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Comparative study of hypoglycemic and antibacterial activity of organic extracts of four Bangladeshi plants

Journal of Coastal Life Medicine 2016年第3期4卷 231-235页

作者： Mohammad Shah Hafez Kabir Shabbir Ahmad md.sofi mahamoud Nishan Chakrabarty md.Akramul Hoque Mohammed Munawar Hossain md.Nazim Uddin Chy Mohammed Shoibe Department of Pharmacy International Islamic University ChittagongChittagongBangladesh

Objective:To examine hypoglycemic and antibacterial activity against some Gram-positive and Gram-negative bacteria of organic extracts of four Bangladeshi ***:An in vivo hypoglycemic effect on mice model was used to check the hypoglycemic effect of four Bangladeshi herbal organic extracts viz.,roots of Curculigo recurvata ***(Satipata)(***),leaf of Amorphophallus bulbifer Roxb.(Olkachu)(***),whole plant of Thunbergia grandiflora Roxb.(Nillata)(***)and leaf of Steudnera colocasiifolia ***(Yunnan)(***)using glibenclamide as a positive control and water as a negative *** were also tested for antibacterial activity on three Grampositive and four Gram-negative bacteria by disk diffusion ***,*** and *** were extracted with methanol and *** was extracted with ***:Among all the plant extract,only ethanol extract of *** leaves at 800 mg/kg dose significantly(P<0.01)reduced fasting glucose level in normal mice as compared to standard drug glibenclamide(5 mg/kg).Ethanol extract of *** leaves at 800 mg/kg dose decreased 20.28%of blood glucose level after 2 h of administration in normal mice,where glibenclamide decreased 39.63%.Methanol extract of *** didn’t show any zone of inhibition against the tested bacteria,but other three extracts showed a wide range of zone of ***,none of the extract showed antibacterial activity against all the tested *** extract of *** showed maximum zone of inhibition against Bacillus cereus[(10.50±0.50)mm],Salmonella typhi[(16.20±1.26)mm],Escherichia coli[(13.00±1.00)mm]and ethanol extract of *** showed maximum zone of inhibition against Staphylococcus aureus[(11.20±1.26)mm],Bacillus subtilis[(12.00±0.50)mm],Salmonella paratyphi[(10.80±0.29)mm].Only methanol extract of *** showed(8.50±0.50)mm and(7.20±0.76)mm zone of inhibition against P

关键词： Curculigo recurvata Steudnera colocasiifolia Hypoglycemic Antibacterial Disc diffusion method

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Understanding hypothyroidism in Unani medicine

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Journal of Integrative Medicine 2019年第6期17卷 387-391页

作者： md.Anzar Alam Mohd Aleemuddin Quamri Ghulamuddin sofi Barkati md.Tarique Department of Moalajat National Institute of Unani MedicineBangalore 560091India Department of Ilmul Advia National Institute of Unani MedicineBangalore 560091India

Hypothyroidism(Qillat-e-Ifraz-e-Darqiyya) is a condition where the thyroid gland is underactive and unable to produce enough thyroid hormone. The description of hypothyroidism as a disease is not directly found in Unani texts. However, the signs and symptom of hypothyroidism resemble the clinical manifestation associated with Su-e-Mizaj Barid Maddi(derangement in cold temperament), such as plethora(Imtila), excessive salivation(Kasrat-e-Luabe-e-Dahan), tiredness(Aa'yan), loss of appetite(Zoaf-e-Ishteha), excessive sleeping(Kasrat-e-Naum) and cold skin(Baroodat-e-Jildia). These signs and symptoms are the result of an excess in abnormal phlegm(Ghair Tabayi Balgham) in the body. This review article identifies the observations from Unani literature that describe derangement in cold temperament and relate them to the clinical presentation of primary hypothyroidism in conventional medicine. We also discuss management of these symptoms in Unani medicine.

关键词： Hypothyroidism Qillat-e-Ifraz-e-Darqiyya Unani medicine Alternative medicine Complementary medicine

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