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High platelet distribution width can independently predict testicular survival in testicular torsion among patients with steady-state sickle cell anemia

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World Journal of Pediatric Surgery 2022年第1期5卷 12-17页

作者： Essa A Adawi mazen Ahmed ghanem Ahmed mazen ghanem Manal A Safan Mohamed G Elsayed Mohammed A Aqeel Urology Jazan UniversityJazanSaudi Arabia Urology Menoufia University Faculty of MedicineAI Rehab CityNew CairoEgypt GP Cairo University Kasr Alainy Faculty of MedicineAI Rehab CityNew CairoEgypt Department of Medical Biochemistry and Molecular Biology Menoufia University Faculty of MedicineAI Rehab CityNew CairoEgypt Pediatric Surgery Jazan UniversityJazanSaudi Arabia Department of Anesthesia and Critical Care Jazan UniversityJazanSaudi Arabia

Objective This study aimed to evaluate the predictive value of platelet volume indices(PVI),such as mean platelet volume(MPV),platelet distribution width(PDW),and plateletcrit(PCT),as prognostic indicators of testicular viability in torsion patients with steady-state sickle cell anemia(SCA)who underwent surgical *** Forty-eight patients with SCA with testicular torsion and 46 male control subjects were enrolled in the *** patients underwent scrotal color Doppler ultrasonography before surgery,and PVI(MPV,PDW,and PCT)values were measured in all *** duration and testicular volume were also *** The testicular salvage rate in patients with SCA was 73%after *** showed that MPV,PDW,and PCT values were significantly higher in torsed SCA as compared with controls(p<0.05).Orchiectomy in patients with SCA showed significantly higher MPV,PDW,and PCT values than the orchiopexy group(p<0.05).The MPV values of orchiectomy patients showed a higher significant cut-off of≥11.5 fL,which is higher than in torsed patients without SCA,as an indicator of testis *** also demonstrated a higher significant cut-off of≥12.7 fL for detorsion outcomes in patients with *** duration of less than 7 hours was also significantly correlated with orchiopexy(p≤0.001).Univariate analysis showed that higher MPV,increased PDW,and symptom duration were indicative of the outcome of testicular detorsion in *** analysis showed that increased PDW and symptom duration are prognostic parameters for testicular viability in *** Increased PDW and symptom duration can be used as parameters for predicting testicular detorsion outcomes in patients with steady-state SCA.

关键词： patients anemia torsion

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The role of varicocele sclerotherapy in men with severe ol igo-astheno-teratozoos perm ia

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Asian Journal of Andrology 2011年第6期13卷 867-871页

作者： mazen a ghanem Manal A Safan Ashraf A ghanem Gert R Dohle Department of Urology Menoufiya University 3481 Shebin EI-Kom Egypt Department of Urology Erasmus MC 3000 CA Rotterdam The Netherlands Department of Clinica Biochemistry Menoufiya University 3481 Shebin EI-Kom Egypt Department of Gynaecology and Obstetrics Mansoura University 35515 Mansoura Egypt

The aim of this study was to verify the role of antegrade scrotal sclerotherapy for the treatment of varicoceles in infertile men with severe oligo-astheno-teratozoospermia （OAT）. The 59 patients with severe OAT in this study underwent antegrade scrotal sclerotherapy for the treatment of varicoceles. The outcome was assessed in terms of improvement in semen parameters and spontaneous conception rate. Semen parameters and reproductive hormones were evaluated before antegrade sclerotherapy （AS） and 6 months after AS. After an average follow-up time of 34.8_＋3.2 months, significant improvement was noted in the mean sperm concentration, motility and morphology in 36 patients （61%）. Spontaneous pregnancy occurred in nine couples （15%）. Six months after treatment, inhibin B levels were significantly higher （P〉0.04）, whereas follicle-stimulating hormone （FSH） levels were significantly lower （P〈0.001） than before treatment. Antegrade internal spermatic vein sclerotherapy can significantly improve seminal parameters and hormonal parameters in men with severe OAT and may even result in spontaneous pregnancy in couples who would otherwise be candidates for intracytoplasmic sperm injection （ICSI）.

