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The Neurologist in the Emergency Room: Prospective Study of the Neurological Emergency Group in Lombardia

Journal of Health Science 2019年第4期7卷 254-261页

作者： MariaLuisa Delodovici Marco Mauri Megi Meneri Marco Gallazzi Elena Ballabio Giuseppina Borutti Maria Vittoria Calloni Elisa Candeloro Bruno Censori Claudio De Piazza Laura Fusi Franca Mazzucchelli Ignazio Santilli Elisabetta Forapani Chiara Scaccabarozzi Maria Sessa Lucia Tancredi massimiliano braga Dept. of Neurology and Stroke Unit Ospedale di Circolo e Fondazione MacchiUniversità dell’InsubriaASST-Settelaghile Luigi Borri 57 21100 VareseItaly Dept. of Neurology Ospedale di Desio (MB) Director G. Mazzini 1 20832 Desio (MB)Italy Dept. of Neurology ASST Lecco-Ospedale A. Manzonidell’Eremo 9/11 23900 LeccoItaly Dept. of Neurology Ospedale di Cremona ASST Cremona Directorle Concordia 1 26100 CremonaItaly Dept. of Neurology Ospedale Sant’Anna ComoRavona 20 22042 SFermo della BattagliaComoItaly Dept. of Neurology Ospedale di Vimercate (MB) Santi Cosma e Damiano 10 20871 Vimercate (MB)Italy Dept. of Neurology Ospedale S. Carlo BorromeoA. Mosca 12 20152 MilanoItaly Dept. of Neurology Director Ospedale Civile di VogheraVolturno 14 Voghera 27058 (PV)Italy Dept. of Neurology Ospedale di Legnano ASST Ovest MilanesePapa Giovanni Paolo II20025 Legnano (MI)Italy Dept. of Neurology Fondazione IRCCS C. Mondino Mondino 2Pavia 27100Italy Dept. of Neurology ASST Papa Giovanni XXIII Piazza OMS 1 24127 BergamoItaly Dept. of Neurology Ospedale Valduce ComoDante Alighieri 11 22100 ComoItaly Dept. of Neurology Ospedale di Saronno ASST Valle olonaPiazzale Borella 1 Saronno 21047 (VA)Italy Dept. of Neurology Ospedale S. Antonio Abate Gallarate. Pastori 4 21013 Gallarate VareseItaly

Purpose of the work was to quantify the workloads and the neurologist’s commitment in ER, to verify the management of urgencies and appropriateness of neurological counseling requests. Neurologic emergencies are frequent in elderly patients and are associated with high morbidity and mortality. Due to the aging population, neurologic pathologies in emergency room (ER) are widely expected to increase. The role of the neurologist in this context is controversial. Methods: in 14 operative units of neurology a prospective collection of neurological evaluations in ER was carried out using boards of detection of the most frequent neurological clinical pictures seen in the course of a week. Data were collected from 738 cases. Attention was focused on cerebrovascular diseases (CVD), impairment of consciousness, epilepsy, headache, dizziness, head trauma and disorders of the peripheral nervous system (PNS). Achievements: neurological consultations were on average 5% of total accesses to ER. The most common pathology seen was ischemic stroke. After counseling most patients were discharged home. The CVD required the greatest commitment to the specialist. The usefulness of the specialized neurological “filter” has been confirmed in a non-simple operative context, aimed at optimizing the appropriateness of the hospitalization and the economy of the diagnostic path.

关键词： Emergency room neurological diseases neurology workload

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MHD Equilibrium with Reversed Current Density and Magnetic Islands Revisited:the Vacuum Vector Potential Calculus

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Plasma Science and Technology 2013年第10期15卷 985-988页

作者： F.L.braga Gleb-Wataghin Physics Institute Applied Physics DepartmentState University of Campinas Federal Institute of Science and Technology of Espirito Santo

The solution of Grad-Shafranov equation determines the stationary behavior of fusion plasma inside a tokamak. To solve the equation it is necessary to know the toroidal current density profile. Recent works show that it is possible to determine a magnetohydrodynamic （MHD） equilibrium with reversed current density （RCD） profiles that presents magnetic islands. In this work we show analytical MHD equilibrium with a RCD profile and analyze the structure of the vacuum vector potential associated with these equilibria using the virtual casing principle.

