The role of varicocele sclerotherapy in men with severe ol igo-astheno-teratozoos perm ia

作     者：Mazen A Ghanem Manal A Safan Ashraf A Ghanem Gert R Dohle 

作者机构：Department of Urology Menoufiya University 3481 Shebin EI-Kom Egypt Department of Urology Erasmus MC 3000 CA Rotterdam The Netherlands Department of Clinica Biochemistry Menoufiya University 3481 Shebin EI-Kom Egypt Department of Gynaecology and Obstetrics Mansoura University 35515 Mansoura Egypt 

出 版 物：《Asian Journal of Andrology》 (亚洲男性学杂志（英文版）)

年 卷 期：2011年第13卷第6期

页      面：867-871页

核心收录：

学科分类：07[理学] 0905[农学-畜牧学] 08[工学] 070206[理学-声学] 09[农学] 0802[工学-机械工程] 090501[农学-动物遗传育种与繁殖] 0702[理学-物理学] 

主　　题：infertility Inhibin B oligo-astheno-teratozoospermia sclerotherapy semen parameters varicocele 

摘      要：The aim of this study was to verify the role of antegrade scrotal sclerotherapy for the treatment of varicoceles in infertile men with severe oligo-astheno-teratozoospermia （OAT）. The 59 patients with severe OAT in this study underwent antegrade scrotal sclerotherapy for the treatment of varicoceles. The outcome was assessed in terms of improvement in semen parameters and spontaneous conception rate. Semen parameters and reproductive hormones were evaluated before antegrade sclerotherapy （AS） and 6 months after AS. After an average follow-up time of 34.8_＋3.2 months, significant improvement was noted in the mean sperm concentration, motility and morphology in 36 patients （61%）. Spontaneous pregnancy occurred in nine couples （15%）. Six months after treatment, inhibin B levels were significantly higher （P〉0.04）, whereas follicle-stimulating hormone （FSH） levels were significantly lower （P〈0.001） than before treatment. Antegrade internal spermatic vein sclerotherapy can significantly improve seminal parameters and hormonal parameters in men with severe OAT and may even result in spontaneous pregnancy in couples who would otherwise be candidates for intracytoplasmic sperm injection （ICSI）.