检索结果-南通市图书馆

Geodynamics of oceanic plateau and plume head accretion and their role in Phanerozoic orogenic systems of China

Geoscience Frontiers 2015年第1期6卷 49-59页

作者： Peter G.Betts Louis Moresi meghan s.miller David Willis school of Earth Atmosphere and EnvironmentMonash UniversityClayton Campus school of Mathematical sciences Monash UniversityClayton Campus Department of Earth sciences University of Melbourne Department of Earth sciences University of Southern California

We present three 3D numerical models of deep subduction where buoyant material from an oceanic plateau and a plume interact with the overriding plate to assess the influence on subduction dynamics, trench geometry, and mechanisms for plateau accretion and continental growth. Transient instabilities of the convergent margin are produced, resulting in： contorted trench geometry; trench migration parallel with the plate margin; folding of the subducting slab and orocline development at the convergent margin; and transfer of the plateau to the overriding plate. The presence of plume material beneath the oceanic plateau causes fiat subduction above the plume, resulting in a ＂bowed＂ shaped subducting slab. In plateau-only models, plateau accretion at the edge of the overriding plate results in trench migration around the edge of the plateau before subduction is re-established directly behind the trailing edge of the plateau. The plateau shortens and some plateau material subducts. The presence of buoyant plume material beneath the oceanic plateau has a profound influence on the behaviour of the convergent margin. In the plateau ~ plume model, plateau accretion causes rapid trench advance. Plate convergence is accommodated by shearing at the base of the plateau and shortening in the overriding plate. The trench migrates around the edge of the plateau and subduction is re-established well behind the trailing edge of the plateau, effectively embedding the plateau into the overriding plate. A slab window forms beneath the accreted plateau and plume material is transferred from the subducting plate to the over- riding plate through the window. In all of the models, the subduction zone maintains a relatively stable configuration away from the buoyancy anomalies within the downgoing plate. The models provide a dynamic context for plateau and plume accretion in Phanerozoic accretionary orogenic systems such as the East China Orogen and the Central Asian Orogen （Altiads）, which ar

关键词： subduction Accretion Plateau Plume Central Asian Orogen Geodynamics

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

阿拉斯加下地幔D”层结构

阿拉斯加下地幔D”层结构

引用

2014年中国地球科学联合学术年会——专题7：核幔边界和地核的结构及动力学

作者：孙道远 Don Helmberger meghan s.miller 中国科学技术大学地球和空间科学学院 California Institute of Technology Seismological LaboratoryUSA University of southern California Department of Earth SciencesUSA

D"层作为地幔最底部的一层,是地球内部重要的热学、化学和相变边界层。全球地震层析成像结果表明在环太平洋下方的核幔边界上普遍分布了高速异常体,通常认为这些高速体和到达核幔边界的俯冲板块相关。这些冷的板块和钙钛矿到后钙钛矿相...

D"层作为地幔最底部的一层,是地球内部重要的热学、化学和相变边界层。全球地震层析成像结果表明在环太平洋下方的核幔边界上普遍分布了高速异常体,通常认为这些高速体和到达核幔边界的俯冲板块相关。这些冷的板块和钙钛矿到后钙钛矿相变进一步相互作用,在板块边缘产生强烈的D"不连续界面的起伏。因此研究D"层精细结构及与俯冲板块的关系对探讨地球深内部条件下的矿物特性以及地幔对流特性都有重要促进作用。大部分地震学上对D"的观测来源于对下地幔s波

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Model Change Active Learning in Graph-Based semi-supervised Learning

引用

Communications on Applied Mathematics and Computation 2024年第2期6卷 1270-1298页

作者： Kevin s.miller Andrea L.Bertozzi Department of Mathematics University of CaliforniaLos Angeles520 Portola PlazaLos AngelesCA 90095USA

Active learning in semi-supervised classification involves introducing additional labels for unlabelled data to improve the accuracy of the underlying classifier.A challenge is to identify which points to label to best improve performance while limiting the number of new labels."Model Change"active learning quantifies the resulting change incurred in the classifier by introducing the additional label(s).We pair this idea with graph-based semi-supervised learning(ssL)methods,that use the spectrum of the graph Laplacian matrix,which can be truncated to avoid prohibitively large computational and storage *** consider a family of convex loss functions for which the acquisition function can be efficiently approximated using the Laplace approximation of the posterior *** show a variety of multiclass examples that illustrate improved performance over prior state-of-art.

