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Effects of Hyperventilation on Venous-Arterial Bicarbonate Concentration Difference: A Possible Pitfall in Venous Blood Gas Analysis

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International Journal of Clinical Medicine 2014年第2期5卷 76-80页

作者： Akira Umeda Kazuteru Kawasaki Tadashi Abe Tateki yamane Yasumasa Okada Department of Internal Medicine International University of Health and Welfare Shioya Hospital Yaita Japan Department of Respiratory Medicine National Center for Child Health and Development Tokyo Japan Division of Internal Medicine Murayama Medical Center Musashimurayama Japan Division of Respiratory Medicine Department of Medicine Tokai University School of Medicine Isehara Japan

Objectives: Recent reports on venous blood gas analysis have shown that venous bicarbonate concentration is useful in the evaluation of the body acid-base status. Most of these reports have been based on the Bland-Altman analysis comparing arterial and venous blood gas values. We intended to elucidate any factors that decrease the agreement between venous and arterial bicarbonate concentrations, which might impair the usefulness of venous blood gas analysis. Methods: Healthy volunteers and patients with various diseases (n = 141) were evaluated by simultaneous arterial and venous blood sampling and Bland-Altman analysis. The venous-arterial bicarbonate concentration difference was compared between healthy volunteers and untreated respiratory alkalosis patients. Intentional hyperventilation (30 or 60 breaths/min, for 3 min) was also performed on 6 healthy volunteers and the venous-arterial bicarbonate concentration difference was evaluated. Results: The relative average bias in bicarbonate concentration was 2.00 mEq/l with venous bicarbonate higher than arterial bicarbonate with 95% limits of agreement of ±4.15 mEq/l. Hyperventilation challenges increased the venous-arterial bicarbonate concentration difference in an intensity-dependent manner. The venous-arterial bicarbonate concentration difference was higher in untreated respiratory alkalosis patients than in healthy volunteers (P Conclusion: Although venous bicarbonate may be useful to evaluate the body acid-base status, hyperventilation increases the venous-arterial bicarbonate concentration difference. Physicians should keep this phenomenon in mind.

关键词： Hyperventilation Bicarbonate Bland-Altman Analysis Venous Blood Gas Analysis

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Fiber Formation of Poly（tetrafluoroethylene） from its Emulsion

Fiber Formation of Poly（tetrafluoroethylene） from its Emul...

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第六届国际高技术高分子材料学术会议

作者： Hideki yamane Yoshito Takagi Takashi Wano Daisuke Kitagawa Grad.School of Sci.& Tech. Kyoto Institute of Technology

＜正＞*** Poly（tetrafluoroethylene）（PTFE）has been known to have various superior properties such as thermal stability,chemical resistance,weather resistance

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Development of highly sensitive and rapid antigen detection assay for diagnosis of COVID-19 utilizing optical waveguide immunosensor

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Journal of Molecular Cell Biology 2021年第10期13卷 763-766页

作者： Rikako Funabashi Kei Miyakawa Yutaro Yamaoka Seiko Yoshimura Satoshi yamane Sundararaj Stanleyraj Jeremiah Kohei Shimizu Hiroki Ozawa Chiharu Kawakami Shuzo Usuku Nobuko Tanaka Etsuko Yamazaki Hirokazu Kimura Hideki Hasegawa Akihide Ryo Department of Microbiology Yokohama City University Graduate School of MedicineKanagawajapan Life Science Laboratory Technology and Development DivisionKanto Chemical Co.Inc.KanagawaJapan Primary Care Testing Solution Development Department Canon Medical Systems CorporationTochigiJapan Yokohama City Institute of Public Health KanagawaJapan Clinical Laboratory Department Yokohama City University HospitalKanagawaJapan Department of Health Science Gunma Paz University Graduate SchoolGunmajapan Center for Influenza and Respiratory Virus Research National Institute of Infectious DiseasesMusashimurayamaTokyoJapan

Ever since its outbreak,the COVID-19 pandemic caused by SARS-CoV-2 has been spreading rapidly causing a global health *** diagnosis and instituting appropriate intervention to relevant individuals are essential not only to slow down the spread of this pandemic but also to manage our resources *** date,testing for SARS-CoV-2 infection mostly relies on reverse transcription-quantitative polymerase chain reaction(RT-qPCR)on a nasopharyngeal or saliva specimen and remains the gold standard for diagnosis as it exhibits high sensitivity and specificity.

