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Post Thyroidectomy Assessment of Intact Parathyroid Hormone for Early Prediction of Hypocalcaemia

International Journal of Otolaryngology and Head & Neck Surgery 2024年第2期13卷 71-84页

作者： md. Masum Billah Ripon Kumar Sarkar md. Yousuf Ali Saad Zaman md. nazmul hasan md. Shehab Uddin md. Mosleh Uddin Kazi Shameemus Salam Farzana Binte Abedin Leera Department of Otolaryngology-Head & Neck Surgery Universal Medical College Hospital Dhaka Bangladesh Department of Otolaryngology-Head & Neck Surgery National Institute of Ear Nose and Throat Dhaka Bangladesh Shaheed Ahsan Ullah Master General Hospital Gazipur Bangladesh Department of Otolaryngology-Head & Neck Surgery Cumilla Medical College Cumilla Bangladesh Department of ENT Oncology National Institute of Cancer Research & Hospital Dhaka Bangladesh Department of ENT Outdoor Rajshahi Medical College Hospital Rajshahi Bangladesh Department of Otolaryngology-Head & Neck Surgery Bangabandhu Sheikh Mujib Medical University Dhaka Bangladesh Department of Biochemistry Delta Medical College Hospital Dhaka Bangladesh

Background: As the half-life of intact parathyroid hormone (iPTH) is very low, it reflects parathyroid insufficiency within minutes to hours after total thyroidectomy. Therefore, iPTH level assessment in the postoperative period can be used to predict the development of hypocalcaemia. The optimal time point to measure serum iPTH is important for the accurate prediction of hypocalcaemia. Aim: This paper aims to evaluate the ability of iPTH as an early predictive marker of hypocalcaemia and determine which time iPTH is more able to predict postoperative hypocalcaemia. Method: This prospective observational study was conducted in the Department of Otolaryngology-Head & Neck Surgery, BSMMU, Dhaka, from July 2020 to December 2021, with 67 patients who underwent total thyroidectomy. iPTH levels were measured on the day before the operation and at 1 hour, 4 hours, and 24 hours after the operation. *** levels were measured on the day before the operation and 1st postoperative day. All the data were compiled and sorted properly and were analyzed statistically. Results: Postoperative hypocalcaemia developed in 18 cases, with an incidence of 26.9%. Pearson correlation showed a significant correlation between postoperative iPTH at 1 hr, 4 h, and 24 hr with 1st postoperative calcium value. The Receiver operating characteristic (ROC) curve was processed for the postoperative iPTH at 1 hr, 4 h, and 24 hr. The sensitivity, specificity, cut-off value, and mean AUC found 93.9%, 94.4%, ≤14.0, 0.988;95.9%, 94.4%, ≤09.5, 0.993 and 91.8%, 94.4%, ≤11.0, 0.993 respectively. Conclusion: iPTH can be used as an early predictor of post-thy-roidectomy hypocalcaemia. 4 hr iPTH showed more sensitivity and specificity for a cut-off value near the laboratory reference range.

关键词： Total Thyroidectomy Hypocalcaemia Serum Intact Parathyroid Hormone Early Predictor of Hypocalcaemia

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Complete separation of the urinary tract from proximal rectum during PSARP surgery: our experience with the novel technique

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World Journal of Pediatric Surgery 2024年第1期7卷 66-69页

作者： md.Samiul hasan md.nazmul Islam Refoyez Mahmud Umama Huq Ashrarur Rahman Pediatric Surgery Bangladesh Shishu Hospital and InstituteDhakaBangladesh

Anorectal malformation(ARM)is a frequently occurring surgical condition in neonates,with a prevalence of 1 in 4000 live births.'In boys with this anomaly,the rectum and urinary tract share a common wall for some distance,often ending up in fistulous *** goals of definite reconstruction are to separate the rectum from the urinary tract without injuring the urethra and mobilizing the rectum to the perineum within the muscle *** the rectum and the urinary tract is the most critical part of this operation and is associated with a significant risk of urinary tract injury.2-5 The original procedure described by Pena and Devries involves multiple stay sutures on the rectal mucosa just above the fistula,lifting the mucosa and continuing a submucosal dissection up to the prostate,where the entire thickness of the intestine can be separated from the urinary tract.

