resulting law of crack expansion rate is related to the strain rate. In addition, the influence of hydraulic factors on the stress intensity factor at the crack tip is introduced. Thereby, a dynamic constitutive model for deep rocks under coupled hydraulic-mechanical loading was established and then validated against the experimental results. Subsequently, the characteristics of introduced parameter for quantifying the water-induced effects were carefully discussed.

关键词： Deep rock Split hopkinson pressure bar(SHPB) Compressive behavior Pore pressure Coupled hydraulic-mechanical loading

Achieving further refinement of grain structure and improvement of mechanical properties in Al-12Si-4Cu-2Ni-1Mg alloy by Al-Ti-C-B master alloy addition and deep cryogenic treatment

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China Foundry 2025年第1期22卷 75-82页

作者： Lin-fei xia Wen-bo Li Zuo-shan Wei Yu-ying wu xiang-fa Liu China Key Laboratory for Liquid-Solid Structural Evolution and Processing of Materials Ministry of EducationShandong UniversityJinan 250061China Shandong Key Laboratory of Advanced Aluminum Materials and Technology Binzhou Institute of TechnologyBinzhou 256600ShandongChina

Near-eutectic Al-Si alloys are widely used in automotive manufacturing due to their superior wear resistance and high temperature *** of high Si content,the grain refinement of near-eutectic Al-Si alloy has been a problem for many *** this study,the effect of deep cryogenic treatment(DCT)on the microstructure and mechanical properties of Al-12Si-4Cu-2Ni-Mg alloy with addition of Al-Ti-C-B master alloy was fully *** show that the average grain size of the alloy is greatly reduced from 0.92 mm to 0.50 mm,and the eutectic Si and Al7Cu4Ni precipitates are spheroidized and refined in Al-12Si-4Cu-2Ni-Mg after DCT for 24 h and aging *** these changes of microstructures result in a significant increment of about 22.5%in elongation and a slight enhancement of about 6.8%in tensile ***,the refinement of microstructure also significantly improves the fatigue life of the alloy.

关键词： deep cryogenic treatment near-eutectic Al-Si master alloy microstructure mechanical properties

High Efficiency Mixed Amine Adsorbents for Directly Capturing Carbon Dioxide from Air

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Chemical Research in Chinese Universities 2025年第1期41卷 138-145页

作者： wu Yilu ZHENG Haolong xia Zihan FU Chengmin XU Feng YAN Jian School of Environment and Chemical Engineering Foshan UniversityFoshan528000P.R.China Guangzhou Zhixin High School Guangzhou510080P.R.China

The development of effective adsorbents with high amine efficiency and CO_(2)adsorption almost unaffected by humidity is extremely *** this study,we introduce an innovative solid amine adsorbent,TETA/DEA@FS,composed of triethylenetetramine(TETA)and diethanolamine(DEA)functionalized fumed silica(FS),which exhibits exceptional capability in selectively capturing trace CO_(2)from N_(2).TETA/DEA@FS shows an exceptionally high capacity of CO_(2)adsorption of 1.13 mmol/g at the temperature of 298 K and the pressure of 0.0004 bar(1 bar=100 kPa),and achieves an unprecedented CO_(2)/N_(2)IAST selectivity of 1.70×10^(12).TETA/DEA@FS exhibits high amine efficiency,with breakthrough experiments demonstrating that CO_(2)adsorption remains nearly unaffected by ***,TETA/DEA@FS demonstrates rapid CO_(2)adsorption kinetics and outstanding cyclic stability.

关键词： Direct air capture(DAC) CO_(2) N_(2) Triethylenetetramine Diethanolamine

Giant low-field magnetocaloric effect in unstable antiferromagnetic Tm1-xErxNi2Si2（x=0.2,0.4） compounds

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Journal of Rare Earths 2025年第2期43卷 312-318页

作者： Bo Xu Lu Tian Junfeng Wang mei wu Xinqiang Gao Zhenxing Li Jun Shen School of Rare Earths University of Science and Technology of China Key Laboratory of Rare Earths Ganjiang Innovation AcademyChinese Academy of Sciences Department of Energy and Power Engineering School of Mechanical EngineeringBeijing Institute of Technology

Magnetic refrigeration（MR） technology is regarded as an ideal solution for cryogenic applications,relying on magnetocaloric materials which provide necessary chilling effect.A series of polycrystalline Tm1-xErxNi2Si2（x=0.2,0.4） compounds was synthesized,and their magnetic properties,magnetic phase transition together with magnetocaloric effect（MCE） were *** Tm1-xErxNi2Si2（x=0.2,0.4）compounds display a field-induced metamagnetic transition from antiferromagnetic（AFM） to ferromagnetism（FM） in excess of 0.2 T,***,the AFM ground state is *** the field change of 0-2 T,the values of maximal magnetic entropy change(-ΔSMmax) and refrigerant capacity（RC） for Tm0.8Er0.2Ni2Si2compound are 17.9 J/（kg·K） and 83.5 J/kg,*** large reversible MCE under low magnetic fields（≤2 T） indicates that Tm0.8Er0.2Ni2Si2compound can serve as potential candidate materials for cryogenic magnetic refrigeration.

