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Status and prospects for symmetric organic redox flow batteries

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Journal of Energy chemistry 2025年第1期100卷 125-143页

作者： Md Al Raihan c.Adam Dyker Department of chemistry University of New Brunswick

As environmental concerns from fossil fuel consumption intensify, large-scale energy storage becomes imperative for the integration of renewable sources like wind, hydro, and solar with the electrical *** flow batteries, particularly those employing organic molecules, are positioned as a key technology for this purpose. This review explores the growing field of symmetric organic redox flow batteries(ORFBs) within this context. Unlike traditional asymmetric designs based on unique active materials for each electrode, symmetric ORFBs involve a single bipolar species for both electrodes. This review highlights the benefits of a symmetric design, and categorizes five distinct classes of organic bipolar molecules used in both aqueous and non-aqueous solvents. By providing a comprehensive overview of their cell cycling and performance characteristics, the strengths and weaknesses of the diverse categories of bipolar molecules are highlighted for both solvent systems, as are opportunities for future development. This should guide new research directions and advance the development of practical symmetric ORFBs.

关键词： Redox flow battery Symmetric battery Organic battery Aqueous electrolyte Non-aqueous electrolyte

Engineered hydrogels for brain tumor culture and therapy

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Bio-Design and Manufacturing 2020年第3期3卷 203-226页

作者： Jai Thakor Samad Ahadian Ali Niakan Ethan banton Fatemeh Nasrollahi Mohammad MHasani‑Sadrabadi Ali Khademhosseini center for Minimally Invasive Therapeutics(c‑MIT) University of California-Los Angeles570 Westwood PlazaLos AngelesCA 90095USA Department of Bioengineering University of California-Los AngelesLos AngelesCA 90095USA Department of Materials Science and Engineering University of California-Los AngelesLos AngelesCA 90095USA Weintraub center for Reconstructive Biotechnology Division of Advanced ProsthodonticsSchool of DentistryUniversity of California-Los AngelesLos AngelesCA 90095USA Department of Radiological Sciences University of California-Los AngelesLos AngelesCA 90095USA Department of chemical and Biomolecular Engineering University of California-Los AngelesLos AngelesCA 90095USA Terasaki Institute for Biomedical Innovation(TIBI) Los AngelesCA 90024USA

Brain tumors’severity ranges from benign to highly aggressive and *** tools can assist in understanding the pathophysiology of these tumors from outside the body and facilitate development of suitable antitumoral ***,we first describe the physiology and cellular composition of brain ***,we discuss the development of threedimensional tissue models utilizing brain tumor *** particular,we highlight the role of hydrogels in providing a biomimetic support for the cells to grow into defined *** technologies,such as electrospinning and bioprinting,and advanced cellular models aim to mimic the extracellular matrix and natural cellular localization in engineered tumor ***,we review current applications and prospects of hydrogels for therapeutic purposes,such as drug delivery and co-administration with other *** further development,hydrogels can serve as a reliable option for in vitro modeling and treatment of brain tumors for translational medicine.

关键词： Brain tumor Bioengineering cancer cells Drug delivery Hydrogel

The Restriction of Polynomial Modules for the Virasoro Algebra to sl_(2)(c)

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Algebra colloquium 2022年第3期29卷 491-508页

作者： matthew Ondrus Emilie Wiesner Mathematics Department Weber State UniversityOgdenUT 84408USA Department of Mathematics Ithaca CollegeIthacaNY 14850USA

The Lie algebra sl_(2)(c)may be regarded in a natural way as a subalgebra of the infinite-dimensional Virasoro Lie algebra,so it is natural to consider connections between the representation theory of the two *** this paper,we explore the restriction to sl_(2)(c)of certain induced modules for the Virasoro ***,we consider Virasoro modules induced from so-called polynomial subalgebras,and we show that the restriction of these modules results in twisted versions of familiar modules such as Verma modules and Whittaker modules.