关键词： Active learning Graph-based methods semi-supervised learning(ssL) Graph Laplacian

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Review of research methodologies for tigers:Telemetry

引用

Integrative Zoology 2010年第4期5卷 378-389页

作者： Clayton s.miller Mark HEBBLEWHITE John M.GOODRICH Dale G.MIQUELLE Wildlife Conservation society BronxNYUSA Wildlife Biology Program College of Forestry and ConservationUniversity of MontanaMissoulaMontanaUSA

Over the past half century,wildlife research has relied on technological advances to gain additional insight into the secretive lives of *** revolution started in the 1960s with the development of radio telemetry and continues today with the use of Global Positioning system(GPs)-based research *** the present paper we review the history of radio telemetry from its origins with grizzly bears in Yellowstone to its early applications in tiger research and conservation in *** address the different types of data that are available using radio telemetry as opposed to using other research techniques,such as behavioral observations,camera trapping,DNA analysis and scat *** the late 1990s,the rapid development of GPs collar technology revolutionized wildlife *** new technology has enabled researchers to dramatically improve their ability to gather data on animal movements and *** the ecological and conservation benefits of radio telemetry,there have been few telemetry studies of tigers in the wild,and most have been on the Bengal or Amur *** close with an assessment of the current tiger conservation efforts using GPs technology and discuss how this new information can help to preserve tigers for future generations.

关键词： Global Positioning system technology Panthera tigris radio telemetry research methodologies tiger

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Mortality of Amur tigers:The more things change,the more they stay the same

引用

Integrative Zoology 2015年第4期10卷 344-353页

作者： Hugh s.ROBINsON John M.GOODRICH Dale G.MIQUELLE Clayton s.miller Ivan V.sERYODKIN Panthera New YorkNew YorkUSA Wildlife Conservation society BronxNew YorkUSA Wildlife Biology Program College of Forestry and ConservationUniversity of MontanaMissoulaMontanaUSA Pacific Geographical Institute Far Eastern Branch of the Russian Academy of SciencesVladivostokRussia Far Eastern Federal University VladivostokRussia

Poaching as well as loss of habitat and prey are identified as causes of tiger population *** some studies have examined habitat requirements and prey availability,few studies have quantified cause-specific mortality of *** used cumulative incidence functions(CIFs)to quantify cause-specific mortality rates of tigers,expanding and refining earlier studies to assess the potential impact of a newly emerging *** quantify changes in tiger mortality over time,we re-examined data first collected by Goodrich et al.(2008;study period 1:1992–2004)as well as new telemetry data collected since January 2005(study period 2:2005–2012)using a total of 57 tigers(27 males and 30 females)monitored for an average of 747 days(range 26–4718 days).Across the entire study period(1992 to 2012)we found an estimated average annual survival rate of 0.75 for all tigers *** was the primary cause of mortality during both study periods,followed by suspected poaching,distemper and natural/unknown *** 2005,poaching mortality has remained relatively constant and,if combined with suspected poaching,may account for a loss of 17–19%of the population each *** distemper virus(CDV)may be an additive form of mortality to the population,currently accounting for an additional 5%.Despite this relatively new source of mortality,poaching remains the main threat to Amur tiger survival and,therefore,population growth.

关键词： canine distemper virus cause-specific mortality cumulative incidence function Panthera tigris altaica poaching

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Revisiting cerebral endothelial cells in Alzheimer’s disease

引用

Neural Regeneration Research 2025年第10期20卷 2911-2912页

作者： Amira s.Hanafy Department of Neurosurgery University Hospital BonnBonnGermany

Alzheimer’s disease(AD)is the most common neurodegenerative disorder characterized by slow and progressive decline of cognitive and memory *** only approximately 5%of the cases,AD is familial,as often predisposed by genetic mutations(Hoogmartens et al.,2021),while sporadic AD accounts for approximately 95%of the *** amyloid cascade hypothesis is one of the fundamental hypotheses put out to explain AD pathogenesis as dysregulated homeostasis of amyloid-β(Aβ)peptides that leads to the accumulation of Aβplaques in the parenchyma,an anatomical hallmark of AD.

关键词： Alzheimer Aβ cerebral

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Emerging structures and dynamic mechanisms ofγ-secretase for Alzheimer’s disease

引用

Neural Regeneration Research 2025年第1期20卷 174-180页

作者： Yinglong Miao Michael s.Wolfe Computational Medicine Program and Department of Pharmacology University of North Carolina–Chapel HillChapel HillNCUSA Department of Medicinal Chemistry University of KansasLawrenceKSUSA

γ-secretase,called“the proteasome of the membrane,”is a membrane-embedded protease complex that cleaves 150+peptide substrates with central roles in biology and medicine,including amyloid precursor protein and the Notch family of cell-surface *** inγ-secretase and amyloid precursor protein lead to early-onset familial Alzheimer’s disease.γ-secretase has thus served as a critical drug target for treating familial Alzheimer’s disease and the more common late-onset Alzheimer’s disease as ***,critical gaps remain in understanding the mechanisms of processive proteolysis of substrates,the effects of familial Alzheimer’s disease mutations,and allosteric modulation of substrate cleavage byγ-*** this review,we focus on recent studies of structural dynamic mechanisms ofγ-*** mechanisms,including the“Fit-stay-Trim,”“sliding-Unwinding,”and“Tilting-Unwinding,”have been proposed for substrate proteolysis of amyloid precursor protein byγ-secretase based on all-atom molecular dynamics *** an incorrect registry of the Notch1 substrate was identified in the cryo-electron microscopy structure of Notch1-boundγ-secretase,molecular dynamics simulations on a resolved model of Notch1-boundγ-secretase that was reconstructed using the amyloid precursor protein-boundγ-secretase as a template successfully capturedγ-secretase activation for proper cleavages of both wildtype and mutant Notch,being consistent with biochemical experimental *** approach could be potentially applied to decipher the processing mechanisms of various substrates byγ-*** addition,controversy over the effects of familial Alzheimer’s disease mutations,particularly the issue of whether they stabilize or destabilizeγ-secretase-substrate complexes,is ***,an outlook is provided for future studies ofγ-secretase,including pathways of substrate binding and product release,effects of modulators on familial Alzheimer’s disease mutations

