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Regeneration mechanisms and therapeutic strategies for neuromuscular junctions in aging and diseases

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Neural Regeneration Research 2025年第1期20卷 193-194页

作者： Masashi Fujitani abu md Mamun Tarif Yoshinori Otani Department of Anatomy and Neuroscience Faculty of MedicineShimane UniversityShimaneJapan

The neuromuscular junction(NMJ)is an essential synaptic structure composed of motor neurons,skeletal muscles,and glial cells that orchestrate the critical process of muscle contraction(Li et al.,2018).The typical NMJ structure is classically described as having a“pretzel-like”shape in mice(Figure 1),whereas human NMJs have a smaller,fragmented structure throughout *** NMJs exhibit smaller or fragmented endplates,partial denervation,reduced numbers of synaptic vesicles,abnormal presynaptic mitochondria,and dysfunctional perisynaptic Schwann cells(Alhindi et al.,2022).

关键词： aging structure Figure

Status and prospects for symmetric organic redox flow batteries

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Journal of Energy Chemistry 2025年第1期100卷 125-143页

作者： md Al Raihan C.Adam Dyker Department of Chemistry University of New Brunswick

As environmental concerns from fossil fuel consumption intensify, large-scale energy storage becomes imperative for the integration of renewable sources like wind, hydro, and solar with the electrical *** flow batteries, particularly those employing organic molecules, are positioned as a key technology for this purpose. This review explores the growing field of symmetric organic redox flow batteries(ORFBs) within this context. Unlike traditional asymmetric designs based on unique active materials for each electrode, symmetric ORFBs involve a single bipolar species for both electrodes. This review highlights the benefits of a symmetric design, and categorizes five distinct classes of organic bipolar molecules used in both aqueous and non-aqueous solvents. By providing a comprehensive overview of their cell cycling and performance characteristics, the strengths and weaknesses of the diverse categories of bipolar molecules are highlighted for both solvent systems, as are opportunities for future development. This should guide new research directions and advance the development of practical symmetric ORFBs.

关键词： Redox flow battery Symmetric battery Organic battery Aqueous electrolyte Non-aqueous electrolyte

Microforming of superplastic 5083 aluminum alloy

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中国有色金属学会会刊：英文版 2012年第S3期22卷 656-660页

作者： md.abu Mowazzem HOSSAIN Sung-Tae HONG Kyu-Yeol PARK Young-Sang NA School of Mechanical Engineering University of Ulsan Korea Institute of Materials Science

The mechanical behavior of superplastic 5083 aluminum alloy during microforming process was investigated by finite element analysis.A micro V-groove die was modeled to analyze the effects of forming time,load and temperature on the microformability of the 5083 aluminum ***,the microformability of the 5083 aluminum alloy was estimated using a microformability *** simulation results show that the microformability increases with the forming load,time and temperature *** of the 5083 aluminum alloy during microforming using the V-groove die was also investigated in terms of the effective strain *** results show that the superplasticity of the 5083 aluminum alloy occurs in a specific part of the material for a specific period during the microforming process depending on the forming conditions and the microformability index.

关键词： microforming superplasticity 5083 aluminum alloy

Hydrobiological variables as a regulatory factor on the abundance of heterotrophic flagellates in an urban pond

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Journal of Oceanology and Limnology 2019年第3期37卷 1030-1036页

作者： BEGUM Moni JEWEL md.abu Sayed HAQUE md.Ayenuddin KHATUN Mst.Samsad Department of Fisheries Faculty of Agriculture University of Rajshahi

The seasonal abundance of flagellates has been monitored over a period of 1 year from December 2013 to November 2014(divided into 4 conjugative seasons namely winter,spring,summer,and autumn)in an experimental pond located in Rajshahi City Corporation area,*** our knowledge,this study is the fi rst to shed light on the occurrence and possible interrelationships among heterotrophic flagellates(HF),bacteria and zooplankton in Bangladesh and the result obtained by this study will be beneficial for similar water ecosystem all over the *** methods were used to determine the prescribed hydrological parameters and zooplankton cell *** HF abundance(14 346.00 cells/mL)was found in the spring and the minimum(5 215.00 cells/mL)occurred in the *** to HF,significantly(Pabundance was found during the winter(782.00±47.62 cells/mL)and the lowest value was found in the autumn(448.00±39.15 cells/mL).Whereas similar to the HF,total bacterial abundance was significantly higher during the spring((2.25±1.05)×10^5 cells/mL)and lower in the summer((0.79±0.06)×10^5 cells/mL).Multivariate analyses(ANOSIM and mdS)have shown significant seasonal differences for cell numbers where mdS ordination plot and cluster analysis based on similarity in the genera abundance of HF revealed overlapping condition between winter and *** correspondence analysis(CCA)also showed a distinct separation among the genera based on the prevailing hydrological situation and indicated that temperature,pH,BOD5,and NO3^-were the most important environmental variables in determining the observed variation in HF community *** the biological factors,zooplankton showed negative but total bacteria were positively correlated with HF abundance.

