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SURFACE MODIFICATION OF POLYPROPYLENE MICROPOROUS MEMBRANE BY TETHERING POLYPEPTIDES

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Chinese Journal of Polymer Science 2006年第5期24卷 529-538页

作者：徐志康 mathias Ulbricht Institute of Polymer Science Department of Polymer Science & Engineering Zhejiang University Hangzhou 310027 China Institut für Technische Chemie Universit t Duisburg-Essen45117 EssenGermany

Two kinds of polypeptides were tethered onto the surface of polypropylene microporous membrane （PPMM） through a ring opening polymerization of L-glutamate N-carboxyanhydride initiated by amino groups which were introduced by ammonia plasma and y-aminopropyl triethanoxysilane treatments. X-ray photoelectron spectroscopy （XPS）, attenuated total reflectance Fourier transform infrared spectroscopy （FT-IR/ATR）, scanning electron microscopy （SEM）, together with water contact angle measurements were used to characterize the modified membranes. XPS analyses and FT-IR/ATR spectra demonstrated that polypeptides are actually grafted onto the membrane surface. The wettability of the membrane surface increases at first and then decreases with the increase in grafting degrees of polypeptide. Platelet adhesion and murine macrophage attachment experiments reveal an enhanced hemocompatibility for the polypeptide modified PPMMs. All these results give evidence that polypeptide grafting can simultaneously improve the hemocompatibility as well as reserve the hydrophobicity for the membrane, which will provide a potential approach to improve the performance of polypropylene hollow fiber microporous membrane used in artificial oxygenator.

关键词： Polypropylene microporous membrane Graft polymerization Polypeptide Surface modification Biocompatibility.

Fine-Tuning by the Touch of Big Dudes: SUMOs Role in Light Signaling

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Molecular Plant 2020年第7期13卷 943-945页

作者： mathias Zeidler Institute of Plant Physiology Justus-Liebig-University GiessenSenckenbergstrasse 335390 GiessenGermany

Protein posttranslational modifications(PTM)are recognized to be important regulators for protein function,activity,localization,and/or stability and are a substantial component in the cell’s proteome *** the possible PTMs,the small ubiquitin-related modifiers(SUMO)have long had inferior standing to phosphorylation and ubiquitination.

关键词： SUMO phosphorylation stability

Functional hyperconnectivity related to brain disease:maladaptive process or element of resilience?

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Neural Regeneration Research 2023年第7期18卷 1489-1490页

作者： Markus Aswendt mathias Hoehn Department of Neurology Faculty of Medicine and University Hospital CologneUniversity of CologneCologneGermany Cognitive Neuroscience Institute of Neuroscience and Medicine(INM-3)Research Center JuelichJuelichGermany

Neuroimaging techniques such as magnetic resonance imaging(MRI)and positron emission tomography provide unique in vivo data to analyze structural and functional connectivity of the whole *** advances in small animal neuroimaging have opened new opportunities for the study of structure-function interactions in healthy and diseased brain networks,which are essential to develop therapies targeting network reorganization associated with functional improvement.

关键词： network connectivity element

Defensins couple dysbiosis to primary immunodeficiency in Crohn's disease

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World Journal of Gastroenterology 2011年第5期17卷 567-571页

作者： mathias Chamaillard Rodrigue Dessein Institut Pasteur de Lille Center for Infection and Immunity of LilleF-59019 LilleFrance Mathias ChamaillardRodrigue DesseinCNRSUMR 8204F-59021 LilleFrance Institut National de la Santé et de la Recherche Médicale U1019Team 7Equipe FRMF-59019 LilleFrance Univ Lille Nord de France F-59000 LilleFrance C.H.R.U.de Lille F-59000 LilleFrance

Antimicrobial peptides,including defensins,are essential effectors in host defence and in the maintenance of immune *** studies have linked the defective expression of both α-and β-defensin to the reduced killing of certain microorganisms by the intestinal mucosa of patients suffering from ileal and colonic Crohn's disease(CD),*** recently have the events leading to defective expression of defensins in CD been further elucidated,and are discussed *** events may account for CD-associated alterations in the microbiome and may subsequently precipitate the development of granulomatous inflammatory lesions in genetically-predisposed *** also address how these discoveries may pave the way for the development of a molecular medicine aimed at restoring gut barrier function in CD.

关键词： Crohn's disease Defensins Primary immuno-deficiencies

APPROXIMATING THE STATIONARY BELLMAN EQUATION BY HIERARCHICAL TENSOR PRODUCTS

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Journal of Computational Mathematics 2024年第3期42卷 638-661页

作者： mathias Oster Leon Sallandt Reinhold Schneider Technische Universität Berlin Strasse des 17.Juni 13510623 BerlinGermany

We treat infinite horizon optimal control problems by solving the associated stationary Bellman equation numerically to compute the value function and an optimal feedback *** dynamical systems under consideration are spatial discretizations of non linear parabolic partial differential equations(PDE),which means that the Bellman equation suffers from the curse of *** non linearity is handled by the Policy Iteration algorithm,where the problem is reduced to a sequence of linear equations,which remain the computational bottleneck due to their high *** reformulate the linearized Bellman equations via the Koopman operator into an operator equation,that is solved using a minimal residual *** the Koopman operator we identify a preconditioner for operator equation,which deems essential in our numerical *** overcome computational infeasability we use low rank hierarchical tensor product approximation/tree-based tensor formats,in particular tensor trains(TT tensors)and multi-polynomials,together with high-dimensional quadrature,*** controlling a destabilized version of viscous Burgers and a diffusion equation with unstable reaction term numerical evidence is given.

