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Itopride for gastric volume,gastric emptying and drinking capacity in functional dyspepsia

World Journal of Gastrointestinal Pharmacology and Therapeutics 2017年第1期8卷 74-80页

作者： Shahab Abid Wasim Jafri maseeh uz zaman Rakhshanda Bilal Safia Awan Aamir Abbas Department of Medicine Aga Khan University Department of Radiology Aga Khan University Pakistan Atomic Energy Commission

AIMTo study the effect of itopride on gastric accommodation, gastric emptying and drinking capacity in functional dyspepsia (FD). METHODSRandomized controlled trial was conducted to check the effect of itopride on gastric accommodation, gastric emptying, capacity of tolerating nutrient liquid and symptoms of FD. We recruited a total of 31 patients having FD on the basis of ROME III criteria. After randomization, itopride was received by 15 patients while 16 patients received placebo. Gastric accommodation was determined using Gastric Scintigraphy. 13C labeled octanoic breadth test was performed to assess gastric emptying. Capacity of tolerating nutrient liquid drink was checked using satiety drinking capacity test. The intervention group comprised of 150 mg itopride. Patients in both arms were followed for 4 wk. RESULTSMean age of the recruited participant 33 years (SD = 7.6) and most of the recruited individuals, i.e., 21 (67.7%) were males. We found that there was no effect of itopride on gastric accommodation as measured at different in volumes in the itopride and control group with the empty stomach (P = 0.14), at 20 min (P = 0.38), 30 min (P = 0.30), 40 min (P = 0.43), 50 min (P = 0.50), 60 min (P = 0.81), 90 min (P = 0.25) and 120 min (P = 0.67). Gastric emptying done on a sub sample (n = 11) showed no significant difference (P = 0.58) between itopride and placebo group. There was no significant improvement in the capacity to tolerate liquid in the itopride group as compared to placebo (P = 0.51). Similarly there was no significant improvement of symptoms as assessed through a composite symptom score (P = 0.74). The change in QT interval in itopride group was not significantly different from placebo (0.10). CONCLUSIONOur study found no effect of itopride on gastric accommodation, gastric emptying and maximum tolerated volume in patients with FD.

关键词： Itopride Gastric emptying Gastric accommodation Functional dyspepsia Dyspepsia

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Role of Ca^(2+) on Growth of Brassica campestris *** ***(L.) Czern & Coss under Na^+ Stress

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Journal of Integrative Plant Biology 2010年第6期52卷 549-555页

作者： Badr-uz-zaman M.Salim Rehana Asghar Land Resources Research Programme Institute of Natural Resources and Environmental SciencesNational Agricultural Research Centre Department of Botany University of Arid Agriculture

Root and shoot growth of Brassica campestris L. and B. juncea increased significantly （P 〈 0.01） with enhanced Ca2＋ treatment along with 60 mM NaCl in the root medium. The maximum fresh mass of shoot and root in *** was recorded at 10 mM Ca2＋ concentration. The relative growth rate of shoot of both species reached its maximum at 8 mM of Ca2＋ concentration. Average rate of Ca2＋ intake （lCa） was higher in B. juncea than 6. campestris. In B. juncea, the average transport of Ca2＋ to shoot increased by 19%, 38%, 119%, 125% and 169% compared with the control. Furthermore specific utilization rate of Ca2＋ was higher in B. juncea than B. campestris. In B. campestris it increased by 9%, 32%, 41% and 59% at 4, 6, 8, and 10 mM of calcium in comparison to 2 mM Ca2＋ treatment. At 4, 6, 8 and 10 mM of Ca2＋ application, the increase in the leaf area ratio was 10,17, 23 and 30%, respectively. In the shoot and root portions of B. campestris and ***, Ca2＋ had a linear relationship with potassium and sulfur, whereas it was in antagonism with sodium ion.