关键词： heterotrophic flagellates abundance hydrobiological factors urban pond

Water and sediment quality parameters in the Chalan Beel, the largest wetland of Bangladesh

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Chinese Journal of Oceanology and Limnology 2015年第4期33卷 895-904页

作者： SAYEED md.abu HOSSAIN Mostafa Ali Reza WAHAB md.Abdul HASAN md.Tawheed SIMON Kumar Das MAZUmdER Sabuj Kanti Faculty of Fisheries Sylhet Agricultural University Faculty of Fisheries Bangladesh Agricultural University School of Environmental and Natural Resource Sciences Faculty of Science and Technology Universiti Kebangsaan Malaysia Marine Ecosystem Research Center Faculty of Science and Technology Universiti Kebangsaan Malaysia

A study was conducted to investigate the status of the water and sediment quality in the Chalan Beel——a major fresh water fish reservoir of the country for a period of one year from July 2007 to June 2008. The mean values of water quality parameters(depth: 214.73±152.22 cm, temperature 27.68±4.26℃, transparency 123±82 cm, p H 9.7±0.47, total alkalinity 137±42 mg/L, conductivity 307±147 μs/cm, total dissolved solids 183±89 mg/L, ammonia-N 0.27±0.39 mg/L, nitrate-N 0.09±0.07 mg/L, phosphate-P 2.01±2.53 mg/L) and sediment quality parameters(p H 7.21±0.35, organic matter 2.59±0.52%, total nitrogen 0.09±0.04%, available phosphorus 5.4±3.6 Meq./100 g and exchangeable potassium 0.43±0.14 Meq./100 g) were within the range recommended for most of the inland fishes of Bangladesh. Although the water and sediment quality parameters except ammonia and phosphate are in the suitable range, the overall results suggest that better management techniques should be practiced in order to overcome the declining trend of associated aquatic life(fauna and flora) of this important fresh water body of Bangladesh.

关键词： Chalan Beel total dissolve solids transparency residual effect organic matter sustainable management

Analytical behavior of weakly dispersive surface and internal waves in the ocean

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Journal of Ocean Engineering and Science 2022年第4期7卷 305-312页

作者： Mohammad Asif Arefin md.abu Saeed M.Ali Akbar M.Hafiz Uddin Department of Mathematics Jashore University of Science and TechnologyJashore7408Bangladesh Department of Applied Mathematics University of RajshahiRajshahi6205Bangladesh

The(2+1)-dimensional interaction of a Riemann wave propagating along the y-axis with a long wave along the x-axis is described by the space-time fractional Calogero-Degasperis(CD)and fractional poten-tial Kadomstev-Petviashvili(PKP)*** can be modeled according to the Hamiltonian structure,the lax pair with the non-isospectral problem,and the pain level *** proposed equations are widely used in beachfront ocean and coastal engineering to describe the propagation of shallow-water waves,demonstrate the propagation of waves in dissipative and nonlinear media,and reveal the propagation of waves in dissipative and nonlinear *** this paper,we have established further exact solutions to the nonlinear fractional partial differential equation(NLFPDEs),namely the space-time fractional CD and fractional PKP equations using the modified Rieman-Liouville fractional derivative of Jumarie through the two variable(G/G,1/G)-expansion *** far as trigonometric,hyperbolic,and rational function so-lutions containing parameters are concerned,solutions are acquired when unique characteristics are as-signed to the ***,the solitary wave solutions are generated from the solutions of the traveling *** is important to observe that this method is a realistic,convenient,well-organized,and ground-breaking strategy for solving various types of NLFPDEs.

关键词： Two variable(G/G,1/G)-expansion method Exact solution Traveling wave solutions Solitary wave solutions The space-time fractional CD equation The space-time fractional PKP equation

Ru/NiMnB spherical cluster pillar for highly proficient green hydrogen electrocatalyst at high current density

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Journal of Energy Chemistry 2025年第1期100卷 397-408页

作者： md Ahasan Habib Shusen Lin Mehedi Hasan Joni Sumiya Akter Dristy Rutuja Mandavkar Jae-Hun Jeong Jihoon Lee Department of Electronic Engineering College of Electronics and Information Kwangwoon University

Advanced OER/HER electrocatalytic alternatives are crucial for the wide adaptation of green hydrogen ***,Ru/NiMnB spherical cluster pillar （SCP）,denoted as Ru/NiMnB,is synthesized using a combination of electro-deposition and hydrothermal *** investigation of Ru doping in the NiMnB matrix revealed significant improvements in electrocatalytic *** Ru/NiMnB SCPs demonstrate superior OER/HER activity with low overpotentials of 150 and 103 mV at 50mA/cm2in 1 M KOH,making them highly competitive with state-of-the-art ***,the Ru/NiMnB SCPs exhibit a low 2-E cell voltage of 2.80 V at ultra-high current density of 2,000 m A/cm2in 1 M KOH,outperforming the standard benchmark electrodes of RuO2||Pt/C,thereby positioning Ru/NiMnB as one of the best bifunctional *** SCPs exhibit exceptional high-current characteristics,stability and corrosion resistance,as evidenced by continuous operation at 1,000 mA/cm2high-current density for over 150 h in 6 M KOH at elevated temperatures under harsh industrial *** a small amount of Ru incorporation significantly enhances the electrocatalytic performances of NiMnB,attributed to increased active sites and improved intrinsic properties such as conductivity,adsorption/desorption capability and reaction ***,Ru/NiMnB SCPs present a promising bi-functional electrode concept for efficient green H2production.