关键词： urinary rectum intestine

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Estimation of Vitamins B-Complex (B2, B3, B5and B6) of Some Leafy Vegetables Indigenous to Bangladesh by HPLC Method

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Journal of Analytical Sciences, Methods and Instrumentation 2013年第3期3卷 24-29页

作者： md. nazmul hasan M. Akhtaruzzaman md. Zakir Sultan Centre for Advanced Research in Sciences Uni- versity of Dhaka Dhaka Bangladesh Institute of Nutrition and Food Science University of Dhaka Dhaka Bangladesh

The current experiment was conducted for the simultaneous determination of several water-soluble vitamins like ribo- flavin (vitamin B2), niacin (vitamin B3), pantothenic acid (vitamin B5) and pyridoxine (vitamin B6) in five highly con- sumed local leafy vegetables named as bottle gourd leaves (Lagenaria vulgaris) (local name Lau shak), green amaranth leaves (Amaranthus viridis) (local name Data shak), red amaranth leaves (Amaranthus gangeticuss) (local name Lal shak), Indian spinach (Basella alba) (local name Pui shak) and bitter gourd leaves (Momordica charantia) (local name Korola shak). The analyses were performed by HPLC using an analytical reversed phase C-18 (ODS column, 250 × 4.6 mm, 5 μm, Phenomenex, Inc.) column with the mobile phase consisting of a mixture of buffer (hexane sulphonic acid sodium, potassium dihydrogen phosphate and triethylamine, pH 3.0) and methanol in the ratio of 96:4 (v/v) at a flow rate of 1 mL/min with UV detection at 210 nm. The retention times for the vitamins were obtained as 3.61 min, 6.37 min, 9.51 min and 11.51 min for Vitamins B2, B3, B5 and B6, respectively. These obtained values of the vitamins were compared with the values available in published literatures of Deshio Khaddar Pustiman (DKPM), Indian food value (IFV) and United States Department of Agriculture (USDA).

关键词： HPLC Analysis Vitamin B2 Vitamin B3 Vitamin B5 Vitamin B6 Leafy Vegetables

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Physico-Chemical and Microbiological Quality Assessment of Supply Water around Dhaka City, Bangladesh

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Journal of Water Resource and Protection 2019年第3期11卷 280-295页

作者： md. Shamimuzzaman Rashed hasan Nayeem Nargis Ara md. Masuder Rahman md. Iqbal Kabir Jahid md. nazmul hasan Department of Microbiology Faculty of Biological Science and Technology Jessore University of Science and Technology Jessore Bangladesh Biotechnology and Genetic Engineering Discipline School of Life Sciences Khulna University Khulna Bangladesh Department of Pharmacy University of Development Alternative Dhaka Bangladesh Department of Biotechnology and Genetic Engineering Mawlana Bhashani Science and Technology University Tangail Bangladesh Department of Genetic Engineering and Biotechnology Faculty of Biological Science and Technology Jessore University of Science and Technology Jessore Bangladesh

Dhaka is one of the most densely-populated megacities in the world. Water supply problem is acute in this city, but the quality of drinking water has tremendous importance as potability. This study was aimed at comparing various physicochemical and microbiological parameters which are very much relevant for the drinking water quality of Dhaka city of Bangladesh. A total of 80 samples from 11 collection point of different places were collected over ten months. After that, the samples were examined by a different measuring device for physicochemical parameter testing. Considering physicochemical parameters, all water samples were within the limit for pH. However, 53.75% water had unsatisfactory for chlorine level. Total Dissolve Solid (TDS), hardness, iron, and alkalinity based unsatisfactory were 28.75%, 15.0%, 8.75%, and 3.75% respectively. Five parameters had taken into consideration to measure the microbiological quality. The cultural and biochemical methods showed that 80 water samples have a different range of contamination. The total aerobic count was unsatisfactory for 53.75% samples. Sixty-one samples were found coliform contaminated that is 76.25% of the total samples and 58.75% sample was carried fecal substances. E. coli and Vibrio was unsatisfactory as 61.25% and13.75% respectively. This study revealed that how much safe is supplied water of a municipal water supplier.