关键词： diagnosis specificity nasopharyngeal

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Prevalence of nonalcoholic fatty liver disease and its association with age in patients with type 2 diabetes mellitus

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World Journal of Hepatology 2022年第6期14卷 1226-1234页

作者： Ryosuke yamane Kentaro Yoshioka Kazuhiko Hayashi Yuko Shimizu Yuki Ito Komei Matsushita Michiyo Yoshizaki Go Kajikawa Taro Mizutani Atsuko Watarai Kosuke Tachi Hidemi Goto Department of Gastroenterology and Hepatology Federation of National Public Service Personnel Mutual Aid Associations Meijo HospitalNagoya 460-0001AichiJapan Center for Liver Diseases Federation of National Public Service Personnel Mutual Aid Associations Meijo HospitalNagoya 460-0001AichiJapan Department of Diabetes and Endocrinology Federation of National Public Service Personnel Mutual Aid Associations Meijo HospitalNagoya 460-0001AichiJapan

BACKGROUND Type 2 diabetes mellitus(T2DM)is a risk factor for nonalcoholic fatty liver disease(NAFLD).AIM To determine the prevalence and clinical correlates of NAFLD in a large cohort of patients with *** Four hundred thirty-seven participants with T2DM who consulted at Meijo Hospital from April 2019 to September 2020 and underwent computed tomography(CT)were *** mean age was 74±13 years,and 269 were *** attenuation minus splenic attenuation(CTL−S)less than 1 Hounsfield unit was considered fatty *** was defined as fatty liver in the absence of significant alcohol consumption and hepatitis virus infection.A multiple logistic regression was used to assess the independent factors associated with *** NAFLD was identified in 25.2%of the *** age(odds ratio[OR]=−0.945;95%confidence interval[CI]:0.922–0.969),higher hemoglobin levels(OR=1.501,95%CI:1.278–1.764),lower high-density lipoprotein(HDL)cholesterol levels(OR=0.971,95%CI:0.953–0.989),and the absence of dialysis(OR=0.109,95%CI:0.014–0.856)were independent predictors of *** NAFLD was detected with CT in 25.2%of the *** was associated with younger age,higher hemoglobin levels,lower HDL cholesterol levels,and an absence of dialysis.

关键词： Age Computed tomography Dialysis Hemoglobin Nonalcoholic fatty liver disease Type 2 diabetes mellitus

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A ruptured large extraluminal ileal gastrointestinal stromal tumor causing hemoperitoneum

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World Journal of Gastroenterology 2008年第18期14卷 2928-2931页

作者： Shoji Hirasaki Kohei Fujita Minoru Matsubara Hiromitsu Kanzaki Hiromichi yamane Masato Okuda Seiyuu Suzuki Atsuko Shirakawa Hideyuki Saeki Department of Internal Medicine Sumitomo Besshi Hospital Niihama 7928543 Japan Department of Pathology Sumitomo Besshi Hospital Niihama 7928543 Japan Department of Surgery Sumitomo Besshi Hospital Niihama 7928543 Japan

We describe an 87-year-old woman with a large ileal gastrointestinal stromal tumor (GIST) causing hemoperitoneum. A CT scan demonstrated a large heterogeneous mass measuring about 13 cm × 11 cm in the pelvis and hemoperitoneum, with a non-uniform enhancement pattern. The mass was diagnosed as a GIST originating from the gastrointestinal tract. She underwent an urgent laparotomy and an ileal GIST with a rupture was found 130 cm from the anal to the Treitz’s ligament. Hemoperitoneum caused by ileal GIST rupture is a rare condition. Bleeding in the large tumor leading to rupture of the capsule might cause hemoperitoneum in the present case.

