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Jour.al of Biophysical Chemistr. 2014年第3期5卷 91-98页

作者： r.bindr. N. r.y Lakshmi N. r.y John J. Dinga matthew r. medcalf Kather.ne E. Hundley Er.c B. Hines r.an r. Par.ar.Jamie A. Veliz Clar. B. Summer. Lucas S. Tebbe Hoffman Depar.ment of Chemistr. Drury University Springfield USA

Values of the second ther.odynamic dissociation constant pK2 of the pr.tonated for. of monosodium 1,4-piper.zinediethanesulfonate (PIPES) have been deter.ined at twelve differ.nt temper.tur.s in the temper.tur. r.nge fr.m (278.15 to 328.15) K including the body temper.tur. 310.15 K by measur.ment of the electr.motive-for.e for.cells without liquid junction of the type: Pt (s), H2 (g), 101.325 kPa|Na-PIPES (m1) + Na 2-PIPES (m2) + NaCl (m3)|AgCl (s), Ag (s), wher. m1, m2 and m3 indicate the molalities of the cor.esponding species at 1 atm = 101.325 kPa in SI units. The pK2 values for.the dissociation of Na-PIPES ar. r.pr.sented by the equation: pK2 = -1303.76/T + 48.369 - 6.46889 lnT with an uncer.ainty of ± 0.001. The values of pK2 for.Na-PIPES wer. found to be 7.1399 ± 0.0004 at 298.15 K and 7.0512 ± 0.0004 at 310.15 K, r.spectively, and indicate that this buffer.would be useful as pH standar. in the r.nge of physiological application. Standar. ther.odynamic quantities for.the acidic dissociation pr.cess of Na-PIPES have been der.ved fr.m the temper.tur. coefficients of the pK2. These values ar. compar.d with those of str.ctur.lly r.lated N-substituted PIPEr.ZINE and TAUr.NE at 298.15 K.

关键词： Dissociation Constant Zwitter.on Ionic Str.ngth pK2 Buffer Compound e.m.f Ther.odynamic Quantities

Scalable Ir.Doped NiFe₂O₄/TiO₂ Heter.junction Anode for.Decentr.lized Saline Wastewater.Tr.atment and H₂ Pr.duction

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NANO-MICr. LETTEr. 2025年第1期17卷 1-18页

作者： Hong, Sukhwa Kim, Jiseon Par., Jaebeom Im, Sunmi Hoffmann, Michael r. Cho, Kangwoo Pohang Univ Sci & Technol POSTECH Div Environm Sci & Engn Pohang 790784 South Korea CALTECH Linde Labs Pasadena CA 91125 USA Yonsei Univ Int Campus Inst Convergence Res & Educ Adv Technol I CREATE Incheon 21983 South Korea

Wastewater.electr.lysis cells (WECs) for.decentr.lized wastewater.tr.atment/r.use coupled with H-2 pr.duction can r.duce the car.on footpr.nt associated with tr.nspor.ation of water. waste, and ener.y car.ier. This study r.por.s Ir.doped NiFe2O4 (NFI, similar.to 5 at% Ir. spinel layer.with TiO2 over.ayer.(NFI/TiO2), as a scalable heter.junction anode for.dir.ct electr.lysis of wastewater.with cir.umneutr.l pH in a single-compar.ment cell. In dilute (0.1 M) NaCl solutions, the NFI/TiO2 mar.s super.or.activity and selectivity for.chlor.ne evolution r.action, outper.or.ing the benchmar. Ir.2. r.bust oper.tion in near.neutr.l pH was confir.ed. Electr.analyses including oper.ndo X-r.y absor.tion spectr.scopy unveiled cr.cial r.les of TiO2 which ser.es both as the pr.mar. site for.Cl- chemisor.tion and a pr.tective layer.for.NFI as an ohmic contact. Galvanostatic electr.lysis of NH4+-laden synthetic wastewater.demonstr.ted that NFI/TiO2 not only achieves quasi-stoichiometr.c NH4+-to-N-2 conver.ion, but also enhances H-2 gener.tion efficiency with minimal competing r.actions such as r.duction of dissolved oxygen and r.active chlor.ne. The scaled-up WEC with NFI/TiO2 was demonstr.ted for.electr.lysis of toilet wastewater.

关键词： Wastewater.electr.lysis cell Ir.doped NiFe2O4 r.active chlor.ne species Decentr.lized H-2 pr.duction On-site wastewater.tr.atment

Apples to or.nges:envir.nmentally der.ved,dynamic r.gulation of ser.tonin neur.n subpopulations in adulthood?