关键词： Water Quality Microbial Assay Coliform Fecal Coliform Chlorination Potability Physicochemical Properties of Water Pathogen

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In-VitroRegeneration of Citrus sinensis(L.) Osbeck from Mature Seed Derived Embryogenic Callus on Different Solid Basal Media

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American Journal of Plant Sciences 2019年第2期10卷 285-297页

作者： md. nazmul hasan Mohammed Raqibul hasan Shakhawat Hossain Foysal Hammadul Hoque md. Fahim Khan md. Fahmid Hossain Bhuiyan Shamsul H. Prodhan Department of Genetic Engineering and Biotechnology Shahjalal University of Science and Technology Sylhet Bangladesh

In-vitro callus induction and regeneration method was developed using different plant growth regulators (PGRs), and basal media (Murashige and Skoog (MS), CHU (N6) and Gamborg (B5) media) of Citrus sinensis (L.) Osbeck. Observations of the effect of PGRs were carried out using different concentrations of 2,4-dichlorophenoxyacetic acid (2,4-D),1-naphthalene acetic acid (NAA) and combinations of 2,4-D and NAA using different basal media. This study found Citrus sinensis (L.) Osbeck exhibited a high frequency of callus induction on MS medium supplemented with 3 mg/L 2,4-D and callus induction frequency was 86.7% ± 3.4% whereas N6 and B5 showed lower callus induction frequency of 83.3% ± 8.8% and 82.2% ± 1.9% respectively compared to that of MS media with supplementation of the same hormone. Among the induced calli, the morphological analysis showed only 40% - 50% was embryogenic calli. Regeneration of plantlets from calli was done using different concentrations and combinations of auxin and cytokinin. The study showed that 3 mg/L 6-benzylaminopurine (BAP) supplemented medium has the maximum potential to promote regeneration of Citrus sinensis (L.) Osbeck from embryogenic calli with the frequency of 89.3% ± 8.8% but no regeneration occurred from the non-embryogenic calli. The regenerated plantlets were rooted on MS medium with supplementation of 5 mg/l NAA. These observations in Citrus sinensis (L.) Osbeck regeneration will be helpful for genetic improvement with desired traits.

关键词： Citrus sinensis (L.) Osbeck PGRs Basal Media Regeneration

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Personal Hygiene Concept, Knowledge, and Awareness Regarding COVID-19 among Bangladeshi People

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Journal of Biosciences and Medicines 2021年第8期9卷 73-91页

作者： N. M. Mahmudul Alam Bhuiya Sazzad Ahmed md. nazmul hasan md. Tanveer Ahsan Oli Ahmed Department of Pharmacy Faculty of Life and Earth Sciences Jagannath University Dhaka Bangladesh Department of Pharmacy Faculty of Biological Sciences University of Chittagong Chittagong Bangladesh Department of Psychology Faculty of Biological Sciences University of Chittagong Chittagong Bangladesh

Aim: Novel coronavirus disease 2019 (COVID-19) has emerged as an unknown fallacy that forced into a global pandemic. Only a few vaccines are available for a limited number of people, and most of the population are not vaccinated yet. So, social distancing, proper personal hygiene, and sanitization concepts are the main factors to prevent the spread of this disease. For a densely populated country like Bangladesh, the concepts of social distancing are unpopular, and people are reluctant to follow community health guidelines. This study aimed to understand the personal hygiene concept, knowledge, and awareness of Bangladeshi people against COVID-19. Subject and Methods: This cross-sectional study was conducted from March to June 2020 through an online Google survey. Those who answered all the questions were finally included for result calculation (n = 182). The chi-square test was applied to evaluate the correlations among the groups based on education, income level, and occupation. Results: The results showed that education level and occupational status play a vital role in awareness about the general symptoms of COVID-19. Students have a lower rate of washing hands for 20 sec than people of other occupations (p = 0.037). The rate of using masks while going outside is not common in the low-income group (p = 0.010). A significant variation was also observed in wearing a mask when income level, education, and occupation were considered to compare among the groups. There was a noteworthy distinction in handwashing frequency and duration of handwashing in different occupation groups of the participants (p = 0.044 and 0.008, respectively). On the other hand, graduates were found comparatively more concerned about maintaining home quarantine and isolation firmly than others. They know the differences and significance of these two interventions properly. Conclusion: More comprehensive education programs cou