关键词： Intestinal neoplasm Small intestine Extraluminal growth Laparotomy

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Radiofrequency Ablation-Associated Delayed Diaphragmatic Hernia Treated with the Thoracolaparotomy Approach: A Case Report

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Case Reports in Clinical Medicine 2016年第12期5卷 541-547页

作者： Hiroaki yamane Toshihiko Kohashi Ichiro Omori Akira Nakashima Eisuke Murakami Koji Waki Hidenori Mukaida Naoki Hirabayashi Department of Gastroenterological Surgery Hiroshima City Asa Citizens Hospital Hiroshima Japan Department of Gastroenterological and Transplant Surgery Applied Life Sciences Institute of Biomedical and Health Sciences Hiroshima University Hiroshima Japan Department of Gastroenterology Hiroshima City Asa Citizens Hospital Hiroshima Japan

Background: Radiofrequency ablation (RFA) is an effective treatment for hepatocellular carcinoma (HCC). However, rare but serious complications may occur after RFA. We describe a case of diaphragmatic hernia associated with RFA. Case Presentation: A 68-year-old man with a history of hepatitis C-related liver cirrhosis was admitted to our hospital because of lower abdominal pain. Three years earlier, he underwent RFA for HCC in segment 8. Computed tomography revealed that the intestine was intruding into the right thoracic cavity through a diaphragmatic hernia. On the basis of the diagnosis of right diaphragmatic hernia with a strangulated ileus, an emergency operation was performed. Perforation of the strangulated transverse colon into the right thoracic cavity was suspected, and a combined approach of laparotomy and thoracotomy was utilized. The operative findings showed that the diaphragmatic hernia was 3.5 × 2.0 cm in diameter, and it was simply sutured with a nonabsorbable suture material. Resection of the intruded ischemic transverse colon was completed, and a covering ileostomy was performed. The patient was discharged without any complications. Conclusions: RFA is widely used for the treatment of HCC. Reports of early- and late-phase complications indicate that heat damage contributes to the fragility of neighboring organs. The occurrence of diaphragmatic hernia after RFA is one of the delayed complications. Although it rarely occurs, this complication requires emergency surgery. In conclusion, if perforation of the intestine into the thoracic cavity is suspected, thoracolaparotomy should be considered as a treatment option to prevent postoperative massive empyema.

关键词： Diaphragmatic Hernia Hepatocellular Carcinoma Radiofrequency Ablation

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Clinical Impact of Bacteremia Due to <i>Staphylococcus saprophyticus</i>

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Advances in Infectious Diseases 2021年第1期11卷 6-12页

作者： Daisuke Tamura Hiroaki yamane Hikaru Tabakodani Hirokazu Yamagishi Erika Nakazato Yumiko Kimura Masayoshi Shinjoh Takanori Yamagata Department of Pediatrics Jichi Medical University Tochigi Japan Department of Clinical laboratory Jichi Medical University Hospital Tochigi Japan Department of Pediatrics Keio University School of Medicine Tokyo Japan

Objective: This was a retrospective study to evaluate the clinical impact of bacteremia due to Staphylococcus saprophyticus and identify which factors influence it. Methods: We reviewed all patients with bacteremia due to S. saprophyticus over the last 12 years. This study was performed at Jichi Medical University Hospital in Japan, a key hospital in the northern Kanto area including Tochigi, Gunma, Ibagagi, and northern Saitama prefectures. We retrospectively reviewed the blood culture results and medical records of all patients with a history of visits or hospitalizations between April 2008 and September 2020. Results: During the study period, 4 blood culture specimens were considered to have S. saprophyticus bacteremia. Two of these were from subjects > 60 years old who had severe infection. A third case, 27 years old, was thought to have a catheter-related bloodstream infection;however, the only symptom was fever, which was not serious. The fourth case, a previously unreported pediatric patient, had non-severe fever. The mean time for a diagnosis of bacteremia by blood culture testing was 42 hours, whereas contamination appeared in cultures after another 50 hours. Conclusion: The pathogenicity of S. saprophyticus might be lower in the blood than in the urine due to its physiological function and activity. In older adults with underlying diseases, the severity of bacteremia was more pronounced, whereas in a young adult and a child, the disease was relatively mild. Age and underlying disease might be useful factors to consider when diagnosing bacteremia due to S. saprophyticus.

