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Tea tree oil,a vibrant source of neuroprotection via neuroinflammation inhibition:a critical insight into repurposing Melaleuca alternifolia by unfolding its characteristics

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2023年第7期24卷 554-573页

作者： md Atiar rahman Abida SULTANA Mohammad Forhad KHAN Rachasak BOONHOK Sharmin AFROZ Department of Biochemistry and Molecular Biology University of ChittagongChittagong-4331Bangladesh School of Allied Health Sciences Walailak UniversityNakhon Si Thammarat 80160Thailand Department of Chemistry University of Massachusetts BostonBostonMA 02125USA Department of Medical Technology School of Allied Health Sciencesand Research Excellence Center for Innovation and Health Products(RECIHP)Walailak UniversityNakhon Si Thammarat 80160Thailand Department of Theoretical and Computational Chemistry University of DhakaDhaka-1000Bangladesh

Over the past few decades,complementary and alternative treatments have become increasingly popular *** purported therapeutic characteristics of natural products have come under increased scrutiny both in vitro and in vivo as part of efforts to legitimize their *** such product is tea tree oil(TTO),a volatile essential oil primarily obtained from the native Australian plant,Melaleuca alternifolia,which has diverse traditional and industrial applications such as topical preparations for the treatment of skin *** anti-inflammatory-linked immunomodulatory actions have also been *** systematic review focuses on the anti-inflammatory effects of TTO and its main components that have shown strong immunomodulatory *** extensive literature search was performed electronically for data curation on worldwide accepted scientific databases,such as Web of Science,Google Scholar,PubMed,ScienceDirect,Scopus,and esteemed publishers such as Elsevier,Springer,Frontiers,and Taylor&*** that the majority of pharmacological studies were conducted on crude oils only,the extracted data were critically analyzed to gain further insight into the prospects of TTO being used as a neuroprotective agent by drug formulation or dietary *** addition,the active constituents contributing to the activity of TTO have not been well justified,and the core mechanisms need to be unveiled especially for anti-inflammatory and immunomodulatory effects leading to ***,this review attempts to correlate the anti-inflammatory and immunomodulatory activity of TTO with its neuroprotective mechanisms.

关键词： Tea tree oil Anti-inflammatory Anti-viral Antibacterial Terpinen-4-ol18-Cineole Neuroprotective effect

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Left-turn phasing selection considering vehicle to vehicle and vehicle to pedestrian conflicts

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Journal of Traffic and Transportation Engineering(English Edition) 2023年第1期10卷 58-69页

作者： Kakan C.Dey md Tawhidur rahman Subasish Das Amrit Manova Williams Wadsworth Department of Civil and Environmental Engineering West Virginia UniversityMorgantownWV 26506USA AECOM Technical Services Inc.PhoenixAZ 85020USA Ingram School of Engineering Texas State UniversitySan MarcosTX 78666USA Davenport Engineering CharlotteNC 28273USA

Left-turning vehicle movement at signalized intersections with permissive left-turn phases creates safety concerns due to the higher chance of conflict with opposing-through vehicles and *** this research,a simulation-based study was conducted to evaluate pedestrians’impact on traffic conflicts between left-turning vehicles and opposing-through vehicles(V-V conflicts)as well as traffic conflicts between left-turning vehicles and pedestrians(V-P conflicts)in the permissive left-turn phasing *** with different opposing-through volumes,left-turn volumes,number of opposing-through lanes,and pedestrian volumes were modeled in VISSIM,a traffic *** surrogate safety assessment model(SSAM)was used to estimate the number of V-V and VP *** effect of pedestrian presence on V-V and V-P conflicts was evaluated using simulation scenarios with and without pedestrian *** results revealed that pedestrian presence increased both V-V and V-P *** pedestrian presence increased the total number of traffic conflicts,permissive left-turn phasing processed fewer left-turn vehicles to maintain the same level of intersection safety with pedestrian presence compared to the no-pedestrian *** current left-turn phasing decision guidelines do not consider the impacts of pedestrian presence,this research quantified pedestrian-influenced and pedestrian-involved left-turn traffic conflicts to determine appropriate left-turn signal phasing decisions to ensure safe and efficient crossing of pedestrians and vehicles at signalized *** simulation-based study’s findings can be beneficial in the decision making of left-turn phasing selection as the before-after intersection safety performance analysis by collecting field data often resources intensive.