关键词： Personal Hygiene Concept Coronavirus COVID-19 Coronavirus Awareness Bangladesh

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Incidence, Risk Factors and Short Term Outcome of Acute Kidney Injury among Patients with Acute Coronary Syndrome

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Journal of Biosciences and Medicines 2020年第5期8卷 177-188页

作者： md. Kabir Hossain Muhammad Rafiqul Alam Asia Khanam A. K. M. Shahidur Rahman Rafi Nazrul Islam Syed Fazlul Islam Mohammad Kamrul Ahsan S. K. Mamun-Ar-Rashid Tanvir Rahman md. nazmul hasan Department of Nephrology Bangabandhu Sheikh Mujib Medical University (BSMMU) Dhaka Bangladesh Department of Nephrology & Dialysis BIRDEM General Hospital Dhaka Bangladesh Holy Family Red Crescent Medical College Hospital (HFRCMCH) Dhaka Bangladesh Department of Medicine Khulna Medical College Hospital Khulna Bangladesh Department of Nephrology United Hospital Limited Dhaka Bangladesh Department of Cardiology Ad-din Medical College Hospital Dhaka Bangladesh

Background: Cardio-renal syndrome is the leading cause of death globally. Acute kidney injury (AKI) is a major complication among patients admitted in Coronary Care Unit (CCU) with acute coronary syndrome (ACS). AKI in ACS patients is associated with higher morbidity, mortality and prolong hospital stay. Objective: To determine the incidence, risk factors and short term outcome of acute kidney injury (AKI) among the patients admitted in CCU with ACS. Methods: This cross sectional study was conducted at Department of Nephrology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from January 2013 to December 2013. Following selection criteria a total of two hundred (200) patients with ACS were studied. AKI was defined according to the KDIGO guideline and further categorized by RIFLE criteria. Data of patients with AKI and those without AKI were analyzed and compared by statistical tests. Results: Majority of the study patients were male (79.5%). AKI was developed in 40 of the 200 study patients (20.0%). The mean (±SD) age of the study patients was 60.1 ± 11.1 years in patients with AKI and 55.9 ± 10.1 years in patients without AKI. Our data analysis showed that older age (>65 years), diabetes mellitus, dyslipidemia and smoking were significantly correlated to the development of AKI. Mortality was significantly high in AKI group (7.15%) compared to no AKI group (1.25%). Out of 27 patients who achieved renal recovery most (80.8%) belonged to risk class. Severity of AKI showed significant effect on renal recovery and final outcome. Conclusion: This study demonstrated that, incidence of AKI among patients with ACS was 20%. Elderly patients, diabetes mellitus, dyslipidemia, and exposure to smoking were significantly associated with development of AKI in ACS.

关键词： Acute Kidney Injury (AKI) Acute Coronary Syndrome (ACS) Cardio-Renal Syndrome

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Chemically and biologically activated biochars slow down urea hydrolysis and improve nitrogen use efficiency

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Pedosphere 2023年第4期33卷 659-669页

作者： nazmul H.ANTOR Shamim MIA md.M.hasan Nowrose J.LIPI Keiji JINDO Miguel A.SANCHEZ-MONEDERO md.H.RASHID Department of Agronomy Patuakhali Science and Technology UniversityDumkiPatuakhali 8602(Bangladesh) Agrosystems Research Groups Wageningen University and ResearchWageningen 6700 AA(The Netherlands) Department of Soil and Water Conservation and Organic Waste Management Spanish National Research Council(CEBAS-CSIC)Murcia 30100(Spain)

