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Mechanistic insights into fasting-induced autophagy in the aging heart

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World Journal of Cardiology 2024年第3期16卷 109-117页

作者： Hannaneh Parvaresh Katarzyna Paczek md abdul alim al-bari Nabil Eid Department of Biology Faculty of ScienceFerdowsi University of MashhadMashhad ***Iran Department of Chiropractic International Medical UniversityKuala Lumpur 57000Malaysia Department of Pharmacy University of RajshahiRajshahi 6205Bangladesh Department of Anatomy Division of Human BiologySchool of MedicineInternational Medical UniversityKuala Lumpur 57000Malaysia

Autophagy is a prosurvival mechanism for the clearance of accumulated abnormal proteins,damaged organelles,and excessive lipids within mammalian cells.A growing body of data indicates that autophagy is reduced in aging *** reduction leads to various diseases,such as myocardial hypertrophy,infarction,and *** studies in animal models of an aging heart showed that fasting-induced autophagy improved cardiac function and *** improvement is related to autophagic clearance of damaged cellular components via either bulk or selective autophagy(such as mitophagy).In this editorial,we summarize the mechanisms of autophagy in normal and aging *** addition,the protective effect of fasting-induced autophagy in cardiac aging has been highlighted.

关键词： Aging Autophagy Heart Fasting Mitophagy

Exploration of sex-specific and age-dependent COVID-19 fatality rate in Bangladesh population

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World Journal of Radiology 2021年第1期13卷 1-18页

作者： md abdul alim al-bari Showna Hossain md Kudrat-E Zahan 不详 Department of Pharmacy University of RajshahiRajshahi 6205Bangladesh Department of Chemistry University of RajshahiRajshahi 6205Bangladesh

Coronavirus disease-2019(COVID-19),a respiratory tract infection caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has become a global health emergency and a threat the entire *** COVID-19 shows a wide spectrum of clinical presentations,severity,and fatality *** the fatal outcomes of the COVID-19 pandemic are evident in all age groups,the most devastating impact on the health consequences and death from COVID-19 are associated with older adults,especially older ***-19 pandemic is affecting different countries in the world especially in the 65+years age male *** fact,several genes involved into the regulation of the immune system are strategically placed on the X-chromosome and trigger a gendered mediated antiviral *** aim of this study is to explore and exploit whether a relationship exists between male sex and COVID-19 mortality and the relationship is age *** we discuss the possible role of physiological and immunological sex differences into the higher morbidity and mortality of SARSCoV-2 between females and *** gender differences in COVID-19 offers a window into the principles of immunity against SARS-CoV-2 infection and this information on ageing dependent gender disparity might contribute to our current understanding of COVID-19 infection and disease treatment.

关键词： COVID-19 Gender Sex hormones Angiotensin-converting enzyme 2 TMPRSS2 TLR7

Potential Antidiabetic Activities of Probiotic Strains, <i>L. acidophilus</i>and <i>L. bulgaricus</i>against Fructose-Fed Hyperglycemic Rats

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Food and Nutrition Sciences 2019年第12期10卷 1419-1432页

作者： md Shihab Uddin Sohag Mollika Paul md abdul alim al-bari Mir Imam Ibne Wahed md Rafiqul Islam Khan Department of Pharmacy University of Rajshahi Rajshahi Bangladesh