关键词： infertility Inhibin B oligo-astheno-teratozoospermia sclerotherapy semen parameters varicocele

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Deep Learning Based Efficient Crowd Counting System

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Computers, Materials & Continua 2024年第6期79卷 4001-4020页

作者： Waleed Khalid Al-ghanem Emad Ul Haq Qazi Muhammad Hamza Faheem Syed Shah Amanullah Quadri Department of Computer Engineering College of Computer and Information SciencesKing Saud UniversityRiyadh12372Saudi Arabia Centre of Excellence in Cybercrime and Digital Forensics Naif Arab University for Security SciencesRiyadh14812Saudi Arabia Center of Excellence for Information Assurance(COEIA) King Saud UniversityRiyadh12372Saudi Arabia

Estimation of crowd count is becoming crucial nowadays,as it can help in security surveillance,crowd monitoring,and management for different *** is challenging to determine the approximate crowd size from an image of the crowd’s *** in this research study,we proposed a multi-headed convolutional neural network architecture-based model for crowd counting,where we divided our proposed model into two main components:(i)the convolutional neural network,which extracts the feature across the whole image that is given to it as an input,and(ii)the multi-headed layers,which make it easier to evaluate density maps to estimate the number of people in the input image and determine their number in the *** employed the available public benchmark crowd-counting datasets UCF CC 50 and ShanghaiTech parts A and B for model training and testing to validate the model’s *** analyze the results,we used two metrics Mean Absolute Error(MAE)and Mean Square Error(MSE),and compared the results of the proposed systems with the state-of-art models of crowd *** results show the superiority of the proposed system.

关键词： Crowd counting EfficientNet multi-head attention convolutional neural network transfer learning

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Impact of metal polluted sewage water on soil nematode assemblages in agricultural settings of Aligarh,India

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Soil Ecology Letters 2024年第1期6卷 61-75页

作者： Mohammed F.S.A.ghanem Shahid Afzal Humira Nesar Zarrin Imran Wasim Ahmad Nematode Biodiversity Research Lab Department of ZoologyAligarh Muslim UniversityAligarh 202002India

Sewage water in agriculture threatens human health and soil ecosystems through metal *** show promise as bioindicators of soil health due to their abundance and position in soil food ***-polluted water decreased abundance of certain nematode groups and Sigma Maturity *** pollution positively affected nematode groups with r-selected life *** water has been inappropriately used in agriculture,posing possible threats to human health and the soil ecosystems by its constituent pollutants,especially heavy *** evaluation of its influences on soil biomes needs to consider the response of soil *** soil organisms,nematodes are seen as the best promising candidates for bioindicators of soil *** in,we collected soil samples from fresh water irrigated field from three sites(S1,S2 and S3)and sewage water irrigated distance gradient(5 m-40 m),to assess the influence of metal(Cu,Zn,Cd,Mn,Pb)polluted water on various characteristics of nematode *** results indicated that the heavy metals decreased the abundance of C-p3 nematodes,herbivores,and predatory nematodes as well as sigma maturity index,whereas,C-p1,C-p2,bacterivore and fungivore nematodes abundance and diversity positively responded to the metal ***,nematode genera with r-selected life cycle were positively affected and those with K-selected life cycle were negatively affected by metal *** nematode community has potential to be used as indicator of pollution stress in agricultural soils to check soil health and sustainability.

关键词： heavy metals sewage irigation agriculture nematodes bioindicators

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Climate Changes and Sustainability

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Open Journal of Ecology 2024年第1期14卷 17-53页

作者： Kholoud Z. ghanem Department of Biological Science College of Science & Humanities Shaqra University Riyadh Saudi Arabia

Climate change is the phrase used to describe long-term changes in temperatures and weather patterns. Changes in the atmosphere and their interactions with diverse geologic, chemical, biological, and geographic variables are the main contributors to this cyclical adjustment of the Earth’s climate. Such changes may be induced purposefully, because of burning fossil fuels, clearing forests, and raising animals, or they may be natural, brought on by significant volcanic eruptions or variations in the sun’s activity. By significantly increasing the amount of greenhouse gases already in the atmosphere, this heightens the greenhouse effect and contributes to global warming. This work includes several additional theoretical and practical explanations of sustainable development. The theoretical work encompasses hundreds of researches that identify requirements for how development routes might satisfy sustainable development (SD) criteria using economic theory, complex systems approach, ecological science, and other techniques. The agreements made by the Parties in various nations across the world will consider a wide range of perspectives about what would be considered undesirable effects on the environment, the climate system, sustainability, economic growth, or food production.