关键词： V-V conflicts V-P conflicts Left-turn phasing Pedestrian Warrants

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Development of New Submergence Tolerant Rice Variety for Bangladesh Using Marker-Assisted Backcrossing

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Rice science 2015年第1期22卷 16-26页

作者： Khandakar md IFTEKHARUDDAULA Helal Uddin AHMED Sharmistha GHOSAL Zakiah rahman MONI Al AMIN md Shamsher ALI Plant Breeding Division Bangladesh Rice Research Institute

Submergence tolerant high yielding rice variety was developed using BR11 as a recipient parent applying foreground, phenotypic and background selection approaches. Recombinant selection was found essential to minimize linkage drag by BC2F2 generation. Without recombinant selection, the introgression size in the backcross recombinant lines （BRLs） was approximately 15 Mb on the carrier chromosome. The BRLs were found submergence tolerance compared to the check varieties under complete submergence for two weeks at Bangladesh Rice Research Institute, and produced higher yield compared to the isogenic Subl-line under controlled submerged condition. The BRL IR85260-66-654-Gaz2 was released as BRRI dhan52 in 2010, which was the first high yielding submergence tolerant variety in Bangladesh. BRRI dhan52 produced grain yield ranging from 4.2 to 5.2 t/hm2 under different flash flood prone areas of Bangladesh in three consecutive seasons. The study demonstrated the efficiency of recombinant selection and better adaptability of the newly released submergence tolerant high yielding variety in flash flood prone different areas of the country with respect to submergence tolerance and yield potential.

关键词： backcross recombinant line marker-assisted backcrossing recombinant selection rice submergence tolerance

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Investigation on the Ballistic Performance of Para-Aramid Fabric under Effects of Varied Inter-Yarn Friction,Woven Architecture,and Layer

Investigation on the Ballistic Performance of Para-Aramid Fa...

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作者： md Riazur rahman 中原工学院

学位级别：硕士

弹道冲击是一个非常复杂的力学过程,主要取决于目标材料的不同设计、厚度、强度、密度和弹丸参数。由于高强力、高模量纤维的发展,大量纺织织物用于防弹衣设计。本研究主要目的是分析不同织物结构、层数及纱线间摩擦力的织物靶板的防弹... 详细信息

弹道冲击是一个非常复杂的力学过程,主要取决于目标材料的不同设计、厚度、强度、密度和弹丸参数。由于高强力、高模量纤维的发展,大量纺织织物用于防弹衣设计。本研究主要目的是分析不同织物结构、层数及纱线间摩擦力的织物靶板的防弹性能。使用有限元模拟评估机织物在圆柱形弹丸以475 m/s的冲击速度下的防弹性能。该模型中织物设为边长为7.54 cm的正方形,采用四边夹紧的边界条件。层数变化为1、4、8和12层,纱线间摩擦力由静摩擦系数和动摩擦系数表示,设置了三个级别的纱线间摩擦力,考虑了五种织物结构包括平纹、五枚缎纹、八枚缎纹、十一枚缎纹和UD织物。主要从这些防弹织物靶板弹道冲击中的能量吸收、背面变形和失效机理等进行了分析。首先,研究了1层、4层、8层和12层的UD织物、平纹织物和五枚缎纹织物的防弹性能。随着纱线间摩擦力的增加,三种多层织物的总能量吸收、动能和应变能都增加,尤其是在多层条件下;而摩擦耗散能仅在纱线间摩擦力水平居中时达到峰值。织物结构对整体能量吸收的影响表现出这样一种趋势:当层数和纱线间摩擦都较大时,五枚缎纹织物成为能量吸收的最佳结构。通过应力分布分析,所有靶板都显示出在较低的纱线间摩擦力下,各层更容易断裂,而在相同的时刻,在较高纱线间摩擦力下各层仍然完好无损,且承担更多应力。此外,与其他两个织物结构靶板相比,多层缎纹织物靶板中剩余层中的应力分布更加均匀。由于缎纹结构是最好的吸能结构,在上述研究基础上,接着对比分析了五枚、八枚和十一枚不同浮长线的缎纹织物在纱线间摩擦力和层数下的弹道冲击性能。随着纱线间摩擦力的增加,三种不同层数和浮长缎纹织物的能量吸收都显著增加。对于浮长线的影响,由于较长的浮长线会使织物结构更松散,因此浮长较大的织物靶板变形较大。对于缎纹织物作为防弹层而言,浮长线并不是长度越长,其防弹性能越好。最后,从主、次纱线的作用、各层在多层体系中的作用、剪切应力和拉伸应力的传播等方面详细分析了五枚缎纹织物的弹道能量吸收机理和破坏机理。对于五枚缎纹织物,发现主纱线在冲击初期吸收更多的动能和应变能,而次生纱线在冲击后期吸收更多的动能和应变能。此外,纱线间摩擦力的增加会增强主次纱线的作用,使其吸收更多的能量。对于多层五枚缎纹织物靶板,随着纱线间摩擦的增加,系统中每层织物吸收的应变能和动能都会增大。然而,纱线间摩擦力增加也带了不利的影响,即虽加强前层织物的能量吸收性能,但削弱后层能量吸收性能。对于主纱线的断裂,在较高纱线间摩擦力下,前层的主纱线承受较大的拉应力和剪应力,而后层的纱线承受较小的拉应力和剪应力。