Background: Deregulation of the gut microbiota results in various pathological disorders such as diabetes, inflammation, cancer, dyslipidemia etc. Modulation of intestinal microbiota by probiotics may facilitate the management of a number of clinical conditions of diabetes. Methods: The present study was designed to investigate the effect of feeding low-fat probiotic yogurt containing L. acidophilus and L. bulgaricus on fructose-fed hyperglycemic rats. Yogurt containing L. acidophilus or L. bulgaricus (9.5 × 109 cfu/rat/day) alone or in combination of both strains was supplied orally for 8 weeks concurrently with 20% fructose solution. Fasting blood glucose (FBG), oral glucose tolerance test, glycosylated hemoglobin (HbA1c), lipid profiles from blood and histopathological study of liver tissues were analyzed to evaluate anti-diabetic effect. Statistical analysis was done by Graph Pad Prism software. Values at p 0.05 were considered statistically significant. Results: Administration of L. acidophilus or L. bulgaricus alone or in combination of both to hyperglycemic rats decreased serum FBG, onset of glucose intolerance, HbA1c, total cholesterol, triglycerides, LDL and VLDL-cholesterol, increased HDL-cholesterol levels significantly and preserved antioxidant pool such as activities of superoxide dismutase, catalase etc. Probiotic administration also prevented/repaired the oxidative damage of liver tissues. Conclusion: In conclusion, administration of yogurt containing L. acidophilus or L. bulgaricus that balanced the intestinal microbiota can prevent or lower risks of type-2 diabetes and its related complications.

关键词： Probiotics Fructose-Fed Rats Hyperglycemia Dyslipidemia

An Enhanced Hybrid Model Based on CNN and BiLSTM for Identifying Individuals via Handwriting Analysis

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Computer Modeling in Engineering & Sciences 2024年第8期140卷 1689-1710页

作者： md.Abdur Rahim Fahmid al Farid Abu Saleh Musa Miah Arpa Kar Puza md.Nur alam md.Najmul Hossain Sarina Mansor Hezerul abdul Karim Department of Computer Science and Engineering Pabna University of Science and TechnologyPabna6600Bangladesh Faculty of Engineering Multimedia UniversityCyberjaya63100Malaysia Department of Computer Science and Engineering Bangladesh Army University of Science and TechnologySaidpur5311Bangladesh Department of Mathematics Pabna University of Science and TechnologyPabna6600Bangladesh Department of Electrical Electronic and Communication EngineeringPabnaUniversity of Science and TechnologyPabna6600Bangladesh Department of Electrical and Communication Engineering Pabna University of Science and TechnologyPabna6600Bangladesh

Handwriting is a unique and significant human feature that distinguishes them from one *** are many researchers have endeavored to develop writing recognition systems utilizing specific signatures or symbols for person identification through ***,such systems are susceptible to forgery,posing security *** response to these challenges,we propose an innovative hybrid technique for individual identification based on independent handwriting,eliminating the reliance on specific signatures or *** response to these challenges,we propose an innovative hybrid technique for individual identification based on independent handwriting,eliminating the reliance on specific signatures or *** innovative method is intricately designed,encompassing five distinct phases:data collection,preprocessing,feature extraction,significant feature selection,and *** key advancement lies in the creation of a novel dataset specifically tailored for Bengali handwriting(BHW),setting the foundation for our comprehensive ***-preprocessing,we embarked on an exhaustive feature extraction process,encompassing integration with kinematic,statistical,spatial,and composite *** meticulous amalgamation resulted in a robust set of 91 *** enhance the efficiency of our system,we employed an analysis of variance(ANOVA)F test and mutual information scores approach,meticulously selecting the most pertinent *** the identification phase,we harnessed the power of cutting-edge deep learning models,notably the Convolutional Neural Network(CNN)and Bidirectional Long Short-Term Memory(BiLSTM).These models underwent rigorous training and testing to accurately discern individuals based on their handwriting ***,our methodology introduces a groundbreaking hybrid model that synergizes CNN and BiLSTM,capitalizing on fine motor features for enhanced individual ***,our experimental results unde

关键词： Bengali handwriting(BHW) person identification convolutional neural network(CNN) BiLSTM

Correction‐enabled reversible data hiding with pixel repetition for high embedding rate and quality preservation

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IET Cyber-Systems and Robotics 2024年第3期6卷 49-61页

作者： Mohammad ali Kawser Hussain Nyeem md abdul Wahed School of Transportation Science and Engineering Beihang UniversityBeijingChina Department of Electrical Electronic and Communication Engineering(EECE)Military Institute of Science and Technology(MIST)DhakaBangladesh