关键词： Alzheimer’s disease amyloid precursor protein cryo-EM structures drug design intramembrane proteolysis molecular dynamics Notch

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Complementary roles of glial cells in generating region-specific neuroinflammatory responses and phagocytosis in Parkinson’s disease

引用

Neural Regeneration Research 2025年第10期20卷 2917-2918页

作者： Leyre Ayerra Maria s.Aymerich Universidad de Navarra Facultad de CienciasDepartamento de Bioquímica y GenéticaPamplonaSpain CIMA-Universidad de Navarra PamplonaSpain IdisNA Instituto de Investigación Sanitaria de NavarraPamplonaSpain

Neuroinflammation is associated with Parkinson’s disease:Reactive gliosis and neuroinflammation are hallmarks of Parkinson’s disease(PD),a multisystem neurodegenerative disorder characterized by a progressive loss of dopaminergic *** has long been considered a mere consequence of neuronal loss,but whether it promotes PD or is a key player in disease progression remains to be *** leukocyte antigen.

关键词： inflammation leukocyte generating

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

structure and magnetostructural correlation of ferrimagnetic meso-tetraphenylporphinatoman- ganese（III） dimethyl-N,N＇-dicyanoquinone diiminide, [MnTPP]~[Me2DCNQI]＂-

引用

中国科学：化学 2012年第6期42卷 907-910页

作者： L.Arthur Jordan H.Lapidus saul W.stephens Peter s.miller Joel Department of Chemistry University of Utah salt Lake City Utah 84112-0850 UsA Department of Physics Photon sciences Directorate Brookhaven National Laboratory Upton NY 11973 UsA

The structure [MnⅢTPP][Me2DCNQI] (TPP = tetraphenylporphinato; Me2DCNQI = 2,5-dimethyl-N,N′- dicyanoquinone-diimine) has been determined from X-ray powder diffraction data. The nonsolvated structure is composed of linear (1-D) chains of alternating [MnⅢTPP]+and μ-[Me2DCNQI]·- with intrachain Mn···Mn separations of 12.83 Å, and a Mn-NDCNQIdistance of 2.18 Å. The dihedral angle between the mean Mn(N4)TPPand [Me2DCNQI]·-planes, and the Mn-(N-C)DCNQIangle are 84.18° and 143.6°, respectively. [MnⅢTPP][Me2DCNQI] has a Tcof 4.3 K from the 10 Hz c"(T) data, 2-K coercivity of 5,600 Oe, and 6,300 emuOe/mol remnant magnetization that are reduced from that observed for related materials, and their inclusion extends the magnetostructural correlation between the intrachain coupling and both the dihedral angle between the mean Mn(N4)TPPand [TCNE]·-(TCNE = tetracyanoethylene) planes and Mn-(N-C)TCNEangles. This is in accord with the intrachain coupling arising from the overlap of the MnⅢdz2-like singly occupied molecular orbital (sOMO) and the z component of the [TCNE]·-π*(πz*) sOMO, which increases with decreasing dihedral angle between the mean Mn(N4)TPPand [TCNE]·-planes and Mn-(N-C)TCNEangle.

关键词：结构组成二甲基亚铁磁性四苯基卟啉细观粉末衍射数据 TPP 二面角

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Determining the mechanism behind yoga’s effects on preventing the symptoms of Alzheimer’s disease

引用

Neural Regeneration Research 2020年第2期15卷 261-262页

作者： Adithy Hassan meghan Robinson stephanie M. Willerth Division of Medical sciences 3800 Finnerty RoadUniversity of VictoriaVictoriaBritish ColumbiaCanada The Vancouver Prostate Centre VancouverBritish ColumbiaCanada Department of Mechanical Engineering University of VictoriaVictoriaBritish ColumbiaCanadaCentre for Biomedical ResearchUniversity of VictoriaVictoriaBritish ColumbiaCanadaInternational Collaboration on Repair DiscoveriesUniversity of British ColumbiaVancouverBritish ColumbiaCanada

Background on the relationship between meditation/yoga practice and its effect on Alzheimer's disease (AD): Dementia refers to a variety of conditions that affect the normal function of the brain, leading to symptoms like memory loss, issues with problem solving, difficulty in processing thoughts and disordered language (McKhann et al., 2011).

关键词： effects yoga Alzheimer's disease

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：