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Integrated sensing and delivery of oxygen for next- generation smart wound dressings

Microsystems & Nanoengineering 2020年第1期6卷 991-1006页

作者： Manuel Ochoa Rahim Rahimi Jiawei zhou Hongjie Jiang Chang Keun Yoon Dinesh Maddipatla Binu Baby Narakathu Vaibhav Jain Mark Michael Oscai Thaddeus Joseph Morken Rebeca Hannah Oliveira Gonzalo L.Campana Oscar W.Cummings Michael A.zieger Rajiv Sood massood z.atashbar Babak ziaie School of Electrical and Computer Engineering Purdue UniversityWest Lafayette 47907 INUSA Birck Nanotechnololgy Center 1205W State StreetWest Lafayette 47907 INUSA School of Material Science Engineering Purdue UniversityWest Lafayette 47907 INUSA Electrical and Computer Engineering Department Western Michigan University4601 Campus Drive B-236Kalamazoo 49008 MIUSA School of Mechanical Engineering Purdue UniversityWest Lafayette 47907 INUSA Indiana University School of Medicine 980 West Walnut StreetBuilding R3 Room C634Indianapolis 46202 INUSA Department of Pathology and Laboratory Medicine Indiana University School of MedicineIU Health Pathology Laboratory350W 11th StreetRoom 4054IndianapolisIN 46202USA Weldon School of Biomedical Engineering Purdue UniversityWest Lafayette 47907 INUSA Present address:Shenzhen MSU-BIT University ShenzhenChina

Chronic wounds affect over 6.5 million Americans and are notoriously difficult to *** oxygenation of the wound bed is one of the most critical and treatable wound management factors,but existing oxygenation systems do not enable concurrent measurement and delivery of oxygen in a convenient wearable ***,we developed a low-cost alternative for continuous O 2 delivery and sensing comprising of an inexpensive,paper-based,biocompatible,flexible platform for locally generating and measuring oxygen in a wound *** platform takes advantage of recent developments in the fabrication of flexible microsystems including the incorporation of paper as a substrate and the use of a scalable manufacturing technology,inkjet ***,we demonstrate the functionality of the oxygenation patch,capable of increasing oxygen concentration in a gel substrate by 13%(5ppm)in *** platform is able to sense oxygen in a range of 5–26 *** vivo studies demonstrate the biocompatibility of the patch and its ability to double or triple the oxygen level in the wound bed to clinically relevant levels.

关键词： patch smart printing

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Determination of the strong coupling constant using available experimental data

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Chinese Physics C 2010年第9期34卷 1485-1487页

作者： S.atashbar Tehrani A.N.Khorramian School of Particles and Accelerators Institute for Research in Fundamental Sciences (IPM) Physics Department Semnan University

We determine the strong coupling constant α s up to 4-loop in perturbative *** QCD requires the measurement of α s over ranges of energy *** this analysis,the value of α s is determined from the unpolarized structure functions data points by minimizing the χ ^2 function between the theory result and experimental *** perturbative QCD calculations from threshold corrections,we obtain α s （M 2 z ） = 0.1139±0.0020 at N ^3 LO which is in good agreement with the very recently results from the inclusive jet cross section in pp collisions at√ s=1.96 TeV.

关键词： strong coupling DIS data N ^3 LO

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Correlation between Cognitive Functions, Fatigue, Depression and Disability Status in a Cohort of Multiple Sclerosis Patients

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World Journal of Neuroscience 2016年第3期6卷 208-213页

作者： Seyed massood Nabavi S. Tahbaz A. Salahesh z. Behjati F. Nourbala S. Sadeghi z. Saeedi D. Morsali Shima Haghani Center for Neuroscience and Cognition Royan Institute Tehran Iran Iranian Journal of Neurology Iranian Neurological Association Tehran Iran Psychology Department Shahid Behehsty University Tehran Iran Multiple Sclerosis Research Unit Mostafa Medical Center Shahed University Tehran Iran Avicenna Research Institute Shahid Beheshti University Tehran Iran zendegi Psychology Services Center Tehran Iran Young Researchers and Elite Club Azad University Tehran Iran Neurology Department Medical Faculty University of Texas Health Huston TX USA Clinical Research Department Tehran Heart Center Tehran Iran

Objective: To investigate the relationship between depression, fatigue, disability and cognitive skills of patients with multiple sclerosis in a cohort of patients with multiple sclerosis in a single center in Tehran, Iran. Methods: One hundred and forty-seven patients with multiple sclerosis with mean age of 33 years, mean disease duration of 20.20 months, mean EDSS of 2.13, and F to M ratio of 76.5% over 23% were recruited for the purpose of this study. Cognitive function was compared with healthy control subjects (n = 100). Depression was measured by Beck Depression Inventory (BDI), fatigue was assessed using Fatigue Severity Scale (FSS) and Modified Fatigue Impact Scale (MFIS), disability was evaluated by Expanded Disability Status Scale (EDSS), and cognitive function was assessed by Brief Repeatable Battery of Neuropsychological tests (BRB-N). All data were analysed using Pearson correlation. Results: Age and disability level generally correlated negatively and significantly with task performance, whereas a higher level of education was associated with better task performance. While the correlation between BDI, FSS, and MIFS was significantly positive, BDI was negatively correlated with the two subscales of BRB, namely PASAT and WLG. Higher levels of depression in patients with MS are associated with lower cognitive performance in tasks requiring higher-order working memory (WM) processes. FSS showed the strongest negative correlation score with BRB, however, the same parameter displayed significant positive correlation with MFIS. Moreover, the global EDSS scores were negatively correlated with BRB. Relative to controls, cognitive performance of MS patients was deficient in all BRB-N measures except Symbol Digit Modalities Test which is a measure of attention and processing speed. Conclusions: Depression, fatigue, and disability (the most common problems observed in MS patients) are clearly related with cognitive impairment in MS patients. Also, MS patients exh

关键词： Fatigue Depression Cognitive Dysfunction Disability Multiple Sclerosis

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