A novel correction‐enabled Pixel Repetition(PR)‐based Reversible Data Hiding(RDH)framework,featuring a new embedding scheme is *** proposed RDH scheme uses contextually redundant block pixels,generated via PR,in a two‐phase adaptive embedding process,enhancing both image quality and data embedding ***,each 2×2 block encodes 4 bits of data using new mapping conditions that facilitate seed pixel reconstruction from remaining block pixels and provide additional embedding ***,an innovative post‐embedding error correction technique,based on 2^(k)‐bit error‐correction,minimises post‐embedding distortion,further improving image *** error correction approach augments data embedding robustness,vital for applications like medical imaging,telemedicine,and digital watermarking that requires high embedding capacity with minimum possible *** proposed scheme surpasses existing state‐of‐the‐art methods in embedding ratedistortion performance,validated through subjective and objective ***,statistical analysis,including histogram and fragility testing,confirms the scheme's potential for image authentication across diverse multimedia *** correctionenabled RDH with PR offers enhanced embedding capacity and image quality preservation,making it particularly advantageous for applications requiring robust data hiding while maintaining visual fidelity.

关键词： data assimilation vision

Characteristics of Multi-Objective Linear Programming Problem and Multi-Objective Linear Fractional Programming Problem Taking Maximum Value of Multi-Objective Functions

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Applied Mathematics 2024年第1期15卷 22-32页

作者： Samsun Nahar md. Asadujjaman Khadiza Begum Mahede-Ul-Hassan md. abdul alim Department of Basic Sciences and Humanities University of Asia Pacific Dhaka Bangladesh Department of Mathematics University of Dhaka Dhaka Bangladesh Computer Science and Engineering Department Prime University Dhaka Bangladesh Department of Mathematics and Statistics Bangladesh University of Business and Technology Dhaka Bangladesh Department of Mathematics Bangladesh University of Engineering and Technology Dhaka Bangladesh

In this paper, a new statistical averaging technique is proposed for finding an optimal solution to a multi-objective linear fractional programming problem (MOLFPP) and multi-objective linear programming problem (MOLPP) by using new arithmetic averaging method and new geometric averaging method. It is significantly noticeable same characteristics among all the technique while taking maximum or minimum among all optimized values for multi-objective functions using simplex algorithm. The characteristics provided from the problems are verified by the numerical examples.

关键词： MOLPP MOLFPP New Arithmetic Averaging Method New Geometric Averaging Method

A Critical Review of Community Resilience Building Framework: Contexts of Climate Change and Disasters in Bangladesh

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Journal of Geoscience and Environment Protection 2024年第9期12卷 315-334页

作者： abdul alim Shaikh Mousumi Halder Muhammad Ramzan ali Ruhul Amin md Saifur Rahman md. Kamruzzaman Khulna University Khulna Bangladesh Climate Change Program Christian Commission for Development in Bangladesh (CCDB) Dhaka Bangladesh International Rescue Committee-UK Coxs Bazar Bangladesh Tropical and International Forestry Technical University Dresden Cotta Bau Pienner Strae 7 01737 Tharandt Germany Forestry and Wood Technology Discipline Khulna University Khulna Bangladesh

The concept of community resilience in the contexts of climate change and disasters draws increasing attention and interest from practitioners and researchers in recent development discourse. This paper provides a critical review of six selected frameworks of community resilience building operationalized in Bangladesh over the span of years. In other words, this study aims to contribute to the understanding of resilience through a systematic analysis of the dimensions and indicators of community resilience frameworks. The analysis shows that comprehensive and effective community resilience frameworks should incorporate the missing components linked to fundamental elements of good governance, economic growth, environmental sustainability, social transformation, and capacity development. The paper concludes by highlighting a few other areas of grave concern that need more appropriate attention, considering the severe threats posed by climate change and natural disasters in line with sustainable development goals. Finally, this study recommends further research regarding the effectiveness of these frameworks in different climatic and disaster contexts that can lead the concept into a new dimension of community resilience and sustainability.