关键词： Coss under Na Czern Stress

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Seismic fragility assessment of existing sub-standard low strength reinforced concrete structures

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Earthquake Engineering and Engineering Vibration 2015年第3期14卷 439-452页

作者： Sohaib Ahmad Nicolas Kyriakides Kypros Pilakoutas Kyriacos Neocleous Qaiser uz zaman Dept. of Civil and Structural Engineering University of Sheffield Dept. of Civil Engineering and Geomatics Cyprus University of Technology Dept. of Civil and Environmental Engineering University of Engineering and Technology

An analytical seismic fragility assessment framework is presented for the existing low strength reinforced concrete structures more common in the building stock of the developing *** realistic modelling of such substandard structures,low strength concrete stress-strain and bond-slip capacity models are included in calibrating material *** capacity parameters are generated stochastically to produce building population and cyclic pushover analysis is carried out to capture inelastic *** period values are evaluated corresponding to each displacement step on the capacity curves and used as seismic demand.A modified capacity demand diagram method is adopted for the degrading structures,which is further used to evaluate peak ground acceleration from back analysis considering each point on the capacity curve as performance *** developing fragility curves,the mean values of peak ground acceleration are evaluated corresponding to each performance point on the series of capacity curves.A suitable probability distribution function is adopted for the secant period scatter at different mean peak ground acceleration values and probability of exceedance of limit states is evaluated.A suitable regression function is used for developing fragility curves and regression coefficients are proposed for different confidence *** curves are presented for a low rise pre-seismic code reinforced concrete structure typical of developing countries.

关键词： analytical fragility damage index non-engineered b

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Sub-nanoscale Engineering of MoO_(2) Clusters for Enhanced Sodium Storage

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Energy & Environmental Materials 2023年第1期6卷 155-163页

作者： Yang Liu Shichao Wang Xuan Sun Jinyang Zhang Fakhr uz zaman Linrui Hou Changzhou Yuan School of Materials Science and Engineering University of JinanJinan 250022China

Smart construction of battery-type anodes with high rate and good mechanical properties is significant for advanced sodium ion capacitors(SICs).Herein,a flexible film consisting of MoO_(2) subnanoclusters encapsulated in nitrogen-doped carbon nanofibers(MoO_(2) SCs@N-CNFs)is designed and synthesized via electrospinning toward SICs as *** strong N-Mo interaction guarantees the stable yet uniform dispersion of high loading MoO_(2) SCs(≈40 wt.%)in the flexible carbonaceous *** sub-nanoscale effect of SCs restrains electrode pulverization and improves the Na+diffusion kinetics,rendering better pseudocapacitance-dominated Na+-storage properties than the nanocrystal *** MoO_(2) SCs@N-CNFs paper with mass loadings of 2.2–10.1 mg cm^(−2) can be directly used as free-standing anode for SICs,which exhibit high reversible gravimetric/areal capacities both in liquid and quasi-solid-state *** assembled flexible SICs competitively exhibit exceptional energy density and cycling *** significantly,the sub-nanoscale engineering strategy here is promisingly generalized to future electrode design for other electrochemical energy-related applications and beyond.

关键词： flexible film electrodes high areal mass loading anodes MoO_(2)subnanoclusters sodium ion capacitors

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Calculation and analysis of assembly clearance based on nonideal surface discrete data

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International Journal of Modeling, Simulation, and Scientific Computing 2017年第2期8卷 255-263页

作者： Yue Li Lihong Qiao uzair Khaleeq uz zaman Ali Siadat School of Mechanical Engineering and Automation Beihang University Engineering Research Center of Complex Product Advanced Manufacturing System Ministry of EducationP.R.China Laboratoire de Conception Fabrication Commande(LCFC)Ecole Nationale Superieure d’Arts et Metiers(ENSAM) MetzFrance

Calculation of assembly clearance is the basis of analysis on assembly problems,and the real assembly surface is the nonideal *** this paper,the concept of assembly clearance on nonideal surface is defined and the calculation algorithm of assembly clearance is *** on the calculation,the concept of clearance surface is put forward to express the distribution of assembly clearance on nonideal surface as it can assist the analysis of assembly ***,the effectiveness of the algorithm is verified by the calculation of the assembly clearance between the surfaces of piston and cylinder.

