Development of highly sensitive and rapid antigen detection assay for diagnosis of COVID-19 utilizing optical waveguide immunosensor

作     者：Rikako Funabashi Kei Miyakawa Yutaro Yamaoka Seiko Yoshimura Satoshi Yamane Sundararaj Stanleyraj Jeremiah Kohei Shimizu Hiroki Ozawa Chiharu Kawakami Shuzo Usuku Nobuko Tanaka Etsuko Yamazaki Hirokazu Kimura Hideki Hasegawa Akihide Ryo Rikako Funabashi;Kei Miyakawa;Yutaro Yamaoka;Seiko Yoshimura;Satoshi Yamane;Sundararaj Stanleyraj Jeremiah;Kohei Shimizu;Hiroki Ozawa;Chiharu Kawakami;Shuzo Usuku;Nobuko Tanaka;Etsuko Yamazaki;Hirokazu Kimura;Hideki Hasegawa;Akihide Ryo

作者机构：Department of MicrobiologyYokohama City University Graduate School of MedicineKanagawajapan Life Science LaboratoryTechnology and Development DivisionKanto Chemical Co.Inc.KanagawaJapan Primary Care Testing Solution Development DepartmentCanon Medical Systems CorporationTochigiJapan Yokohama City Institute of Public HealthKanagawaJapan Clinical Laboratory DepartmentYokohama City University HospitalKanagawaJapan Department of Health ScienceGunma Paz University Graduate SchoolGunmajapan Center for Influenza and Respiratory Virus ResearchNational Institute of Infectious DiseasesMusashimurayamaTokyoJapan 

出 版 物：《Journal of Molecular Cell Biology》 (分子细胞生物学报（英文版）)

年 卷 期：2021年第13卷第10期

页      面：763-766页

核心收录：

学科分类：080202[工学-机械电子工程] 08[工学] 0802[工学-机械工程] 

基　　金：supported in port by Japan Agency for Medical Research and Development(AMED,IP19fk0108110 and JP20he0522001) by Health Labour Sciences research grant from the Ministry of Health Labour and Welfare(19HA1003) 

主　　题：diagnosis specificity nasopharyngeal 

摘      要：Ever since its outbreak,the COVID-19 pandemic caused by SARS-CoV-2 has been spreading rapidly causing a global health *** diagnosis and instituting appropriate intervention to relevant individuals are essential not only to slow down the spread of this pandemic but also to manage our resources *** date,testing for SARS-CoV-2 infection mostly relies on reverse transcription-quantitative polymerase chain reaction(RT-qPCR)on a nasopharyngeal or saliva specimen and remains the gold standard for diagnosis as it exhibits high sensitivity and specificity.