关键词：织物靶板弹道冲击能量吸收背面变形失效机理防弹性能

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Exploring the Role of Serum Cystatin C in Early Detection of Acute Kidney Injury among On-Pump Cardiac Surgery Patients: A Single-Center Investigation in Bangladesh

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World Journal of Cardiovascular Diseases（心血管病） 2024年第6期 363页

作者： md.Ahaduzzaman md.Abir Tazim Chowdhury Munama Magdum md.Saiful Islam Khan Satyajit Sharma Monoj Tiwari md.Abul Bashar Maruf md.Alauddin Omar Sadeque Khan md.Mostafizur rahman Mirza md.Nazmus Saquib

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Aeromonas veronii isolated from climbing perch(Anabas testudineus)suffering from epizootic ulcerative syndrome(EUS)

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Aquaculture and Fisheries 2023年第3期8卷 288-295页

作者： Rakib Ehsan Ashikur rahman Sulav Indra Paul md.Ali Arman Ador md.Shameul Haque Tasmina Akter md.Mahbubur rahman Institute of Biotechnology and Genetic Engineering Bangabandhu Sheikh Mujibur Rahman Agricultural UniversityGazipur1706Bangladesh Department of Fisheries Management Faculty of FisheriesBangabandhu Sheikh Mujibur Rahman Agricultural UniversityGazipur1706Bangladesh

Motile Aeromonads are responsible for various diseases in fishes that cause significant economic losses in *** *** also frequently isolated from fish suffering from Epizootic Ulcerative Syndrome(EUS).The present study was conducted to isolate and identify *** from Vietnam climbing perch(Anabas testudineus)suffering from EUS,evaluate the pathogenicity of the isolates,and find out antibiogram profile and susceptibility of the isolates to medicinal plant *** climbing perch(***)suffering from EUS was collected from fish farms located at Savar,Dhaka and bacteria were isolated from the external ulcerative lesion,and kidney and liver of the infected fish on nutrient agar *** phenotypic identification of the bacterial isolates was performed following morphological,physiological and biochemical characterization *** 16S rRNA gene sequencing was accomplished for further molecular identification of five selected *** evaluate the pathogenicity of the isolates in vivo artificial infection challenge test was conducted through immersion *** in vivo pathogenicity test was done at three different temperatures(18◦C,28◦C,and 37◦C)to examine the effects of temperature on the pathogenicity of the *** commercial antibiotics were used to find out the antibiogram profile of the ***,susceptibility of the isolates was screened against 19 medicinal plants extracts.A total of 38 out of 46 isolates isolated from Vietnam climbing perch(***)suffering from EUS were phenotypically identified as Aeromonas *** randomly selected isolates were further confirmed as *** by analyzing the 16S rRNA gene sequence *** pathogenicity of the isolates was found moderate to high(41%-80%mortality)in the artificially challenged *** highest and lowest mortality was obtained in the fish challenged with the isolates BFKA33 and BFKA12,*** isolates were found resis

关键词： Aeromonas veronii Anabas testudineus,Epizootic ulcerative syndrome Antibiogram Medicinal plant extracts

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Braking Performance of a Biomimetic Squid-Like Underwater Robot

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Journal of Bionic Engineering 2013年第3期10卷 265-273页

作者： md. Mahbubar rahman Sinpei Sugimori Hiroshi Miki Risa Yamamoto Yugo Sanada Yasuyuki Toda Laboratory of Hull Form Design Department of Naval Architecture and Ocean Engineering Graduate School of Engineering Osaka University Osaka 565-0871 Japan

In this study, the braking performance of the undulating fin propulsion system ofa biomimetic squid-like underwater robot was investigated through free run experiment and simulation of the quasi-steady mathematical model. The quasi-steady equa- tions of motion were solved using the measured and calculated hydrodynamic forces and compared with free-run test results. Various braking strategies were tested and discussed in terms of stopping ability and the forces acting on the stopping stage. The stopping performance of the undulating fin propulsion system turned out to be excellent considering the short stopping time and short stopping distance. This is because of the large negative thrust produced by progressive wave in opposite direction. It was confirmed that the undulating fin propulsion system can effectively perform braking even in complex underwater explorations.