关键词： Assembly problem nonideal surface clearance surface

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Lax Pairs and Integrability Conditions of Higher-Order Nonlinear Schrdinger Equations

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Communications in Theoretical Physics 2016年第8期65卷 171-178页

作者： M.Asad-uz-zaman H.Chachou Samet U.Al Khawaja Physics Department United Arab Emirates University Laboratory for Theoretical Physics and Material Physics Faculty of SciencesHassiba Benbouali University of Chlef

We derive the Lax pairs and integrability conditions of the nonlinear Schrdinger equation with higher-order terms, complex potentials, and time-dependent coefficients. Cubic and quintic nonlinearities together with derivative terms are considered. The Lax pairs and integrability conditions for some of the well-known nonlinear Schrdinger equations, including a new equation which was not considered previously in the literature, are then derived as special cases. We show most clearly with a similarity transformation that the higher-order terms restrict the integrability to linear potential in contrast with quadratic potential for the standard nonlinear Schrdinger equation.

关键词： exact solutions Lax pair integrability

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A two step facile synthesis of new steroidal linear and angular pyranones having anti-mycobacterial activity

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Chinese Chemical Letters 2009年第2期20卷 153-157页

作者： Shams-uz-zaman Tabassum Siddiqui Mohd.Gulfam Alam Najmul Islam Department of Chemistry(Steroid Lab) Aligarh Muslim University Department of Biochemistry Faculty of medicineJ.N.Medical College

Title compounds 2′,2′-dimethylcholesta-2,4-dien[3,2-b]-pyran-4′-one （3）, 2′,2′-dimethyl-3β-substituted cholesta-4,6-dien[7,6- b]-pyran-4′-one （6a,b） and （6c） were prepared by the cyclization of 2-acetylcholesta-2,4-dien-3-ol （2）, 6-acetyl-3β-substituted- cholesta-4,6-dien-7-ol （Sa,b） and （5c） respectively, with pyrrolidine, dry benzene and dry acetone using Dean Stark separator through conventional heating. Furthermore, compounds were also found to be active against Mycobacterium tuberculosis.

关键词： Steroidal linear and angular pyranones Acetyl hydroxy derivative of steroids Pyrrolidine Acetyl chloride Dean Stark separator Anti-mycobacterial activity

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A Diagnostic Study of Record Heavy Rain in Twin Cities Islāmābad-Rāwalpindi

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Advances in Atmospheric Sciences 2004年第6期21卷 976-988页

作者： Ghulam RASUL Qamar-uz-zaman CHAUDHRY 赵思雄曾庆存 Meteorological Service of Pakistan P. O. Box 1214 Islāamāabad-Pakistan Institute of Atmospheric Physics Chinese Academy of Sciences Beijing 100029 Graduate School Chinese Academy of Sciences Beijing 100039

Using surface and NCEP reanalysis data along with radar and satellite images, diagnosis has been carried out to probe the reasons for the very heavy rainfall that occurred in Islāmābad-Rāwalpindi on 23 July 2001. It has been revealed that the sudden evolution of this meso-scale severe weather system was the direct result of strong surface convection in moist and unstable lower layers of the atmosphere. The subsequent rapid development was the combined effect of the presence of the mid latitude westerly’s trough in the north and moisture feeding through monsoon flow along the Himalayas and also the direct south-westerly current from the Arabian Sea. After the westward shifting of the Sub-Tropical High (STH) from the north of India, the strong divergence zone on its eastern edge contributed positively to the development of upward motion. Initially the convective systems moved towards the south and then southeastward following the steering current in the middle troposphere. Based on these analyses, the physical model of the sudden record heavy rainfall has been proposed and a comparison between the heavy rainfall in this case and one in China has been conducted.