关键词： Feedback control Dynamic programming Hamilton-Jacobi-Bellman Tensor product approximation Variational Monte-Carlo

Recruitment in species-rich grasslands: the effects of functional traits and propagule pressure

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Journal of Plant Ecology 2012年第3期5卷 260-269页

作者： mathiasÖster Ove Eriksson Department of Botany Stockholm UniversitySE-10691 StockholmSweden

Aims The assembly of plant communities is a complex process which combines impacts from the species pool,dispersal and propagule pressure,niche requirements of colonizing species and the niche structure of the *** theory development has incorporated all these aspects,***‘stochastic niche theory’.We investigated recruitment into a species-rich grassland community,using an experimental approach where we manipulated the trait composition of the community and examined the success of colonizing species entering with various propagule ***,we examined two predictions:(i)colonization success increases with increasing difference between traits of the colonizing species and the trait profile of the community and(ii)colonization success increases with increasing propagule *** The examined communities were species-rich semi-natural grasslands located in southern *** a careful documentation of the composition of the plant communities at the experimental sites,we manipulated the trait profile of species-rich grassland plots based on the plant functional trait specific leaf area(SLA),which is correlated with several key life history *** addition to SLA,seed mass was also used to describe the trait profile of grassland *** of 12 plant species from the regional species pool,varying in SLA and seed mass,were sown into plots using four different levels of propagule *** was examined after 1 *** also planted juvenile‘plug plants’of the same species which allowed us to examine survivorship and growth beyond the seedling *** Findings Overall we found very limited evidence for relationships between the traits of the colonizing species and the trait profile of the community and for recruitment after sowing these relationships were contrary to the *** of plug plants after two seasons of growth was high irrespective of the trait profile of the community,but growth of plug

关键词： assembly rules recruitment limitation seed size semi-natural grassland SLA

Mapping of Tonoplast Intrinsic Proteins in Maturing and Germinating Arabidopsis Seeds Reveals Dual Localization of Embryonic TIPS to the Tonoplast and Plasma Membrane

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Molecular Plant 2011年第1期4卷 180-189页

作者： Stefano Gattolin mathias Sorieul Lorenzo Frigerio Department of Biological Sciences University of Warwick Coventry CV4 7AL UK

We have mapped the expression of the tonoplast intrinsic protein （TIP） gene family members in Arabidopsis seeds by fluorescent protein tagging of their genomic sequences and confocal microscopy. Three isoforms （TIP1;1, TIP2;1, and TIP2;2） have distinct patterns of expression in maternal tissues （outer integument and placento-chalazal region）. Two isoforms, TIP3;1 and the previously uncharacterized TIP3;2, are the only detectable TIPs in embryos during seed maturation and the early stages of seed germination. Throughout these developmental stages, both isoforms co-locate to the tono- plast of the protein storage vacuoles, but also appear to label the plasma membrane. Plasma membrane labeling is specific to TIP3;1 and TIP3;2, is independent of the position of the fluorescent protein tag, and appears to be specific to early seed maturation and early germination stages. We discuss these results in the context of the predicted distribution of aquaporins in Arabidopsis seeds.

关键词： Aquaporin vacuole tonoplast intrinsic protein Arabidopsis seed embryo protein storage endosperm endoplasmic reticulum fluorescent protein.

Auxin-Oxylipin Crosstalk:Relationship of Antagonists

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Journal of Integrative Plant Biology 2011年第6期53卷 429-445页

作者： Maik Hoffmann mathias Hentrich Stephan Pollmann Centro de Biotecnología y Genómica de Plantas(U.P.M.-I.N.I.A.) Parque Científico y Tecnológico de la U.P.M. Campus de Montegancedo Ruhr-Universitt Bochum Lehrstuhl fr PflanzenphysiologieUniversittsstrasse

Phytohormones regulate a wide array of developmental processes throughout the life cycle of plants. Herein, the various plant hormones may interact additively, synergistically, or antagonistically. By their cooperation they create a delicate regulatory network whose net output largely depends on the action of specific phytohormone combinations rather than on the independent activities of separate hormones. While most classical studies of plant hormonal control have focused mainly on the action of single hormones or on the synergistic interaction of hormones in regulating various developmental processes, recent work is beginning to shed light on the crosstalk of nominally antagonistic plant hormones, such as gibberellins and auxins with oxylipins or abscisic acid. In this review, we summarize our current understanding of how two of the first sight antagonistic plant hormones, i.e. auxins and oxylipins, interact in controlling plant responses and development.

关键词： Auxin biosynthesis crosstalk hormone jasmonic acid.

Blockchain Energy: Blockchain in Future Energy Systems

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Journal of Electronic Science and Technology 2019年第4期17卷 317-331页

作者： Bernd Teufel Anton Sentic mathias Barmet international institute of management in technology University of Fribourg

The ongoing,in-depth transformation of the electricity sector towards increased use of alternative,renewable energy sources extends beyond a simple decentralisation drive in the electricity *** transformation process is characterised by the interplay of old and new technologies from the energy sector as well as structural coupling with other sectors,such as the information and communications technology(ICT),enabling the technology transfer as well as market entry by information technology(IT)***-based technologies have the potential to play a key role in this transition by offering decentralised interfaces and systems as well as an alternative approach to the current organisation form of the energy *** paper discusses the applicability and prospects for blockchain-based technologies in the energy sector,which are described using the term“blockchain energy”.For the purposes of this study,blockchain energy encompasses all socio-technical and organisational configurations in the energy sector based on the utilisation of the blockchain principle for energy trading,information storage,and/or increased transparency of energy flows and energy *** the following chapters,the authors present and discuss the current transformation in the electricity market,followed by a review of the different utilisation possibilities for blockchain technologies in the energy sector and a discussion of the barriers and potential for blockchain energy using a transition studies ***,the opportunities and risks of blockchain energy are discussed.

关键词： Blockchain energy management crowd energy transition research.