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Neur.l r.gener.tion r.sear.h 2025年第9期20卷 2596-2597页

作者： Chr.stopher.J.O’Connell matthew J.r.bson Depar.ment of Genetics College of MedicineHarvard UniversityBostonMAUSA James L.Winkle College of Phar.acy Division of Pharmaceutical SciencesUniversity of CincinnatiCincinnatiOHUSA Neur.science Gr.duate Pr.gr.m College of MedicineUniversity of CincinnatiCincinnatiOHUSA

Tr.umatic br.in injur.(TBI)is a public health pr.blem with an undue economic bur.en that impacts near.y ever. age,ethnic,and gender.gr.up acr.ss the globe(Capizzi et al.,2020).TBIs ar. often sustained dur.ng a dynamic r.nge of exposur.s to ener.etic envir.nmental for.es and as such outcomes ar. typically heter.geneous r.gar.ing sever.ty and pathology(Capizzi et al.,2020).

关键词： sustained or.nge dynamic

Exper.mental study of the r.stor.ng for.e mechanism in the self-center.ng beam （SCB）

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Fr.ntier. of Str.ctur.l and Civil Engineer.ng 2016年第3期10卷 272-282页

作者： Abhilasha MAUr.A matthew r. EATHEr.ON Depar.ment of Civil and Envir.nmental Engineer.ng Virginia Tech Blacksburg VA 2406 USA

In the past, sever.l self-center.ng （SC） seismic systems have been developed. However. examples of selfcenter.ng systems used in pr.ctice ar. limited due to unusual field constr.ction pr.ctices, high initial cost pr.miums and defor.ation incompatibility with the gr.vity fr.ming. A self center.ng beam moment fr.me （SCB-MF） has been developed that mitigates sever.l of these issues while adding to the advantages of a typical SC system. The self-center.ng beam （SCB） is a shop-fabr.cated, self-contained str.ctur.l component that when implemented in a moment r.sisting fr.me can br.ng a building back to plumb after.an ear.hquake. This paper.descr.bes the SCB concepts and exper.mental pr.gr.m on five SCB specimens at two-thir. scale r.lative to a pr.totype building. Exper.mental r.sults ar. pr.sented including the global for.e-defor.ation behavior. The SCBs ar. shown to under.o 5%-6% stor. dr.ft without any obser.able damage to the SCB body and columns. Str.ngth equations developed for.the SCB pr.dict the moment capacity well, with a mean differ.nce of 6% between exper.mental and pr.dicted capacities. The behavior.of the r.stor.ng for.e mechanism is descr.bed. The limit states that cause a loss in system＇s r.stor.ng for.e which lead to a decr.ase in the selfcenter.ng capacity of the SCB-MF, ar. pr.sented.

关键词： self-center.ng seismic system seismic design hyster.tic behavior r.stor.ng for.e r.silient str.ctur.l system

Complement-dependent neur.inflammation in spinal cor. injur.:fr.m pathology to ther.peutic implications

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Neur.l r.gener.tion r.sear.h 2025年第5期20卷 1324-1335页

作者： Hassan Saad Bachar.El Baba Ali Tfaily Fir.s Kobeissy Juanmar.o Gutier.ez Gonzalez Daniel r.fai Ger.ld r.r.dts Chr.stian Mustr.ph David Gimbel Jonathan Gr.ssber. Daniel L.Bar.ow matthew F.Gar. Ali M.Alawieh Depar.ment of Neur.sur.er. Emory University School of MedicineAtlantaGAUSA Depar.ment of Neur.logy Yale UniversityNew HavenCTUSA Center.for.Neur.tr.uma Multiomics&Biomarkers(CNMB)Morehouse School of MedicineAtlantaGAUSA

Spinal cor. injur. r.mains a major.cause of disability in young adults,and beyond acute decompr.ssion and r.habilitation,ther. ar. no phar.acological tr.atments to limit the pr.gr.ssion of injur. and optimize r.cover. in this *** the thor.ugh investigation of the complement system in tr.gger.ng and pr.pagating cer.br.l neur.inflammation,a similar.r.le for.complement in spinal neur.inflammation is a focus of ongoing *** this wor.,we sur.ey the cur.ent liter.tur. investigating the r.le of complement in spinal cor. injur. including the sour.es of complement pr.teins,tr.gger. of complement activation,and r.le of effector.functions in the *** study r.levant data demonstr.ting the differ.nt tr.gger. of complement activation after.spinal cor. injur. including dir.ct binding to cellular.debr.s,and or.activation via antibody binding to damage-associated molecular.*** effector.functions of complement have been implicated in spinal cor. injur.,and we cr.tically evaluate r.cent studies on the dual r.le of complement anaphylatoxins in spinal cor. injur. while emphasizing the lack of pathophysiological under.tanding of the r.le of opsonins in spinal cor. *** this pathophysiological r.view,we systematically r.view the differ.nt tr.nslational appr.aches used in pr.clinical models of spinal cor. injur. and discuss the challenges for.futur. tr.nslation into human *** r.view emphasizes the need for.futur. studies to dissect the r.les of differ.nt complement pathways in the pathology of spinal cor. injur.,to evaluate the phases of involvement of opsonins and anaphylatoxins,and to study the r.le of complement in white matter.degener.tion and r.gener.tion using tr.nslational str.tegies to supplement genetic models.