关键词： monsoon circulation mesoscale systems heavy rainfall

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Modeling the density gradient of 3D nanofiber scaffolds fabricated by divergence electrospinning

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Advances in Manufacturing 2021年第3期9卷 414-429页

作者： Muhammad Adib uz zaman Dilshan Sooriyaarachchi Ying-Ge Zhou George Z.Tan Dong-Ping Du Department of Industrial Manufacturing and Systems EngineeringTexas Tech UniversityLubbockTXUSA

Following recent insights on structure-cell-function interactions and the critical role of the extracellular matrix(ECM),the latest biofabrication approaches have increasingly focused on designing materials with biomimetic *** electrospinning is a novel fabrication method for three-dimensional(3D)nanofiber *** is introduced to produce 3D nanofiber mats that have numerous applications in regenerative medicine and tissue *** of the most important characteristics of 3D nanofiber mats is the density *** study provides a statistical analysis and response surface modeling framework based on experimental data to evaluate the manner by which the geometric designs of double-bevel collectors influence the fiber density ***,variance of analysis and sensitivity analysis were performed to identify parameters that had significant effects,and a response surface model embedded with seven location indicators was developed to predict the spatial distribution of fiber density for different collector *** was concluded that the collector height,bevel angle,and their interactions were significant factors influencing the density *** study revealed the sensitivity of system configuration and provided an optimization tool for process controllability of microstructure gradients.

关键词： Electrospinning 3D nanofiber scaffold Statistical model Design of experiments Response surface method

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Depositional facies and reservoir characteristics of the Early Cretaceous Lower Goru Formation,Lower Indus Basin Pakistan:Integration of petrographic and gamma-ray log analysis

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Petroleum 2023年第3期9卷 331-341页

作者： Qamar uz zaman Dar Pu Renhai Shahid Ghazi Shakeel Ahme Rana Imran Ali Mubashir Mehmood Department of Geology Northwest UniversityXi'an710069China Institute of Geology University of the PunjabLahore54000Pakistan Oil and Gas Development Company Limited Islamabad44000Pakistan Kuwait Foreign Petroleum Exploration Company(Kufpec) Islamabad44000Pakistan Department of Geology Abdul Wali Khan UniversityMardan23130Pakistan

The sand intervals of the Early Cretaceous Lower Goru Formation are a conventional reservoir,generally distributed in the Middle and Lower Indus Basin of *** formation is classified into two parts;the upper parts are predominantly composed of shale,siltstone,and thin layers of alternate shale and sandstone,while the lower parts are composed of sandstone with interlayering of shale and *** sandstone of the Lower Goru Formation has been further divided into A,B,C,and D sand intervals based on reservoir *** depositional facies and reservoir characteristics are essential for the evaluation of hydrocarbon exploration and *** paper aims to evaluate the depositional environment and reservoir characterization of the siliciclastic reservoir of the Early Cretaceous Lower Goru Formation by integrating the gamma-ray log patterns and petrographic analysis and scanning electron microscopic(SEM)*** characterization of the sand intervals and Gamma-ray log signatures were used for the interpretation of the depositional environment of the reservoir *** analysis reveals that the sandstone of the Lower Goru Formation is fine-to medium-grained,well-sorted,arkose or feldspathic *** intergranular macroporosity,secondary intragranular macropores,and Intercrystalline micropores were identified within the sandstone by the SEM *** diagenetic analysis suggests that the sandstone possesses high porosity,low permeability,and has undergone significant alterations such as compaction,quartz cementation,feldspar dissolution,and clay minerals *** electrofacies are interpreted based on gamma-ray log patterns including(1)funnel shape(FA);(2)bell shape(FB);(3)cylindrical shape(FC);(4)bow shape(FD);and(5)serrated shape(FE)*** interpreted facies results reveal shoreface environment for A-sand,Tidal flat for B-sand,mixed tidal flat for C sand,Tide dominated mixed fo

关键词： Depositional facies Early cretaceous Electrofacies Gamma-ray pattern Lower goru Petrographic analysis

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