关键词： Community Resilience Resilience Building Framework Resilience Indicators Climate Change Disaster Bangladesh

Multi-species probiotics enhance survival,growth,intestinal microbiota and disease resistance of rohu(Labeo rohita)larvae

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Water Biology and Security 2024年第1期3卷 71-79页

作者： Zannatul Ferdous md Kabir Hossain md Hadiuzzaman SMRafiquzzaman KM abdul Halim Tanvir Rahman md ali Reza Faruk Zulhisyam abdul Kari md Shahjahan Laboratory of Fish Ecophysiology Department of Fisheries ManagementBangladesh Agricultural UniversityMymensingh2202Bangladesh Department of Aquaculture Bangladesh Agricultural UniversityMymensingh2202Bangladesh Department of Fisheries Matshoy BhabanDhakaBangladesh Department of Fisheries Biology&Aquatic Environment Bangabandhu Sheikh Mujibur Rahman Agricultural UniversityGazipur1706Bangladesh Department of Agricultural Sciences Faculty of Agro-Based IndustryUniversiti Malaysia KelantanJeli Campus17600JeliKelantanMalaysia

Multi-strain probiotics provide the most dependable approaches to improve health,immune response,and disease resistance in farmed *** the present study,we examined the effects of multi-species probiotics on the survival,growth,immune response,and disease resistance of rohu(Labeo rohita)*** hatched larvae from the day of first feeding(average weight of 0.003 g)were reared with multi-species probiotics having a combination of Bacillus subtilis(109 colony forming units(cfu)/mL)and Lactobacillus spp.(Lactobacillus plantarum,Lactobacillus buchneri-1011 cfu/mL)in water containing doses of 0(control-C),0.5 mL/L(treatment 1-T1),and 1.0 mL/L(treatment 2-T2)in triplicates for 90 *** the experiment,a challenge test was performed to assess the fish's resistance to pathogenic Aeromonas *** higher survival was recorded in larvae of treated groups(87%in T2 and 79%in T1)compared to the control(62%).Significantly higher growth performance(weight gain and specific growth rate—SGR)was shown by the probiotic-treated larval groups compared to the *** supplementation resulted in significantly higher counts of total viable colony(TVC)and lactic acid bacteria(LAB)in the *** immunological parameters(mucosal fold fattening,goblet cell abundance,expansion of lamina propria and enterocytes)of the gut were significantly better in probiotic-treated *** liver of treated fish showed irregular shape nuclei turning into regular shape and reducing spaces between the hepatic ***-treated fish had the highest post-challenge survival rate(90%)against *** *** erythrocytes of challenged fish treated with probiotics had significantly lower frequencies of various nuclear and cellular *** findings suggest that multi-species probiotic supplements could improve the survival,growth,health status,and immune response of rohu in the early stages of its development.

关键词： Aquaculture Disease resistance Immunity Labeo rohita Probiotics

Graphene oxide-coated microbottle resonators for relative humidity sensing

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Optoelectronics Letters 2024年第7期20卷 400-405页

作者： Huda Adnan Zain Malathy Batumalay md Ashadi md Johari Hazli Rafis abdul Rahim Sulaiman Wadi Harun Department of Electrical Engineering Faculty of EngineeringUniversity of MalayaKuala Lumpur 50603Malaysia Faculty of Data Science and Information Technology INTI International UniversityNilai 71800Malaysia1 Faculty of Electrical and Electronic Engineering Technology Universiti Teknikal Malaysia MelakaMelaka 76100Malaysia Faculty of Electronic and Computer Engineering Universiti Teknikal Malaysia MelakaMelaka 76100Malaysia

Graphene oxide(GO)is a 2D coating material used to improve fiber optics sensors’response to relative *** resonators(MBRs)have garnered more attention as sensing media *** MBR with a 190μm diameter was coated with ***,tapered fiber light coupling was used to investigate the relative humidity sensing performance in the range of 35—70%RH at 25℃.The MBR showed a higher Q factor before and after GO *** sensitivity of 0.115 dB/%RH was recorded with the 190μm GO-coated MBR sample compared to a sensitivity of 0.022 dB/%RH for the uncoated MBR *** results show that the MBR can be used in fiber optic sensing applications for environmental sensing.

关键词： humidity oxide bottle