关键词： magnetohydrodynamics vacuum vector potential reversed current density magnetic islands

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RCD Large Aspect-Ratio Tokamak Equilibrium with Magnetic Islands:a Perturbed Approach

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Communications in Theoretical Physics 2013年第3期59卷 375-378页

作者： F.L.braga Instituto de Física Gleb Wataghin Departamento de Física AplicadaUniversidade Estadual de CampinasCampinasSP13083-859Brasil Instituto Federal de Ci encias e Tecnologia do Esp' rito Santo Campus Santa TeresaES29600-000Brasil

Solutions of Grad-Shafranov （CS） equation with Reversed Current Density （RCD） profiles present mag- netic islands when the magnetic flux is explicitly dependent on the poloidal angle. In this work it is shown that a typical cylindrical （large aspect-ratio） RCD equilibrium configuration perturbed by the magnetic field of a circular loop （simulating a divertor） is capable of generate magnetic islands, due to the poloidal symmetry break of the GS equilibrium solution.

关键词： symmetry break magnetic islands Grad-Shafranov equation reversed current density

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Brazilian traditional medicine:Historical basis,features and potentialities for pharmaceutical development

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Journal of Traditional Chinese Medical Sciences 2021年第S1期8卷 44-50页

作者： Fernão Castro braga Faculty of Pharmacy Federal University of Minas GeraisAv.Ant(o)nio Carlos 6627campus PampulhaBelo Horizonte30.140-170Brazil

This article gives a brief overview on the Brazilian traditional medicine,starting from its historical development based on the cultural mixing of indigenous populations,European colonizers,and African *** the sequence,it analyzes some features that contributed to the gradual loss of interest on medicinal plants in Brazil,a process started in the 1950s,and recent initiatives undertaken to valuate the Brazilian traditional ***,it highlights some drugs developed from or based on con-stituents of the Brazilian biodiversity and traditional knowledge,which are globally employed,and the perspectives for new drugs *** also discusses the sanitary requirements currently adopted in Brazil for the development and registration of medicinal products based on the Brazilian biodiversity and associated traditional knowledge,as well as the impact of new *** addition,it is presented a discussion on the regulatory framework to access to genetic heritage and associated traditional knowledge in Brazil,along with its impact on the development of pharmaceutical ***,some attempts are made to indicate the possible causes that limit the development of products based on the genetic heritage of Brazilian plants and associated traditional knowledge.

关键词： features globally starting

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Tree structure and diversity of lowland Atlantic forest fragments：comparison of disturbed and undisturbed remnants

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Journal of Forestry Research 2016年第3期27卷 605-609页

作者： Fabricio Alvim Carvalho Joao Marcelo Alvarenga braga Marcelo Trindade Nascimento Departamento de Botanica Universidade Federal de Juiz de Fora. Campus Universitario s/n Sao PedroJuiz de Fora-MG 36036-900 Brazil Instituto de Pesquisas do Jardim Botanico do Rio de Janeiro. Rio de Janeiro-RJ Brazil Laboratorio de Ciencias Ambientais CBB Universidade Estadual do Norte Fluminense Campos dos Goytacazes-RJ 28013-602 Brazil

This study describes the tree community structure of three moist lowland Atlantic Forest fragments in Rio de Janeiro State, southeastern Brazil. Two fragments were disturbed and an undisturbed one was used as reference. Our hypothesis was that disturbed fragments show distinct structural patterns in comparison with undisturbed stands due to past disturbance practices and forest fragmentation. Four 100 ×5 m sampling plots were demarcated in each fragment and all live and dead trees with DBH C 5 cm were located, measured and identified. The results supported our hypothesis, due to the high values found for standing dead trees, an increase of dominance of a few pioneer species, lower values of large trees and species richness in disturbed fragments in comparison with the undisturbed one. The advanced fragmentation process in the Southern Brazilian lowland areas and the high species richness in undisturbed areas highlight these forest fragments as priority areas for conservation and management.