关键词： Earth System Ancient Climatic Changes Causes of Climatic Changes Ecological Risk Assessment Ecosystem Abrupt Climate Change of Earth Sustainability

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Management Practices of Locally Advanced and Metastatic Urothelial Carcinoma: A Questionnaire-Based Survey among Lebanese Oncologists

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Open Journal of Urology 2024年第2期14卷 138-149页

作者： Joseph Kattan Sally Temraz Fadi Nasr Arafat Tfayli Christina Khater Anas Mugharbel Hady ghanem Hampig Raphael Kourie Georges Hachem Sarah Masri Jamil Debs Ali Shamseddine Department of Hematology-Oncology H&#244tel-Dieu de France University Hospital Faculty of Medicine Saint-Joseph University of Beirut Beirut Lebanon Department of Internal Medicine Hematology-Oncology Division American University of Beirut Medical Center Beirut Lebanon Hematology-Oncology Division American University of Beirut Medical Center Beirut Lebanon Department of Hematology-Oncology Saint Charles Hospital Beirut Lebanon Department of Internal Medicine Makassed General Hospital Beirut Lebanon Hematology-Oncology Division Lebanese American University Medical Center - Rizk Hospital Beirut Lebanon Department of Hematology-Oncology Saint George Hospital University Medical Center Beirut Lebanon Pfizer Medical Affairs Beirut Lebanon

Background and Objective: The outcome of locally advanced and metastatic urothelial carcinoma LA/mUC has improved over the past years with a plethora of new treatments and the approval of immune checkpoint inhibitors (ICIs), antibody-drug conjugates, and targeted agents, to identify locally advanced metastatic urothelial carcinoma’s current management practices in Lebanon and the implication of the ongoing economic crisis on the medical practice. Methods: An online questionnaire was used to survey ten Lebanese oncologists from six different hospitals, between July 5 and July 11, 2022, requesting information pertaining to their current clinical practice in the pharmacological treatment of locally advanced metastatic urothelial carcinoma. Key Findings: Cisplatin-based chemotherapy was the most frequently reported initial treatment of locally advanced metastatic urothelial carcinoma. Participants reported using immune checkpoint inhibitors in platinum-ineligible patients and those with PDL1 positive tumors. Also, they would not consider the concomitant use of immunotherapy and chemotherapy in the first-line setting. Participants believed that avelumab maintenance is effective in the absence of progression after first-line platinum-based chemotherapy;they would consider initiating it 2 - 10 weeks after completion of chemotherapy. Conclusions and Clinical Implications: After comparing with current international guidelines, this study shows that Lebanese oncologists follow international guidelines and have deep knowledge of recent clinical trials for the management of locally advanced metastatic urothelial carcinoma, regardless of economic crisis challenges.

关键词： Clinical Practice Chemotherapy Immune Checkpoint Inhibitors PDL1 Urothelial Carcinoma

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A PRIORI ERROR ESTIMATES FOR OBSTACLE OPTIMAL CONTROL PROBLEM,WHERE THE OBSTACLE IS THE CONTROLITSELF

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Journal of Computational Mathematics 2023年第4期41卷 717-740页

作者： Yazid Dendani Radouen ghanem Numerical analysis optimisation and statistical laboratory(LANOS)Badji-MokhtarAnnaba UniversityP.O.Box 1223000Annaba Algeria

In this paper we deal with the convergence analysis of the finite element method for an elliptic penalized unilateral obstacle optimal control problem where the control and the obstacle *** estimates are established for both state and control *** apply a fixed point type iteration method to solve the discretized *** corroborate our error estimations and the eficiency of our algorithms,the convergence results and numerical experiments are illustrated by concrete examples.

关键词： Optimal control Obstacle problem Finite element A priori error estimate

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Occurrence and ecotoxicological risk assessment of pesticides in sediments of the Rosetta branch,Nile River, Egypt

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Journal of Environmental Sciences 2022年第8期34卷 21-31页

作者： Fawzy Eissa Mahmoud Al-Sisi Khaled ghanem Environment and Bio-agriculture Department Faculty of AgricultureAl-Azhar UniversityNasr CityCairo 11884Egypt Central Laboratory of Residue Analysis of Pesticides and Heavy Metals in Food(QCAP) Agricultural Research CenterDokkiGiza 12311Egypt