关键词： Virasoro algebra induced modules automorphism twists

Acquired sensorineural hearing loss,oxidative stress,and microRNAs

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Neural Regeneration Research 2025年第9期20卷 2513-2519页

作者： Desmond A.Nunez Ru c.Guo Division of Otolaryngology–Head&Neck Surgery Department of SurgeryFaculty of MedicineThe University of British ColumbiaVancouverBCCanada Division of Otolaryngology–Head&Neck Surgery Gordon&Leslie Diamond Health Care CentreVancouver General HospitalVancouverBCCanada Faculty of Medicine–The University of British columbia VancouverBCCanada

Hearing loss is the third leading cause of human ***-related hearing loss,one type of acquired sensorineural hearing loss,is largely responsible for this escalating global health ***-induced,ototoxic,and idiopathic sudden sensorineural are other less common types of acquired hearing *** etiology of these conditions is complex and multi-fa ctorial involving an interplay of genetic and environmental *** stress has recently been proposed as a likely linking cause in most types of acquired sensorineural hearing *** non-coding RNA sequences known as microRNAs(miRNAs)have increasingly been shown to play a role in cellular hypoxia and oxidative stress responses including promoting an apoptotic *** hair cell death is a central histopathological finding in sensorineural hearing *** these cells do not regenerate in humans,it underlies the irreversibility of human age-related hearing *** EMBASE,Ovid MEDLINE,Web of Science core collection,and *** databases over the period August 1,2018 to July 31,2023 were searched with"hearing loss,""hypoxamiRs,""hypoxia,""microRNAs,""ischemia,"and"oxidative stress"text words for English language primary study publications or registered clinical *** red clinical trials known to the senior author we re also assessed.A total of 222studies were thus *** excluding duplicates,editorials,retra ctions,secondary research studies,and non-English language articles,39 primary studies and clinical trials underwent full-text *** resulted in 11 animal,in vitro,and/or human subject journal articles and 8 registered clinical trial database entries which form the basis of this narrative *** miR-34a and miR-29b levels increase with age in *** miRNAs were demonstrated in human neuroblastoma and murine cochlear cell lines to target Sirtuin 1/peroxisome proliferato r-activated receptor gamma coactivator-1-alpha(SIRT1/P Gc-1α),SIRT

关键词： hearing loss hypoxia microRNAs oxidative stress sensorineural

Extracellular DNA and autoimmune diseases

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cellular & Molecular Immunology 2018年第8期15卷 746-755页

作者： Hantao Lou matthew c Pickering Molecular Immunology Imperial College LondonLondon W120NNUK centre for complement and Inflammation Research Imperial College LondonLondon W120NNUK

Extracellular DNA is secreted from various sources including apoptotic cells,NETotic neutrophils and bacterial *** DNA can stimulate innate immune responses to induce type-I IFN production after being *** process is central in antiviral responses but it also plays important role in the pathogenesis of a range of autoimmune diseases such as systemic lupus *** discuss the recent advances in the understanding of the role of extracellular DNA,released from apoptotic and NETotic cells,in autoimmunity.

关键词： DNA type I IFN autoimmunity

Multiple sclerosis is at a checkpoint: advancing the program

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Neural Regeneration Research 2025年第3期20卷 811-812页

作者： Brandon c.Smith Jessica L.Williams Department of Neurosciences Lerner Research InstituteCleveland ClinicClevelandOHUSA Department of Biological Geologicaland Environmental SciencesCleveland State UniversityClevelandOHUSA

Multiple sclerosis(MS) is a chronic inflammatory and demyelinating disease of the central nervous system(cNS). Patients with MS experience sensory and motor function loss due to myelin and/or axon damage perpetuated b... 详细信息

关键词： Hauser sclerosis damage

Improved hemostasis with major hepatic resection in the current surgical era

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Hepatobiliary & Pancreatic Diseases International 2019年第5期18卷 439-445页

作者： christopher W Mangieri matthew A Strode Bradley c Bandera Department of Surgery Dwight D. Eisenhower Army Medical Center(DDEAMC)Fort GordonGA 30809USA Department of Surgical Oncology Roswell Park Cancer InstituteBuffaloNY 14203USA