关键词： complement neur.inflammation neur.plasticity r.gener.tion spinal cor. injur. tar.eted ther.py

Special issue on quantum contr.l Dedicated to the occasion of Pr.f. lan Peter.en＇s 60th bir.hday

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Contr.l Theor. and Technology 2017年第3期15卷 161-162页

作者： Daoyi Dong Shanon Vuglar.matthew r. James School of Engineer.ng and Infor.ation Technology University of New South Wales Canberra Australia Guodong Shi Research School of Engineering Australian National University Australia Depar.ment of Chemistr. Princeton University U.S.A. Ar. Centr. for.Quantum Computation and Communication Technology Research School of Engineering Australian National University Australia

Quantum technology is r.cognized as one of the most pr.mising dir.ctions for.our.futur. technologies. By exploiting the unique featur.s of quantum effects, emer.ing quantum technology is r.pidly pr.gr.ssing ar.und the wor.d including quantum computation, quantum communication, quantum metr.logy and quantum simulation. The development of quantum contr.l plays a gr.unding r.le in enabling the pr.ser.ation and manipulation of quantum states that ar. used in var.ous quantum technologies. This special issue will focus on new development in r.levant topics of estimation and contr.l methods in quantum systems, and pr.vide a for.m for.idea exchange in this dynamic r.sear.h ar.a. Par.icular.y, lan r. Peter.en, a key figur. in the development of r.bust and quantum contr.l theor., just tur.ed 60 in the past year. We pr.pose to celebr.te this occasion with this special issue on quantum contr.l, one of his main r.sear.h focuses in the last fifteen year..

关键词：量子控制 LAN 生日量子计量学量子效应世界范围量子计算量子通信

Machine Lear.ing Techniques in Pr.dicting Hot Defor.ation Behavior.of Metallic Mater.als

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Computer.Modeling in Engineer.ng & Sciences 2025年第1期142卷 713-732页

作者： Petr.Opela Josef Walek Jar.mír.Kopecek Depar.ment of Metallur.ical Technologies Faculty of Materials Science and TechnologyVSB–Technical University of OstravaOstrava70800Czech Republic FZU—Institute of Physics of the Czech Academy of Sciences Prague18200Czech Republic

In engineer.ng pr.ctice,it is often necessar. to deter.ine functional r.lationships between dependent and independent *** r.lationships can be highly nonlinear.and classical r.gr.ssion appr.aches cannot always pr.vide sufficiently r.liable ***,Machine Lear.ing(ML)techniques,which offer.advanced r.gr.ssion tools to addr.ss complicated engineer.ng issues,have been developed and widely *** study investigates the selected ML techniques to evaluate their.suitability for.application in the hot defor.ation behavior.of metallic *** ML-based r.gr.ssion methods of Ar.ificial Neur.l Networ.s(ANNs),Suppor. Vector.Machine(SVM),Decision Tr.e r.gr.ssion(DTr.,and Gaussian Pr.cess r.gr.ssion(GPr.ar. applied to mathematically descr.be hot flow str.ss cur.e datasets acquir.d exper.mentally for.a medium-car.on *** the GPr.method has not been used for.such a r.gr.ssion task befor.,the r.sults showed that its per.or.ance is the most favor.ble and pr.ctically unr.valed;neither.the ANN method nor.the other.studied ML techniques pr.vide such pr.cise r.sults of the solved r.gr.ssion analysis.

关键词： Machine lear.ing Gaussian pr.cess r.gr.ssion ar.ificial neur.l networ.s suppor. vector.machine hot defor.ation behavior

Exter.al-beam r.diation ther.py should be given with andr.gen depr.vation tr.atment for.inter.ediate-r.sk pr.state cancer. new confir.ator. evidence

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Asian Jour.al of Andr.logy 2012年第1期14卷 132-133页

作者： matthew r.Cooper.er. Depar.ment of Ur.logy University of California San Francisco CA 94143-1695 USA

Anewly published study, r.diation Ther.py Oncology Gr.up （r.OG） tr.al 94-08, has demonstr.ted that a shor.-cour.e ofneoadjuvant andr.gen depr.vation ther.py （ADT） given together.with exter.al-beam r.diation ther.py （EBr.） impr.ves outcomes for.men with inter.ediate-r.sk pr.state cancer.compar.d with EBr. alone） The benefits of neoadjuvant ADT for.men r.ceiving EBr. have been r.cognized for.year., but in light of gr.wing concer.s r.gar.ing potential long-ter. skeletal, metabolic and car.iovascular.toxicities of ADT, the demonstr.tion of benefits with only shor.ter. tr.atment is timely.