关键词： Gram-Positive Staphylococcus Coagulase-Negative Staphylococcus Staphylococcus saprophyticus Bacteremia

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“东丽卡”T1000超高强度碳纤维及其复合材料性能

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固体火箭技术 1987年第4期 51-55页

作者： Shoji yamane 钟铭安

高强度、中摸量碳纤维“东丽卡”T1000已研制成功。用树脂浸渍束丝试样,测得的T1000纤维的拉伸强度>7GPa,拉伸弹性模量为294GPa,断裂极限伸长率为2.4％。它的高拉伸强度很好地反映于其复合材料中。当它同合适的树脂系统结合时,得到的复... 详细信息

高强度、中摸量碳纤维“东丽卡”T1000已研制成功。用树脂浸渍束丝试样,测得的T1000纤维的拉伸强度>7GPa,拉伸弹性模量为294GPa,断裂极限伸长率为2.4％。它的高拉伸强度很好地反映于其复合材料中。当它同合适的树脂系统结合时,得到的复合材料拉伸强度达3.5～3.8GPa。断裂伸长率达2.0％。

关键词：高强度纤维碳纤维碳纤维增强复合材料

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TELOMERASE ACTIVITY IN ORAL PREMALIGNANT LESIONS AND ORAL SQUAMOUS CELL CARCINOMAS

TELOMERASE ACTIVITY IN ORAL PREMALIGNANT LESIONS AND ORAL SQ...

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第二届中国国际暨第五届全国口腔颌面外科学术会议

作者： T.MITUYASU K.yamane S.OZEKI M.OHISHI FIRST DEPARTMENT OF OMFS FACULTY OF DENTISTRY KYUSHU UNIVERSITY FUKUOKA JAPAN FIRST DEPARTMENT OF OMFS FACULTY OF DENTISTRY KYUSHU UNIVERSITY FUKUOKA JAPAN FIRST DEPARTMENT OF OMFS FACULTY OF DENTISTRY KYUSHU UNIVERSITY FUKUOKA JAPAN FIRST DEPARTMENT OF OMFS FACULTY OF DENTISTRY KYUSHU UNIVERSITY FUKUOKA JAPAN

OBJECTIVE:Telomerase,an RNA-containing enzyme,is associated with cellular immortality and ***, telomerase activity has been detected in both cancers and some noncancerous ***:In the present study,we analyzed the telomerase activity in 37 samples,including oral squamous cell carcinoma and premalignant lesions and adjacent tissues to carcinoma by using the sensitive telomeric repeat amplification protocol assay. RESULTS:Telomerase

关键词： TELOMERASE ACTIVITY IN ORAL PREMALIGNANT LESIONS AND ORAL SQUAMOUS CELL CARCINOMAS

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Noise Reduction of Optical Pulses Using Variable Spectral Filters and Optical Fibers

Noise Reduction of Optical Pulses Using Variable Spectral Fi...

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亚太地区通信会议暨光电子通信会议

作者： N.Nishizawa M.Mori T.Goto K.yamane Department of Quantum Engineering Nagoya University Nagoya 464-8603 Japan Department of Information Network Engineering Aichi Institute ot Technology Toyota470-0392Japan Department of Quantum Engineering Nagoya University Nagoya 464-8603 Japan Lightwave Transmission Engineering Department Fujitsu Ltd. Kawasaki 211-8588 Japan

Noise reduction of optical pulses using variablespectral filters and optical fibers is investigated. lntensitynoise of fiber laser is reduced by 23 dB using band-passfilter and reaches the shot noise level.

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