关键词： Advanced electrocatalyst High current Corrosion resistance Industrial requirement

Potential bioactive phytochemicals, antioxidant properties and anticancer pathways of Nymphaea nouchali

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Asian Pacific Journal of Tropical Biomedicine 2020年第12期10卷 555-562页

作者： md.Nazim Uddin md.Abdus Samad md.abu Zubair md.Zahurul Haque Kanika Mitra Tanzir Ahmed Khan md.Amir Hossain Ashikujaman Syed Aklima Afroze Institute of Food Science and Technology Bangladesh Council of Scientific and Industrial ResearchDhaka 1205Bangladesh School of Basic Medicine and Clinical Pharmacy China Pharmaceutical UniversityNanjingJiangsu 211198China Department of Food Technology and Nutritional Science Mawlana Bhashani Science and Technology UniversitySantoshTangail 1902Bangladesh Center for New Drug Safety Evaluation and Research China Pharmaceutical UniversityJiangsuNanjing 211198China School of Pharmacy Lanzhou UniversityLanzhou 730000China School of Pharmacy China Pharmaceutical UniversityNanjingJiangsu 211198China

Objective:To investigate bioactive phytochemicals and antioxidant activities of Nymphaea nouchali and to explore its anticancer pathways by a network pharmacology ***:Using a spectrophotometer and high-performance liquid chromatography-diode array detector(HPLC-DAD),we quantified bioactive phytochemicals in methanolic extract of Nymphaea nouchali *** extracts were investigated for in vitro antioxidant *** of these bioactive phytochemicals were predicted and anticancer-associated pathways were analyzed by a network pharmacology ***,we identified the predicted genes associated with cancer pathways and the hub genes in the protein-protein interaction network of predicted ***:Quantitative results indicated the total phenolics,total flavonoids,and total proanthocyanidins in the methanolic extract of Nymphaea nouchali ***-DAD analysis showed rutin(39.44 mg),catechin(39.20 mg),myricetin(30.77 mg),ellagic acid(11.05 mg),gallic acid(3.67 mg),vanillic acid(0.75 mg),rosmarinic acid(4.81 mg),p-coumaric acid(3.35 mg),and quercetin(0.90 mg)in 1 g of dry *** extract showed the radical scavenging activities of 2,2-diphenyl-1-picrylhydrazyl,2,2’-azinobis(3-ethylbenzothiazoline-6-sulfonic acid)and N,*** using network pharmacology,we predicted 130 target genes associated with cancer *** top hub genes(IL6,AKT1,EGFR,JUN,PTGS2,MAPK3,CASP3,and CXCL8)were also identified,which were associated with cancer pathways and interacted with bioactive phytochemicals of the methanolic extract of Nymphaea nouchali ***:Our study provides insights into the mechanism of anticancer activities of the methanolic extract of Nymphaea nouchali tuber.

关键词： Bioactive phytochemicals Anticancer pathways Malignancy Network pharmacology Nymphaea nouchali

A Study on Heat Transfer Enhancement through Various Nanofluids in a Square Cavity with Localized Heating

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Energy Engineering 2021年第6期118卷 1659-1679页

作者： Sheikh Hassan Didarul Ahasan Redwan md.Mamun Molla Sharaban Thohura M.abu taher Sadia Siddiqa Department of Mathematics and Physics North South UniversityDhakaBangladesh Center for Applied and Scientific Computing(CASC) North South UniversityDhakaBangladesh Department of Mathematics Jagannath UniversityDhakaBangladesh Department of Mathematics Dhaka University of Engineering and TechnologyGazipurBangladesh Department of Mathematics COMSAT University IslamabadAttock CampusAttockPakistan

A two-dimensional(2D)laminar flow of nanofluids confined within a square cavity having localized heat source at the bottom wall has been *** governing Navier–Stokes and energy equations have been non dimensionalized using the appropriate non dimensional variables and then numerically solved using finite volume *** flow was controlled by a range of parameters such as Rayleigh number,length of heat source and nanoparticle volume *** numerical results are represented in terms of isotherms,streamlines,velocity and temperature distribution as well as the local and average rate of heat transfer.A comparative study has been conducted for two different base fluids,ethylene glycol and water as well as for two different solids Cu and Al_(2)O_(3).It is found that the ethylene glycol-based nanofluid is superior to the water-based nanofluid for heat transfer enhancement.

关键词： Nanofluids finite volume method heat transfer enhancement localized heating