Background: Major hepatic resection, predominantly performed for oncologic intent, is a complex procedure with the potential for severe intraoperative hemorrhage. The current surgical era has the ability to improve hemostasis throughout the performance of major hepatic resections which decreases blood transfusions and the detrimental effects associated with transfusion. We evaluated hemostasis and outcomes in the current surgical era of performing hepatic resections. Methods: Utilizing the American college of Surgeons (AcS) National Surgical Quality Improvement Program (NSQIP) database all major hepatic resections performed between 2012 and 2016 were analyzed in regards to hemostasis. Hemostasis was evaluated by the need for and magnitude of blood transfusions. Additional perioperative variables (including operative time, length of hospital stay, and mortality rates) were analyzed to assess for outcomes with hemostasis. The NSQIP results were compared to previous publications involving major hepatic resections to detect improvement in hemostasis and outcomes in the current surgical era. Results: A total of 22777 major hepatic resections met the inclusion criteria for analysis in the NSQIP database. An additional 21198 cases were compiled within the selected publications for comparative analysis. The transfusion rate in the current surgical era was 13.3% versus 38.7% in the previous era ( P = 0.0001). When a transfusion was required in the current surgical era there was a two-fold reduction in the number of units transfused (1.5 U vs. 3.8 U, P = 0.0001). Statistically significant improvements in operative time and length of hospital stay were presented within the current surgical era ( P = 0.0001). When a transfusion was required there was an increased relative risk score of 7 for mortality (4.9% vs. 0.7%, P = 0.0001), however, improvement in mortality rates did not reach statistical significance across surgical eras (1.3% vs. 4.0%, P = 0.0001). conclusions: The cond

关键词： Major hepatic resection Improved hemostasis Improved outcomes

A vector autoregression weather model for electricity supply and demand modeling

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Journal of Modern Power Systems and clean Energy 2018年第4期6卷 763-776页

作者： Yixian LIU matthew c.ROBERTS Ramteen SIOSHANSI Department of Integrated Systems Engineering The Ohio State University Department of Agricultural Environmental and Development Economics The Ohio State University

Weather forecasting is crucial to both the demand and supply sides of electricity systems. Temperature has a great effect on the demand side. Moreover, solar and wind are very promising renewable energy sources and are, thus, important on the supply side. In this paper, a large vector autoregression(VAR) model is built to forecast three important weather variables for 61 cities around the United States. The three variables at all locations are modeled as response variables. Lag terms are used to capture the relationship between observations in adjacent periods and daily and annual seasonality are modeled to consider the correlation between the same periods in adjacent days and years. We estimate the VAR model with16 years of hourly historical data and use two additional years of data for out-of-sample validation. Forecasts of up to six-hours-ahead are generated with good forecasting performance based on mean absolute error, root mean square error, relative root mean square error, and skill scores. Our VAR model gives forecasts with skill scoresthat are more than double the skill scores of other forecasting models in the literature. Our model also provides forecasts that outperform persistence forecasts by between6% and 80% in terms of mean absolute error. Our results show that the proposed time series approach is appropriate for very short-term forecasting of hourly solar radiation,temperature, and wind speed.

关键词： Forecasting Solar irradiance Wind speed Temperature Vector autoregression Skill scores

Isolation of Single-Walled carbon Nanotube Enantiomers by Density Differentiation

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Nano Research 2009年第1期2卷 69-77页

作者： Alexander A.Green matthew c.Duch Mark c.Hersam Department of Materials Science and Engineering and Department of chemistry Northwestern UniversityEvanstonIllinois 60208-3108USA

current methods of synthesizing single-walled carbon nanotubes(SWNTs)result in racemic mixtures that have impeded the study of left-and right-handed *** we present a method of isolating different SWNT enantiomers using density gradient *** separation is enabled by the chiral surfactant sodium cholate,which discriminates between left-and right-handed SWNTs and thus induces subtle differences in their buoyant *** sorting strategy can be employed for simultaneous enrichment by handedness and roll-up vector of SWNTs having diameters ranging from 0.7 to 1.5 *** addition,circular dichroism of enantiomer refined samples enables identification of high-energy optical transitions in SWNTs.

关键词： carbon nanotube separation handedness enantiomer optical activity chirality