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Success rates and predictors of outcomes of type I tympanoplasty performed by residents in a teaching tertiary hospital

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Journal of Otology 2023年第4期18卷 214-219页

作者： Lucas Resende Lucinda Mangia Nicole Tassia Amadeu maurício da Silva oliveira Lucas Santin Patzer Eduardo de Souza Somensi Rogerio Hamerschmidt department of Otolaryngology and Head and Neck Surgery Complexo Hospital de Clínicas-Universidade Federal Do Parana(CHC-UFPR)CuritibaBrazil Complexo Hospital de Clínicas-Universidade Federal Do Parana(CHC-UFPR) Curso de MedicinaCuritibaBrazil

Several technical variations of tympanoplasty have been reported,usually involving the type of graft and/or instruments *** studies have focused on the outcome of type-1 tympanoplasty specifically in teaching *** aimed to describe the results of type-1 tympanoplasty performed by residents,and to investigate potential predictive factors of surgical *** do so,we did a retrospective analysis of medical records of patients who underwent type-1 tympanoplasty in a tertiary university *** evaluated the tympanic membrane closure and audiometric outcomes during the first year of follow-up,and compared the results according to some clinical and surgical factors.130 operated ears were included in the *** closure rate reached 84.12%after one month and 72.72%after twelve months of *** mean air-bone gap was 22.98 dB preoperatively,and reached 10.55 dB after *** closure rates were 85%and 57.14%for those operated by endoscopic and microscopic-assisted approaches,respectively(p?0.004).The use of cartilage grafts and time without otorrhea of more than three months prior to surgery were also predictors of surgical success(p?0.002 and 0.041,respectively).Gender,age,perforation size,contralateral disease,operated side,reoperation,and degree of hearing loss did not significantly interfere with *** showed good overall results when performed by residents,although inferior to those reported by experienced *** use of the endoscope,cartilage grafting,and longer preoperative time without otorrhea were predictors of surgical success in this scenario.

关键词： Tympanoplasty Treatment outcome Video-assisted surgery

Selection signatures in Canchim beef cattle

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Journal of Animal Science and Biotechnology 2017年第1期8卷 15-23页

作者： Ismael Urbinati Nedenia Bonvino Stafuzza Marcos Túlio oliveira Tatiane Cristina Seleguim Chud Roberto Hiroshi Higa Luciana Correia de Almeida Regitano maurício Mello de Alencar Marcos Eli Buzanskas Danísio Prado Munari departamento de Ciencias Exatas Univ Estadual PaulistaFaculdade de Ciencias Agrairias e VeterinairiasjaboticabalSao Paulo 14884-900Brazil departamento de Tecnologia UNESP-Univ Estadual PaulistaFaculdade de Ciencias Agrarias e VeterinariasJaboticabalSao Paulo 14884-900Brazil Embrapa Agricultural Informatics CampinasSao Paulo 13083-886Brazil Embrapa Southeast Livestock Sao CarlosSao Paulo 13560-970Brazil

Background： Recent technological advances in genomics have allowed the genotyping of cattle through single nucleotide polymorphism（SNP） panels. High-density SNP panels possess greater genome coverage and are useful for the identification of conserved regions of the genome due to selection, known as selection signatures（SS）. The SS are detectable by different methods, such as the extended haplotype homozygosity（EHH）; and the integrated haplotype score（i HS）, which is derived from the EHH. The aim of this study was to identify SS regions in Canchim cattle（composite breed）, genotyped with high-density SNP ***： A total of 687,655 SNP markers and 396 samples remained for SS analysis after the genotype quality control. The i HS statistic for each marker was transformed into pi HS for better interpretation of the *** BTA5 and BTA14 showed pi HS 〉 5, with 39 and nine statistically significant SNPs（P 〈 0.00001）,respectively. For the candidate selection regions, i HS values were computed across the genome and averaged within non-overlapping windows of 500 Kb. We have identified genes that play an important role in metabolism,melanin biosynthesis（pigmentation）, and embryonic and bone ***： The observation of SS indicates that the selection processes performed in Canchim, as well as in the founder breeds（i.e. Charolais）, are maintaining specific genomic regions, particularly on BTA5 and BTA14. These selection signatures regions could be associated with Canchim characterization.