Biochar is considered a potential technology to enhance chemical fertilizer use efficiency through intensification of the interactions between nutrients and the functional groups on biochar ***,little is known about how the application of activated biochars mixed with urea influences nitrogen(N)mineralization and crop performance in paddy ***,a sawdust-derived fresh biochar(FBC)(ca.400℃)was activated chemically with 15%hydrogen peroxide and biologically with a nutrient solution mixed with a soil inoculum to obtain a chemically activated biochar(CBC)and a biologically activated biochar(BBC),*** chemical and surface properties of FBC,CBC,and BBC were evaluated using spectroscopic methods,i.e.,Fourier transform infrared spectroscopy and 13C nuclear magnetic resonance,and potentiometric charge *** N retention capacity of biochars and their interaction with urea hydrolysis were examined in a laboratory incubation ***,a field experiment was carried out in a paddy field with the biochars unmixed or mixed with urea at a 1:1 *** results showed that negative surface functional groups and negative charges were increased on both activated biochars,especially *** activated biochars contributed to a significant reduction in urea-biochar suspension pH and increased N retention in the incubation *** the enhanced surface properties of the activated biochars,no similar increases in rice biomass and grain yield were observed for these biochars in the field ***,rice biomass,grain yield,apparent N use efficiency,and agronomic N use efficiency were significantly higher with the application of the three biochars compared to no-biochar ***,the results indicate that the application of urea mixed with biochar could enhance crop performance,especially in the case of activated biochar,which would enhance N retention in the soil,reducing N loss.

关键词： chemical property crop yield functionalized biochar nitrogen uptake nutrient use efficiency pyrolysis

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Efficient Finite Difference Methods for the Numerical Analysis of One-Dimensional Heat Equation

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Journal of Applied Mathematics and Physics 2023年第10期11卷 3099-3123页

作者： md. Shahadat Hossain Mojumd.r md. nazmul Haque md. Joni Alam Department of Mathematics Comilla University Kotbari Bangladesh Department of Mathematical Sciences Kent State University Kent OH USA

In this paper, we investigate and analyze one-dimensional heat equation with appropriate initial and boundary condition using finite difference method. Finite difference method is a well-known numerical technique for obtaining the approximate solutions of an initial boundary value problem. We develop Forward Time Centered Space (FTCS) and Crank-Nicolson (CN) finite difference schemes for one-dimensional heat equation using the Taylor series. Later, we use these schemes to solve our governing equation. The stability criterion is discussed, and the stability conditions for both schemes are verified. We exhibit the results and then compare the results between the exact and approximate solutions. Finally, we estimate error between the exact and approximate solutions for a specific numerical problem to present the convergence of the numerical schemes, and demonstrate the resulting error in graphical representation.

关键词： Explicit Scheme Implicit Scheme C-N Scheme CFL Condition

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Performance Improvement of CIGS Solar Cell: A Simulation Approach by SCAPS-1D

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Energy and Power Engineering 2023年第8期15卷 291-306页

作者： md. Ferdous Wahid md. Nuralam Howlader nazmul Ahasan md. Mizanur Rahman Department of Electrical and Electronic Engineering Hajee Mohammad Danesh Science and Technology University Dinajpur Bangladesh

Thin-film solar cells possess the distinct advantage of being cost-effective and relatively simple to manufacture. Nevertheless, it is of utmost importance to enhance their overall performance. In this research work, copper indium gallium selenide (CIGS)-based ultra-thin solar cell (SC) configuration (Ag/ZnO/ZnSe/CIGS/Si/Ni) has been designed and examined using SCAPS-1D. The numerical calculations revealed that this new design resulted in a substantial improvement in SC performance. This study explores the utilization of two absorber layers, CIGS and Si, both with a total of 2 μm thickness, to enhance device performance while reducing material costs, observing an increase in key SC parameters as the Si absorber layer thickness is increased, reaching a maximum efficiency of 29.13% when CIGS and Si thicknesses are set at 0.4 μm and 1.6 μm, respectively with doping absorber doping density of 1014 cm-3. Furthermore, we analyze the impact of variation in absorber and buffer layer thickness, as well as doping concentration, surface recombination velocity (SRV), electron affinity, series-shunt resistance, and temperature, on optimized CIGS SC parameters such as short-circuit current density (JSC), open circuit voltage (VOC), fill factor (FF), and power conversion efficiency (PCE). The findings yielded by the investigation offer significant elucidation regarding the fabrication of economically viable and highly efficient non-hazardous CIGS ultra-thin SC.

关键词： Thin-Flim CIGS-Based Solar Cell Non-Toxic Solar Cell SCAPS-1D Numerical Simulation Renewable Energy

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