This study aimed to(1) monitor the occurrence and spatiotemporal variations of 100 pesticides in sediments collected monthly from July 2018 to June 2019 from sampling sites in El-Rahawy, Sabal, and Tala, along the Rosetta branch of the Nile River, Egypt, and(2) perform an ecological risk assessment for aquatic organisms upon exposure to the detected sediment pesticides based on the risk quotient(RQ) method. Out of the 100 pesticides monitored, 16 pesticides belonging to seven chemical families were detected, and 55% of the sediment samples were contaminated with one or more pesticide residues. The mean concentration(mg/kg dry weight(dw)) and detection frequency(%) of the four most frequently detected pesticides in the sediment samples were as follows: chlorpyrifos(0.18 mg/kg dw and 34%), p,p-DDE(0.018 mg/kg dw and 30%), cypermethrin(0.03 mg/kg dw and 14%), and deltamethrin(0.026 mg/kg dw and 13%). The spatial distribution exhibited that El-Rahawy had the highest pesticide load(2.86 mg/kg dw) among the studied sites, whereas the temporal variations revealed that the highest total pesticide concentrations were detected in winter season(1.73 mg/kg dw). Meanwhile, 12 pesticides showed high RQs(>1), posing a potential ecological risk to aquatic species that live and feed on such sediments.

关键词： Pesticide residues Sediments Spatiotemporal variations Risk quotient

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E-mail Spam Classification Using Grasshopper Optimization Algorithm and Neural Networks

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Computers, Materials & Continua 2022年第6期71卷 4749-4766页

作者： Sanaa A.A.Ghaleb Mumtazimah Mohamad Syed Abdullah Fadzli Waheed A.H.M.ghanem Faculty of Informatics and Computing Universiti Sultan Zainal AbidinKuala Terengganu22200Malaysia Faculty of Ocean Engineering Technology and Informatics Universiti Malaysia TerengganuKuala Terengganu21030Malaysia Faculty of Engineering University of AdenAdenYemen Faculty of Education(Aden-Saber) University of AdenAdenYemen

Spam has turned into a big predicament these days,due to the increase in the number of spam emails,as the recipient regularly receives piles of *** only is spam wasting users’time and *** addition,it limits the storage space of the email box as well as the disk ***,spam detection is a challenge for individuals and organizations *** advance spam email detection,this work proposes a new spam detection approach,using the grasshopper optimization algorithm(GOA)in training a multilayer perceptron(MLP)classifier for categorizing emails as ham and ***,MLP and GOA produce an artificial neural network(ANN)model,referred to(GOAMLP).Two corpora are applied Spam Base and UK-2011Web spam for this ***,the finding represents evidence that the proposed spam detection approach has achieved a better level in spam detection than the status of the art.

关键词： Grasshopper optimization algorithm multilayer perceptron artificial neural network spam detection approach

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Application of microalgal-ZnO-NPs for reusing polyester/cotton blended fabric wastes after modification by cellulases enzymes

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Waste Disposal and Sustainable Energy 2023年第4期5卷 471-482页

作者： Osama M.Darwesh Naser G.Al-Balakocy Ahmed ghanem Ibrahim A.Matter Agricultural Microbiology Department National Research Centre33 EL-Buhouth St.DokkiCairo12622Egypt Protenic and Manmade Fibers Department National Research CentreDokkiCairo12622Egypt Packaging Materials Department National Research CentreCairo12622Egypt

Polyester/cotton(PET/C)blended fabric wastes are produced daily in huge amounts,which constitutes an economic loss and an environmental threat if it is not reused *** textile waste recycling technologies put much effort into developing fabric materials with unique properties,such as bioactivity or new optical goods based on modern technologies,especially *** this study,zinc oxide nanoparticles(ZnO-NPs)were biosynthesized using the aqueous extract of Dunaliella *** immobilized on PET/C waste fabrics after enzymatically activated with *** produced Dunaliella-ZnO-NPs(10–20 nm with a spherical shape)were characterized by High-resolution transmission electron microscopy(HRTEM),Fourier-transform infrared spectroscopy(FTIR),X-Ray diffraction analysis(XRD),and Scanning electron microscopy-energy dispersive X-ray analyzer(SEM-EDAX),and some functional groups,such as CH,CO,NH,and CN(due to the presence of carboxyl,proteins and hydroxyl groups),were detected,revealing the biosynthesis of *** analysis showed that the resulting ZnO-NPS had potent antimicrobial effects,Ultraviolet(UV)protection capabilities,and no cytotoxic effects on the normal human fibroblast cell line(BJ1).On the other hand,enzymatic treatments of PET/C fabric waste with cellulases enhanced the immobilization of biosynthetic nanoparticles on their *** PET/C fabrics loaded with Dunaliella-ZnO-NPs showed antibacterial and UV protection capabilities making them an eco-friendly and cost-effective candidate for numerous *** applications can include the manufacture of active packaging devices,wastewater treatment units,and many other environmental applications.

关键词： Wastewater remediation Polyester/cotton wastes Cytotoxicity Microalgal-ZnO-NPs Dunaliella sp. Microbial nanotechnology

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