关键词： Composite breed Extended haplotype homozygosity Genomics Single nucleotide polymorphism

Pathogenesis and clinical management of arboviral diseases

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World Journal of Virology 2025年第1期14卷 9-50页

作者： Victoria Cenci Dietrich Juan Marcos Caram Costa Marina Maria Gomes Leite oliveira Carlos Eduardo oliveira Aguiar Luis Guilherme de oliveira Silva Marcel Silva Luz Fabian Fellipe Bueno Lemos Fabrício Freire de Melo Instituto Multidisciplinar em Saúde Universidade Federal da BahiaVitória da Conquista 45029-094BahiaBrazil

Arboviral diseases are viral infections transmitted to humans through the bites of arthropods,such as mosquitoes,often causing a variety of pathologies associated with high levels of morbidity and *** the past decades,these infections have proven to be a significant challenge to health systems worldwide,particularly following the considerable geographic expansion of the dengue virus(deNV)and its most recent outbreak in Latin America as well as the difficult-tocontrol outbreaks of yellow fever virus(YFV),chikungunya virus(CHIKV),and Zika virus(ZIKV),leaving behind a substantial portion of the population with complications related to these ***,the world is experiencing a period of intense globalization,which,combined with global warming,directly contributes to wider dissemination of arbovirus vectors across the ***,all continents remain on high alert for potential new ***,this review aims to provide a comprehensive understanding of the pathogenesis of the four main arboviruses today(deNV,ZIKV,YFV,and CHIKV)discussing their viral characteristics,immune responses,and mechanisms of viral evasion,as well as important clinical aspects for patient *** includes associated symptoms,laboratory tests,treatments,existing or developing vaccines and the main associated complications,thus integrating a broad historical,scientific and clinical approach.

关键词： Arboviruses Arbovirus infections dengue Zika virus Yellow fever Chikungunya virus Clinical diagnosis Pathogenesis Flavivirus Togaviridae infections

Light intensity and hydrogel soil amendment differentially affect growth and photosynthesis of successional tree species

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Journal of Forestry Research 2023年第1期34卷 257-268页

作者： Léo Vieira Leonel Fabrício de oliveira Reis Fábio Afonso Mazzei Moura de Assis Figueiredo Tiago Massi Ferraz Sebastiao de oliveira Maia Júnior Patrick Costa Silva Jailma Ribeiro de Andrade Graduate Program in Agroecology State University of MaranhaoAv.Lourenco Vieira da Silva1000Jardim Sao CristovaoSao LuísMaranhao 65055-310Brazil State University of Maranhao Av.Lourenco Vieira da Silva1000Jardim Sao CristovaoSao LuísMaranhao 65055-310Brazil Graduate Program in Agriculture and Environment State University of MaranhaoPraca Goncalves Diass/nCentroBalsasMaranhao 65800-000Brazil

Global climate changes have increased temperatures,radiation indexes,and consequently,irregularities in rainfall in mainly tropical countries,considerably hindering plant establishment in recovering degraded *** objective of this study was to evaluate the growth and physiological characteristics of one species of each successional group:pioneer,secondary,and climax when subjected to different light intensities and hydrogel as a soil conditioner during rainy and dry *** experiment was conducted in the ecotone between Brazil’s two largest biomes,the Cerrado and the Amazon in the State of Maranh?*** parameters consisted of three species:Guazuma ulmifolia Lam.(pioneer),Astronium fraxinifolium Schott(secondary),and Cariniana rubra Gardner ex Miers(climax).There were two light intensities:70%and 100%,and two planting conditions:with and without soil conditioner(hydrogel).Gas exchanges were higher during the rainy season;the pioneer and secondary species had greater heights and photosynthetic rates in the dry period;the climax species had the lowest gas exchange and lowest recovery as rainfall *** pioneer and secondary species showed higher physiological plasticity,denoting better adaption to environments with high *** improved the photosynthetic performance of these species in the dry season and in areas with 100%sunlight.

关键词： Irradiance Hydrogel Photosynthetic efficiency Physiological plasticity

Production and quality of eucalyptus mini-cuttings using kaolin-based particle films

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Journal of Forestry Research 2021年第3期32卷 953-965页

作者： Maria de Fátima de Castro oliveira Diego Pereira Santos Karolline Sena Figueredo Fabrício de oliveira Reis Tiago Massi Ferraz Heder Braun Eliemar Campostrini Fábio Afonso Mazzei Moura de Assis Figueiredo Graduate Program in Agriculture and Environment Centro de Estudos Superiores de BalsasState University of MaranhaoPraca Goncalves Diass/nCentro65800-000 BalsasMABrazil Enraize-E.M.Figueredo Ind.e Com.de Produtos Florestais Br 222Km 09Lote 52Margem Esquerda S/n:Chac.Belo HorizonteZona RualAcailandiaMABrazil Centro de Ciências Agrárias State University of MaranhaoAv.Lourenco Vieira da Silva1000Jardim Sao Cristovao65055-310 Sao LuísMABrazil CCTA Northern Rio de Janeiro State UniversityAv.Alberto Lamego200028013-602 Campos dos GoytacazesRJBrazil