关键词： biomimetics squid-like underwater robot undulating fin propulsion system braking performance motion simulation

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Determinants of emergency contraceptive pill use in Bangladesh: An analysis of national survey data

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Asian pacific Journal of Reproduction 2022年第2期11卷 62-69页

作者： md.rahman Mahfuzur md.Rashed Alam md Arif Billah Department of Population Science and Human Resource Development University of RajshahiRajshahi 6205Bangladesh Department of Social Work and Counselling Faculty of BusinessEconomic and Social DevelopmentUniversiti Malaysia Terengganu21030 Kuala NerusTerengganuMalaysia

Objective:To examine the determinants of emergency contraceptive pill use in ***:Data for this cross-sectional study came from 2017-2018 Bangladesh Demographic and Health *** of 906 reproductive age women who were potential candidates for using emergency contraceptive pill were analysed in this *** were analysed using univariate and multivariate *** binary logistic regression was employed as multivariate ***:Only 10.9%candidates were found to ever use emergency contraceptive *** odds of using emergency contraceptive pill for women visited by family planning field worker was significantly higher than that for those who were not visited by family planning field worker[odds ratio(OR)1.94;95%confidence interval(CI)1.19–3.17;P=0.008],while the odds of using emergency contraceptive pill for women with high socioeconomic status was higher than that for those with low socioeconomic status(OR 3.10;95%CI 1.61–5.97;P=0.001).Additionally,having some media access was linked to an increase in the odds of using emergency contraceptive pill(OR 3.01;95%CI 1.33–6.83;P=0.008).Women empowerment related factors did not show any significant effect on emergency contraceptive pill ***:The findings indicate that family planning programme has a great opportunity of playing an important role in increasing emergency contraceptive pill use in Bangladesh by increasing the knowledge and awareness of women about emergency contraceptive pill.

关键词： Emergency contraceptive pill Unintended pregnancy Abortion Bangladesh Demographic and Health Survey Bangladesh

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Optimal treatment strategies to control acute HIV infection

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Infectious Disease Modelling 2021年第1期6卷 1202-1219页

作者： Shohel Ahmed Sumaiya rahman md Kamrujjaman Department of Mathematics Bangladesh University of Engineering and TechnologyDhaka1000Bangladesh Department of Statistics University of DhakaDhaka1000Bangladesh Department of Mathematics University of DhakaDhaka1000Bangladesh

Various antiretroviral therapies(ART)are administered to symptomatic human immunodeficiency virus(HIV)infected individuals to improve their *** treatment effectiveness may depend on suppressing development of drug resistance,reduce evolution of new viral strains,minimize serious side effects and the costs of *** paper deals with some results concerning optimal drug administration scheme successful in improving patients'health especially in poorly resourced *** model under consideration describes the interaction between the uninfected cells,the latently infected cells,the productively infected cells,and the free ***,in viral infection,the drug strategy aspects either the virus infectivity or reduce the virion *** mathematical model proposed here,deals with both situations with the objective function based on a combination of maximizing benefit relied on T cells count(the white cells that coordinate activities of the immune system)and minimizing the systemic *** existence of the optimal control pair is established and the Pontryagin's minimum principle is used to characterize these two optimal *** optimality system is derived and solved numerically using the forward and backward sweep method(FBSM).Our results indicate that early initiation of treatment makes a profound impact in both improving the quality of life and reducing the economic costs of therapy.

关键词： HIV Mathematical model Critical efficacy Optimal control Combined therapy

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Can picnic influence floral diversity and vitality of trees in Bhawal National Park of Bangladesh?

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Forestry Studies in China 2009年第3期11卷 148-157页

作者： md. Mizanur rahman Harald VACIK Institute of Silviculture Department of Forest and Soil Sciences University of Natural Resources and Applied Life Sciences Vienna A-1190 Austria

We examined the impact of picnic activities on forest diversity, structure, regeneration and vitality of tree species in the Bhawal National Park of Bangladesh. The study area was classified as a non-used, occasionally used and frequently used area on the basis of the intensity of the picnic activities. A total of 43 plant species were enumerated in the whole study area. The highest plant species richness （41 species） was observed in the non-used area whereas the lowest species richness （11 species） in the frequently used area. The diversity index decreased with the increase of picnic intensity whereas the concentration of dominance increased. Density of all plant groups except mature trees, and the basal area of the mature trees showed a declining trend from the non-used to frequently used area. The frequently used area exhibited very poor regeneration. Tree vitality decreased with the increase of picnic intensity. The relevance of our study as a basis for further research to determine the impact of tourism on biodiversity in Bangladesh is discussed.

关键词： species richness diversity index concentration of dominance regeneration intensity

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