关键词： Cryogenic magnetic refrigeration Magnetocaloric effects Magnetocaloric materials Rare earths TmNi2Si2

Enteromorpha prolifera polysaccharide-Fe(Ⅲ) complex promotes intestinal development as a new iron supplement

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Science China(Life Sciences) 2025年第1期68卷 219-231页

作者： Yingying Feng Yuying wu Jialu Wang Zhenglin Dong Qian Yu Shuangshuang xia Chunxue Liu Haihua Wang Xin wu Tianjin Institute of Industrial Biotechnology Chinese Academy of SciencesTianjin 300308China CAS Key Laboratory of Agro-ecological Processes in Subtropical Region Institute of Subtropical AgricultureChinese Academy of SciencesChangsha 410125China ANYOU Biotechnology Group Co.Ltd Taicang 215412China Qingdao Seawin Biotech Group Co. LTDQingdao 266071China

Iron is a crucial micronutrient, and its deficiency can have detrimental effects on the health of infants. Dietary polysaccharide-iron(Ⅲ) complexes(PICs) are promising for addressing iron deficiency due to their minimal adverse reactions and high iron absorption rate. This study aimed to investigate the effects of dietary Enteromorpha prolifera polysaccharide-Fe(Ⅲ) complex(EP-Fe) on newborns, using 3-day weaned piglets as the iron-deficiency model. Results showed that EP-Fe improved iron levels and promoted intestinal development in piglets. Transcriptome sequencing revealed that EP-Fe increased the survival of intestinal epithelial cells under hypoxia by upregulating the expression of genes that promote the development of the vascular system. Additionally, EP-Fe enhanced the mucosal barrier functions by inhibiting myosin light chain kinase(MLCK)/phosphorylated myosin light chain(p-MLC) signaling pathway to increase the expression of intestinal tight junction proteins. Furthermore, the 16S r RNA gene sequencing of gut microbiota showed that EP-Fe promoted the enrichment of Bacteroides_fragilis and other gut microbes that can metabolize carbohydrates. In conclusion, EP-Fe is an effective iron supplement for newborns, and it can be developed as a comprehensive nutritional supplement.

关键词： Enteromorpha prolifera polysaccharide-Fe(III)complex iron deficiency intestinal development gut microbiota weaned piglet

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高校联盟与地方应用型高校建设内在关系分析

湖南师范大学教育科学学报 2015年第6期14卷 126-128页

作者：夏美武徐月红铜陵学院安徽铜陵244000

应用型高校的产生及发展源于经济社会发展需要,它追求的是教育与经济社会相适应、人才培养与生产劳动相结合、科研开发与利用的一体化。组建校政、校企、校校、校所等"五位一体"高校战略联盟是应用型高校健康发展的根本保障,也是应用型... 详细信息

应用型高校的产生及发展源于经济社会发展需要,它追求的是教育与经济社会相适应、人才培养与生产劳动相结合、科研开发与利用的一体化。组建校政、校企、校校、校所等"五位一体"高校战略联盟是应用型高校健康发展的根本保障,也是应用型人才培养的内在必然要求。联盟是应用型高校与社会有机对接、互动共生、共建共荣的耦合场,要实现校社共建、共生、共荣、共赢的联盟目的,必须妥善解决好联盟建立的动机、机制和文化等问题。

关键词：应用型高校战略联盟内在联系高教改革

Paving the Way towards Green Development:Impact of the Belt and Road Initiative on Electrification in Participating Countries

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China & World Economy 2025年第1期33卷 36-63页

作者： Mao Zhou Jiahui wu xia Wang Chang Liu School of International Business Southwestern University of Finance and Economics(SWUFE)China School of International Business SWUFEChina School of Public Finance and Taxation SWUFEChina Institute of Western China Economic Research SWUFEChina

Electrification is crucial for achieving global net zero emissions and reducing energy poverty, particularly in developing countries involved in the Belt and Road Initiative (BRI). This study uses the difference-in-differences method to examine the BRI's impact on electrification levels in 118 countries from 2009 to 2020. Its findings indicate that the BRI increased electrification in BRI countries by approximately 1 percent compared with non-BRI countries. This increase was driven primarily by enhanced trade and investments, which facilitated imports of power equipment and supported China-backed power-plant projects. The BRI's impact was more pronounced in Maritime Silk Road countries, high-income nations, and those with favorable business environments. Although the BRI promoted both renewable and nonrenewable power equipment imports, it primarily favored nonrenewable infrastructure investments. Given China's expertise in clean energy, there remains untapped potential for the BRI to prioritize renewable energy integration, fostering a sustainable and low-carbon future.

关键词： Belt and Road Initiative electrification level power equipment import.power plant investment