Considering the expansion of forest plantations over the Brazilian territory and the imminent increase in air temperatures due to global warming,the search for technologies that ensure high levels of productivity and high quality plants in clonal nurseries is *** kaolin-based particle films(KBPF)has been used as a physical barrier to reduce the negative effects of excessive solar radiation and adverse *** effects of KBPF on production and physiological quality of eucalyptus mini-cuttings were evaluated during two different seasons.A randomized block design was used,consisting of five treatments and four *** concentrations(0,3%,5%,7%,and 10%)were tested here and six weekly replicates of each concentration was *** different kaolin concentrations and seasonal variations resulted in a quadratic response of the leaf SPAD reading during both daily evaluation *** applications resulted in a quadratic response of photochemical efficiency in the morning period,and an increasing specific leaf weight linear response,and during the dry season,the different kaolin concentrations resulted in a bud length quadratic *** results indicated that the kaolin application maintained the production and yield index statistically equal between weekly KBPF applications,improving photochemical efficiency,leaf thickness,SPAD reading,and bud *** use of KBPF could reduce the intervals between collections of mini-cuttings and increase nursery yields in environments that present high temperatures.

关键词： Photoprotector Ecophysiology Forestry Clonal propagation

Human occupation explains species invasion better than biotic stability:evaluating Artocarpus heterophyllus Lam.(Moraceae;jackfruit)invasion in the Neotropics

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Journal of Plant Ecology 2018年第3期11卷 465-474页

作者： Guilherme de oliveira Laboratório de Biogeografia da Conservação Universidade Federal do Recôncavo da Bahia(UFRB)Centro de Ciências AgráriasAmbientais e Biológicas(CCAAB)Setor de Ciências BiológicasRua Rui Barbosa 710Centro 44380-000Cruz das AlmasBahiaBrasil

Aims Biological invasions are recognized to put native species in risk of *** this study,I tested whether the invasion of Artocarpus heterophyllus Lam.(Moraceae;jackfruit)in the Neotropics was explained by its biotic stability,an intrinsic force,or by human occupation,an extrinsic *** I used an ensemble framework combining 12 ecological niche models(ENMs)and 4 atmosphere-ocean general circulation *** were constructed for the pre-industrial time period in the Indo-Malaya biogeographic region,the native habitat of ***,and were then projected to past(last glacial maximum,21000 years ago and mid-Holocene,6000 years ago)and future(end of century,2080)*** ENMs were used to establish the biotic stability of ***-phyllus in areas where it was predicted to be present concomitantly within these four time *** biotic stability was projected onto the Neotropics,and then I used a null model and logistic regression to test what the main driver of *** *** Findings In general,the presence of *** in the Neotropics was not explained by biotic stability,tested by the null ***,human occupation explained much of its presence in the invaded habitat,once all standardized coefficients related to this driver was significant positive in the logistic *** on these results,humans sustained the presence of ***-erophyllus in the Neotropics,probably because of the additive influences of propagule pressure and habitat ***,the recommendation is that the cultivation of *** in the Neotropics must be regulated and supervised,primarily near reserve areas.

关键词： ecological niche models(ENMs) ensemble forecasting climate change habitat disturbance propagule pressure

Streptococcus agalactiae:Identification methods,antimicrobial susceptibility, and resistance genes in pregnant women

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World Journal of Clinical Cases 2020年第18期8卷 3988-3998页

作者： Fabrícia Almeida Fernandes Santana Tais Viana Ledo de oliveira Marcelo Barreto de Souza Filho Lucas Santana Coelho da Silva Breno Bittencourt de Brito Fabrício Freire de Melo Cláudio Lima Souza Lucas Miranda Marques Márcio Vasconcelos oliveira Instituto Multidisciplinar em Saúde Universidade Federal da BahiaVitória da Conquista 45029-094BahiaBrazil Laboratório oliveira Ltda LABOVitória da Conquista 45020740BahiaBrazil Campus Soane Nazaréde Andrade Universidade Estadual de Santa CruzIlhéus 45662900BahiaBrazil

BACKGROUND Group B Streptococcus(GBS)is a normal component of the gastrointestinal and genital microbiota in humans and can lead to important infections in *** To compare GBS isolation and identification methods as well as to assess the antibiotic susceptibility and to identify resistance genes in GBS strains from pregnant women attended in healthcare services from the city of Vitória da Conquista,in Bahia State,*** From January 2017 to February 2018,vaginorectal swabs were obtained from 186 participants and the samples were seeded onto chromogenic agar for GBS before and after inoculation in selective *** identification using 3 CAMP and latex tests was performed in samples with GBS-suggestive ***,disk diffusion antibiograms were performed in GBS-positive samples,and the detection of the resistance genes ermB,ermTR,mefA,and linB in the clindamycin and/or erythromycin-resistant samples was carried *** Thirty-two samples(17.2%)were *** culture in chromogenic agar after sample incubation in selective broth was the most sensitive method(96.9%)for GBS *** isolates were susceptible to penicillin,ampicillin,cefotaxime,and *** resistance was observed in 6 samples(18.8%),while 8 samples(25%)were *** erythromycin and/or clindamycin-resistant GBS strains had negative *** strains(25%)presented an M phenotype and 6 isolates(75%)presented a cMLSB *** ermB gene was identified in 4 samples(44.4%),the mefA gene was also found in 4 samples(44.4%),the ermTR gene was identified in 1 isolate(11.1%),and the linB gene was not found in any *** This study evidenced that the screening for SGB can be performed by means of various methods,including chromogenic media,and that the chemoprophylaxis for pregnant women who cannot use penicillin must be susceptibility-guided.