关键词： Exter.al-beam r.diation ther.py inter.ediate-r.sk pr.state cancer neoadjuvant ADT r.OG 94-08 br.chyther.py

Inhibition of GABAA-ρr.ceptor. induces r.tina r.gener.tion in zebr.fish

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Neur.l r.gener.tion r.sear.h 2021年第2期16卷 367-374页

作者： matthew r.Kent Ner.is Kar. James G.Patton Depar.ment of Biological Sciences Vanderbilt UniversityNashvilleTNUSA

A potential tr.atment for.r.tinal diseases is to induce an endogenous Müller.glia(MG)-der.ved r.gener.tive r.sponse to r.place damaged *** contr.st to mammalian MG,zebr.fish MG ar. capable of mediating spontaneous *** seek to define the mechanisms that enable r.tina r.gener.tion in zebr.fish in or.er.to identify ther.peutic tar.ets to induce mammalian r.tina *** pr.viously used phar.acological and genetic methods to inhibit gamma aminobutyr.c acid A(GABAA)r.ceptor. in undamaged zebr.fish r.tinas and showed that such inhibition could induce initiation of r.tina r.gener.tion,as measur.d by the dediffer.ntiation of MG and the appear.nce of MG-der.ved pr.lifer.ting pr.genitor.***,we show that inhibition of a phar.acologically distinct subset of GABAA r.ceptor.(GABAA-ρ)can also induce r.tina *** inhibition of both GABA r.ceptor.subtypes led to enhanced r.tina *** expr.ssion analyses indicate that inhibition of GABAA-ρr.ceptor. induces a canonical r.tinal r.gener.tive *** r.sults suppor. a model in which decr.ased levels of GABA,such as would occur.after.r.tinal cell death or.damage,induce dediffer.ntiation of MG and the gener.tion of pr.lifer.ting pr.genitor.cells dur.ng zebr.fish r.tina *** exper.ments wer. appr.ved by the Vander.ilt's Institutional Animal Car. and Use Committee(Pr.tocol M1800200)on Januar. 29,2019.

关键词： gamma aminobutyr.c acid mor.holino Müller.glia neur.tr.nsmitter r.gener.tion r.tina stem cells zebr.fish

Pr.vention of lar.ngeal webs thr.ugh endoscopic keel placement for.bilater.l vocal cor. lesions

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Fr.ntier. of Medicine 2018年第3期12卷 301-306页

作者： Jian Chen Yilai Shu matthew r. Naunheim Min Chen Lei Cheng Haitao Wu Depar.ment of Otolar.ngology-Head and Neck Sur.er. Eye Ear Nose and Throat Hospital Fudan University Shanghai Key Clinical Disciplines of Otorhinolaryngology Shanghai 200031 China Depar.ment of Otology and Lar.ngology Harvard Medical School Boston MA 02138 USA Depar.ment of Otolar.ngology Massachusetts Eye and Ear Infirmary Boston MA 02138 USA

Tr.nsor.l micr.r.section for.tr.atment of vocal cor. lesions involving the anter.or.commissur. may r.sult in anter.or.glottic webs. In this study, we r.tr.spectively r.viewed 54 patients who under.ent micr.sur.er. for.bilater.l lesions involving the anter.or.commissur. and categor.zed them into two gr.ups. The keel placement and contr.l gr.ups r.ceived endoscopic keel placement and mitomycin C, r.spectively. Dur.ng the follow-up of at least 1 year. the lar.ngeal web for.ation r.te significantly decr.ased in the keel placement gr.up compar.d with that in the contr.l gr.up （18.6% ver.us 54.5%, P 〈 0.05）. Fur.her.or., the voice handicap index-10 scor.s for.patients without web for.ation decr.ased in both the keel placement and contr.l gr.ups （P 〈 0.0001 and P 〈 0.001, r.spectively）. A pseudomembr.ne cover.ng the vocal cor.s was detected in 16.3% （7 of 43） cases after.keel r.moval. A total of 100% （7 of 7） of these cases and 2.8% （1 of 36） of the other.cases for.ed lar.ngeal webs （P 〈 0.0001）. Endoscopic keel placement could be an effective method for.pr.venting anter.or.glottic webs after.sur.er. for.bilater.l vocal cor. diseases involving the anter.or.commissur.. The pseudomembr.ne obser.ed at the time of keel r.moval may imply a high r.sk of web for.ation.

关键词： glottic stenosis glottic web lar.ngeal keel silastic sheets anter.or.commissur.