关键词： Phytosociology Tree community Forestfragmentation . Hotspot Brazil

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Relation between skeletal muscle volume and prognosis in rectal cancer patients undergoing neoadjuvant therapy

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World Journal of Gastrointestinal Oncology 2022年第2期14卷 423-433页

作者： Paola De Nardi Alessandro Giani Giulia Maggi Marco braga Department of Gastrointestinal Surgery IRCCS San Raffaele Scientific InstituteMilano 20132Italy Department of Surgery School of MedicineUniversity of Milano-BicoccaMilan ItalyMonza 20900Italy Department of Oncologic Surgery Policlinico CasilinoRome 00169Italy Department of Surgery San Gerardo HospitalUniversity Milano BicoccaMonza 20900Italy

The prognostic role of body composition indexes,and specifically sarcopenia,has recently been explored in different cancer ***,conflicting results have been *** in cancer type,cancer stage or oncological treatments,as well as different methodology and definition of sarcopenia,could be accounted for different conclusions retrieved from *** focusing on colorectal cancer,it clearly appears that colon and rectal cancers are often treated as a single entity though they have different behaviors and ***,patients with advanced rectal cancer represent a peculiar group of patients that according to current guidelines are treated with neoadjuvant chemotherapy and radiotherapy followed by radical *** review was restricted to a homogeneous group of patients with advanced lower rectal cancer and the aim of exploring whether there is a correlation between skeletal muscle depletion and *** was searched for articles related to patients with advanced rectal cancer undergoing neoadjuvant chemo-radiotherapy(NCRT)followed by radical surgery,in whom muscle mass and/or change in muscle mass during neoadjuvant treatment were *** full-text articles were selected and included in the present *** main findings of our review were:(1)The majority of the studies defined sarcopenia as muscle mass alone over muscle strength or physical performance;(2)There was a great deal of heterogeneity in the definition and measures of sarcopenia,in the definition of cut-off values,and in the method to measure change in muscle mass;(3)There was not full agreement on the association between sarcopenia at baseline and/or after chemoradiotherapy and prognosis,and only few studies found a significance in the multivariate analysis;and(4)It seems that a loss in skeletal muscle mass during NCRT is associated with the worst outcomes in terms of disease-free *** conclusion,analysis of muscle mass might provid

关键词： Advanced rectal cancer Sarcopenia Neoadjuvant treatment Chemoradiotherapy Surgery Muscle mass change Prognosis Survival Review

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Nutrient optimization for plant growth in Aquaponic irrigation using Machine Learning for small training datasets

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Artificial Intelligence in Agriculture 2022年第1期6卷 68-76页

作者： Sambandh Bhusan Dhal Muthukumar Bagavathiannan Ulisses braga-Neto Stavros Kalafatis Department of Electrical and Computer Engineering Texas A&M UniversityUSA Department of Soil and Crop Sciences Texas A&M UniversityUSA

With the recent trends in urban agriculture and climate change,there is an emerging need for alternative plant culture techniques where dependence on soil can be *** and aquaponic growth techniques have proven to be viable alternatives,but the lack of efficient and optimal practices for irrigation and nutrient supply limits its applications on a large-scale commercial *** main purpose of this research was to develop statistical methods and Machine Learning algorithms to regulate nutrient concentrations in aquaponic irrigation water based on plant needs,for achieving optimal plant growth and promoting broader adoption of aquaponic culture on a commercial *** of the key challenges to developing these algorithms is the sparsity of data which requires the use of Bolstered error estimation *** this paper,several linear and non-linear algorithms trained on relatively small datasets using Bolstered error estimation techniques were evaluated,for selecting the best method in making decisions regarding the regulation of nutrients in hydroponic *** repeated tests on the dataset,it was decided that Semi-Bolstered Resubstitution Error estimation technique works best in our case using Linear Support Vector Machine as the classifier with the value of penalty parameter set to one.A set of recommended rules have been prescribed as a Decision Support System,using the output of the Machine Learning algorithm,which have been tested against the results of the baseline ***,the positive impact of the recommended nutrient concentrationson plant growth in aquaponic environments has been elaborately discussed.