关键词： Streptococcus agalactiae Pregnancy Antimicrobial susceptibility

Physiological plasticity in eucalyptus clones in the vegetative stage contributes to drought tolerance

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Journal of Forestry Research 2023年第5期34卷 1549-1561页

作者： Vilma Marques Ferreira Jailma Ribeiro de Andrade Claudiana Moura dos Santos Sebastiao de oliveira Maia Júnior Joao Correia de Araújo Neto Andrea Francisca da Silva Santos Vicente Mota da Silva Lucas Teles Bezerra Laurício Endres Laboratório de Fisiologia Vegetal Campus de Engenharia e Ciências AgráriasUniversidade Federal de AlagoasRio LargoAL57072-900Brazil Laboratório de Ciências Ambientais e Biodiversidade Departamento de Zootecnia.Centro de Ciências AgráriasUniversidade Estadual do MaranhãoSão LuísMA65300-000Brazil Laboratório de Propagação de Plantas.Campus de Engenharia e Ciências Agrárias Universidade Federal de AlagoasRio LargoAL57072-900Brazil Laboratório de Lepidoptera Museu de ZoologiaUniversidade de São PauloIpirangaSão PauloSP04263-000Brazil

With the expansion of eucalyptus crops to areas with severe water limitations,physiological studies involving eucalyptus clones to identify those that are tolerant to water stress become *** objective of this study was to assess morphological and physiological responses by eucalyptus clones subjected to drought stress and *** experiment consisted of three eucalyptus clones:VC865,I224 and I144 and two water regimes:control and water stress followed by rehydration,with six *** water potential,gas exchange,maximum quantum efficiency of photo systemⅡand plant height and stem diameter were evaluated under drought stress and ***6 d of rehydration,the number of leaves,leaf area and dry mass of root,leaf,stem and their total were *** clones showed intense reduction of gas exchange during the drought stress period,and only VC865 and 1144 showed rapid recovery with 3 d of *** 1224 showed greater reduction in height,stem diameter,number of leaves,water potential at midday(Ψ_(w)_(Midday)),and maximum quantum efficiency of photosystemⅡ(F_(v)/F_(m)).Clones VC865and T144 showed lower reductions inΨ_(wMidday)and F_(v)/F_(m) under ***865 had lower reductions in leaf number,leaf area and higher leaf dry mass,while clone I144 had higher height and lower reduction in root dry mass *** these clones showed higher water use efficiency with 3d of *** different phenotypic plasticities gave the clones VC865 and 1144 efficient mechanisms of acclimatization to stress and more drought tolerance,enhancing their greater capacity for recovery after stress,which allowed lower dry mass *** 1224,however,was more susceptible to drought stress,undergoing greater physiological damage with only partial recovery during rehydration.

关键词： Drought Eucalyptus species Gas exchanges Post-stress Root dry mass

Assessment of alterability of basalt used for riprap by petrographic examination

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Journal of Rock Mechanics and Geotechnical Engineering 2019年第1期11卷 208-213页

作者： Maria Heloisa Barros de oliveira Frascá MHB Geological Services

All engineering projects consist of several steps, and one of the main tasks is to identify and characterize the most important features of rock types that will be excavated, crushed, or mined for any particular usage purpose, from a single residential building to major works of infrastructure. Laboratory investigation on engineering geology is thus conducted in order to determine the most relevant rock properties when designing structures such as mining shafts, tunnels, buildings, or reservoir dams to be built in sites associated with rocks. A wide range of laboratory tests is available, making the correct choice of test methods greatly relevant to determine the key property for the planned use of the rock. This paper is an illustrative case of laboratory testing of basaltic rocks to be used as riprap in a reservoir dam. It shows the important role of the petrographic study carried out to analyze the distribution pattern of smectite clay minerals. Test results are explained for the assessment of rock alterability, an essential aspect for the selection of the most suitable basalt variety for the envisaged conditions of use.

关键词： Rock properties Laboratory testing Test methods Petrographic analysis Smectite clay minerals Basaltic rocks Accelerated weathering tests Alterability