关键词： Hydroponic Aquaponic Training datasets Non-linear algorithms Semi-bolstered error estimation Linear support vector machine Decision Support System

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Use of omental patch and endoscopic closure technique as an alternative to surgery after endoscopic full thickness resection of gastric intestinal stromal tumors: A series of cases

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World Journal of Clinical Cases 2020年第1期8卷 120-125页

作者： Amit H Sachdev Shahzad Iqbal Igor braga Ribeiro Diogo Turiani Hourneaux de Moura Division of Gastroenterology Hepatology and EndoscopyBrigham and Women’s HospitalHarvard Medical SchoolBostonMA 02115United States Good Samaritan Hospital NY 11795United States Gastrointestinal Endoscopy Unit Hospital das Clínicas da Faculdade de Medicina da Universidade de São PauloSão Paulo 05403-000Brazil

BACKGROUND Gastrointestinal stromal tumors(GISTs)originate from interstitial cells of *** can occur anywhere along the gastrointestinal *** lesions have traditionally been removed ***,with recent innovations in advanced endoscopy,GISTs located within the stomach are now removed *** describe a new innovative endoscopic technique to close large and hard to access defects after endoscopic full-thickness resection of gastric *** SUMMARY We present a series of three patients who were diagnosed with a gastric *** patients underwent full-thickness endoscopic *** all cases,for closure of the surgical bed,conventional endoscopic techniques including hemoclips,endoloop and suturing were *** performed a new technique in which we pulled omental fat into the gastric lumen and completely closed the defect using endoscopic *** patients performed well post-procedure and computed tomography was carried out one day after the procedures which showed no extravasation of *** The omental plug technique may be used as an alternative to surgery in selected cases of gastric perforation.

关键词： Gastric perforation Gastrointestinal stromal tumors Gastric tumor Surgery Endoscopy Suturing

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Nutrition Care and Minimally Invasive Pathway in Surgical Cancer Patients

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Journal of Nutritional Oncology 2017年第4期2卷 153-158页

作者： Marco braga Department of Surgery San Raffaele University Hospital20132 MilanItaly

Nutritional status is often neglected or under evaluated in patients with cancer,despite international guidelines suggest that nutritional deterioration negatively affects patients’*** malnutrition increases postoperative complications and mortality and prolongs hospital *** support must be given to undernourished cancer patients,as it can bring many clinical and economic ***,an inadequate nutritional support for cancer patients should be considered ethically *** invasive surgical techniques result in less operative blood loss,decreased surgical stress response,and less postoperative pain and *** associated to enhanced recovery pathway(ERP),a quicker recovery and a shorter hospital stay are *** far,routine nutritional care and ERP have only been incorporated into the clinical practice in a minority of *** reasons are an insufficient awareness of the clinical relevance of undernutrition and a lack of structured collaboration between surgeons and clinical nutrition *** review suggests that a better cooperation among healthcare providers,patients,and families would bring tremendous clinical benefits to patients with cancer,especially those undergoing surgery,radiotherapy,and chemotherapy.

关键词： Cancer Nutritional Status Sarcopenia Immunonutrition Laparoscopic Surgery Enhanced recovery after surgery

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Distribution of the related weevil species Sitophilus oryzae and S. zeamais in Brazil

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Insect Science 2013年第6期20卷 763-770页

作者： Alberto S. Correa Luiz Orlando de Oliveira Lucas S. braga Raul Narciso C. Guedes Departamento de Entomologia Universidade Federal de Vicosa Vicosa Brazil Departamento de Bioquimica e Biologia Molecular Universidade Federal de Vicosa Vicosa Brazil

The genus Sitophilus （Coleoptera： Curculionidae） encompasses species of great economic importance as stored grain pests worldwide. Among these species, the maize and the rice weevils （Sitophilus zeamais and Sitophilus oryzae, respectively） are partic- ularly important in warmer climates. These two weevils exhibit closely morphological and ecological resemblance making difficult their proper identification and recognition of their distribution in grain-producing regions. Both species are recorded in South America and particularly in Brazil, but their respective distribution and prevalence were not yet assessed in the region. Therefore, several insect samples throughout Brazil were collected and subjected to morphological identification using male genitalia and also using molec- ular identification with species-specific primers designed for clear recognition of both the species. The primers were designed for the specific amplification of a gene fragment of the cytochrome oxidase subunit I, which exhibited high specificity during our prelimi- nary experiments with insects from six populations of known species （either S. zeamais or S. oryzae）. Both identification strategies provided the same results indicating preva- lence of the maize weevil S. zeamais throughout the country. Two hypotheses may explain such prevalence：（i） the likely host preference ofS. zeamais for maize because this is the most cultivated cereal in Brazil, and （ii） the prevalence ofS. zeamais in tropical regions as compared with S. oryzae, which is more disseminated in subtropical and temperate regions.

关键词： cytochrome oxidase subunit I distribution maize weevil rice weevil South America

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